Definition Clostridium tetani E88 chromosome, complete genome.
Accession NC_004557
Length 2,799,251

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The map label for this gene is yhdH [H]

Identifier: 28210880

GI number: 28210880

Start: 1271359

End: 1272675

Strand: Direct

Name: yhdH [H]

Synonym: CTC01190

Alternate gene names: 28210880

Gene position: 1271359-1272675 (Clockwise)

Preceding gene: 28210877

Following gene: 28210882

Centisome position: 45.42

GC content: 35.61

Gene sequence:

>1317_bases
ATGAAAAATAATAGAGATAGTTTTGAATCCAAGATTGGTTTTATTTTAGCATGCATAGGTTCAGCAGTAGGTATGGGAAA
TATTTGGTTATTTCCTTATCGTGTAGGGCAGTTTGGGGGGGCGGCATTTTTAATACCTTATATTATATTCGTTGTGGTTA
TTGGATTTACAGGAGTTATTGGGGAAATGTCCTTTGGTCGTGCAATGGGAACAGGACCAGTTGGAGCATTTAAAAAGGCA
TTAGAGAAAAGGGGAAAAAAGCATGGAGATCTTATTGGACTTATTCCAGTAATAGGTTCTCTAGGCATTGCCATAGGATA
TTCAGTAGTTGTAGGATGGATACTTAGATTTACCGTAGGAACTATTACTGGTTCAATGATAAAAGCACCAGATAGTGGTG
TGTATTTTGCTTCTATTGCTGGAAAACTAGGAAGTCTTAGTTGGCATCTTTTAGCATTGGCATTAACCTTTATCATTATG
ACTATGGGTGTTTCTAAGGGAATAGAAAAGGTTAATAAGATTATGATGCCTGCTTTTTTTGTGTTGTTTTTAATTCTTGC
AATCAGTGTTGGAGCATTACCAGGAGCTATAGAAGGATATAGATATTTGTTAGTTCCAAAATGGGAATTCCTTGGAGAGC
CTAAAACTTGGGTGTTTGCTCTAGGGCAGGCATTTTTCTCTCTTTCATTAGCGGGGTCAGGAACTGTAGTATATGGAAGT
TATTTAAAGAAAACTGAAAATATTGTACAAAGTGCAAAGTATGTGACTCTATTTGACACCTGTGCAGCAATGTTAGCAGC
ACTTGTAATCATACCATCAGTATTTGCCTTTGGTATGGATCCCACAGCAGGACCACCGCTTATGTTTATTATAATGCCTA
ACGTATTTAAGCAAATGCCTATGGGACAATTATCTGCAATTATATTCTTTTTAGCAGTTTTATTTGCAGGAATTACATCT
TTAATGAATCTATTTGAAAGCCCAATAGAGGCATTACAAGAGAGATTTAACTTTTCTAGAAAAGCTTCAGTTTGTATTAT
TGCAATGATTGGGGCAGTTACAGGGATAATACTTGAAGATGCAAACAAACTTGGTATTTGGATGGACGTAATATCTATTT
ATGTTATTCCTTTGGGGGCACTTCTTGCTGGCATTATGTTTTTCTGGATTTGTGGTTCAAAATTTGCAAGAGAACAGGCG
CAATTAGGTAATAATAAGGAAATAGGTTCTTGGTTTGAACCTATGACAAAATATGCATTTTGTGGACTTACAATTATAGT
TTATATTCTTGGAATATTTTATGGAGGCATTGGATAA

Upstream 100 bases:

>100_bases
ACTTAAAATGTTGAAATATCACAGTTTTTTTCTATTGATTAGCTAAAAAGTGGGATAAAACATTAGATAATAAAGATTAT
AATATACAAGGGGGCGTATT

Downstream 100 bases:

>100_bases
ATTTATTTAATGAAGAATTAATAAAAACACCTCATTTCATGTTAATAGTTGAAATATTAACATGAAATGAGGTGTTTTTA
TTGCTAGTAGAAAAATAAGA

Product: sodium-dependent amino acid transporter (proline, tryptophan)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MKNNRDSFESKIGFILACIGSAVGMGNIWLFPYRVGQFGGAAFLIPYIIFVVVIGFTGVIGEMSFGRAMGTGPVGAFKKA
LEKRGKKHGDLIGLIPVIGSLGIAIGYSVVVGWILRFTVGTITGSMIKAPDSGVYFASIAGKLGSLSWHLLALALTFIIM
TMGVSKGIEKVNKIMMPAFFVLFLILAISVGALPGAIEGYRYLLVPKWEFLGEPKTWVFALGQAFFSLSLAGSGTVVYGS
YLKKTENIVQSAKYVTLFDTCAAMLAALVIIPSVFAFGMDPTAGPPLMFIIMPNVFKQMPMGQLSAIIFFLAVLFAGITS
LMNLFESPIEALQERFNFSRKASVCIIAMIGAVTGIILEDANKLGIWMDVISIYVIPLGALLAGIMFFWICGSKFAREQA
QLGNNKEIGSWFEPMTKYAFCGLTIIVYILGIFYGGIG

Sequences:

>Translated_438_residues
MKNNRDSFESKIGFILACIGSAVGMGNIWLFPYRVGQFGGAAFLIPYIIFVVVIGFTGVIGEMSFGRAMGTGPVGAFKKA
LEKRGKKHGDLIGLIPVIGSLGIAIGYSVVVGWILRFTVGTITGSMIKAPDSGVYFASIAGKLGSLSWHLLALALTFIIM
TMGVSKGIEKVNKIMMPAFFVLFLILAISVGALPGAIEGYRYLLVPKWEFLGEPKTWVFALGQAFFSLSLAGSGTVVYGS
YLKKTENIVQSAKYVTLFDTCAAMLAALVIIPSVFAFGMDPTAGPPLMFIIMPNVFKQMPMGQLSAIIFFLAVLFAGITS
LMNLFESPIEALQERFNFSRKASVCIIAMIGAVTGIILEDANKLGIWMDVISIYVIPLGALLAGIMFFWICGSKFAREQA
QLGNNKEIGSWFEPMTKYAFCGLTIIVYILGIFYGGIG
>Mature_438_residues
MKNNRDSFESKIGFILACIGSAVGMGNIWLFPYRVGQFGGAAFLIPYIIFVVVIGFTGVIGEMSFGRAMGTGPVGAFKKA
LEKRGKKHGDLIGLIPVIGSLGIAIGYSVVVGWILRFTVGTITGSMIKAPDSGVYFASIAGKLGSLSWHLLALALTFIIM
TMGVSKGIEKVNKIMMPAFFVLFLILAISVGALPGAIEGYRYLLVPKWEFLGEPKTWVFALGQAFFSLSLAGSGTVVYGS
YLKKTENIVQSAKYVTLFDTCAAMLAALVIIPSVFAFGMDPTAGPPLMFIIMPNVFKQMPMGQLSAIIFFLAVLFAGITS
LMNLFESPIEALQERFNFSRKASVCIIAMIGAVTGIILEDANKLGIWMDVISIYVIPLGALLAGIMFFWICGSKFAREQA
QLGNNKEIGSWFEPMTKYAFCGLTIIVYILGIFYGGIG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=404, Percent_Identity=26.980198019802, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI194018524, Length=306, Percent_Identity=30.0653594771242, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI92859670, Length=419, Percent_Identity=27.2076372315036, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4507041, Length=398, Percent_Identity=26.1306532663317, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI33354281, Length=303, Percent_Identity=27.3927392739274, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI58219014, Length=299, Percent_Identity=27.0903010033445, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4507043, Length=386, Percent_Identity=25.6476683937824, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI134304856, Length=389, Percent_Identity=24.9357326478149, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI21361581, Length=391, Percent_Identity=24.5524296675192, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI11181770, Length=308, Percent_Identity=27.5974025974026, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI51468073, Length=299, Percent_Identity=25.752508361204, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI7657587, Length=413, Percent_Identity=23.2445520581114, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI171184408, Length=413, Percent_Identity=25.6658595641646, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI171184406, Length=413, Percent_Identity=25.6658595641646, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI171184404, Length=413, Percent_Identity=25.6658595641646, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI289191351, Length=394, Percent_Identity=25.6345177664975, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4557046, Length=394, Percent_Identity=25.6345177664975, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI289191377, Length=394, Percent_Identity=25.6345177664975, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI5032097, Length=359, Percent_Identity=25.9052924791086, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI67782317, Length=368, Percent_Identity=25.2717391304348, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI218563756, Length=353, Percent_Identity=26.0623229461756, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI67782313, Length=368, Percent_Identity=25.2717391304348, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI67782315, Length=368, Percent_Identity=25.2717391304348, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI12408638, Length=282, Percent_Identity=25.531914893617, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI300360519, Length=346, Percent_Identity=23.6994219653179, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI21361693, Length=115, Percent_Identity=34.7826086956522, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI197276623, Length=350, Percent_Identity=24.5714285714286, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI54607094, Length=350, Percent_Identity=24.5714285714286, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554804, Length=372, Percent_Identity=26.0752688172043, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71998244, Length=339, Percent_Identity=26.2536873156342, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25146584, Length=395, Percent_Identity=23.5443037974684, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115534083, Length=477, Percent_Identity=22.4318658280922, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI133952791, Length=124, Percent_Identity=36.2903225806452, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17569475, Length=399, Percent_Identity=23.8095238095238, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17555248, Length=229, Percent_Identity=27.5109170305677, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI212642127, Length=298, Percent_Identity=24.1610738255034, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17535731, Length=124, Percent_Identity=34.6774193548387, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19921936, Length=413, Percent_Identity=28.0871670702179, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17136952, Length=384, Percent_Identity=26.8229166666667, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281364394, Length=384, Percent_Identity=26.8229166666667, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28574704, Length=384, Percent_Identity=26.8229166666667, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17136950, Length=384, Percent_Identity=26.8229166666667, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28574702, Length=384, Percent_Identity=26.8229166666667, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24661428, Length=468, Percent_Identity=25.4273504273504, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI45551088, Length=382, Percent_Identity=28.0104712041885, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24652942, Length=382, Percent_Identity=28.0104712041885, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24639514, Length=391, Percent_Identity=27.1099744245524, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24582567, Length=399, Percent_Identity=26.8170426065163, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI221329674, Length=391, Percent_Identity=27.1099744245524, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281363702, Length=380, Percent_Identity=27.6315789473684, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45550877, Length=429, Percent_Identity=26.8065268065268, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281365034, Length=418, Percent_Identity=25.8373205741627, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24762620, Length=383, Percent_Identity=26.1096605744125, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI281364136, Length=470, Percent_Identity=24.6808510638298, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24639516, Length=413, Percent_Identity=25.6658595641646, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19921352, Length=420, Percent_Identity=26.1904761904762, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24584353, Length=420, Percent_Identity=26.1904761904762, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281363700, Length=294, Percent_Identity=28.9115646258503, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24655079, Length=297, Percent_Identity=28.6195286195286, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45551183, Length=230, Percent_Identity=29.5652173913043, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24639853, Length=401, Percent_Identity=25.4364089775561, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582569, Length=360, Percent_Identity=24.4444444444444, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24654186, Length=210, Percent_Identity=29.0476190476191, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 47212; Mature: 47212

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MKNNRDSFESKIGFILACIGSAVGMGNIWLFPYRVGQFGGAAFLIPYIIFVVVIGFTGVI
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GEMSFGRAMGTGPVGAFKKALEKRGKKHGDLIGLIPVIGSLGIAIGYSVVVGWILRFTVG
HCCHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
TITGSMIKAPDSGVYFASIAGKLGSLSWHLLALALTFIIMTMGVSKGIEKVNKIMMPAFF
HHCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLFLILAISVGALPGAIEGYRYLLVPKWEFLGEPKTWVFALGQAFFSLSLAGSGTVVYGS
HHHHHHHHHHCCCCCCCCCCEEEEEECHHHCCCCHHHHHHHHHHHHHHEECCCCCEEEHH
YLKKTENIVQSAKYVTLFDTCAAMLAALVIIPSVFAFGMDPTAGPPLMFIIMPNVFKQMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHCC
MGQLSAIIFFLAVLFAGITSLMNLFESPIEALQERFNFSRKASVCIIAMIGAVTGIILED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
ANKLGIWMDVISIYVIPLGALLAGIMFFWICGSKFAREQAQLGNNKEIGSWFEPMTKYAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
CGLTIIVYILGIFYGGIG
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNNRDSFESKIGFILACIGSAVGMGNIWLFPYRVGQFGGAAFLIPYIIFVVVIGFTGVI
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GEMSFGRAMGTGPVGAFKKALEKRGKKHGDLIGLIPVIGSLGIAIGYSVVVGWILRFTVG
HCCHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
TITGSMIKAPDSGVYFASIAGKLGSLSWHLLALALTFIIMTMGVSKGIEKVNKIMMPAFF
HHCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLFLILAISVGALPGAIEGYRYLLVPKWEFLGEPKTWVFALGQAFFSLSLAGSGTVVYGS
HHHHHHHHHHCCCCCCCCCCEEEEEECHHHCCCCHHHHHHHHHHHHHHEECCCCCEEEHH
YLKKTENIVQSAKYVTLFDTCAAMLAALVIIPSVFAFGMDPTAGPPLMFIIMPNVFKQMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHCC
MGQLSAIIFFLAVLFAGITSLMNLFESPIEALQERFNFSRKASVCIIAMIGAVTGIILED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
ANKLGIWMDVISIYVIPLGALLAGIMFFWICGSKFAREQAQLGNNKEIGSWFEPMTKYAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
CGLTIIVYILGIFYGGIG
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]