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The map label for this gene is htpX [H]

Identifier: 28210856

GI number: 28210856

Start: 1243800

End: 1245053

Strand: Direct

Name: htpX [H]

Synonym: CTC01164

Alternate gene names: 28210856

Gene position: 1243800-1245053 (Clockwise)

Preceding gene: 28210852

Following gene: 28210857

Centisome position: 44.43

GC content: 29.35

Gene sequence:

>1254_bases
ATGAAAGACTATTACAACTCAATTTTAAAAAAATCCATATTAATTTTATTTTTTTCTTTTGGATTATTATTTGCAGTAGG
CACAGTAATAGTATGGAAATATGACTTAAGTTTATGGTTTGCCATAGGATTTTCTGTTTCTATAGCATTAATTCAATTTT
TGCTTGGACCTTTCATAATAGAAACGTTTTATGGGATATTATTTGACGATTATGATAGCTATATAAGTGAGGATGTACTA
AGATTTATAGAAAAATCTTGTGATGGATACAATATATCACATCCTAAGATTGGCATAATTGAAGATGGAAATCCAAATGC
TTTTACCTTTGGACATATTCCAAGAAATGCAAGATTAGTTGTTACTACAGGACTTTTAGATATATTAAATGAAGAAGAAC
AAAAGGCTGTAATAGCTCATGAATTAGGACATATAAAACACTATGATTTTATTACTATGATGATAGTATCATTAATTCCT
ATGATATTGTATCAGATATATCTAAGGACTAAAGAGAAAAAAGCCGATGCTAAATACATTGTTGGATTAGGTGCTTATGC
AGCATATTTATTAAGTGGATTTTTGGTTCTAGGTTTTTCGAGAATGAGAGAATATTATTCGGATAATTTTGCAAAAGAGG
TAATGGGAGACGGGGAACATCTAAGAAATGCTTTAGTAAAGATAGCTTATGGAACAGCTAGTAGAGAAAAAGATAAAAAT
CCTAAGGCGTCTTGTATGGCTTTTACAAACAATGTACAAAATGATTCATGGATGCTATCAACTTACAAATTGGATGATAA
TAACAAAATGAAGCTTAATTTAATGAAGTGGGACTTAAAAAATCCATGGGCAAAATGGTACGAAATAAATAGTACTCATC
CATTAACAGGGAAGAGAATAATGGCATTAGACCATGTTGAAATAGAAGATAATGAATCTTCAACCAAGGGACTAGGAAGT
TTTTTATTAGATGCAGCAATTAATATGCTACCTTATATTTTGGTAATAGGTGTATTTGTAAAAAGTTCTCTAAATAAAGA
TACAAGTTTTATTGATTTTATGATAGAAAACCCATTATATATAGTACTTATAGGAGTGAGTATGCTTTTAAGATATTATT
ATTCCTATGGAAGAGGCTATGAACAAAGAACTATAGAAGAACTTTTATCAAGAGATGATGCATCTCCTGTAAAGGATTCC
TACAATATTAAAAGGAAAAGTTATAGGAAAGGGTATACCAGGTTTATTTTATAG

Upstream 100 bases:

>100_bases
AATTAATAGTAAAAGTATGGTAATAGAGGTTAATATAATAAATTTTAATAAAACTATTAAAGAGGGTTTAGAATAATATA
TATAAAGGGGAGTATAAAAT

Downstream 100 bases:

>100_bases
TGAAGATTTAATGCTAGATGATGGAACAGGAATAATGTTAGTAGATTATAGACAACCACTTAAAATATTTCAATGGGCAT
TTGCATTATTTCAAGTAGAT

Product: protease htpX-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MKDYYNSILKKSILILFFSFGLLFAVGTVIVWKYDLSLWFAIGFSVSIALIQFLLGPFIIETFYGILFDDYDSYISEDVL
RFIEKSCDGYNISHPKIGIIEDGNPNAFTFGHIPRNARLVVTTGLLDILNEEEQKAVIAHELGHIKHYDFITMMIVSLIP
MILYQIYLRTKEKKADAKYIVGLGAYAAYLLSGFLVLGFSRMREYYSDNFAKEVMGDGEHLRNALVKIAYGTASREKDKN
PKASCMAFTNNVQNDSWMLSTYKLDDNNKMKLNLMKWDLKNPWAKWYEINSTHPLTGKRIMALDHVEIEDNESSTKGLGS
FLLDAAINMLPYILVIGVFVKSSLNKDTSFIDFMIENPLYIVLIGVSMLLRYYYSYGRGYEQRTIEELLSRDDASPVKDS
YNIKRKSYRKGYTRFIL

Sequences:

>Translated_417_residues
MKDYYNSILKKSILILFFSFGLLFAVGTVIVWKYDLSLWFAIGFSVSIALIQFLLGPFIIETFYGILFDDYDSYISEDVL
RFIEKSCDGYNISHPKIGIIEDGNPNAFTFGHIPRNARLVVTTGLLDILNEEEQKAVIAHELGHIKHYDFITMMIVSLIP
MILYQIYLRTKEKKADAKYIVGLGAYAAYLLSGFLVLGFSRMREYYSDNFAKEVMGDGEHLRNALVKIAYGTASREKDKN
PKASCMAFTNNVQNDSWMLSTYKLDDNNKMKLNLMKWDLKNPWAKWYEINSTHPLTGKRIMALDHVEIEDNESSTKGLGS
FLLDAAINMLPYILVIGVFVKSSLNKDTSFIDFMIENPLYIVLIGVSMLLRYYYSYGRGYEQRTIEELLSRDDASPVKDS
YNIKRKSYRKGYTRFIL
>Mature_417_residues
MKDYYNSILKKSILILFFSFGLLFAVGTVIVWKYDLSLWFAIGFSVSIALIQFLLGPFIIETFYGILFDDYDSYISEDVL
RFIEKSCDGYNISHPKIGIIEDGNPNAFTFGHIPRNARLVVTTGLLDILNEEEQKAVIAHELGHIKHYDFITMMIVSLIP
MILYQIYLRTKEKKADAKYIVGLGAYAAYLLSGFLVLGFSRMREYYSDNFAKEVMGDGEHLRNALVKIAYGTASREKDKN
PKASCMAFTNNVQNDSWMLSTYKLDDNNKMKLNLMKWDLKNPWAKWYEINSTHPLTGKRIMALDHVEIEDNESSTKGLGS
FLLDAAINMLPYILVIGVFVKSSLNKDTSFIDFMIENPLYIVLIGVSMLLRYYYSYGRGYEQRTIEELLSRDDASPVKDS
YNIKRKSYRKGYTRFIL

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 47987; Mature: 47987

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDYYNSILKKSILILFFSFGLLFAVGTVIVWKYDLSLWFAIGFSVSIALIQFLLGPFII
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ETFYGILFDDYDSYISEDVLRFIEKSCDGYNISHPKIGIIEDGNPNAFTFGHIPRNARLV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCEEE
VTTGLLDILNEEEQKAVIAHELGHIKHYDFITMMIVSLIPMILYQIYLRTKEKKADAKYI
EEEHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VGLGAYAAYLLSGFLVLGFSRMREYYSDNFAKEVMGDGEHLRNALVKIAYGTASREKDKN
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCC
PKASCMAFTNNVQNDSWMLSTYKLDDNNKMKLNLMKWDLKNPWAKWYEINSTHPLTGKRI
CCHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCHHHEECCCCCCCCCCEE
MALDHVEIEDNESSTKGLGSFLLDAAINMLPYILVIGVFVKSSLNKDTSFIDFMIENPLY
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCE
IVLIGVSMLLRYYYSYGRGYEQRTIEELLSRDDASPVKDSYNIKRKSYRKGYTRFIL
EHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHCC
>Mature Secondary Structure
MKDYYNSILKKSILILFFSFGLLFAVGTVIVWKYDLSLWFAIGFSVSIALIQFLLGPFII
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ETFYGILFDDYDSYISEDVLRFIEKSCDGYNISHPKIGIIEDGNPNAFTFGHIPRNARLV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCEEE
VTTGLLDILNEEEQKAVIAHELGHIKHYDFITMMIVSLIPMILYQIYLRTKEKKADAKYI
EEEHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VGLGAYAAYLLSGFLVLGFSRMREYYSDNFAKEVMGDGEHLRNALVKIAYGTASREKDKN
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCC
PKASCMAFTNNVQNDSWMLSTYKLDDNNKMKLNLMKWDLKNPWAKWYEINSTHPLTGKRI
CCHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEEEEECCCCCCHHHEECCCCCCCCCCEE
MALDHVEIEDNESSTKGLGSFLLDAAINMLPYILVIGVFVKSSLNKDTSFIDFMIENPLY
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCE
IVLIGVSMLLRYYYSYGRGYEQRTIEELLSRDDASPVKDSYNIKRKSYRKGYTRFIL
EHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]