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The map label for this gene is 28210735

Identifier: 28210735

GI number: 28210735

Start: 1101063

End: 1101674

Strand: Direct

Name: 28210735

Synonym: CTC01030

Alternate gene names: NA

Gene position: 1101063-1101674 (Clockwise)

Preceding gene: 28210734

Following gene: 28210736

Centisome position: 39.33

GC content: 31.05

Gene sequence:

>612_bases
ATGAAAATTCAAAGAAAGTTTTATGAAAAAAGTGCCCTGCAAGTTGCTAAATACCTTTTAGGAAAGATTCTTGTTAATGA
AGTAGAAGGGATAACCCTAAAGGGAAAGATAGTGGAAACGGAAGCTTATATTGGAGCTATTGATAAAGCAAGTCATGCCT
ATGGTGGGAAAAAAACAGAAAGAGTAATGCCTTTATATGGAAAGCCAGGCACTGCCTATGTTTACCTTATATATGGAATG
TATCATTGTTTTAATGTGATTACAAAAGTAGAAGGAGAAGCAGAAGGAGTTCTTATAAGGGCAATAGAACCTTTAGAGGG
AATTGAAAAAATGGCATATTTAAGATACAAGAAGCCTATAAGTGAAATAAGTAAAACACAATTTAAAAATTTAACCACAG
GGCCAGGAAAATTATGTATAGCCTTAAATATAGATAAAAGTAATAATAAGCAAGATCTTTGCAATGAAGGAACTCTTTAC
ATAGAACATAATGATAAAGAAAAATTTAATATAGTGGAAAGCAAAAGAATAGGTATAGAATACGCGGAAGAAGCTAAAGA
TTTTTTATGGAGATTTTACATAGAAGATAATCCTTGGATTTCCAAAAAATAA

Upstream 100 bases:

>100_bases
GGAATAAATTACTTTAAATAATCTAAAACTACCTCTAAATAGGAATTTAGTTTAAATTATTTATATAATTAGAGTTAAAG
TATGCTTTTGGAGGTATCCT

Downstream 100 bases:

>100_bases
AATTTGTATACTTAGTAGCACAATTATTGTGCTACATTTTCTTTATACAACATAAAATAAAAATTTTGCGAAGCGAAACT
TTTATTAAATTATTTACTAT

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKIQRKFYEKSALQVAKYLLGKILVNEVEGITLKGKIVETEAYIGAIDKASHAYGGKKTERVMPLYGKPGTAYVYLIYGM
YHCFNVITKVEGEAEGVLIRAIEPLEGIEKMAYLRYKKPISEISKTQFKNLTTGPGKLCIALNIDKSNNKQDLCNEGTLY
IEHNDKEKFNIVESKRIGIEYAEEAKDFLWRFYIEDNPWISKK

Sequences:

>Translated_203_residues
MKIQRKFYEKSALQVAKYLLGKILVNEVEGITLKGKIVETEAYIGAIDKASHAYGGKKTERVMPLYGKPGTAYVYLIYGM
YHCFNVITKVEGEAEGVLIRAIEPLEGIEKMAYLRYKKPISEISKTQFKNLTTGPGKLCIALNIDKSNNKQDLCNEGTLY
IEHNDKEKFNIVESKRIGIEYAEEAKDFLWRFYIEDNPWISKK
>Mature_203_residues
MKIQRKFYEKSALQVAKYLLGKILVNEVEGITLKGKIVETEAYIGAIDKASHAYGGKKTERVMPLYGKPGTAYVYLIYGM
YHCFNVITKVEGEAEGVLIRAIEPLEGIEKMAYLRYKKPISEISKTQFKNLTTGPGKLCIALNIDKSNNKQDLCNEGTLY
IEHNDKEKFNIVESKRIGIEYAEEAKDFLWRFYIEDNPWISKK

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=203, Percent_Identity=39.4088669950739, Blast_Score=148, Evalue=4e-36,
Organism=Homo sapiens, GI62632765, Length=203, Percent_Identity=39.4088669950739, Blast_Score=148, Evalue=4e-36,
Organism=Homo sapiens, GI62632771, Length=203, Percent_Identity=39.4088669950739, Blast_Score=147, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_CLOTE (Q896H4)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781679.1
- ProteinModelPortal:   Q896H4
- SMR:   Q896H4
- GeneID:   1059798
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC01030
- NMPDR:   fig|212717.1.peg.901
- HOGENOM:   HBG664239
- OMA:   EHISSQY
- ProtClustDB:   PRK00802
- BioCyc:   CTET212717:CTC_01030-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 23246; Mature: 23246

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIQRKFYEKSALQVAKYLLGKILVNEVEGITLKGKIVETEAYIGAIDKASHAYGGKKTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECHHHHHHHHCCHHHCCCCCCC
RVMPLYGKPGTAYVYLIYGMYHCFNVITKVEGEAEGVLIRAIEPLEGIEKMAYLRYKKPI
EEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCH
SEISKTQFKNLTTGPGKLCIALNIDKSNNKQDLCNEGTLYIEHNDKEKFNIVESKRIGIE
HHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHCCCCEEEEEECCCCCEEEEHHHHCCCC
YAEEAKDFLWRFYIEDNPWISKK
HHHHHHHEEEEEEECCCCCCCCC
>Mature Secondary Structure
MKIQRKFYEKSALQVAKYLLGKILVNEVEGITLKGKIVETEAYIGAIDKASHAYGGKKTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECHHHHHHHHCCHHHCCCCCCC
RVMPLYGKPGTAYVYLIYGMYHCFNVITKVEGEAEGVLIRAIEPLEGIEKMAYLRYKKPI
EEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCH
SEISKTQFKNLTTGPGKLCIALNIDKSNNKQDLCNEGTLYIEHNDKEKFNIVESKRIGIE
HHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHCCCCEEEEEECCCCCEEEEHHHHCCCC
YAEEAKDFLWRFYIEDNPWISKK
HHHHHHHEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129