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The map label for this gene is etfA [H]

Identifier: 28210682

GI number: 28210682

Start: 1041206

End: 1042405

Strand: Direct

Name: etfA [H]

Synonym: CTC00974

Alternate gene names: 28210682

Gene position: 1041206-1042405 (Clockwise)

Preceding gene: 28210681

Following gene: 28210683

Centisome position: 37.2

GC content: 30.42

Gene sequence:

>1200_bases
ATGGGAAAATTATATATAAATCAAGATAAATTAAATGAAAAAAATATAGAAGAGTTAGTAAAGATATGTCCTTTTAATGC
CATAGAAGAAGCAGATGGAAAATTATCAATAAATGCAGGCTGCAAAATGTGTAAATTATGCGTAAAAAAAGGACCTAAAG
GGGTTATTGAATTTATAGAAGAAACTGTTGAAAAAATAGATAAGAGTAAGTGGAACGGTATAGCTGTTTATGTAGATCAT
ACAGAGGGAAGAATACATCCTGTAACTTATGAACTTATAGGCAAAGCAAAAGAACTTGCAGGCAAAATAAATCATCCAGT
ATATGCAGTATTTATAGGAAGTAGCATAGAAGATAAAGCAGAAGAATTACTTCACTATGGTGTTGATAAGGTTTTTGTAT
ATGATGAAAAAGAACTTGAAGATTTTAGAATAGAACCTTATACAGCAGCTTTTGAAGATTTTATAAACAAAGTAAAACCA
TGTTCTATTTTAGTAGGAGCTACTACTGTAGGAAGATCACTTGCACCAAGAGTTGCAGCAAGATTTAGAACAGGGCTGAC
AGCAGATTGTACTGTTTTAGATATGAAAGAAAATACTGACTTAGTTCAGATAAGACCAGCATTTGGTGGAAATATAATGG
CACAAATAATTACTCCCAATCAAAGACCACAATTCTGTACTGTAAGATATAAGATAATGACTACAGCAGAAAGACAAGAA
GAAAAAAGTGGAGAAATTATAAGAGGTAAAGTAGATAGTGAAAAACTTAAATCCAATATAAAAGTATTAAATACAGTAAA
GAAAGAAAAAGAAGAAGATATATCTGAAGCAGATGTTATAGTTGTAGCTGGAAGAGGAATAAAATCTGAAAAAGATATGG
AAATGATTAATGAATTAGCTAACTGTTTAGATGCACAAGTTGCAGCGACAAGACCATTAATTGAAGCAGGATGGATTGGA
CCTAAAAAACAAATAGGATTAAGTGGAAGAACTGTAAAACCTAAATTAATAATAACTTGTGGAGTATCAGGTGCAGTACA
ATTTATAGCTGGTATGAATAATTCAGATCATATTTTTGCTATAAATGAAGATCCTAATGCAGATATTTTTAATGTAGCTC
ACTACGCCATAGTAGGGGATATATATCAAGTAATACCTCAAATAATTAGCGATATAAAAAATCATAAGAAAATAGTATAA

Upstream 100 bases:

>100_bases
GAAATGTGGGAAGGCAATGGAATAGAATTAGGCGATAGAGTTTTTCAAGAATTAAAGAAATTAAAATATGTTTAAATAAA
GGATTTTTGGAGGGAGATTT

Downstream 100 bases:

>100_bases
ATTTAGGAGGTTTATTTTATGAAAGTAAATGAAGCTTATAAGACAATAGATAAAAAGGATATAGAATATTTCATTTCAAT
TCTAGGGAAAAATAGGGTTT

Product: electron transfer flavoprotein alpha-subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MGKLYINQDKLNEKNIEELVKICPFNAIEEADGKLSINAGCKMCKLCVKKGPKGVIEFIEETVEKIDKSKWNGIAVYVDH
TEGRIHPVTYELIGKAKELAGKINHPVYAVFIGSSIEDKAEELLHYGVDKVFVYDEKELEDFRIEPYTAAFEDFINKVKP
CSILVGATTVGRSLAPRVAARFRTGLTADCTVLDMKENTDLVQIRPAFGGNIMAQIITPNQRPQFCTVRYKIMTTAERQE
EKSGEIIRGKVDSEKLKSNIKVLNTVKKEKEEDISEADVIVVAGRGIKSEKDMEMINELANCLDAQVAATRPLIEAGWIG
PKKQIGLSGRTVKPKLIITCGVSGAVQFIAGMNNSDHIFAINEDPNADIFNVAHYAIVGDIYQVIPQIISDIKNHKKIV

Sequences:

>Translated_399_residues
MGKLYINQDKLNEKNIEELVKICPFNAIEEADGKLSINAGCKMCKLCVKKGPKGVIEFIEETVEKIDKSKWNGIAVYVDH
TEGRIHPVTYELIGKAKELAGKINHPVYAVFIGSSIEDKAEELLHYGVDKVFVYDEKELEDFRIEPYTAAFEDFINKVKP
CSILVGATTVGRSLAPRVAARFRTGLTADCTVLDMKENTDLVQIRPAFGGNIMAQIITPNQRPQFCTVRYKIMTTAERQE
EKSGEIIRGKVDSEKLKSNIKVLNTVKKEKEEDISEADVIVVAGRGIKSEKDMEMINELANCLDAQVAATRPLIEAGWIG
PKKQIGLSGRTVKPKLIITCGVSGAVQFIAGMNNSDHIFAINEDPNADIFNVAHYAIVGDIYQVIPQIISDIKNHKKIV
>Mature_398_residues
GKLYINQDKLNEKNIEELVKICPFNAIEEADGKLSINAGCKMCKLCVKKGPKGVIEFIEETVEKIDKSKWNGIAVYVDHT
EGRIHPVTYELIGKAKELAGKINHPVYAVFIGSSIEDKAEELLHYGVDKVFVYDEKELEDFRIEPYTAAFEDFINKVKPC
SILVGATTVGRSLAPRVAARFRTGLTADCTVLDMKENTDLVQIRPAFGGNIMAQIITPNQRPQFCTVRYKIMTTAERQEE
KSGEIIRGKVDSEKLKSNIKVLNTVKKEKEEDISEADVIVVAGRGIKSEKDMEMINELANCLDAQVAATRPLIEAGWIGP
KKQIGLSGRTVKPKLIITCGVSGAVQFIAGMNNSDHIFAINEDPNADIFNVAHYAIVGDIYQVIPQIISDIKNHKKIV

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=341, Percent_Identity=28.7390029325513, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI189181759, Length=283, Percent_Identity=30.7420494699647, Blast_Score=126, Evalue=3e-29,
Organism=Escherichia coli, GI1787990, Length=334, Percent_Identity=29.3413173652695, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786226, Length=306, Percent_Identity=25.4901960784314, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082157, Length=265, Percent_Identity=26.4150943396226, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17506929, Length=335, Percent_Identity=28.3582089552239, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6325261, Length=301, Percent_Identity=29.5681063122924, Blast_Score=132, Evalue=8e-32,
Organism=Drosophila melanogaster, GI17136898, Length=315, Percent_Identity=29.8412698412698, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24652801, Length=315, Percent_Identity=29.8412698412698, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 44281; Mature: 44150

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLYINQDKLNEKNIEELVKICPFNAIEEADGKLSINAGCKMCKLCVKKGPKGVIEFIE
CCCEEECCCCCCCCCHHHHHHHCCCCCHHCCCCEEEECCCHHHHHHHHHCCCHHHHHHHH
ETVEKIDKSKWNGIAVYVDHTEGRIHPVTYELIGKAKELAGKINHPVYAVFIGSSIEDKA
HHHHHHHCCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
EELLHYGVDKVFVYDEKELEDFRIEPYTAAFEDFINKVKPCSILVGATTVGRSLAPRVAA
HHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHHCHHHHHHHHH
RFRTGLTADCTVLDMKENTDLVQIRPAFGGNIMAQIITPNQRPQFCTVRYKIMTTAERQE
HHHCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEEEECHHHHH
EKSGEIIRGKVDSEKLKSNIKVLNTVKKEKEEDISEADVIVVAGRGIKSEKDMEMINELA
HHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHH
NCLDAQVAATRPLIEAGWIGPKKQIGLSGRTVKPKLIITCGVSGAVQFIAGMNNSDHIFA
HHHHHHHHHCCCCHHHCCCCCCHHCCCCCCEECCEEEEEECCHHHHHHHHCCCCCCEEEE
INEDPNADIFNVAHYAIVGDIYQVIPQIISDIKNHKKIV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GKLYINQDKLNEKNIEELVKICPFNAIEEADGKLSINAGCKMCKLCVKKGPKGVIEFIE
CCEEECCCCCCCCCHHHHHHHCCCCCHHCCCCEEEECCCHHHHHHHHHCCCHHHHHHHH
ETVEKIDKSKWNGIAVYVDHTEGRIHPVTYELIGKAKELAGKINHPVYAVFIGSSIEDKA
HHHHHHHCCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
EELLHYGVDKVFVYDEKELEDFRIEPYTAAFEDFINKVKPCSILVGATTVGRSLAPRVAA
HHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHHCHHHHHHHHH
RFRTGLTADCTVLDMKENTDLVQIRPAFGGNIMAQIITPNQRPQFCTVRYKIMTTAERQE
HHHCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEEEEEEECHHHHH
EKSGEIIRGKVDSEKLKSNIKVLNTVKKEKEEDISEADVIVVAGRGIKSEKDMEMINELA
HHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHH
NCLDAQVAATRPLIEAGWIGPKKQIGLSGRTVKPKLIITCGVSGAVQFIAGMNNSDHIFA
HHHHHHHHHCCCCHHHCCCCCCHHCCCCCCEECCEEEEEECCHHHHHHHHCCCCCCEEEE
INEDPNADIFNVAHYAIVGDIYQVIPQIISDIKNHKKIV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA