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The map label for this gene is argS

Identifier: 28210674

GI number: 28210674

Start: 1031452

End: 1033143

Strand: Direct

Name: argS

Synonym: CTC00966

Alternate gene names: 28210674

Gene position: 1031452-1033143 (Clockwise)

Preceding gene: 28210673

Following gene: 28210675

Centisome position: 36.85

GC content: 28.84

Gene sequence:

>1692_bases
ATGAATTATAAAGAGTTAATAAGTGAAAGATTAAGTTCCATTATAGAATTGCCTATAGAAGATATAGAAAAACTTATTGA
AATACCACCAAAACCAGAAATGGGGGATTTTGCTTTTCCATGCTTTCAGTTAGCTAAAACATTTAGAAAAGCACCTAATA
TGATTGCAGAGGAATTAAAGGATAAATTTGATAAAAGTAATTTTGAAAAGGTTGAAAACTTAGGGCCCTATTTGAATTTT
TTTGTGGATAAATCTATATTTAGTAAAAATGTAATAGAAAAAATATTAGAAGAGAAAGATAAATATGGAGCTTCAAATGA
AGGAAAAGGAAGAAAAGCATTAATAGAATATTCTTCTCCTAATATTGCAAAGCCTTTCCATGTAGGACATTTATTTAGTA
CTGCCATTGGAAATGCTTTATATAAAATATTTACCTTTGAAGGATATGATTGTGAAAGACTAAATCATTTAGGAGATTGG
GGAACACAATTTGGAAAACTAATAGCCGCTTACAAAAGATGGGTAGATGAAGAAGCCTTAGAAAAAGAACCTATAAAAGA
GCTTTTAAGAATATATGTTAAATTCCATGATGAAGCAGAAAAAGATCCTGCCCTAGAAGAAGAAGGAAGACTACATTTTA
AAAGATTGGAAGATGGAGAAGAAGAGGAAGTTAAGCTTTGGAAGAAATTTAGAGAACTAAGTCTAAAGGAATTTGAAAAA
GTGTATCATATGTTAAATGTAGAGTTTGATTCCTATGCAGGAGAAAGTTTCTATGGCGACAAAATGGATGCCGTAGTAGA
AGAAATAGATGAAAAAGGATTACTTGTAGAAAGTAATGGTGCAAAGGTTGTAATGTTAGAGGACTACAATATGCCACCTT
GTATAATTAAAAAATCAGATGGAGCAACTATTTATGCTACTAGGGATTTAGCTACAGCTATATATAGAAAAAAGACATAT
GATTTTTATAAAAGTATATATGTAGTTGGATTAGAACAATCCTTACACTTTAAACAAGTATTTACAACATTAAAATTAAT
GGGACATGATTGGGCAGATGATTGTACTCATATAGGATTTGGTTTAGTAAGATTTACAGATAGAAAACTATCTACTAGAA
AAGGTGAGGTTATATTCCTTGAAGATCTTTTAAAAGAATCTGTAGATAAAACATTAGAAATAATAAATGAAAAGAATTCA
GAACTAGAAAATAAAGAAGAAACAGCTAAAAAAATAGGAATAGGTGCAGTTATATTTACATATCTTAAAAACAACAGAGA
AAGGGATATAGTATTTAGTTGGGATGAAATGTTAAGCTTTGATGGGGAAACGGGACCTTATGTTCAATATAGCTATGCTA
GAGGAAAAAGCATATTGAGAAAATCAGGAGAAATACAAGGAGATGTTGATTATAGTAAATTAAATTCTAAAGAAGAATTT
GAACTTGTAAAAACTTTAGAAGGTTTTAATAAATCCATACTTCAAGCAATAGAAAAATTAGAACCATCTATTGTAACAAG
ATATGTAATAGAAGTTGCTAAAGCTTTTAACAAATTCTATAACCACAATAGTATTTTAAATGCAGAAGATGAAGAGATAA
AGAAAGCTAGAATAAAACTTGTTGAATCAACTTGTCAAGTTATAAAAAATGCTCTTAACTTATTAGGAATAGAAGTAGTA
GAAAAAATGTAA

Upstream 100 bases:

>100_bases
TATGTCAATTAGAGTGGTACCGCGGATAAAACCGTCTCTTTATAATGTTAAAGAGATGGTTTTTTTATATGAAAAATAAT
AAATACAGGAGGGTTATAAA

Downstream 100 bases:

>100_bases
AATAATTATTAAATAGCCTATATAAATAGATTTTTGTATAAATCTATCTATGTGGGCTGTTTTTATTGTATAATAGTATA
TGGGCAACATTAGAGGAGTG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MNYKELISERLSSIIELPIEDIEKLIEIPPKPEMGDFAFPCFQLAKTFRKAPNMIAEELKDKFDKSNFEKVENLGPYLNF
FVDKSIFSKNVIEKILEEKDKYGASNEGKGRKALIEYSSPNIAKPFHVGHLFSTAIGNALYKIFTFEGYDCERLNHLGDW
GTQFGKLIAAYKRWVDEEALEKEPIKELLRIYVKFHDEAEKDPALEEEGRLHFKRLEDGEEEEVKLWKKFRELSLKEFEK
VYHMLNVEFDSYAGESFYGDKMDAVVEEIDEKGLLVESNGAKVVMLEDYNMPPCIIKKSDGATIYATRDLATAIYRKKTY
DFYKSIYVVGLEQSLHFKQVFTTLKLMGHDWADDCTHIGFGLVRFTDRKLSTRKGEVIFLEDLLKESVDKTLEIINEKNS
ELENKEETAKKIGIGAVIFTYLKNNRERDIVFSWDEMLSFDGETGPYVQYSYARGKSILRKSGEIQGDVDYSKLNSKEEF
ELVKTLEGFNKSILQAIEKLEPSIVTRYVIEVAKAFNKFYNHNSILNAEDEEIKKARIKLVESTCQVIKNALNLLGIEVV
EKM

Sequences:

>Translated_563_residues
MNYKELISERLSSIIELPIEDIEKLIEIPPKPEMGDFAFPCFQLAKTFRKAPNMIAEELKDKFDKSNFEKVENLGPYLNF
FVDKSIFSKNVIEKILEEKDKYGASNEGKGRKALIEYSSPNIAKPFHVGHLFSTAIGNALYKIFTFEGYDCERLNHLGDW
GTQFGKLIAAYKRWVDEEALEKEPIKELLRIYVKFHDEAEKDPALEEEGRLHFKRLEDGEEEEVKLWKKFRELSLKEFEK
VYHMLNVEFDSYAGESFYGDKMDAVVEEIDEKGLLVESNGAKVVMLEDYNMPPCIIKKSDGATIYATRDLATAIYRKKTY
DFYKSIYVVGLEQSLHFKQVFTTLKLMGHDWADDCTHIGFGLVRFTDRKLSTRKGEVIFLEDLLKESVDKTLEIINEKNS
ELENKEETAKKIGIGAVIFTYLKNNRERDIVFSWDEMLSFDGETGPYVQYSYARGKSILRKSGEIQGDVDYSKLNSKEEF
ELVKTLEGFNKSILQAIEKLEPSIVTRYVIEVAKAFNKFYNHNSILNAEDEEIKKARIKLVESTCQVIKNALNLLGIEVV
EKM
>Mature_563_residues
MNYKELISERLSSIIELPIEDIEKLIEIPPKPEMGDFAFPCFQLAKTFRKAPNMIAEELKDKFDKSNFEKVENLGPYLNF
FVDKSIFSKNVIEKILEEKDKYGASNEGKGRKALIEYSSPNIAKPFHVGHLFSTAIGNALYKIFTFEGYDCERLNHLGDW
GTQFGKLIAAYKRWVDEEALEKEPIKELLRIYVKFHDEAEKDPALEEEGRLHFKRLEDGEEEEVKLWKKFRELSLKEFEK
VYHMLNVEFDSYAGESFYGDKMDAVVEEIDEKGLLVESNGAKVVMLEDYNMPPCIIKKSDGATIYATRDLATAIYRKKTY
DFYKSIYVVGLEQSLHFKQVFTTLKLMGHDWADDCTHIGFGLVRFTDRKLSTRKGEVIFLEDLLKESVDKTLEIINEKNS
ELENKEETAKKIGIGAVIFTYLKNNRERDIVFSWDEMLSFDGETGPYVQYSYARGKSILRKSGEIQGDVDYSKLNSKEEF
ELVKTLEGFNKSILQAIEKLEPSIVTRYVIEVAKAFNKFYNHNSILNAEDEEIKKARIKLVESTCQVIKNALNLLGIEVV
EKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=580, Percent_Identity=33.448275862069, Blast_Score=326, Evalue=5e-89,
Organism=Homo sapiens, GI15149476, Length=600, Percent_Identity=30.8333333333333, Blast_Score=235, Evalue=9e-62,
Organism=Escherichia coli, GI1788184, Length=586, Percent_Identity=32.9351535836177, Blast_Score=303, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI71985061, Length=602, Percent_Identity=32.0598006644518, Blast_Score=235, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI71985068, Length=570, Percent_Identity=32.1052631578947, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17532153, Length=494, Percent_Identity=26.5182186234818, Blast_Score=159, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6320548, Length=578, Percent_Identity=36.8512110726644, Blast_Score=364, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6321883, Length=511, Percent_Identity=36.986301369863, Blast_Score=357, Evalue=2e-99,
Organism=Drosophila melanogaster, GI28571570, Length=539, Percent_Identity=31.1688311688312, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI18859963, Length=546, Percent_Identity=31.1355311355311, Blast_Score=226, Evalue=4e-59,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_CLOTE (Q896N5)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781618.1
- ProteinModelPortal:   Q896N5
- SMR:   Q896N5
- GeneID:   1059771
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC00966
- NMPDR:   fig|212717.1.peg.840
- HOGENOM:   HBG695395
- OMA:   AYKKWGN
- PhylomeDB:   Q896N5
- ProtClustDB:   PRK01611
- BioCyc:   CTET212717:CTC_00966-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65076; Mature: 65076

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKELISERLSSIIELPIEDIEKLIEIPPKPEMGDFAFPCFQLAKTFRKAPNMIAEELK
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHH
DKFDKSNFEKVENLGPYLNFFVDKSIFSKNVIEKILEEKDKYGASNEGKGRKALIEYSSP
HHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
NIAKPFHVGHLFSTAIGNALYKIFTFEGYDCERLNHLGDWGTQFGKLIAAYKRWVDEEAL
CCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
EKEPIKELLRIYVKFHDEAEKDPALEEEGRLHFKRLEDGEEEEVKLWKKFRELSLKEFEK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCHHHHHH
VYHMLNVEFDSYAGESFYGDKMDAVVEEIDEKGLLVESNGAKVVMLEDYNMPPCIIKKSD
HHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCEEEECCC
GATIYATRDLATAIYRKKTYDFYKSIYVVGLEQSLHFKQVFTTLKLMGHDWADDCTHIGF
CCEEEEHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GLVRFTDRKLSTRKGEVIFLEDLLKESVDKTLEIINEKNSELENKEETAKKIGIGAVIFT
HHHHEECCHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHH
YLKNNRERDIVFSWDEMLSFDGETGPYVQYSYARGKSILRKSGEIQGDVDYSKLNSKEEF
HHHCCCCCCEEEEHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCHHHCCCHHHH
ELVKTLEGFNKSILQAIEKLEPSIVTRYVIEVAKAFNKFYNHNSILNAEDEEIKKARIKL
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VESTCQVIKNALNLLGIEVVEKM
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYKELISERLSSIIELPIEDIEKLIEIPPKPEMGDFAFPCFQLAKTFRKAPNMIAEELK
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHH
DKFDKSNFEKVENLGPYLNFFVDKSIFSKNVIEKILEEKDKYGASNEGKGRKALIEYSSP
HHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
NIAKPFHVGHLFSTAIGNALYKIFTFEGYDCERLNHLGDWGTQFGKLIAAYKRWVDEEAL
CCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
EKEPIKELLRIYVKFHDEAEKDPALEEEGRLHFKRLEDGEEEEVKLWKKFRELSLKEFEK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCHHHHHH
VYHMLNVEFDSYAGESFYGDKMDAVVEEIDEKGLLVESNGAKVVMLEDYNMPPCIIKKSD
HHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCEEEECCC
GATIYATRDLATAIYRKKTYDFYKSIYVVGLEQSLHFKQVFTTLKLMGHDWADDCTHIGF
CCEEEEHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GLVRFTDRKLSTRKGEVIFLEDLLKESVDKTLEIINEKNSELENKEETAKKIGIGAVIFT
HHHHEECCHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHH
YLKNNRERDIVFSWDEMLSFDGETGPYVQYSYARGKSILRKSGEIQGDVDYSKLNSKEEF
HHHCCCCCCEEEEHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCHHHCCCHHHH
ELVKTLEGFNKSILQAIEKLEPSIVTRYVIEVAKAFNKFYNHNSILNAEDEEIKKARIKL
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VESTCQVIKNALNLLGIEVVEKM
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129