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The map label for this gene is fecD [H]

Identifier: 28210670

GI number: 28210670

Start: 1025911

End: 1027044

Strand: Direct

Name: fecD [H]

Synonym: CTC00961

Alternate gene names: 28210670

Gene position: 1025911-1027044 (Clockwise)

Preceding gene: 28210669

Following gene: 28210671

Centisome position: 36.65

GC content: 31.48

Gene sequence:

>1134_bases
ATGCTAAGGAACTATATCCAGAGCTATTTAAATAATATGAAGGATATATTAAAATCAAAATCCACTAGTAGAGGAAAGAA
AAATTTAGAACCAGTGAAAGTAGCTAATTCAATAGTTGTAATAGGCCTAATTATACTTTTAATAATATCAATAATTTGTG
CTGTAGGTATTGGTTCAGTAAAAATACCTGTAGCAGATGTGTATAGGATTATTTTATATAAGATATTCGGCATTAAAGGA
CTAGAGTCTGCTATTCAAGGACAATTTGTTGATATCATATGGCAAATAAGATTGCCAAGAGTTTTGCTTGGAGTAGTTGT
AGGTATGGGGTTAGCTCTAGGAGGAGTTGTAATGCAGGCAACGGTTCAAAATCCTTTAGCTGATCCATATATATTGGGAA
TTTCCTCTGGTGCTATTTTAGGAGCTACGTTTTTTATATTAGTAGGATCTAATATTTTAACAGGGACATTTCAAAGCGTT
GGAATAGCGTTTTGGGCATTTATTGGAGCATTAATGTCATCTATAATGGTTTTTAAACTATCTAGTATAGGGGGACGAAT
TACTTCAACAAAATTAGTATTATCAGGTATGGTAGTTAGTATCATATGCTCAGCTTTTTCAAGTTTGATGGTATATCTTA
CTAATGATAACAATGCTGTACGTTCTATTTCAGAATGGGCTATGGGTAGTTTAACAGGGGGGAAATGGAGTAATTTGTGG
TTTCCTACAATAATAACCTTTATATTAATTGCTTTTTTCCTATGTCAATATCGCATTATGAATACTATGCTTTTAGGTGA
TGAAGCGGCTATAACGTTAGGTATAGATTTAAGTAAATATAGAAAATTATATATGATTATGGTATCTATATTAACTGGAG
TATTAGTATCAAGCTGTGGAATTATAGGTTTTATAGGATTGGTAATTCCACATATAACTAGGAGTTTAGTTGGGTCAAAT
CATAAAAATAATTTGCCTGTGGCTATACTTATTGGAGGTATCTTTCTTGTGTGGGCAGATGTATTAGCACGTATTATTCT
TAAAAATATGGAGATGCCAATAGGTATTATAACTTCGGTAATAGGGGCTCCATTTTTTATATATATTATATTAAAACGTG
CATATAGTTTTTAA

Upstream 100 bases:

>100_bases
TTAGCTAATGTAAATGCTATTAAGAATAAAAAAATAATTATCACTGGTTTAGCAGAAACATGGGCCGGCGGAGTTCGCAC
TGTTGATGCAGTAGAACGTT

Downstream 100 bases:

>100_bases
GAGGGGTAACTGAATATGAAGTTAAGTGTTGAAAATATAAATGTACAATTAGGTAATAAAAAAATAGTTCATAATGCGTG
TATTGAAGTTAATAAAGGTG

Product: iron(III) dicitrate transport system permease protein fecD

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MLRNYIQSYLNNMKDILKSKSTSRGKKNLEPVKVANSIVVIGLIILLIISIICAVGIGSVKIPVADVYRIILYKIFGIKG
LESAIQGQFVDIIWQIRLPRVLLGVVVGMGLALGGVVMQATVQNPLADPYILGISSGAILGATFFILVGSNILTGTFQSV
GIAFWAFIGALMSSIMVFKLSSIGGRITSTKLVLSGMVVSIICSAFSSLMVYLTNDNNAVRSISEWAMGSLTGGKWSNLW
FPTIITFILIAFFLCQYRIMNTMLLGDEAAITLGIDLSKYRKLYMIMVSILTGVLVSSCGIIGFIGLVIPHITRSLVGSN
HKNNLPVAILIGGIFLVWADVLARIILKNMEMPIGIITSVIGAPFFIYIILKRAYSF

Sequences:

>Translated_377_residues
MLRNYIQSYLNNMKDILKSKSTSRGKKNLEPVKVANSIVVIGLIILLIISIICAVGIGSVKIPVADVYRIILYKIFGIKG
LESAIQGQFVDIIWQIRLPRVLLGVVVGMGLALGGVVMQATVQNPLADPYILGISSGAILGATFFILVGSNILTGTFQSV
GIAFWAFIGALMSSIMVFKLSSIGGRITSTKLVLSGMVVSIICSAFSSLMVYLTNDNNAVRSISEWAMGSLTGGKWSNLW
FPTIITFILIAFFLCQYRIMNTMLLGDEAAITLGIDLSKYRKLYMIMVSILTGVLVSSCGIIGFIGLVIPHITRSLVGSN
HKNNLPVAILIGGIFLVWADVLARIILKNMEMPIGIITSVIGAPFFIYIILKRAYSF
>Mature_377_residues
MLRNYIQSYLNNMKDILKSKSTSRGKKNLEPVKVANSIVVIGLIILLIISIICAVGIGSVKIPVADVYRIILYKIFGIKG
LESAIQGQFVDIIWQIRLPRVLLGVVVGMGLALGGVVMQATVQNPLADPYILGISSGAILGATFFILVGSNILTGTFQSV
GIAFWAFIGALMSSIMVFKLSSIGGRITSTKLVLSGMVVSIICSAFSSLMVYLTNDNNAVRSISEWAMGSLTGGKWSNLW
FPTIITFILIAFFLCQYRIMNTMLLGDEAAITLGIDLSKYRKLYMIMVSILTGVLVSSCGIIGFIGLVIPHITRSLVGSN
HKNNLPVAILIGGIFLVWADVLARIILKNMEMPIGIITSVIGAPFFIYIILKRAYSF

Specific function: Part of the binding-protein-dependent transport system for hemin; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=280, Percent_Identity=36.7857142857143, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1790740, Length=282, Percent_Identity=36.1702127659575, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1790741, Length=340, Percent_Identity=29.7058823529412, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786805, Length=297, Percent_Identity=30.6397306397306, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1786347, Length=289, Percent_Identity=27.3356401384083, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786804, Length=283, Percent_Identity=29.6819787985866, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 40870; Mature: 40870

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRNYIQSYLNNMKDILKSKSTSRGKKNLEPVKVANSIVVIGLIILLIISIICAVGIGSV
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KIPVADVYRIILYKIFGIKGLESAIQGQFVDIIWQIRLPRVLLGVVVGMGLALGGVVMQA
CCCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVQNPLADPYILGISSGAILGATFFILVGSNILTGTFQSVGIAFWAFIGALMSSIMVFKL
HHCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSIGGRITSTKLVLSGMVVSIICSAFSSLMVYLTNDNNAVRSISEWAMGSLTGGKWSNLW
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCCCCCCCCCH
FPTIITFILIAFFLCQYRIMNTMLLGDEAAITLGIDLSKYRKLYMIMVSILTGVLVSSCG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
IIGFIGLVIPHITRSLVGSNHKNNLPVAILIGGIFLVWADVLARIILKNMEMPIGIITSV
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
IGAPFFIYIILKRAYSF
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRNYIQSYLNNMKDILKSKSTSRGKKNLEPVKVANSIVVIGLIILLIISIICAVGIGSV
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KIPVADVYRIILYKIFGIKGLESAIQGQFVDIIWQIRLPRVLLGVVVGMGLALGGVVMQA
CCCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVQNPLADPYILGISSGAILGATFFILVGSNILTGTFQSVGIAFWAFIGALMSSIMVFKL
HHCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSIGGRITSTKLVLSGMVVSIICSAFSSLMVYLTNDNNAVRSISEWAMGSLTGGKWSNLW
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCCCCCCCCCH
FPTIITFILIAFFLCQYRIMNTMLLGDEAAITLGIDLSKYRKLYMIMVSILTGVLVSSCG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
IIGFIGLVIPHITRSLVGSNHKNNLPVAILIGGIFLVWADVLARIILKNMEMPIGIITSV
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
IGAPFFIYIILKRAYSF
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]