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The map label for this gene is mtnA [H]

Identifier: 28210656

GI number: 28210656

Start: 1008007

End: 1009059

Strand: Direct

Name: mtnA [H]

Synonym: CTC00945

Alternate gene names: 28210656

Gene position: 1008007-1009059 (Clockwise)

Preceding gene: 28210655

Following gene: 28210657

Centisome position: 36.01

GC content: 32.95

Gene sequence:

>1053_bases
ATGGAAAGATCAGATAAAGATTTAGCTTTCATGCTTAGATATGAAAATGTAGCTTGGTATGATGGCGGTAAGGTAAAAAT
ATTAGATAGAAGGATTTATCCAAAAGAAGTAAAGTTTGTTACATGTAATACCCATGAAGAAGTTGCAAAAGCTATTACAG
ATATGGTAACTCAAAGTGCTGGTCCGTATACAGCAGCAGGTATGGGTATGGCTTTAGCTGCATATGAGTGTAGAAGATTA
TCTTATAAAGAGCAAATTGAATATCTTGAAAATGCAGCTTATAAATTGGCAAACGCAAGACCTACAACAGCAAATAGGAT
GACGCTAGTAGTTAAGGGATGTTTAGAGGCTGCCCAAATAGCTATGAAAAATGGAGAAAAGGTTGACCAGGTAATTTTTG
AACATACTGTTAAGTCCATGAATAATCGTTATTCAAGAATTGGTGAGGTAGCAAAATATCTAGTAGATATGTTTCCTCAA
AAGGGTAATATAATGACACAATGTTTTGGAGAAACTATTGTTGGAATGATGTTAAAAGAAGCCAAAAACCGAAATAAAAA
TATTAAACTATTTTGTCCAGAAACTAGACCATATTTACAAGGAGCCAGACTTACTGCAAGTGTAGCCTACGATCAAGGAT
TTGATGTTACTGTAATTACAGATAATATGCCTGCATTTACTATGAAAAATAAAAATATAGATGTATTTACATCAGCAGCG
GATTCCATTTGTTTGGACGGACATATAGTAAATAAGGTAGGAACACTACAAATAGCTATAGTAGCTAAATATTTTGAGGT
TCCATATTTTGTAACAGGTATTCCAGATAGAGATCATAAGAGCATTTATCAAGTTGAAATTGAGGAAAGAGATCCTAAGC
AAGTCCTAGAATTTAGAGGTATTAAGAATACTATGGAGGGAGTTAAAGGATATTACCCATCTTTTGATATTACTCCTCCT
CATTTAGTAAGTGGTGTAGTTACAGATAAGGGTATATTCAGTCCTTATGATTTAGATAGATATTTTCAGACAAAGGTAGA
AAATTATTATTAA

Upstream 100 bases:

>100_bases
TCAGATAAGGAAATGGACAAAATGTTAGGATTATTTCAAAGCTATGGACAAGTAAAAAAATAAGAATAATAATTAAAACG
CAAAGAAAGGTAGGATTTAT

Downstream 100 bases:

>100_bases
AAACACAGAATAAATTTAAGGAGTTGATAACTTGTCTAGATTTGATTCACATTTTAGAATGGAAACAGAAGACGCTATAC
TTTATGCAAAAGAAAAATTA

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MERSDKDLAFMLRYENVAWYDGGKVKILDRRIYPKEVKFVTCNTHEEVAKAITDMVTQSAGPYTAAGMGMALAAYECRRL
SYKEQIEYLENAAYKLANARPTTANRMTLVVKGCLEAAQIAMKNGEKVDQVIFEHTVKSMNNRYSRIGEVAKYLVDMFPQ
KGNIMTQCFGETIVGMMLKEAKNRNKNIKLFCPETRPYLQGARLTASVAYDQGFDVTVITDNMPAFTMKNKNIDVFTSAA
DSICLDGHIVNKVGTLQIAIVAKYFEVPYFVTGIPDRDHKSIYQVEIEERDPKQVLEFRGIKNTMEGVKGYYPSFDITPP
HLVSGVVTDKGIFSPYDLDRYFQTKVENYY

Sequences:

>Translated_350_residues
MERSDKDLAFMLRYENVAWYDGGKVKILDRRIYPKEVKFVTCNTHEEVAKAITDMVTQSAGPYTAAGMGMALAAYECRRL
SYKEQIEYLENAAYKLANARPTTANRMTLVVKGCLEAAQIAMKNGEKVDQVIFEHTVKSMNNRYSRIGEVAKYLVDMFPQ
KGNIMTQCFGETIVGMMLKEAKNRNKNIKLFCPETRPYLQGARLTASVAYDQGFDVTVITDNMPAFTMKNKNIDVFTSAA
DSICLDGHIVNKVGTLQIAIVAKYFEVPYFVTGIPDRDHKSIYQVEIEERDPKQVLEFRGIKNTMEGVKGYYPSFDITPP
HLVSGVVTDKGIFSPYDLDRYFQTKVENYY
>Mature_350_residues
MERSDKDLAFMLRYENVAWYDGGKVKILDRRIYPKEVKFVTCNTHEEVAKAITDMVTQSAGPYTAAGMGMALAAYECRRL
SYKEQIEYLENAAYKLANARPTTANRMTLVVKGCLEAAQIAMKNGEKVDQVIFEHTVKSMNNRYSRIGEVAKYLVDMFPQ
KGNIMTQCFGETIVGMMLKEAKNRNKNIKLFCPETRPYLQGARLTASVAYDQGFDVTVITDNMPAFTMKNKNIDVFTSAA
DSICLDGHIVNKVGTLQIAIVAKYFEVPYFVTGIPDRDHKSIYQVEIEERDPKQVLEFRGIKNTMEGVKGYYPSFDITPP
HLVSGVVTDKGIFSPYDLDRYFQTKVENYY

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=367, Percent_Identity=26.4305177111717, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI23943880, Length=345, Percent_Identity=26.0869565217391, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17557462, Length=345, Percent_Identity=24.6376811594203, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325375, Length=393, Percent_Identity=23.6641221374046, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357667, Length=372, Percent_Identity=27.6881720430108, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24651647, Length=372, Percent_Identity=27.6881720430108, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 39750; Mature: 39750

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSDKDLAFMLRYENVAWYDGGKVKILDRRIYPKEVKFVTCNTHEEVAKAITDMVTQSA
CCCCCCCEEEEEEECCEEEECCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHCCC
GPYTAAGMGMALAAYECRRLSYKEQIEYLENAAYKLANARPTTANRMTLVVKGCLEAAQI
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
AMKNGEKVDQVIFEHTVKSMNNRYSRIGEVAKYLVDMFPQKGNIMTQCFGETIVGMMLKE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AKNRNKNIKLFCPETRPYLQGARLTASVAYDQGFDVTVITDNMPAFTMKNKNIDVFTSAA
HHCCCCCEEEECCCCCCHHCCCEEEEEEEECCCCEEEEEECCCCEEEECCCCCEEEECCC
DSICLDGHIVNKVGTLQIAIVAKYFEVPYFVTGIPDRDHKSIYQVEIEERDPKQVLEFRG
CCEEECCEEECCCCEEEEEEEEHHHCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHC
IKNTMEGVKGYYPSFDITPPHLVSGVVTDKGIFSPYDLDRYFQTKVENYY
CHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MERSDKDLAFMLRYENVAWYDGGKVKILDRRIYPKEVKFVTCNTHEEVAKAITDMVTQSA
CCCCCCCEEEEEEECCEEEECCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHCCC
GPYTAAGMGMALAAYECRRLSYKEQIEYLENAAYKLANARPTTANRMTLVVKGCLEAAQI
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
AMKNGEKVDQVIFEHTVKSMNNRYSRIGEVAKYLVDMFPQKGNIMTQCFGETIVGMMLKE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AKNRNKNIKLFCPETRPYLQGARLTASVAYDQGFDVTVITDNMPAFTMKNKNIDVFTSAA
HHCCCCCEEEECCCCCCHHCCCEEEEEEEECCCCEEEEEECCCCEEEECCCCCEEEECCC
DSICLDGHIVNKVGTLQIAIVAKYFEVPYFVTGIPDRDHKSIYQVEIEERDPKQVLEFRG
CCEEECCEEECCCCEEEEEEEEHHHCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHC
IKNTMEGVKGYYPSFDITPPHLVSGVVTDKGIFSPYDLDRYFQTKVENYY
CHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA