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The map label for this gene is cobO [H]

Identifier: 28210466

GI number: 28210466

Start: 769281

End: 769817

Strand: Direct

Name: cobO [H]

Synonym: CTC00746

Alternate gene names: 28210466

Gene position: 769281-769817 (Clockwise)

Preceding gene: 28210465

Following gene: 28210467

Centisome position: 27.48

GC content: 28.31

Gene sequence:

>537_bases
TTGTTTGGGGGAAAAAACATGGAACAAAAAGGATATATTCAAGTTTATACAGGGAATGGAAAAGGGAAAACTACTGCGGC
ATTGGGATTGGCATTAAGAGCAACTTGTACAGGGAAAAAGGTTTTCATGGGTCAATTTGTAAAGGGTATGAAATATAGTG
AATTAAACGCCATGGATTATTTACCATATTTTATTATAGAAAGATTTGGAAAGAAATGTTTTATATACAATGATCCTACT
CAAGATGATATAGATAGAGCAGTTAAAGGATTAAAAAGATGTGAAGAAATAATAAACTCTGAAGAATATGACATAGTAAT
TTTAGATGAAATAAATATAGCGTTATACTATAAATTATTTTCAGCAGAAGATGTTATAAAAATTTTAGATAAAAAACCTG
AAAAAACAGAAATTATTTTAACAGGAAGATATGCACCACAAGAAATAATAGATAGAGCAGATCTAGTTACTGAAATGGGA
GAAATAAAACATTACTATTATAAAGGAGTAAAATGTAGGAAGGGTATAGAAAATTAA

Upstream 100 bases:

>100_bases
CGAACTATTATGTAAAAGTTGCCAAACTGTATGTAAACATAATGCTATAGATTTACCAAATAGGAAGGATATGTTAGAAT
ATTTTTATATAGAATAATAA

Downstream 100 bases:

>100_bases
AACATGTTAATTTAAAAGTTAAAAAGTGCCACATTATAATTAGTTATAATGTGGTATTTTTTATAATAGTATAATTAAAC
AGTATTAAAACATTTAATTA

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MFGGKNMEQKGYIQVYTGNGKGKTTAALGLALRATCTGKKVFMGQFVKGMKYSELNAMDYLPYFIIERFGKKCFIYNDPT
QDDIDRAVKGLKRCEEIINSEEYDIVILDEINIALYYKLFSAEDVIKILDKKPEKTEIILTGRYAPQEIIDRADLVTEMG
EIKHYYYKGVKCRKGIEN

Sequences:

>Translated_178_residues
MFGGKNMEQKGYIQVYTGNGKGKTTAALGLALRATCTGKKVFMGQFVKGMKYSELNAMDYLPYFIIERFGKKCFIYNDPT
QDDIDRAVKGLKRCEEIINSEEYDIVILDEINIALYYKLFSAEDVIKILDKKPEKTEIILTGRYAPQEIIDRADLVTEMG
EIKHYYYKGVKCRKGIEN
>Mature_178_residues
MFGGKNMEQKGYIQVYTGNGKGKTTAALGLALRATCTGKKVFMGQFVKGMKYSELNAMDYLPYFIIERFGKKCFIYNDPT
QDDIDRAVKGLKRCEEIINSEEYDIVILDEINIALYYKLFSAEDVIKILDKKPEKTEIILTGRYAPQEIIDRADLVTEMG
EIKHYYYKGVKCRKGIEN

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=176, Percent_Identity=32.3863636363636, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 20418; Mature: 20418

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGGKNMEQKGYIQVYTGNGKGKTTAALGLALRATCTGKKVFMGQFVKGMKYSELNAMDY
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHEEECCCCHHHHHHHHCCCCCCCCCHHHH
LPYFIIERFGKKCFIYNDPTQDDIDRAVKGLKRCEEIINSEEYDIVILDEINIALYYKLF
HHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEC
SAEDVIKILDKKPEKTEIILTGRYAPQEIIDRADLVTEMGEIKHYYYKGVKCRKGIEN
CHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure
MFGGKNMEQKGYIQVYTGNGKGKTTAALGLALRATCTGKKVFMGQFVKGMKYSELNAMDY
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHEEECCCCHHHHHHHHCCCCCCCCCHHHH
LPYFIIERFGKKCFIYNDPTQDDIDRAVKGLKRCEEIINSEEYDIVILDEINIALYYKLF
HHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEC
SAEDVIKILDKKPEKTEIILTGRYAPQEIIDRADLVTEMGEIKHYYYKGVKCRKGIEN
CHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]