Click here to switch to the map view.

The map label for this gene is cbiJ [H]

Identifier: 28210460

GI number: 28210460

Start: 764990

End: 765760

Strand: Direct

Name: cbiJ [H]

Synonym: CTC00740

Alternate gene names: 28210460

Gene position: 764990-765760 (Clockwise)

Preceding gene: 28210459

Following gene: 28210461

Centisome position: 27.33

GC content: 25.42

Gene sequence:

>771_bases
ATGATTGGTTTAATTAGCGGAACATCCGAAGGAAAAGAACTTCTTTCAAATTTAAACAATTATACAGATGACATATTAGT
ATCCACAGCTACATCCTATGGTGGAGATTTATTAAAGGATTATAAATATAAATATTTAAACATAACTCCATTAGATAGGG
AAAATATGATAAAACTTTTTAAAGAAAAGAAGGTAGAAGTTTTAATAGATGCTTCTCATCCTTATGCTTTAGAAGTAAGT
AAAAATGCTATGGAAGTTTGTAATCATACGGATATAGAATATATTAGATTTGAAAGAGAAAAAGTTATTGAAAAATTTTT
AGAAAAAGAAAAAGTATTAGTAGTGGAAAATTATGAAGATTTGTACTCAAAATTAAAAGATATAAAAGGAAATATACTAA
ACACCACAGGTAGTAGAAATATAGAAAAGATTATAAGATTAAGTTTGGAAAATAGAATAATTCATAGAGTTCTTCCATCT
TTAAAAGTTATAGAAGAATGTTTTCATTTAGGTCTAGAACTACACAATATTATAGCCGTTAAAGGACCTATTAGTTATGA
TTTAAATAGGGCTTTTATAAGAGAATATGATGCTAAGGCCATATTACTTAAAGATAGCGGCAAAGAAGGCGGAACAGAAG
AAAAAATAAAAGCTGCTATAGATGAAAATATATGTGCAATTGTAGTAGATAGAAAAAGCTTAGATTATAAAAATAAATTT
AATAACAAAGAAGAGGTCATTAAATATTTAAAAAAATTACAATACATATAA

Upstream 100 bases:

>100_bases
TGTTTTCTATTGTAATTATAGGTAACAGCCAAAGTTATATAAAAGAAGGTAAACTTATAACACCAAGAGGTTATTCTTTA
TAAAATCTGGAGGATTTTTT

Downstream 100 bases:

>100_bases
AAGGAGTATCAATATAATATGTGTGGTAACTCAGTGGAATAACTCTCCTAATAAATTAAAATAAATATTAATAATTAGGA
GAGGATAATATTATGAAAAC

Product: cobalt-precorrin-6x reductase

Products: Precorrin 6A; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MIGLISGTSEGKELLSNLNNYTDDILVSTATSYGGDLLKDYKYKYLNITPLDRENMIKLFKEKKVEVLIDASHPYALEVS
KNAMEVCNHTDIEYIRFEREKVIEKFLEKEKVLVVENYEDLYSKLKDIKGNILNTTGSRNIEKIIRLSLENRIIHRVLPS
LKVIEECFHLGLELHNIIAVKGPISYDLNRAFIREYDAKAILLKDSGKEGGTEEKIKAAIDENICAIVVDRKSLDYKNKF
NNKEEVIKYLKKLQYI

Sequences:

>Translated_256_residues
MIGLISGTSEGKELLSNLNNYTDDILVSTATSYGGDLLKDYKYKYLNITPLDRENMIKLFKEKKVEVLIDASHPYALEVS
KNAMEVCNHTDIEYIRFEREKVIEKFLEKEKVLVVENYEDLYSKLKDIKGNILNTTGSRNIEKIIRLSLENRIIHRVLPS
LKVIEECFHLGLELHNIIAVKGPISYDLNRAFIREYDAKAILLKDSGKEGGTEEKIKAAIDENICAIVVDRKSLDYKNKF
NNKEEVIKYLKKLQYI
>Mature_256_residues
MIGLISGTSEGKELLSNLNNYTDDILVSTATSYGGDLLKDYKYKYLNITPLDRENMIKLFKEKKVEVLIDASHPYALEVS
KNAMEVCNHTDIEYIRFEREKVIEKFLEKEKVLVVENYEDLYSKLKDIKGNILNTTGSRNIEKIIRLSLENRIIHRVLPS
LKVIEECFHLGLELHNIIAVKGPISYDLNRAFIREYDAKAILLKDSGKEGGTEEKIKAAIDENICAIVVDRKSLDYKNKF
NNKEEVIKYLKKLQYI

Specific function: Catalyzes the reduction of the macrocycle of cobalt- precorrin-6X into cobalt-precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: 1.3.1.54

Molecular weight: Translated: 29539; Mature: 29539

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGLISGTSEGKELLSNLNNYTDDILVSTATSYGGDLLKDYKYKYLNITPLDRENMIKLF
CEEECCCCCHHHHHHHHHHCCHHHHHEECHHHCCHHHHHHCCCEEEEECCCCHHHHHHHH
KEKKVEVLIDASHPYALEVSKNAMEVCNHTDIEYIRFEREKVIEKFLEKEKVLVVENYED
HHCCEEEEEECCCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHH
LYSKLKDIKGNILNTTGSRNIEKIIRLSLENRIIHRVLPSLKVIEECFHLGLELHNIIAV
HHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEE
KGPISYDLNRAFIREYDAKAILLKDSGKEGGTEEKIKAAIDENICAIVVDRKSLDYKNKF
CCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHC
NNKEEVIKYLKKLQYI
CCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIGLISGTSEGKELLSNLNNYTDDILVSTATSYGGDLLKDYKYKYLNITPLDRENMIKLF
CEEECCCCCHHHHHHHHHHCCHHHHHEECHHHCCHHHHHHCCCEEEEECCCCHHHHHHHH
KEKKVEVLIDASHPYALEVSKNAMEVCNHTDIEYIRFEREKVIEKFLEKEKVLVVENYED
HHCCEEEEEECCCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECHHH
LYSKLKDIKGNILNTTGSRNIEKIIRLSLENRIIHRVLPSLKVIEECFHLGLELHNIIAV
HHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEE
KGPISYDLNRAFIREYDAKAILLKDSGKEGGTEEKIKAAIDENICAIVVDRKSLDYKNKF
CCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEEECCCCCHHHHC
NNKEEVIKYLKKLQYI
CCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 6B; NADP+

Specific reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]