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The map label for this gene is proX [H]

Identifier: 28210369

GI number: 28210369

Start: 659881

End: 660408

Strand: Direct

Name: proX [H]

Synonym: CTC00640

Alternate gene names: 28210369

Gene position: 659881-660408 (Clockwise)

Preceding gene: 28210368

Following gene: 28210370

Centisome position: 23.57

GC content: 29.92

Gene sequence:

>528_bases
ATGGAGGGGTTTACCTCTATAAATTATGGAGGAAATAAAACAATGGAAAGTAAACAAGAGATAATAAACCTTTTAAATAC
ATCAAATTTGGAGTATGAAGTAATTTCACATGAAGCAGTTTTTACAATTGACGAAATGCTTGCTTTGAATCTCCCTAAAG
CCAAGTTTGTGGCTAAAAATTTATTTGTTCGTGATGATAAAAAACGAAATTATTTTTTATTTGTAGTGCGAGAAGAAAAA
ATGGTTAATTTAAAGCAAATAAGAGAAAGAATTAACTCGTGCCCGCTTAGTTTTGCTTCTGAAAGTGATTTGTATCAGTA
TTTAAGTTTACCTAAAGGTGCTGTAACACCATTCGGTGTCATTAATGATAAAACACATAACGTAAAAGTATATATTGATG
CTGACTTTAAACATTCACTTATCGGCGTTCATCCAAATGAAAATACCGCTACTGTTTGGTTAAAAACAAAAGATTTGGTT
GACTTAATAAAACAACATGGAAATCAAGTAGAATACATTGATTTTTAA

Upstream 100 bases:

>100_bases
ATCAACAGATAAATAGTAATTTGCAGTTAACATACTTTATATAGAATTAACTGAGAAAGGAGGATTTTATTATGAAAAAC
AAGAAAAATAAAGAACTTTT

Downstream 100 bases:

>100_bases
TTTTGATATTTGTTAAATTCCAATTTACCTATTAGTTAAAAATTTTTAACTAGAAAAATTAAATTAACCAATAGTTAATT
TTTATGAATAAAACATGAAA

Product: putative DNA-binding protein

Products: NA

Alternate protein names: Prolyl-tRNA deacylase proX [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MEGFTSINYGGNKTMESKQEIINLLNTSNLEYEVISHEAVFTIDEMLALNLPKAKFVAKNLFVRDDKKRNYFLFVVREEK
MVNLKQIRERINSCPLSFASESDLYQYLSLPKGAVTPFGVINDKTHNVKVYIDADFKHSLIGVHPNENTATVWLKTKDLV
DLIKQHGNQVEYIDF

Sequences:

>Translated_175_residues
MEGFTSINYGGNKTMESKQEIINLLNTSNLEYEVISHEAVFTIDEMLALNLPKAKFVAKNLFVRDDKKRNYFLFVVREEK
MVNLKQIRERINSCPLSFASESDLYQYLSLPKGAVTPFGVINDKTHNVKVYIDADFKHSLIGVHPNENTATVWLKTKDLV
DLIKQHGNQVEYIDF
>Mature_175_residues
MEGFTSINYGGNKTMESKQEIINLLNTSNLEYEVISHEAVFTIDEMLALNLPKAKFVAKNLFVRDDKKRNYFLFVVREEK
MVNLKQIRERINSCPLSFASESDLYQYLSLPKGAVTPFGVINDKTHNVKVYIDADFKHSLIGVHPNENTATVWLKTKDLV
DLIKQHGNQVEYIDF

Specific function: Functions in trans to edit the amino acid moiety from incorrectly charged Ala-tRNA(Pro). Has weak activity on correctly charged tRNA(Ala), tRNA(Gly) as well as tRNA(Cys), tRNA(Met), tRNA(Pro), tRNA(Ser) and tRNA(Leu) [H]

COG id: COG3760

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prolyl-tRNA editing family. ProX subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007214 [H]

Pfam domain/function: PF04073 YbaK [H]

EC number: NA

Molecular weight: Translated: 20148; Mature: 20148

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGFTSINYGGNKTMESKQEIINLLNTSNLEYEVISHEAVFTIDEMLALNLPKAKFVAKN
CCCCEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCEEEEHHHHHHCCCCHHHHHHHH
LFVRDDKKRNYFLFVVREEKMVNLKQIRERINSCPLSFASESDLYQYLSLPKGAVTPFGV
HEEECCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEE
INDKTHNVKVYIDADFKHSLIGVHPNENTATVWLKTKDLVDLIKQHGNQVEYIDF
ECCCCCEEEEEEECCCCCEEEEECCCCCEEEEEEECHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure
MEGFTSINYGGNKTMESKQEIINLLNTSNLEYEVISHEAVFTIDEMLALNLPKAKFVAKN
CCCCEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCEEEEHHHHHHCCCCHHHHHHHH
LFVRDDKKRNYFLFVVREEKMVNLKQIRERINSCPLSFASESDLYQYLSLPKGAVTPFGV
HEEECCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEE
INDKTHNVKVYIDADFKHSLIGVHPNENTATVWLKTKDLVDLIKQHGNQVEYIDF
ECCCCCEEEEEEECCCCCEEEEECCCCCEEEEEEECHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10085076 [H]