Click here to switch to the map view.

The map label for this gene is mviN [H]

Identifier: 28210337

GI number: 28210337

Start: 626687

End: 628057

Strand: Direct

Name: mviN [H]

Synonym: CTC00603

Alternate gene names: 28210337

Gene position: 626687-628057 (Clockwise)

Preceding gene: 28210336

Following gene: 28210339

Centisome position: 22.39

GC content: 30.56

Gene sequence:

>1371_bases
GTGGAAAAAGATATAGATAGGTCAAAGCAGTTAGGTGAAGAAAAAGTAGGTACACTTCTGTTTAAGTTTTCCTTGCCAGC
AATAGTAGGAATGTTAGTTAATGCATTATATAATATGGTGGATAGAGTGTTTATAGGAAGAGGGGTAGGAGCCCTTGCTA
TATCAGGATTAGCAGTAGGATTTCCTTTATCTATAATAGGTATGGCATTTGGAATGCTTGTAGGGATAGGTTCTTCTACT
ATGATATCTATAAAGCTTGGAGAAAAAAAGAAGGATGAGGCAGAAAGAATATTAGGTAACTCTTTAATATTAATTATATT
AATATCAATTTGTTTAAGTATAGTAGGTCTTATATTTTTAGACGATATATTAAAAATATTTGGTGCCAGTGCAGAAACCC
TACCTTATGCTAGAGATTACATGAAATACATAGTTGCAGGGGCATTACTTCAAAATATAGGATTTAGTATGAATAATATA
ATTCGTGCAGAAGGAAATCCTAAAATAGCTATGGCAACAATGTTAATAGGTGCCATTATAAATACTATATTAGATCCCAT
TTTTATATTTGTATTTAAAATGGGAATAAAGGGAGCAGCTCTTGCAACTATATTTGCTCAAACAGTATCATCTATTTGGG
TACTATATTACTTCTTTAGTGGAAGAAGTACTTTAAAAATAAGAAGAGAAAATTTAAATTTGCATAAAGGAACTATAAAA
ACCATAATGTCCATAGGAATATCTCCTTTTTCCATGCAAATAGCAGCTAGCTTAGTTACAACTATTTTTAATAAAAATTT
ACTTACACATGGTGGAGATTTAGCGGTAGGTGCAATGGGTATTGTTAATAGCATATCTATGTTGTTTTTTATGCCTATGT
TTGGTATAAATCAGGGTATGCAACCTATAATAGGATATAACTATGGAGCAAAACAATATAAAAGAGTTAGAAAAACTTTA
AAACTTGCCATAACATCAGCTATGATTATTGCAACTATAGGATTTATAGTTGTTGAAGTTTTTCCAACGGCATTAATAAA
GATTTTTAATAAAGATGAACAGTTGGTATCTATAGGAGCTTATGGTATGAGAATATTTTTATCTATGCTTCCTATAATAG
GATTCCAAGTGGTAAGTTCAAACTACTTTCAAGCTGTAGGAAAGGCAAAGATTGCAATATTTTTAAGTCTTTTAAGACAG
GTTATATTACTTATTCCAATGCTTTTAATACTACCACCAATATTCGGACTAAATGGAGTATGGATAGTAGGACCTGTATC
TGATGTTTTAGCAGCTATAGTAACTGTATTCTTCCTTTCTAAGAATATGAAACAATTAATGAAGTTAGAAAAAGCTATAT
CCTCTAAATAA

Upstream 100 bases:

>100_bases
AATTGCCCTTAAAATGTTTCATGTTTGAAATTTATTTTTATTTAATATATAATTATATAATTGGTTATTATACAGAAGAT
GTCATAAAGGAGGAAAAATT

Downstream 100 bases:

>100_bases
AATATAATATAATGGCGTTGTAAAAGATTATTTTATTCTTTTACAACGCCATTATTTATTATATATTTTCTTGTATTAGT
CCTTTTCTGTAAGCTACTAA

Product: Na+ driven multidrug efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MEKDIDRSKQLGEEKVGTLLFKFSLPAIVGMLVNALYNMVDRVFIGRGVGALAISGLAVGFPLSIIGMAFGMLVGIGSST
MISIKLGEKKKDEAERILGNSLILIILISICLSIVGLIFLDDILKIFGASAETLPYARDYMKYIVAGALLQNIGFSMNNI
IRAEGNPKIAMATMLIGAIINTILDPIFIFVFKMGIKGAALATIFAQTVSSIWVLYYFFSGRSTLKIRRENLNLHKGTIK
TIMSIGISPFSMQIAASLVTTIFNKNLLTHGGDLAVGAMGIVNSISMLFFMPMFGINQGMQPIIGYNYGAKQYKRVRKTL
KLAITSAMIIATIGFIVVEVFPTALIKIFNKDEQLVSIGAYGMRIFLSMLPIIGFQVVSSNYFQAVGKAKIAIFLSLLRQ
VILLIPMLLILPPIFGLNGVWIVGPVSDVLAAIVTVFFLSKNMKQLMKLEKAISSK

Sequences:

>Translated_456_residues
MEKDIDRSKQLGEEKVGTLLFKFSLPAIVGMLVNALYNMVDRVFIGRGVGALAISGLAVGFPLSIIGMAFGMLVGIGSST
MISIKLGEKKKDEAERILGNSLILIILISICLSIVGLIFLDDILKIFGASAETLPYARDYMKYIVAGALLQNIGFSMNNI
IRAEGNPKIAMATMLIGAIINTILDPIFIFVFKMGIKGAALATIFAQTVSSIWVLYYFFSGRSTLKIRRENLNLHKGTIK
TIMSIGISPFSMQIAASLVTTIFNKNLLTHGGDLAVGAMGIVNSISMLFFMPMFGINQGMQPIIGYNYGAKQYKRVRKTL
KLAITSAMIIATIGFIVVEVFPTALIKIFNKDEQLVSIGAYGMRIFLSMLPIIGFQVVSSNYFQAVGKAKIAIFLSLLRQ
VILLIPMLLILPPIFGLNGVWIVGPVSDVLAAIVTVFFLSKNMKQLMKLEKAISSK
>Mature_456_residues
MEKDIDRSKQLGEEKVGTLLFKFSLPAIVGMLVNALYNMVDRVFIGRGVGALAISGLAVGFPLSIIGMAFGMLVGIGSST
MISIKLGEKKKDEAERILGNSLILIILISICLSIVGLIFLDDILKIFGASAETLPYARDYMKYIVAGALLQNIGFSMNNI
IRAEGNPKIAMATMLIGAIINTILDPIFIFVFKMGIKGAALATIFAQTVSSIWVLYYFFSGRSTLKIRRENLNLHKGTIK
TIMSIGISPFSMQIAASLVTTIFNKNLLTHGGDLAVGAMGIVNSISMLFFMPMFGINQGMQPIIGYNYGAKQYKRVRKTL
KLAITSAMIIATIGFIVVEVFPTALIKIFNKDEQLVSIGAYGMRIFLSMLPIIGFQVVSSNYFQAVGKAKIAIFLSLLRQ
VILLIPMLLILPPIFGLNGVWIVGPVSDVLAAIVTVFFLSKNMKQLMKLEKAISSK

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49667; Mature: 49667

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKDIDRSKQLGEEKVGTLLFKFSLPAIVGMLVNALYNMVDRVFIGRGVGALAISGLAVG
CCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FPLSIIGMAFGMLVGIGSSTMISIKLGEKKKDEAERILGNSLILIILISICLSIVGLIFL
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DDILKIFGASAETLPYARDYMKYIVAGALLQNIGFSMNNIIRAEGNPKIAMATMLIGAII
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCEEEECCCCCHHHHHHHHHHHH
NTILDPIFIFVFKMGIKGAALATIFAQTVSSIWVLYYFFSGRSTLKIRRENLNLHKGTIK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
TIMSIGISPFSMQIAASLVTTIFNKNLLTHGGDLAVGAMGIVNSISMLFFMPMFGINQGM
HHHHHCCCCHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
QPIIGYNYGAKQYKRVRKTLKLAITSAMIIATIGFIVVEVFPTALIKIFNKDEQLVSIGA
CCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YGMRIFLSMLPIIGFQVVSSNYFQAVGKAKIAIFLSLLRQVILLIPMLLILPPIFGLNGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
WIVGPVSDVLAAIVTVFFLSKNMKQLMKLEKAISSK
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKDIDRSKQLGEEKVGTLLFKFSLPAIVGMLVNALYNMVDRVFIGRGVGALAISGLAVG
CCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FPLSIIGMAFGMLVGIGSSTMISIKLGEKKKDEAERILGNSLILIILISICLSIVGLIFL
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DDILKIFGASAETLPYARDYMKYIVAGALLQNIGFSMNNIIRAEGNPKIAMATMLIGAII
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCEEEECCCCCHHHHHHHHHHHH
NTILDPIFIFVFKMGIKGAALATIFAQTVSSIWVLYYFFSGRSTLKIRRENLNLHKGTIK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
TIMSIGISPFSMQIAASLVTTIFNKNLLTHGGDLAVGAMGIVNSISMLFFMPMFGINQGM
HHHHHCCCCHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
QPIIGYNYGAKQYKRVRKTLKLAITSAMIIATIGFIVVEVFPTALIKIFNKDEQLVSIGA
CCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YGMRIFLSMLPIIGFQVVSSNYFQAVGKAKIAIFLSLLRQVILLIPMLLILPPIFGLNGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
WIVGPVSDVLAAIVTVFFLSKNMKQLMKLEKAISSK
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA