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The map label for this gene is 28210307

Identifier: 28210307

GI number: 28210307

Start: 590397

End: 591416

Strand: Direct

Name: 28210307

Synonym: CTC00571

Alternate gene names: NA

Gene position: 590397-591416 (Clockwise)

Preceding gene: 28210306

Following gene: 28210308

Centisome position: 21.09

GC content: 25.78

Gene sequence:

>1020_bases
GTGATAGAATATAATATAATATATATTGATTTTGTTAAGAATTTTTTAAAAAAGTATTATGGCATTGGAGTGATAAAATT
GTCAATAATAGATTTGCATTGTGATACTATATATAAAATAACAAATTGCAAAGATAAAATAAATTTAAAGGATAATAATA
TATCTATAGATTTAAACAAAATGAGGAAGGGAAAAGTTAACGGTGAATTTTTTGCTCTTTTTATAGATAGAGAAGAAACA
GAAACTCCGCTTAAAACTTGCAATAAAATGTTAGATAGATTCTATGAAGAAATGGATGAAAATAAAGAAACTATAAAACT
AACTAAAAATTATACACAGTACAAAGAAAATATTAGGAATAACATCATGTCTGCATTTCTAACTATAGAAGGCGGAGAAG
CATTAGAAGGAGAAATTTATAATTTGAGAAACTTTTATAGACTAGGAGTAAGACTATTAACCTTAACCTGGAATTATGAA
AATGAAATAGGTTATCCTAACTGTAATAAAATATTTATGCAAAAAGGTTTAAAGAAATTTGGAATAGAAATAGTAGAAGA
AATGAATAGATTGGGAATGATAATAGATGTATCTCATTTATCAGATGGTGGATTTTATGATGTAGCTAAATACTCAAAGG
TTCCTTTTATAGCATCTCATTCAAATGCAAGAAGCATAACAAACCATGGCAGAAACTTAACAGATGATATGATAAAAATC
TTAAGTGAAAAGGGTGGAGTTATAGGAATAAATTTTTGTAATGAATTCTTAGGAGATACAGAGATAAGTAGAGTTGAAGA
TATGATTACTCACATAAAATATATAAAAAATACAGGAGGAATAGATTGTATTGCATTAGGTAGTGATTTTGATGGAATAG
ATTGTGAAGTAGAAATAGAAGATATATCTCAAATGGATAAACTGATAGAAAAATTAAGTTCATCAGGATTCAATGAAAGT
GAGATAGAAAGAATATGTTTTAAGAATGCAGAAAGAGTAATAAAAGAAGTATTAAAATAA

Upstream 100 bases:

>100_bases
CAATTTATCTTCATATGAATGTAAATTACAAGTTTTAGAAACTTTTATAGAAGAAAACTTTTAAACATGCCCTAGGGCAT
GTTTTTTATTATAGGAATAA

Downstream 100 bases:

>100_bases
AAAAAATAGGTATATGGGGATTAGTAATATAAAAAGATATAGTAAATGTTATAAAATTAAAAGGAGATGTTTTAAATGAA
GAAGGAAGATTTGAAGCTAG

Product: membrane dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIEYNIIYIDFVKNFLKKYYGIGVIKLSIIDLHCDTIYKITNCKDKINLKDNNISIDLNKMRKGKVNGEFFALFIDREET
ETPLKTCNKMLDRFYEEMDENKETIKLTKNYTQYKENIRNNIMSAFLTIEGGEALEGEIYNLRNFYRLGVRLLTLTWNYE
NEIGYPNCNKIFMQKGLKKFGIEIVEEMNRLGMIIDVSHLSDGGFYDVAKYSKVPFIASHSNARSITNHGRNLTDDMIKI
LSEKGGVIGINFCNEFLGDTEISRVEDMITHIKYIKNTGGIDCIALGSDFDGIDCEVEIEDISQMDKLIEKLSSSGFNES
EIERICFKNAERVIKEVLK

Sequences:

>Translated_339_residues
MIEYNIIYIDFVKNFLKKYYGIGVIKLSIIDLHCDTIYKITNCKDKINLKDNNISIDLNKMRKGKVNGEFFALFIDREET
ETPLKTCNKMLDRFYEEMDENKETIKLTKNYTQYKENIRNNIMSAFLTIEGGEALEGEIYNLRNFYRLGVRLLTLTWNYE
NEIGYPNCNKIFMQKGLKKFGIEIVEEMNRLGMIIDVSHLSDGGFYDVAKYSKVPFIASHSNARSITNHGRNLTDDMIKI
LSEKGGVIGINFCNEFLGDTEISRVEDMITHIKYIKNTGGIDCIALGSDFDGIDCEVEIEDISQMDKLIEKLSSSGFNES
EIERICFKNAERVIKEVLK
>Mature_339_residues
MIEYNIIYIDFVKNFLKKYYGIGVIKLSIIDLHCDTIYKITNCKDKINLKDNNISIDLNKMRKGKVNGEFFALFIDREET
ETPLKTCNKMLDRFYEEMDENKETIKLTKNYTQYKENIRNNIMSAFLTIEGGEALEGEIYNLRNFYRLGVRLLTLTWNYE
NEIGYPNCNKIFMQKGLKKFGIEIVEEMNRLGMIIDVSHLSDGGFYDVAKYSKVPFIASHSNARSITNHGRNLTDDMIKI
LSEKGGVIGINFCNEFLGDTEISRVEDMITHIKYIKNTGGIDCIALGSDFDGIDCEVEIEDISQMDKLIEKLSSSGFNES
EIERICFKNAERVIKEVLK

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=334, Percent_Identity=27.5449101796407, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4758190, Length=334, Percent_Identity=27.5449101796407, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI11641269, Length=327, Percent_Identity=29.3577981651376, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI193211608, Length=307, Percent_Identity=27.6872964169381, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI193211610, Length=307, Percent_Identity=27.6872964169381, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI221475880, Length=298, Percent_Identity=30.8724832214765, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI161083233, Length=221, Percent_Identity=34.841628959276, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281362638, Length=290, Percent_Identity=28.6206896551724, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281362636, Length=290, Percent_Identity=28.6206896551724, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21356391, Length=190, Percent_Identity=28.9473684210526, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 39135; Mature: 39135

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00869 RENAL_DIPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEYNIIYIDFVKNFLKKYYGIGVIKLSIIDLHCDTIYKITNCKDKINLKDNNISIDLNK
CEEEEEEEHHHHHHHHHHHHCCEEEEEEEEEEECCCEEEECCCCCCCEECCCCEEEEHHH
MRKGKVNGEFFALFIDREETETPLKTCNKMLDRFYEEMDENKETIKLTKNYTQYKENIRN
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
NIMSAFLTIEGGEALEGEIYNLRNFYRLGVRLLTLTWNYENEIGYPNCNKIFMQKGLKKF
HHHHHEEEECCCCCCCCHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
GIEIVEEMNRLGMIIDVSHLSDGGFYDVAKYSKVPFIASHSNARSITNHGRNLTDDMIKI
HHHHHHHHHHCCEEEEEEECCCCCCEEHHHHCCCCEEECCCCCHHHHHCCCCCHHHHHHH
LSEKGGVIGINFCNEFLGDTEISRVEDMITHIKYIKNTGGIDCIALGSDFDGIDCEVEIE
HHHCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEHH
DISQMDKLIEKLSSSGFNESEIERICFKNAERVIKEVLK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MIEYNIIYIDFVKNFLKKYYGIGVIKLSIIDLHCDTIYKITNCKDKINLKDNNISIDLNK
CEEEEEEEHHHHHHHHHHHHCCEEEEEEEEEEECCCEEEECCCCCCCEECCCCEEEEHHH
MRKGKVNGEFFALFIDREETETPLKTCNKMLDRFYEEMDENKETIKLTKNYTQYKENIRN
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
NIMSAFLTIEGGEALEGEIYNLRNFYRLGVRLLTLTWNYENEIGYPNCNKIFMQKGLKKF
HHHHHEEEECCCCCCCCHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
GIEIVEEMNRLGMIIDVSHLSDGGFYDVAKYSKVPFIASHSNARSITNHGRNLTDDMIKI
HHHHHHHHHHCCEEEEEEECCCCCCEEHHHHCCCCEEECCCCCHHHHHCCCCCHHHHHHH
LSEKGGVIGINFCNEFLGDTEISRVEDMITHIKYIKNTGGIDCIALGSDFDGIDCEVEIE
HHHCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEHH
DISQMDKLIEKLSSSGFNESEIERICFKNAERVIKEVLK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]