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The map label for this gene is perR [H]

Identifier: 28210267

GI number: 28210267

Start: 538767

End: 539180

Strand: Direct

Name: perR [H]

Synonym: CTC00527

Alternate gene names: 28210267

Gene position: 538767-539180 (Clockwise)

Preceding gene: 28210266

Following gene: 28210268

Centisome position: 19.25

GC content: 24.15

Gene sequence:

>414_bases
ATGAATATTGAAAAGTTTTTAAAAGAAAATAAATTGAGAGTTACAAAAGGAAGAAGAAATATACTTTATATATTAAGTGA
CAATAAAGATGCTATTACAGCAGAGTATATACACCATAAGTTAATAGAAAAAAATATTAACATTGATTTATCAACAGTTT
ATAGAAATTTAGAGTTATTTAATAAAGAAGGTATAATAGATAAATTTGATGTAGGAGATGGTAAGTATAATTACTTGATA
AATCCAGATAAACATAAGCATATTTTAGAATGCGCTATATGTCATAAAGAAATTGAAATAGATTGTCCTATTAAACAATT
GGAACAAATTATAAAAAGCAGAACAGGATTTACAATAGAAGAAGAGTTAGATATAAAGATAAAAGGCTTGTGTGAGGAAT
GCAGTGAGAAATAA

Upstream 100 bases:

>100_bases
GGTTTGAAAATGATATTTTTTTAAAGAAAAATAGAAACAATTTAAAATAGGTATATGAATGATAAATAATTAATATAATA
TTTATTTATAAGGTGATATT

Downstream 100 bases:

>100_bases
AGTTTTTGTATATAAAAATATAAGAGACAGCTTTTTTATAGTTATAGATTTATAAAAAAGCTGTCTCTTATAATATTTTT
AGGGGACAGATCACAAGAAA

Product: ferric uptake regulation protein (Fe2+/Zn2+)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MNIEKFLKENKLRVTKGRRNILYILSDNKDAITAEYIHHKLIEKNINIDLSTVYRNLELFNKEGIIDKFDVGDGKYNYLI
NPDKHKHILECAICHKEIEIDCPIKQLEQIIKSRTGFTIEEELDIKIKGLCEECSEK

Sequences:

>Translated_137_residues
MNIEKFLKENKLRVTKGRRNILYILSDNKDAITAEYIHHKLIEKNINIDLSTVYRNLELFNKEGIIDKFDVGDGKYNYLI
NPDKHKHILECAICHKEIEIDCPIKQLEQIIKSRTGFTIEEELDIKIKGLCEECSEK
>Mature_137_residues
MNIEKFLKENKLRVTKGRRNILYILSDNKDAITAEYIHHKLIEKNINIDLSTVYRNLELFNKEGIIDKFDVGDGKYNYLI
NPDKHKHILECAICHKEIEIDCPIKQLEQIIKSRTGFTIEEELDIKIKGLCEECSEK

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16091; Mature: 16091

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEKFLKENKLRVTKGRRNILYILSDNKDAITAEYIHHKLIEKNINIDLSTVYRNLELF
CCHHHHHHCCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHH
NKEGIIDKFDVGDGKYNYLINPDKHKHILECAICHKEIEIDCPIKQLEQIIKSRTGFTIE
CCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEE
EELDIKIKGLCEECSEK
CCCCEEEEEHHHHCCCC
>Mature Secondary Structure
MNIEKFLKENKLRVTKGRRNILYILSDNKDAITAEYIHHKLIEKNINIDLSTVYRNLELF
CCHHHHHHCCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHH
NKEGIIDKFDVGDGKYNYLINPDKHKHILECAICHKEIEIDCPIKQLEQIIKSRTGFTIE
CCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEE
EELDIKIKGLCEECSEK
CCCCEEEEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]