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The map label for this gene is bdhA [H]

Identifier: 28210161

GI number: 28210161

Start: 402595

End: 403758

Strand: Direct

Name: bdhA [H]

Synonym: CTC00408

Alternate gene names: 28210161

Gene position: 402595-403758 (Clockwise)

Preceding gene: 28210160

Following gene: 28210162

Centisome position: 14.38

GC content: 30.41

Gene sequence:

>1164_bases
ATGTTGAATTTTAATTATTCTATACCTACTAAAATATTCTTTGGTAAAGGTCAAATAGAGATTCTAGGTAAAGAGATAAA
GAAATATGGAAATAAAGTATTGATAGTTTATGGTGGAGGAAGTATAAAGAAAAATGGTGTATATGATGAAATAGTTAACA
TATTTAAAGATAATAATATAAATTTTTGGGAATTATCTGGTGTAGAGCCTAATCCAAGAATAACCACTGTTAGAAAAGGT
ATTAAAGTGTGTAAAGAAAATGATATAGATTTTATATTAGCAGTAGGTGGAGGAAGCAGTATAGATTGTTCAAAGGTGAT
AGCAGCAGGTTATTATTATAAAGGAGATCCATGGGATATTGTGTTAAATTCTAGCAAAATAGAAAATGCAATCCCTTTAG
GAACTATTTTAACTCTGTCTGCCACAGGGTCAGAAATGAATGCAGGAGCAGTTATAACTAATTTAGAAACTAATGAGAAA
TTAGGAACACATCATCCATCTATGGCACCTAAATTTTCTATATTAGATCCTTCTTATACTTTTACCGTTCCAGCAAAACA
TACAGCAGCAGGTATTGCAGATATAATGAGTCATACTTTTGAAAACTACTTTAGCAAAACAAAAGAAGCTTATCTTCAAA
ATAGAATGGCTGAATCCATACTTAAAACCTGTATAGAATATGGAAAAGTAGCTATGGAAGAACCAGAAAATTATGAAGCA
AGAGCTAACTTAATGTGGGCTTCTAGTCTTGCTATAAATGGCATACTAAGTTATGGAAAGGAAACAAAATGGAGCGTGCA
TCCAATAGAACATGAATTAAGTGCTTTTTACGATATTACTCATGGAATAGGGCTTGCAATCTTAACCCCTTATTGGATGG
AATATGTTTTAGATGATAGTACATTAGACAATTTTGTAGAATATGGAATAAATGTTTGGAATATTAATGATAAAGAAGAT
AAATATAATATAGCTAATAAATCCATAGAAAAAACTAGAGAATATTTTACTTCTTTAGGAATCCCATCAACGTTAAAAGA
AGTTGGAATAGAGGAAGAAAAATTAGCTGAAATGGCAAAGGCTGCTACAAGAAGAGGTGATGTAGGAGGTTTTAGACCAC
TTAAAGAAGAAGATGTTTTAAAAATATATAAATTAGCTTTCTAA

Upstream 100 bases:

>100_bases
GGTTTCTTGGGGGGATTTATTTTGAAAAGTTTTACTTTTACATATTGTATATAGTAAAATTAGATGTATAATTATTTGAA
AAAGAAAGGGGAATTTAAAG

Downstream 100 bases:

>100_bases
GAATATTCACAACTATTCACTGTTAGCTATTAGCTAAATAAAGGATGTGTTTATATGAATATTGCATTAATAGCAGGAAC
CCCATTTGATACCCAAATGG

Product: NADH-dependent butanol dehydrogenase A

Products: NA

Alternate protein names: BDH I [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MLNFNYSIPTKIFFGKGQIEILGKEIKKYGNKVLIVYGGGSIKKNGVYDEIVNIFKDNNINFWELSGVEPNPRITTVRKG
IKVCKENDIDFILAVGGGSSIDCSKVIAAGYYYKGDPWDIVLNSSKIENAIPLGTILTLSATGSEMNAGAVITNLETNEK
LGTHHPSMAPKFSILDPSYTFTVPAKHTAAGIADIMSHTFENYFSKTKEAYLQNRMAESILKTCIEYGKVAMEEPENYEA
RANLMWASSLAINGILSYGKETKWSVHPIEHELSAFYDITHGIGLAILTPYWMEYVLDDSTLDNFVEYGINVWNINDKED
KYNIANKSIEKTREYFTSLGIPSTLKEVGIEEEKLAEMAKAATRRGDVGGFRPLKEEDVLKIYKLAF

Sequences:

>Translated_387_residues
MLNFNYSIPTKIFFGKGQIEILGKEIKKYGNKVLIVYGGGSIKKNGVYDEIVNIFKDNNINFWELSGVEPNPRITTVRKG
IKVCKENDIDFILAVGGGSSIDCSKVIAAGYYYKGDPWDIVLNSSKIENAIPLGTILTLSATGSEMNAGAVITNLETNEK
LGTHHPSMAPKFSILDPSYTFTVPAKHTAAGIADIMSHTFENYFSKTKEAYLQNRMAESILKTCIEYGKVAMEEPENYEA
RANLMWASSLAINGILSYGKETKWSVHPIEHELSAFYDITHGIGLAILTPYWMEYVLDDSTLDNFVEYGINVWNINDKED
KYNIANKSIEKTREYFTSLGIPSTLKEVGIEEEKLAEMAKAATRRGDVGGFRPLKEEDVLKIYKLAF
>Mature_387_residues
MLNFNYSIPTKIFFGKGQIEILGKEIKKYGNKVLIVYGGGSIKKNGVYDEIVNIFKDNNINFWELSGVEPNPRITTVRKG
IKVCKENDIDFILAVGGGSSIDCSKVIAAGYYYKGDPWDIVLNSSKIENAIPLGTILTLSATGSEMNAGAVITNLETNEK
LGTHHPSMAPKFSILDPSYTFTVPAKHTAAGIADIMSHTFENYFSKTKEAYLQNRMAESILKTCIEYGKVAMEEPENYEA
RANLMWASSLAINGILSYGKETKWSVHPIEHELSAFYDITHGIGLAILTPYWMEYVLDDSTLDNFVEYGINVWNINDKED
KYNIANKSIEKTREYFTSLGIPSTLKEVGIEEEKLAEMAKAATRRGDVGGFRPLKEEDVLKIYKLAF

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=427, Percent_Identity=19.9063231850117, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789386, Length=370, Percent_Identity=41.6216216216216, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI48994951, Length=395, Percent_Identity=27.3417721518987, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789163, Length=381, Percent_Identity=25.7217847769029, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1787493, Length=376, Percent_Identity=23.936170212766, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI87082107, Length=366, Percent_Identity=24.0437158469945, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17537053, Length=395, Percent_Identity=22.7848101265823, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321181, Length=360, Percent_Identity=28.3333333333333, Blast_Score=119, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 43219; Mature: 43219

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFNYSIPTKIFFGKGQIEILGKEIKKYGNKVLIVYGGGSIKKNGVYDEIVNIFKDNNI
CCCCCCCCCCEEEECCCCEEEHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHCCCC
NFWELSGVEPNPRITTVRKGIKVCKENDIDFILAVGGGSSIDCSKVIAAGYYYKGDPWDI
CEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCEEECCCCEEE
VLNSSKIENAIPLGTILTLSATGSEMNAGAVITNLETNEKLGTHHPSMAPKFSILDPSYT
EEECCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCEE
FTVPAKHTAAGIADIMSHTFENYFSKTKEAYLQNRMAESILKTCIEYGKVAMEEPENYEA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCH
RANLMWASSLAINGILSYGKETKWSVHPIEHELSAFYDITHGIGLAILTPYWMEYVLDDS
HEEEEEHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCH
TLDNFVEYGINVWNINDKEDKYNIANKSIEKTREYFTSLGIPSTLKEVGIEEEKLAEMAK
HHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHH
AATRRGDVGGFRPLKEEDVLKIYKLAF
HHHHCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLNFNYSIPTKIFFGKGQIEILGKEIKKYGNKVLIVYGGGSIKKNGVYDEIVNIFKDNNI
CCCCCCCCCCEEEECCCCEEEHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHCCCC
NFWELSGVEPNPRITTVRKGIKVCKENDIDFILAVGGGSSIDCSKVIAAGYYYKGDPWDI
CEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCEEECCCCEEE
VLNSSKIENAIPLGTILTLSATGSEMNAGAVITNLETNEKLGTHHPSMAPKFSILDPSYT
EEECCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCEE
FTVPAKHTAAGIADIMSHTFENYFSKTKEAYLQNRMAESILKTCIEYGKVAMEEPENYEA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCH
RANLMWASSLAINGILSYGKETKWSVHPIEHELSAFYDITHGIGLAILTPYWMEYVLDDS
HEEEEEHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCH
TLDNFVEYGINVWNINDKEDKYNIANKSIEKTREYFTSLGIPSTLKEVGIEEEKLAEMAK
HHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHH
AATRRGDVGGFRPLKEEDVLKIYKLAF
HHHHCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385386; 11466286; 1809209 [H]