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The map label for this gene is thrS [H]

Identifier: 28210102

GI number: 28210102

Start: 332318

End: 333976

Strand: Direct

Name: thrS [H]

Synonym: CTC00344

Alternate gene names: 28210102

Gene position: 332318-333976 (Clockwise)

Preceding gene: 28210099

Following gene: 28210103

Centisome position: 11.87

GC content: 29.23

Gene sequence:

>1659_bases
ATGGAAAAATTAAAAATAAACTTAGAGGGGAAAAAAGAAGTTTTAATAGAAAAAGGAAAAACTTTGAGGGATATATTAGA
AAATATTCATGTTGAAAATAAGTTTCCTATAGTGTTAGGAGAAATGAATGGAAAAGTATACGAATTAAATTCACCAATTG
TCGAAGAGGGACAATTAGAATTTATAGACTTAGGTAGTGATACTGGGAATAGAGCATATATAAGAACACTTCAATTTATA
CTTATAAAAGCTACTTTAGAAGAGTTCCCTGGAGCAAATATTTCAATACAACATTCATTAAGTAAGGGATTATATTGTGA
AATAAGCAAAGGGAAGATTTTAACTGAAAAAGAGCTTGAGAAAATAAAAGCAAGAATGAAAGAAATAATATATAAGGATA
TGCCTATAAAAGAAGAATACTTTACAAAAGAAGAAACTATGGAAATGCTTAAAAAATACAATATGAATGATAGAATAAAA
CTTCTTAGCAATTTGCAGTTAGATAAAATAAAATTGTATGAACTAGATGGAGTATATGAGTATTTTTATGGACCTATGGG
AGAAAGTACTGGTATTATAAGAGAATTTGATTTAATGTATTATGAACCAGGATTTATATTAAGATATCCTACTAAAGAAG
AACCAGATAGATTACCTGTTTTCCTAGAACATAGAAAACTTGCTAATATATTTAGAGAAACAGAGATATGGGGAGATATA
TTAGAGGTGCCAAATGTAGGATCATTAAACGAAAAGGTAAACAGTGGAGAGATAATTGACATAATCAGGGTATCTGAAGC
ATTACATGAGAAAAAAGCTGCTAATATAGCGGATATAATAAAAGATAGAGAGAATATAAGGTTAATATTAATAGCTGGTC
CATCCTCATCAGGAAAAACTACTTTTGCAAGAAGACTTGCAATACAACTTAGAGTAAACGGTCTAATACCCATTCCTATA
GGTTTAGATGATTATTTTGTGGAAAGGGACGATACTCCAAAGGATGAAAATGGGGAGTATGATTTTGAATCCATACATGC
TGTGGACTTAGAACTTTTCAATGAACATTTAACTAGGATATTAAAAGGAGAAGAAGTGCACATACCTAAATACAATTTTA
TAACAGGAAAAAGAGACTGGAATGGTACAAAAGTAAAATTACCGTTAAACGGAATATTAATTGTAGAAGGAATACATGGA
TTAAATAATTTATTAACTTCTTCTATAGCTGATGAAAATAAATTTAAAGTATATATAAGTGCTTTAACACAGTTAAATTT
AGATAATCACAACAGGATAGCTACTACAGATGTAAGAATGATTAGGAGAATAGTAAGGGATAATATGTCAAGGGGATATA
GTGCAGAAGAAACTTTAAAAATGTGGCCTTCTATAAGAAGAGGTGAGGAAAAAAATATATTTGTATTTCAAGAGAATGCA
GATATTATGTTTAACTCTACTTTAGTTTATGAGTTGTGTGTATTAAAGAAATTTGCCCTAAGAGAACTACAAAAAATAGA
GCCTACAAGTCCAGTATATTTAGAAGCTTACAGATTAAAAAGTATTTTAAATTTCTTTAAGGAAGTTGATACGTCGCACA
TACCTGAAAATTCAATATTGAGAGAGTTTATAGGTGGAAGTTGGTTTCATGATCATTAA

Upstream 100 bases:

>100_bases
TATTGTTTCAAAAAAATAAAAAATTATTAGTATTTTATATAGAAAAGTACTATCTTTCAAATATAATAAATTATATATAT
AAAAAATAGGGGATGATAAT

Downstream 100 bases:

>100_bases
TTTATAAAAATAAGTAATAAACGCTACTATCCATAAATATAGATAAAGTAAATCTAATAAGAATTGTGGTGGATAGTATG
GGACACAGAAAAGTCATAGA

Product: uridine kinase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MEKLKINLEGKKEVLIEKGKTLRDILENIHVENKFPIVLGEMNGKVYELNSPIVEEGQLEFIDLGSDTGNRAYIRTLQFI
LIKATLEEFPGANISIQHSLSKGLYCEISKGKILTEKELEKIKARMKEIIYKDMPIKEEYFTKEETMEMLKKYNMNDRIK
LLSNLQLDKIKLYELDGVYEYFYGPMGESTGIIREFDLMYYEPGFILRYPTKEEPDRLPVFLEHRKLANIFRETEIWGDI
LEVPNVGSLNEKVNSGEIIDIIRVSEALHEKKAANIADIIKDRENIRLILIAGPSSSGKTTFARRLAIQLRVNGLIPIPI
GLDDYFVERDDTPKDENGEYDFESIHAVDLELFNEHLTRILKGEEVHIPKYNFITGKRDWNGTKVKLPLNGILIVEGIHG
LNNLLTSSIADENKFKVYISALTQLNLDNHNRIATTDVRMIRRIVRDNMSRGYSAEETLKMWPSIRRGEEKNIFVFQENA
DIMFNSTLVYELCVLKKFALRELQKIEPTSPVYLEAYRLKSILNFFKEVDTSHIPENSILREFIGGSWFHDH

Sequences:

>Translated_552_residues
MEKLKINLEGKKEVLIEKGKTLRDILENIHVENKFPIVLGEMNGKVYELNSPIVEEGQLEFIDLGSDTGNRAYIRTLQFI
LIKATLEEFPGANISIQHSLSKGLYCEISKGKILTEKELEKIKARMKEIIYKDMPIKEEYFTKEETMEMLKKYNMNDRIK
LLSNLQLDKIKLYELDGVYEYFYGPMGESTGIIREFDLMYYEPGFILRYPTKEEPDRLPVFLEHRKLANIFRETEIWGDI
LEVPNVGSLNEKVNSGEIIDIIRVSEALHEKKAANIADIIKDRENIRLILIAGPSSSGKTTFARRLAIQLRVNGLIPIPI
GLDDYFVERDDTPKDENGEYDFESIHAVDLELFNEHLTRILKGEEVHIPKYNFITGKRDWNGTKVKLPLNGILIVEGIHG
LNNLLTSSIADENKFKVYISALTQLNLDNHNRIATTDVRMIRRIVRDNMSRGYSAEETLKMWPSIRRGEEKNIFVFQENA
DIMFNSTLVYELCVLKKFALRELQKIEPTSPVYLEAYRLKSILNFFKEVDTSHIPENSILREFIGGSWFHDH
>Mature_552_residues
MEKLKINLEGKKEVLIEKGKTLRDILENIHVENKFPIVLGEMNGKVYELNSPIVEEGQLEFIDLGSDTGNRAYIRTLQFI
LIKATLEEFPGANISIQHSLSKGLYCEISKGKILTEKELEKIKARMKEIIYKDMPIKEEYFTKEETMEMLKKYNMNDRIK
LLSNLQLDKIKLYELDGVYEYFYGPMGESTGIIREFDLMYYEPGFILRYPTKEEPDRLPVFLEHRKLANIFRETEIWGDI
LEVPNVGSLNEKVNSGEIIDIIRVSEALHEKKAANIADIIKDRENIRLILIAGPSSSGKTTFARRLAIQLRVNGLIPIPI
GLDDYFVERDDTPKDENGEYDFESIHAVDLELFNEHLTRILKGEEVHIPKYNFITGKRDWNGTKVKLPLNGILIVEGIHG
LNNLLTSSIADENKFKVYISALTQLNLDNHNRIATTDVRMIRRIVRDNMSRGYSAEETLKMWPSIRRGEEKNIFVFQENA
DIMFNSTLVYELCVLKKFALRELQKIEPTSPVYLEAYRLKSILNFFKEVDTSHIPENSILREFIGGSWFHDH

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 63947; Mature: 63947

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLKINLEGKKEVLIEKGKTLRDILENIHVENKFPIVLGEMNGKVYELNSPIVEEGQLE
CCEEEEECCCCHHHHHHCCCHHHHHHHHCCCCCCCCEEEECCCCEEEECCCCCCCCCCEE
FIDLGSDTGNRAYIRTLQFILIKATLEEFPGANISIQHSLSKGLYCEISKGKILTEKELE
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCEECHHHHH
KIKARMKEIIYKDMPIKEEYFTKEETMEMLKKYNMNDRIKLLSNLQLDKIKLYELDGVYE
HHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEEECCHHH
YFYGPMGESTGIIREFDLMYYEPGFILRYPTKEEPDRLPVFLEHRKLANIFRETEIWGDI
HHCCCCCCCCCCEEEEEEEEECCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
LEVPNVGSLNEKVNSGEIIDIIRVSEALHEKKAANIADIIKDRENIRLILIAGPSSSGKT
HCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEECCCCCCCH
TFARRLAIQLRVNGLIPIPIGLDDYFVERDDTPKDENGEYDFESIHAVDLELFNEHLTRI
HHEEEEEEEEEECCEEEEECCCCHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LKGEEVHIPKYNFITGKRDWNGTKVKLPLNGILIVEGIHGLNNLLTSSIADENKFKVYIS
HCCCEEECCCEEEEECCCCCCCCEEEEECCCEEEEECHHHHHHHHHHHHCCCCCEEEEEE
ALTQLNLDNHNRIATTDVRMIRRIVRDNMSRGYSAEETLKMWPSIRRGEEKNIFVFQENA
EHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHCCCCCCEEEEECCC
DIMFNSTLVYELCVLKKFALRELQKIEPTSPVYLEAYRLKSILNFFKEVDTSHIPENSIL
CEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
REFIGGSWFHDH
HHHHCCCCCCCC
>Mature Secondary Structure
MEKLKINLEGKKEVLIEKGKTLRDILENIHVENKFPIVLGEMNGKVYELNSPIVEEGQLE
CCEEEEECCCCHHHHHHCCCHHHHHHHHCCCCCCCCEEEECCCCEEEECCCCCCCCCCEE
FIDLGSDTGNRAYIRTLQFILIKATLEEFPGANISIQHSLSKGLYCEISKGKILTEKELE
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCEECHHHHH
KIKARMKEIIYKDMPIKEEYFTKEETMEMLKKYNMNDRIKLLSNLQLDKIKLYELDGVYE
HHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEEECCHHH
YFYGPMGESTGIIREFDLMYYEPGFILRYPTKEEPDRLPVFLEHRKLANIFRETEIWGDI
HHCCCCCCCCCCEEEEEEEEECCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
LEVPNVGSLNEKVNSGEIIDIIRVSEALHEKKAANIADIIKDRENIRLILIAGPSSSGKT
HCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEECCCCCCCH
TFARRLAIQLRVNGLIPIPIGLDDYFVERDDTPKDENGEYDFESIHAVDLELFNEHLTRI
HHEEEEEEEEEECCEEEEECCCCHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LKGEEVHIPKYNFITGKRDWNGTKVKLPLNGILIVEGIHGLNNLLTSSIADENKFKVYIS
HCCCEEECCCEEEEECCCCCCCCEEEEECCCEEEEECHHHHHHHHHHHHCCCCCEEEEEE
ALTQLNLDNHNRIATTDVRMIRRIVRDNMSRGYSAEETLKMWPSIRRGEEKNIFVFQENA
EHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHCCCCCCEEEEECCC
DIMFNSTLVYELCVLKKFALRELQKIEPTSPVYLEAYRLKSILNFFKEVDTSHIPENSIL
CEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
REFIGGSWFHDH
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA