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The map label for this gene is comF [H]

Identifier: 28210084

GI number: 28210084

Start: 308122

End: 308796

Strand: Direct

Name: comF [H]

Synonym: CTC00324

Alternate gene names: 28210084

Gene position: 308122-308796 (Clockwise)

Preceding gene: 28210083

Following gene: 28210085

Centisome position: 11.01

GC content: 25.04

Gene sequence:

>675_bases
ATGGGAAATGGGTCTTTTAAGTATTTAAGCATAATAAAAGAAAGTATAGCATCTTTATTATATCCTTCTAAAAATCAATG
TGTTATATGTGGAACTTATACAGAAAAAGGAATATGTATGAATTGTTTTTCTAAAATAAATTGGTGTAAAGGTAATTTTT
ATATAGAAGAAGAAAAATTTAAAGTTTGTTGTTATAGTATAGCCTATTATTCTTCAATTATAATGGAAATGATATTAAAT
TTAAAATACAAAAAGGATTTTAGAAGTGGCGAGATATTGGCAAGTTACATGGTAGAAAAGATAATAGAAGAAAATATTTC
ATGTGATTTAATAACATATATTCCTTCAGATAAAAAAACTTTAAAAAGAAGAGGCTTTAACCAAAGTGAATTTTTAGCTA
AGAAAATTGGCAGTACATTGGAGTTACCTGTGAAAGGTGTTTTAATTAAAGCAAAAAGTACCAAAGAACAAAAGTCATTG
GATAGGGAAAATAGATGGATAAATTTAAAGGAAGGCTTTAAACTTGATAACAAAAATGAAATTGTAAATAAAAAAATAAT
TTTAATAGATGATATCGTAACTACTGGAGCTACAGTGTATTTTGCCTCAAAAGAACTATCTAATGTAAATATAAAAGAAT
TAAATGTATTGACTGTGGCCAAAATTGTTGTATAA

Upstream 100 bases:

>100_bases
AAAGAGAAGGATCTATGAAAGAAGTTATATTTGTATGTAACGAAGAAACTAATGAAATAGATAAAACAAAACAAATAACT
AGAGAGTTTAATAAAGAAGC

Downstream 100 bases:

>100_bases
TTTTATTGTATTAAGTTAGGTTTGTGATTGAAAGTCGATGCCAGCCGCAGGCAAAGCGATCCACGTAAGTTAAATAAAAT
ATTTAATGAGCATGGTGCGG

Product: competence protein F

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MGNGSFKYLSIIKESIASLLYPSKNQCVICGTYTEKGICMNCFSKINWCKGNFYIEEEKFKVCCYSIAYYSSIIMEMILN
LKYKKDFRSGEILASYMVEKIIEENISCDLITYIPSDKKTLKRRGFNQSEFLAKKIGSTLELPVKGVLIKAKSTKEQKSL
DRENRWINLKEGFKLDNKNEIVNKKIILIDDIVTTGATVYFASKELSNVNIKELNVLTVAKIVV

Sequences:

>Translated_224_residues
MGNGSFKYLSIIKESIASLLYPSKNQCVICGTYTEKGICMNCFSKINWCKGNFYIEEEKFKVCCYSIAYYSSIIMEMILN
LKYKKDFRSGEILASYMVEKIIEENISCDLITYIPSDKKTLKRRGFNQSEFLAKKIGSTLELPVKGVLIKAKSTKEQKSL
DRENRWINLKEGFKLDNKNEIVNKKIILIDDIVTTGATVYFASKELSNVNIKELNVLTVAKIVV
>Mature_223_residues
GNGSFKYLSIIKESIASLLYPSKNQCVICGTYTEKGICMNCFSKINWCKGNFYIEEEKFKVCCYSIAYYSSIIMEMILNL
KYKKDFRSGEILASYMVEKIIEENISCDLITYIPSDKKTLKRRGFNQSEFLAKKIGSTLELPVKGVLIKAKSTKEQKSLD
RENRWINLKEGFKLDNKNEIVNKKIILIDDIVTTGATVYFASKELSNVNIKELNVLTVAKIVV

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 25604; Mature: 25473

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNGSFKYLSIIKESIASLLYPSKNQCVICGTYTEKGICMNCFSKINWCKGNFYIEEEKF
CCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCEEEECCCH
KVCCYSIAYYSSIIMEMILNLKYKKDFRSGEILASYMVEKIIEENISCDLITYIPSDKKT
HHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
LKRRGFNQSEFLAKKIGSTLELPVKGVLIKAKSTKEQKSLDRENRWINLKEGFKLDNKNE
HHHCCCCHHHHHHHHCCCEEECCCCEEEEEECCCHHHHHHCHHHCEEEECCCCCCCCCCC
IVNKKIILIDDIVTTGATVYFASKELSNVNIKELNVLTVAKIVV
HHCCEEEEEECHHHCCEEEEEECCCCCCCCHHHHHHHHHEECCC
>Mature Secondary Structure 
GNGSFKYLSIIKESIASLLYPSKNQCVICGTYTEKGICMNCFSKINWCKGNFYIEEEKF
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCEEEECCCH
KVCCYSIAYYSSIIMEMILNLKYKKDFRSGEILASYMVEKIIEENISCDLITYIPSDKKT
HHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
LKRRGFNQSEFLAKKIGSTLELPVKGVLIKAKSTKEQKSLDRENRWINLKEGFKLDNKNE
HHHCCCCHHHHHHHHCCCEEECCCCEEEEEECCCHHHHHHCHHHCEEEECCCCCCCCCCC
IVNKKIILIDDIVTTGATVYFASKELSNVNIKELNVLTVAKIVV
HHCCEEEEEECHHHCCEEEEEECCCCCCCCHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]