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The map label for this gene is murA2

Identifier: 28210075

GI number: 28210075

Start: 296500

End: 297753

Strand: Direct

Name: murA2

Synonym: CTC00314

Alternate gene names: 28210075

Gene position: 296500-297753 (Clockwise)

Preceding gene: 28210074

Following gene: 28210076

Centisome position: 10.59

GC content: 32.62

Gene sequence:

>1254_bases
ATGAATAAAATTATTGTTAATGGGGGTAAAAGTTTAAAAGGTGAAGTTAATATAAATTCTGCTAAGAACTCTGTATTACC
TATAATAGCAGCAAGTATATTAAGTGGAGATAAATGTATTATAGAAAATGCTCCTATGTTAGAGGATGTGTTTGTAATAA
GTGAGGTTTTAAAATCAATATCTTCAGAAGTGGACATAGATAGGGATAACAATAAAATAATAATAGATACATCTAACATT
TGTAATTCAGAACCTTGTAGTGAACTTGTAAAAAAACTAAGAGCATCTTTCCTTATAATGGGACCTATGATATCTAGATT
TGGCAATTTTAAAATATCTCTTCCAGGAGGCTGTAATATAGGTACCCGTCCCATAGATCTACATCTAAAAGGTTTAAATG
CACTAGGAGCAGATATAAATATAGGATATGGGTATGTAGAAGCTAAAGCTGATAAATTAAAAGGAAATAAAATATATTTA
GATTTTCCTTCCGTAGGAGCTACAGAAAATTTAATGATGGCAGCTGTACTTGCAGAAGGGGATACTATAATACAAAATGC
AGCGGAAGAGCCAGAAATAGAAGATTTGGCTAAATTTTTAAACAGCATGGGTGCTAATATAGTTGGAGCAGGAACTGATA
CAATAAATATAATAGGGGTAAAGGATTTAAAGGGGGTAGTTCATAAACCTATATACGATAGAATAGAAGCTGGAACGTTT
ATGACTGCGGCAGCTATAACAAGGAGTAAAATAAAATTAAATGGAGTAAATGAAGGACATTTAAGACCTATAATAGCTAA
GCTAACTGAGATAGGTGTAAAAATAGATACAAATGGAGATAGTATGATAGTTGATGGAAATCATCAGCTAAAACCTGTGG
ATATAAAAACTATGCCCTATCCAGGATTTCCAACAGATATGCAAGCTCAGACAATGGCTTTATTGACTTCCATAGAAGGA
ACTAGCATAGTAACTGAAACTATATTTGAAAATAGATTTATGCATGCAACTGAAATGAAAAGAATGGGTTCAAATATAAA
GATAGATGGAAGAAGTGCTGTGATAGAAGGTGGCAATGAGTTAACAGGTTGTGAAGTTAAGGCTACAGATTTAAGAGCAG
GAGCAGCATTAATACTTTGTGGTTTAGTAGCTAGAGGAAGTACAAATGTTACAGATGTGTATCATATAGATAGAGGGTAT
GCAAACATAGAGAAAAAACTCCAAGCATTAGGAGCAGAGATTTATAGAATATAA

Upstream 100 bases:

>100_bases
AATATGTTTTAGCAAATTATTCTTCAGGTAGCTACTTAATAATGGGGGAACCGCAAATTTTTGAATTATATTAGAAATTT
ATAAAAGATGGAGGAATACT

Downstream 100 bases:

>100_bases
TAATTGGAATATAAATGTAGTTTTTTTCATATAGTTATTATAAAATACTTAAGATTAATAAAGGGAGAAAACTATATGAG
AAAAGGTGATCTAATACATT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MNKIIVNGGKSLKGEVNINSAKNSVLPIIAASILSGDKCIIENAPMLEDVFVISEVLKSISSEVDIDRDNNKIIIDTSNI
CNSEPCSELVKKLRASFLIMGPMISRFGNFKISLPGGCNIGTRPIDLHLKGLNALGADINIGYGYVEAKADKLKGNKIYL
DFPSVGATENLMMAAVLAEGDTIIQNAAEEPEIEDLAKFLNSMGANIVGAGTDTINIIGVKDLKGVVHKPIYDRIEAGTF
MTAAAITRSKIKLNGVNEGHLRPIIAKLTEIGVKIDTNGDSMIVDGNHQLKPVDIKTMPYPGFPTDMQAQTMALLTSIEG
TSIVTETIFENRFMHATEMKRMGSNIKIDGRSAVIEGGNELTGCEVKATDLRAGAALILCGLVARGSTNVTDVYHIDRGY
ANIEKKLQALGAEIYRI

Sequences:

>Translated_417_residues
MNKIIVNGGKSLKGEVNINSAKNSVLPIIAASILSGDKCIIENAPMLEDVFVISEVLKSISSEVDIDRDNNKIIIDTSNI
CNSEPCSELVKKLRASFLIMGPMISRFGNFKISLPGGCNIGTRPIDLHLKGLNALGADINIGYGYVEAKADKLKGNKIYL
DFPSVGATENLMMAAVLAEGDTIIQNAAEEPEIEDLAKFLNSMGANIVGAGTDTINIIGVKDLKGVVHKPIYDRIEAGTF
MTAAAITRSKIKLNGVNEGHLRPIIAKLTEIGVKIDTNGDSMIVDGNHQLKPVDIKTMPYPGFPTDMQAQTMALLTSIEG
TSIVTETIFENRFMHATEMKRMGSNIKIDGRSAVIEGGNELTGCEVKATDLRAGAALILCGLVARGSTNVTDVYHIDRGY
ANIEKKLQALGAEIYRI
>Mature_417_residues
MNKIIVNGGKSLKGEVNINSAKNSVLPIIAASILSGDKCIIENAPMLEDVFVISEVLKSISSEVDIDRDNNKIIIDTSNI
CNSEPCSELVKKLRASFLIMGPMISRFGNFKISLPGGCNIGTRPIDLHLKGLNALGADINIGYGYVEAKADKLKGNKIYL
DFPSVGATENLMMAAVLAEGDTIIQNAAEEPEIEDLAKFLNSMGANIVGAGTDTINIIGVKDLKGVVHKPIYDRIEAGTF
MTAAAITRSKIKLNGVNEGHLRPIIAKLTEIGVKIDTNGDSMIVDGNHQLKPVDIKTMPYPGFPTDMQAQTMALLTSIEG
TSIVTETIFENRFMHATEMKRMGSNIKIDGRSAVIEGGNELTGCEVKATDLRAGAALILCGLVARGSTNVTDVYHIDRGY
ANIEKKLQALGAEIYRI

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=47.0167064439141, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA2_CLOTE (Q898X3)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781019.1
- ProteinModelPortal:   Q898X3
- SMR:   Q898X3
- GeneID:   1059891
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC00314
- NMPDR:   fig|212717.1.peg.241
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q898X3
- ProtClustDB:   PRK09369
- BioCyc:   CTET212717:CTC_00314-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44777; Mature: 44777

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIIVNGGKSLKGEVNINSAKNSVLPIIAASILSGDKCIIENAPMLEDVFVISEVLKSI
CCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHH
SSEVDIDRDNNKIIIDTSNICNSEPCSELVKKLRASFLIMGPMISRFGNFKISLPGGCNI
HHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHEEEECHHHHHCCCEEEECCCCCCC
GTRPIDLHLKGLNALGADINIGYGYVEAKADKLKGNKIYLDFPSVGATENLMMAAVLAEG
CCCEEEEEEECCCCCCCEEECCCEEEEEEHHHCCCCEEEEECCCCCCCHHHEEEEEECCC
DTIIQNAAEEPEIEDLAKFLNSMGANIVGAGTDTINIIGVKDLKGVVHKPIYDRIEAGTF
CHHHHCCCCCCCHHHHHHHHHHCCCCEEECCCCEEEEEEEHHHHHHHCCCHHHHHHCCCC
MTAAAITRSKIKLNGVNEGHLRPIIAKLTEIGVKIDTNGDSMIVDGNHQLKPVDIKTMPY
HHHHHHHHCEEEECCCCCCCHHHHHHHHHHCCEEEECCCCEEEECCCCCEEEEEEEECCC
PGFPTDMQAQTMALLTSIEGTSIVTETIFENRFMHATEMKRMGSNIKIDGRSAVIEGGNE
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEECCCEEEEECCCC
LTGCEVKATDLRAGAALILCGLVARGSTNVTDVYHIDRGYANIEKKLQALGAEIYRI
CCCCEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKIIVNGGKSLKGEVNINSAKNSVLPIIAASILSGDKCIIENAPMLEDVFVISEVLKSI
CCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHH
SSEVDIDRDNNKIIIDTSNICNSEPCSELVKKLRASFLIMGPMISRFGNFKISLPGGCNI
HHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHEEEECHHHHHCCCEEEECCCCCCC
GTRPIDLHLKGLNALGADINIGYGYVEAKADKLKGNKIYLDFPSVGATENLMMAAVLAEG
CCCEEEEEEECCCCCCCEEECCCEEEEEEHHHCCCCEEEEECCCCCCCHHHEEEEEECCC
DTIIQNAAEEPEIEDLAKFLNSMGANIVGAGTDTINIIGVKDLKGVVHKPIYDRIEAGTF
CHHHHCCCCCCCHHHHHHHHHHCCCCEEECCCCEEEEEEEHHHHHHHCCCHHHHHHCCCC
MTAAAITRSKIKLNGVNEGHLRPIIAKLTEIGVKIDTNGDSMIVDGNHQLKPVDIKTMPY
HHHHHHHHCEEEECCCCCCCHHHHHHHHHHCCEEEECCCCEEEECCCCCEEEEEEEECCC
PGFPTDMQAQTMALLTSIEGTSIVTETIFENRFMHATEMKRMGSNIKIDGRSAVIEGGNE
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEECCCEEEEECCCC
LTGCEVKATDLRAGAALILCGLVARGSTNVTDVYHIDRGYANIEKKLQALGAEIYRI
CCCCEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129