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The map label for this gene is rnpA [H]

Identifier: 28199978

GI number: 28199978

Start: 2519116

End: 2519523

Strand: Reverse

Name: rnpA [H]

Synonym: PD2122

Alternate gene names: 28199978

Gene position: 2519523-2519116 (Counterclockwise)

Preceding gene: 28199979

Following gene: 28199977

Centisome position: 99.99

GC content: 44.85

Gene sequence:

>408_bases
TTGAATTCATGTAAGCGCTTTCCTCGTTCTGCTAGGATTTGTTTGCCTTCGGAATATTATGTCGCCTTTGAGCAAGGTCG
ACGTTATTCGTCTGTTTTATTGAGATTGCATCATCTGCCGACTTCAGGACCAGTGCGTTTGGGCCTAGTAGTTTCCCGTA
GAGTTGATATACGCGCTGTTAATCGTAATCGGATCAAACGAGCACTGCGTGAGGTAATGCGCCAGATCGCCTATAAGTTA
GTTCCAGGTGACTACGTGGTAGTTGTTCGTCAAACTGCCAAAGACGTTAGTAATGCTGAATTGAGTGTGGCCTTATTGTC
ATTGTTACGGCGCATCGGAGCATTGCCTTTAGCTTCAATTGATAACGCAATGCTGCCTTTCTTCGAACGCAATTGTTCCC
GTAAATAA

Upstream 100 bases:

>100_bases
GCTCGCCGTCGTGCTAAAGGCCGTAAGCGTTTGAGTGCTTAATTAAATTTATCCTTTTAAACGCAGCTGAAAGTCAATTT
TGTGTCTTCATTTGGGTACA

Downstream 100 bases:

>100_bases
ACGAATTAGAACCCCGTTCCGACTGAACGAGAAATTTTTCTTAAATGAACCAGACTCGTGTATTACTGATATTTTCCTGG
CTGACGGTAGCAACACTATT

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5 [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MNSCKRFPRSARICLPSEYYVAFEQGRRYSSVLLRLHHLPTSGPVRLGLVVSRRVDIRAVNRNRIKRALREVMRQIAYKL
VPGDYVVVVRQTAKDVSNAELSVALLSLLRRIGALPLASIDNAMLPFFERNCSRK

Sequences:

>Translated_135_residues
MNSCKRFPRSARICLPSEYYVAFEQGRRYSSVLLRLHHLPTSGPVRLGLVVSRRVDIRAVNRNRIKRALREVMRQIAYKL
VPGDYVVVVRQTAKDVSNAELSVALLSLLRRIGALPLASIDNAMLPFFERNCSRK
>Mature_135_residues
MNSCKRFPRSARICLPSEYYVAFEQGRRYSSVLLRLHHLPTSGPVRLGLVVSRRVDIRAVNRNRIKRALREVMRQIAYKL
VPGDYVVVVRQTAKDVSNAELSVALLSLLRRIGALPLASIDNAMLPFFERNCSRK

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family [H]

Homologues:

Organism=Escherichia coli, GI1790139, Length=109, Percent_Identity=39.4495412844037, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- ProDom:   PD003629 [H]

Pfam domain/function: PF00825 Ribonuclease_P [H]

EC number: =3.1.26.5 [H]

Molecular weight: Translated: 15423; Mature: 15423

Theoretical pI: Translated: 11.69; Mature: 11.69

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSCKRFPRSARICLPSEYYVAFEQGRRYSSVLLRLHHLPTSGPVRLGLVVSRRVDIRAV
CCCHHCCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEC
NRNRIKRALREVMRQIAYKLVPGDYVVVVRQTAKDVSNAELSVALLSLLRRIGALPLASI
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHCCCCCHHHHHHHHHHHHHHCCCCCCCC
DNAMLPFFERNCSRK
CCHHHHHHHHCCCCC
>Mature Secondary Structure
MNSCKRFPRSARICLPSEYYVAFEQGRRYSSVLLRLHHLPTSGPVRLGLVVSRRVDIRAV
CCCHHCCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEC
NRNRIKRALREVMRQIAYKLVPGDYVVVVRQTAKDVSNAELSVALLSLLRRIGALPLASI
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHCCCCCHHHHHHHHHHHHHHCCCCCCCC
DNAMLPFFERNCSRK
CCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]