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The map label for this gene is infC [H]

Identifier: 28199782

GI number: 28199782

Start: 2244925

End: 2245389

Strand: Reverse

Name: infC [H]

Synonym: PD1915

Alternate gene names: 28199782

Gene position: 2245389-2244925 (Counterclockwise)

Preceding gene: 28199783

Following gene: 28199781

Centisome position: 89.11

GC content: 47.96

Gene sequence:

>465_bases
GTGATTGGTAGTGACGGAGAAATGATTGGCGTGTTGTCGCGTGACGAAGCGCTTGCCATGGCCGAAAAAGAAGGATTGGA
TCTGGTCGAGATACAGCCTCAAGCTGATCCGCCGGTTTGTAAGGTTATGAACTTTGGCAAGTTCAAGTTCGAGCAACAAA
AGAAGGCGAACGAAGCTAAAAAGAAGACTAAACAAGTCGAGATCAAGGAACTTAAGTTCCGCCCAGTCACGGACGAGGGT
GACTACCAGATCAAGCTGCGTAACATGCGTCGTTTTCTGGAAGAGGGTGATAAAGTTAAGATTAACATTCGCTTCCGTGG
CCGTGAGATGAGCCATCAAGAATTAGGTCGACAGATGGCAGCGCGTATTGAAATGGATCTTGGTGATGATGTCGTTATTG
AATCCCGTCCCCGCTTAGAAGGGCGACAGATGGTGATGATGGTTGCGCCGAGGAAAAAAAGCTAA

Upstream 100 bases:

>100_bases
TGGACGGCGCCGATTTGATTTCCTTGGAGATTGCAATATCAGTACCTCTGACAACAAACAGAACCGTAAGAACCATGAAA
TCCGGGTACCACGTGTACGC

Downstream 100 bases:

>100_bases
GACGTCTTTCATTTAATTTTTTATCTTTGTACCGAAGCATCTCATTTACAAAATGTTTTGTCTCCTGGCATACTAGCAGA
TCAGCTTCTTGGAGCTGGTT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MIGSDGEMIGVLSRDEALAMAEKEGLDLVEIQPQADPPVCKVMNFGKFKFEQQKKANEAKKKTKQVEIKELKFRPVTDEG
DYQIKLRNMRRFLEEGDKVKINIRFRGREMSHQELGRQMAARIEMDLGDDVVIESRPRLEGRQMVMMVAPRKKS

Sequences:

>Translated_154_residues
MIGSDGEMIGVLSRDEALAMAEKEGLDLVEIQPQADPPVCKVMNFGKFKFEQQKKANEAKKKTKQVEIKELKFRPVTDEG
DYQIKLRNMRRFLEEGDKVKINIRFRGREMSHQELGRQMAARIEMDLGDDVVIESRPRLEGRQMVMMVAPRKKS
>Mature_154_residues
MIGSDGEMIGVLSRDEALAMAEKEGLDLVEIQPQADPPVCKVMNFGKFKFEQQKKANEAKKKTKQVEIKELKFRPVTDEG
DYQIKLRNMRRFLEEGDKVKINIRFRGREMSHQELGRQMAARIEMDLGDDVVIESRPRLEGRQMVMMVAPRKKS

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=154, Percent_Identity=55.8441558441558, Blast_Score=170, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17797; Mature: 17797

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGSDGEMIGVLSRDEALAMAEKEGLDLVEIQPQADPPVCKVMNFGKFKFEQQKKANEAK
CCCCCCCEEEEEECCCHHHHHHHCCCEEEEECCCCCCCHHHHCCCCCCEEHHHHHHHHHH
KKTKQVEIKELKFRPVTDEGDYQIKLRNMRRFLEEGDKVKINIRFRGREMSHQELGRQMA
HHHHCCEEEHEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHH
ARIEMDLGDDVVIESRPRLEGRQMVMMVAPRKKS
HHEECCCCCCEEECCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MIGSDGEMIGVLSRDEALAMAEKEGLDLVEIQPQADPPVCKVMNFGKFKFEQQKKANEAK
CCCCCCCEEEEEECCCHHHHHHHCCCEEEEECCCCCCCHHHHCCCCCCEEHHHHHHHHHH
KKTKQVEIKELKFRPVTDEGDYQIKLRNMRRFLEEGDKVKINIRFRGREMSHQELGRQMA
HHHHCCEEEHEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHH
ARIEMDLGDDVVIESRPRLEGRQMVMMVAPRKKS
HHEECCCCCCEEECCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]