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The map label for this gene is mraY

Identifier: 28199737

GI number: 28199737

Start: 2195522

End: 2196607

Strand: Reverse

Name: mraY

Synonym: PD1868

Alternate gene names: 28199737

Gene position: 2196607-2195522 (Counterclockwise)

Preceding gene: 28199738

Following gene: 28199736

Centisome position: 87.17

GC content: 49.45

Gene sequence:

>1086_bases
ATGTTGTTTGAGTTTGCCCGTTGGTTGCAGCAATTTGAAAGTTTGTTTGGGTTGTTCAATTACCTGACGTTCCGCAGCAT
TTTGGCGGCATTGACTGCATTGTTTTTGTCGCTGTGGATCGGGCCGGTATTGATCCAGAAGTTGTCCCAGTTTAAGGGGG
GGCAGCCGATCCGTCAGGATGGCCCGAAGATGCATTTTTCTAAAGCTGGCACGCCGACGATGGGCGGTTCGCTGATTTTG
ATGACAGTGACGTTGTCGGTGTTGTTATGGGGGGATTTGCGTAATCGCTATGTGTGGTTGGTTTTGGTGGTTATGTTGGC
TTTTGGGGCGATTGGTTGGTACGACGATTGGATCAAGCTTGCGAGGCGTGATCCGAATGGTCTGAAATCGCGTTGGAAGT
ATTTGTTGCAGTCGATCTTTGGTTTAGCTGCTGGCTTGTTTCTTTACTTTACTGCTGATGTGCCGGCGGCAGTCACTTTC
TATATCCCTATGTTCAAGTCGATCGCATTGCCGTTGACCAGCATTAGTTTTGTGGCGATCACTTATTTTTGGATTGTTGG
TTTTTCCAACGCGGTTAATTTGACGGATGGTTTAGATGGGTTGGCGATTATGCCAACGGTGTTGGTGGCGTGTGCATTAG
GGGTATTTGCTTACGCTTCGGGGAATACCTTGTTTTCCAGTTATCTGAAGATTCCCACGATTCCCGGTGCTGGCGATTTA
ATCATTATCTGTGCGGCTATTGCTGGAGCGGGTCTTGGTTTTTTGTGGTTTAACGCGTATCCGGCGATGGTGTTCATGGG
GGATATCGGTGCTCTGGCATTGGGTGCGGTACTTGGCACGATTGCGGTAATTGTGCGTCAGGAGTTGGTATTAGTGGTGA
TGGGTGGTGTGTTTGTCATTGAGACGTTGTCGGTCATTATTCAGGTCACCAGTTTCAAGTTGACCGGCAAGCGGGTGTTT
CGTATGGCGCCGATTCACCATCATTTTGAGTTGAAGGGGTGGCCGGAGCCGCGCGTGATTGTGCGTTTCTGGATTATCTC
GGTGGTGTTGGTGTTGGTTGGTCTTGCGACGTTGAAGGTGCGCTGA

Upstream 100 bases:

>100_bases
CCAGGTGGGGTGCCGCCGCGGGTGCTTGTGAAGGGGTCGCGGGGTAGTGCGATGGACAAAATTGTGGGCGCTCTGTTGTC
GAGTGCGGAGGGCGTAGCGC

Downstream 100 bases:

>100_bases
TGAACGTTTTTATGCCACAGACAGCGCGATTCGAGGTAATGAGAGGTTCTTACGATCCGTGGCTTTTGGGTGCTGCCGTG
GCTTTGGCTTCGCTCGGTGT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MLFEFARWLQQFESLFGLFNYLTFRSILAALTALFLSLWIGPVLIQKLSQFKGGQPIRQDGPKMHFSKAGTPTMGGSLIL
MTVTLSVLLWGDLRNRYVWLVLVVMLAFGAIGWYDDWIKLARRDPNGLKSRWKYLLQSIFGLAAGLFLYFTADVPAAVTF
YIPMFKSIALPLTSISFVAITYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNTLFSSYLKIPTIPGAGDL
IIICAAIAGAGLGFLWFNAYPAMVFMGDIGALALGAVLGTIAVIVRQELVLVVMGGVFVIETLSVIIQVTSFKLTGKRVF
RMAPIHHHFELKGWPEPRVIVRFWIISVVLVLVGLATLKVR

Sequences:

>Translated_361_residues
MLFEFARWLQQFESLFGLFNYLTFRSILAALTALFLSLWIGPVLIQKLSQFKGGQPIRQDGPKMHFSKAGTPTMGGSLIL
MTVTLSVLLWGDLRNRYVWLVLVVMLAFGAIGWYDDWIKLARRDPNGLKSRWKYLLQSIFGLAAGLFLYFTADVPAAVTF
YIPMFKSIALPLTSISFVAITYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNTLFSSYLKIPTIPGAGDL
IIICAAIAGAGLGFLWFNAYPAMVFMGDIGALALGAVLGTIAVIVRQELVLVVMGGVFVIETLSVIIQVTSFKLTGKRVF
RMAPIHHHFELKGWPEPRVIVRFWIISVVLVLVGLATLKVR
>Mature_361_residues
MLFEFARWLQQFESLFGLFNYLTFRSILAALTALFLSLWIGPVLIQKLSQFKGGQPIRQDGPKMHFSKAGTPTMGGSLIL
MTVTLSVLLWGDLRNRYVWLVLVVMLAFGAIGWYDDWIKLARRDPNGLKSRWKYLLQSIFGLAAGLFLYFTADVPAAVTF
YIPMFKSIALPLTSISFVAITYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNTLFSSYLKIPTIPGAGDL
IIICAAIAGAGLGFLWFNAYPAMVFMGDIGALALGAVLGTIAVIVRQELVLVVMGGVFVIETLSVIIQVTSFKLTGKRVF
RMAPIHHHFELKGWPEPRVIVRFWIISVVLVLVGLATLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=59.0027700831025, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_XYLF2 (B2I9B5)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830644.1
- GeneID:   6204025
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1971
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 39729; Mature: 39729

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xed6c514)-; HASH(0xf841bd8)-; HASH(0xe7b03d8)-; HASH(0xf720a2c)-; HASH(0xf7208a0)-; HASH(0xe3cd658)-; HASH(0xf3d2de8)-; HASH(0xf7e9b14)-; HASH(0xf472e6c)-; HASH(0xd66c414)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFEFARWLQQFESLFGLFNYLTFRSILAALTALFLSLWIGPVLIQKLSQFKGGQPIRQD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHC
GPKMHFSKAGTPTMGGSLILMTVTLSVLLWGDLRNRYVWLVLVVMLAFGAIGWYDDWIKL
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ARRDPNGLKSRWKYLLQSIFGLAAGLFLYFTADVPAAVTFYIPMFKSIALPLTSISFVAI
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNTLFSSYLKIPTIPGAGDL
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHH
IIICAAIAGAGLGFLWFNAYPAMVFMGDIGALALGAVLGTIAVIVRQELVLVVMGGVFVI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETLSVIIQVTSFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIISVVLVLVGLATLKV
HHHHHHHHHHHEEECHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
R
H
>Mature Secondary Structure
MLFEFARWLQQFESLFGLFNYLTFRSILAALTALFLSLWIGPVLIQKLSQFKGGQPIRQD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHC
GPKMHFSKAGTPTMGGSLILMTVTLSVLLWGDLRNRYVWLVLVVMLAFGAIGWYDDWIKL
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ARRDPNGLKSRWKYLLQSIFGLAAGLFLYFTADVPAAVTFYIPMFKSIALPLTSISFVAI
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNTLFSSYLKIPTIPGAGDL
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHH
IIICAAIAGAGLGFLWFNAYPAMVFMGDIGALALGAVLGTIAVIVRQELVLVVMGGVFVI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETLSVIIQVTSFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIISVVLVLVGLATLKV
HHHHHHHHHHHEEECHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
R
H

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA