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The map label for this gene is murG [H]

Identifier: 28199735

GI number: 28199735

Start: 2193151

End: 2194245

Strand: Reverse

Name: murG [H]

Synonym: PD1866

Alternate gene names: 28199735

Gene position: 2194245-2193151 (Counterclockwise)

Preceding gene: 28199736

Following gene: 28199734

Centisome position: 87.08

GC content: 54.25

Gene sequence:

>1095_bases
GTGGTCCAATCTGCGGTGACGCACTTTCGCCCCGTCATGATTTTGGCTGGTGGTACCGGTGGTCATATTTTCCCTGGTTT
GGCGGTGGCAGGTGTGTTGCGTGCCCGTGGTGTACCAGTGGTATGGCTGGGCGCAGCCGGAAAAATGGAAACGCATTTAG
TACCAAAGCACGGTATTGAAATACAGACCATTGCCGTTTCCGGTGTGCGTGGTCATGGCATGTTGGCTTTGCTTGGTGCG
CCTGTGCGTGTGTTACCTGCAATTTTTGCTGCCATGCGGGTATTACGTCGGTATCGCCCACGTGTGGTGGTCAGTTTTGG
TGGTTTCGCGGCAGGTCCTGGTGGTATTGCAGCACGTTTGATGGGTCTGCCTCTGATTGTGCACGAGCAGAATCGTGCGC
CTGGAATGACTAATAGGGTTTTGGCACGTGTTGCGAGACGTGTTCTATCTGGTTTTCCGGGCAGTTTTGTTGCTGAGGAG
GTGGTGGGGAATCCAGTGCGTAAGGACATTGCTGCGCTGCCCGCACCAGGAGTACGTTTTGCTGGCCGCAGTGGTCCGGT
GCGCTTGTTAGTGCTTGGGGGCAGTCAGGGGGCACGTGTAATGAATAATGCGTTGCCGGTGGTGTTGCGGGTGTTGTCTG
ATTCTGATGTGGCTGTGGAGGTGCGTCATCAGTGTGGCGAAGCGCTGCGTGCTGAAACGGAGGGTGCCTATGCATATGCA
GGTGTGGCTGCGCGTGTTGAACCGTTTATTAGTGATATGGCTGCAGCGTATTCCTGGGCCGATTTAGTGGTGTGTCGTGC
CGGTGCCTCAACGTTGGCTGAGTTGTGTGCAGCCGGTGTTGGGAGTGTGTTGATACCTTTTCCTGCGGCGGTGGATGATC
ACCAGAGGCGCAATGCGGAATATCTGGTTGCTGCTGGTGCTGCGTTGTTGTTGCAGCAGCAGGACCGTGCATTTTATGTC
TATCTAGAGTCGGTGTTGCGTGATTTGTTGTCTAATCCAATGCGTCGCTTGGCGATGGCTGAGGCTGCACGTGGATTGGC
TAAATCTGATGCTGCCGAGTGTATTGCTGAAATTATTCTTAAGGAATCGATATGA

Upstream 100 bases:

>100_bases
ACGAGGTTGTTGGTGCTCCATTGGCCGCATCGCAGCAGGTGGGGGGAAGTCAGATGCGCTCCCGCGTGGCATCGGTGTTT
GGGAAGGTGCTATGAGCATA

Downstream 100 bases:

>100_bases
GGCGTGGAGTCGTTTCCAAAATGGTTGGGTGTCGTGCTCAAAGTGAGTGCTGTTTGTGATTCGTCGTCTTCAAGACAATG
GCGATTTGATCCGTGCTTTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MVQSAVTHFRPVMILAGGTGGHIFPGLAVAGVLRARGVPVVWLGAAGKMETHLVPKHGIEIQTIAVSGVRGHGMLALLGA
PVRVLPAIFAAMRVLRRYRPRVVVSFGGFAAGPGGIAARLMGLPLIVHEQNRAPGMTNRVLARVARRVLSGFPGSFVAEE
VVGNPVRKDIAALPAPGVRFAGRSGPVRLLVLGGSQGARVMNNALPVVLRVLSDSDVAVEVRHQCGEALRAETEGAYAYA
GVAARVEPFISDMAAAYSWADLVVCRAGASTLAELCAAGVGSVLIPFPAAVDDHQRRNAEYLVAAGAALLLQQQDRAFYV
YLESVLRDLLSNPMRRLAMAEAARGLAKSDAAECIAEIILKESI

Sequences:

>Translated_364_residues
MVQSAVTHFRPVMILAGGTGGHIFPGLAVAGVLRARGVPVVWLGAAGKMETHLVPKHGIEIQTIAVSGVRGHGMLALLGA
PVRVLPAIFAAMRVLRRYRPRVVVSFGGFAAGPGGIAARLMGLPLIVHEQNRAPGMTNRVLARVARRVLSGFPGSFVAEE
VVGNPVRKDIAALPAPGVRFAGRSGPVRLLVLGGSQGARVMNNALPVVLRVLSDSDVAVEVRHQCGEALRAETEGAYAYA
GVAARVEPFISDMAAAYSWADLVVCRAGASTLAELCAAGVGSVLIPFPAAVDDHQRRNAEYLVAAGAALLLQQQDRAFYV
YLESVLRDLLSNPMRRLAMAEAARGLAKSDAAECIAEIILKESI
>Mature_364_residues
MVQSAVTHFRPVMILAGGTGGHIFPGLAVAGVLRARGVPVVWLGAAGKMETHLVPKHGIEIQTIAVSGVRGHGMLALLGA
PVRVLPAIFAAMRVLRRYRPRVVVSFGGFAAGPGGIAARLMGLPLIVHEQNRAPGMTNRVLARVARRVLSGFPGSFVAEE
VVGNPVRKDIAALPAPGVRFAGRSGPVRLLVLGGSQGARVMNNALPVVLRVLSDSDVAVEVRHQCGEALRAETEGAYAYA
GVAARVEPFISDMAAAYSWADLVVCRAGASTLAELCAAGVGSVLIPFPAAVDDHQRRNAEYLVAAGAALLLQQQDRAFYV
YLESVLRDLLSNPMRRLAMAEAARGLAKSDAAECIAEIILKESI

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=350, Percent_Identity=48.8571428571429, Blast_Score=310, Evalue=9e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 38219; Mature: 38219

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQSAVTHFRPVMILAGGTGGHIFPGLAVAGVLRARGVPVVWLGAAGKMETHLVPKHGIE
CCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEECCCCCCE
IQTIAVSGVRGHGMLALLGAPVRVLPAIFAAMRVLRRYRPRVVVSFGGFAAGPGGIAARL
EEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
MGLPLIVHEQNRAPGMTNRVLARVARRVLSGFPGSFVAEEVVGNPVRKDIAALPAPGVRF
HCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCCCCCCEE
AGRSGPVRLLVLGGSQGARVMNNALPVVLRVLSDSDVAVEVRHQCGEALRAETEGAYAYA
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCEEEH
GVAARVEPFISDMAAAYSWADLVVCRAGASTLAELCAAGVGSVLIPFPAAVDDHQRRNAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCHHHCCCC
YLVAAGAALLLQQQDRAFYVYLESVLRDLLSNPMRRLAMAEAARGLAKSDAAECIAEIIL
EEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
KESI
HCCC
>Mature Secondary Structure
MVQSAVTHFRPVMILAGGTGGHIFPGLAVAGVLRARGVPVVWLGAAGKMETHLVPKHGIE
CCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEECCCCCCE
IQTIAVSGVRGHGMLALLGAPVRVLPAIFAAMRVLRRYRPRVVVSFGGFAAGPGGIAARL
EEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
MGLPLIVHEQNRAPGMTNRVLARVARRVLSGFPGSFVAEEVVGNPVRKDIAALPAPGVRF
HCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCCCCCCEE
AGRSGPVRLLVLGGSQGARVMNNALPVVLRVLSDSDVAVEVRHQCGEALRAETEGAYAYA
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCEEEH
GVAARVEPFISDMAAAYSWADLVVCRAGASTLAELCAAGVGSVLIPFPAAVDDHQRRNAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCHHHCCCC
YLVAAGAALLLQQQDRAFYVYLESVLRDLLSNPMRRLAMAEAARGLAKSDAAECIAEIIL
EEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
KESI
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA