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The map label for this gene is int [H]

Identifier: 28198888

GI number: 28198888

Start: 1194756

End: 1195988

Strand: Reverse

Name: int [H]

Synonym: PD0990

Alternate gene names: 28198888

Gene position: 1195988-1194756 (Counterclockwise)

Preceding gene: 28198889

Following gene: 28198887

Centisome position: 47.46

GC content: 58.96

Gene sequence:

>1233_bases
ATGCCGCTCACAGACACCGCCCTGAAAGCCCTCAAGCCCAGAGACAGGATTTATTCCGTGGCTGATGAACGGGGGTTGTC
GGTAGAGGTGTATCCAACAGGGGGGATCGTGTGGCGCTTTCGTTACCGACTGGCGGGCAGGTACGAGAAACTGACGCTGG
GCAAGTATCCCGCCCTGTCGCTCAGGAATGCCCGCCTCAAACGGGATGAGGCGGCGTCGCTGGTGGCTATGGGCACTTCA
CCGGCTCGGCAAAAGCAGCTTGCCAAGGTGACGGCGGCAGATGCAATGACCGTGCGGGACTTTGCCGAGCGGTTTTTTCG
TGAGATTCAATCCAGGGACAGGAAAGACAGCACCATGCCGCGACGGTATCTGGACAAAGACATCCTGCCCTTTGTGGGAG
ACAAGCCCATGCGTGAGGTGACCGCCGAGGAGATACGCTCCCTCATCTGGCGCAAGAAAGAGCAGGGTTTTGACGCGACC
GCGGGGCAGATTCGCGGGGTATTGAAGCGGCTGTGTGATTACGCCGTGACCTGTGGGCTGATGCCTACCAACCCCGTGCT
GGCACTGCCCATGCGCCACGTGTACAAAGCCGTGTCCCGTGACCGCGCACTGTCCCCTGATGAAATTCGCCTTTTCCTGC
GGGCTGTCTGGGCTTCCAGGATCCGGCGGCAATTCAAGCTTGCCCTGCACCTGATCCTGCTGACGATGGTACGCAAATCT
GAATTGCTACTTGCCCGCTGGGATCATGTGCATCTTGACCAGGCCCAATGGCATATCCCTGCAGAGCACTCAAAAACGGG
CAAACCCCATATTGTTTATTTATCACGGCAGGCTGTGGTGTTGTTTGAAGCACTGCGGGTGCTGGCCGGTGGCAGTGCAC
TGGTGATGCCGGGGTCCGGCACGCTGACCAGACCCTTTGCCCATAACGCCCTCAATCACGCCCTGGGCAAAGCCATGCAA
TGGCAGGGGATACACGCCTTCACCATTCATGACCTACGGCGCACGGCATCCACCTGGCTGCACGAACATGGCTGGGCTTC
GGACGTGGTAGAAAAGGCGTTGAATCACAGCATCGGCGGGGTGCGGGGTGTCTATAACCGTGCCGAGTACGCCGATCAGC
GGCGCCAGATGCTGCAATGCTGGGCAGATTTCATTGAAAAGCAGCTAAAAACCGATCATCTCTTGATGGTGTGCCACACC
GAGCTGGACGGGGCGAAACCGGGCACGCCTTAG

Upstream 100 bases:

>100_bases
CTCAGCCCCCAAGGCAGCCAACGTTTTTTATGTCCATCTTTATGTCAATGCAGATAGATGGACGTACTGACCAGGATGAC
ATGGACATAAAGAGGCCCTC

Downstream 100 bases:

>100_bases
CTGGTGCCACATCAAACATGACGACCTGTTCAACAACACACACAGTGGTGCAACCATGCCGCACACTCTTCTGCGACTGC
CCGCCGTCAAGATGGAAACG

Product: phage-related integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MPLTDTALKALKPRDRIYSVADERGLSVEVYPTGGIVWRFRYRLAGRYEKLTLGKYPALSLRNARLKRDEAASLVAMGTS
PARQKQLAKVTAADAMTVRDFAERFFREIQSRDRKDSTMPRRYLDKDILPFVGDKPMREVTAEEIRSLIWRKKEQGFDAT
AGQIRGVLKRLCDYAVTCGLMPTNPVLALPMRHVYKAVSRDRALSPDEIRLFLRAVWASRIRRQFKLALHLILLTMVRKS
ELLLARWDHVHLDQAQWHIPAEHSKTGKPHIVYLSRQAVVLFEALRVLAGGSALVMPGSGTLTRPFAHNALNHALGKAMQ
WQGIHAFTIHDLRRTASTWLHEHGWASDVVEKALNHSIGGVRGVYNRAEYADQRRQMLQCWADFIEKQLKTDHLLMVCHT
ELDGAKPGTP

Sequences:

>Translated_410_residues
MPLTDTALKALKPRDRIYSVADERGLSVEVYPTGGIVWRFRYRLAGRYEKLTLGKYPALSLRNARLKRDEAASLVAMGTS
PARQKQLAKVTAADAMTVRDFAERFFREIQSRDRKDSTMPRRYLDKDILPFVGDKPMREVTAEEIRSLIWRKKEQGFDAT
AGQIRGVLKRLCDYAVTCGLMPTNPVLALPMRHVYKAVSRDRALSPDEIRLFLRAVWASRIRRQFKLALHLILLTMVRKS
ELLLARWDHVHLDQAQWHIPAEHSKTGKPHIVYLSRQAVVLFEALRVLAGGSALVMPGSGTLTRPFAHNALNHALGKAMQ
WQGIHAFTIHDLRRTASTWLHEHGWASDVVEKALNHSIGGVRGVYNRAEYADQRRQMLQCWADFIEKQLKTDHLLMVCHT
ELDGAKPGTP
>Mature_409_residues
PLTDTALKALKPRDRIYSVADERGLSVEVYPTGGIVWRFRYRLAGRYEKLTLGKYPALSLRNARLKRDEAASLVAMGTSP
ARQKQLAKVTAADAMTVRDFAERFFREIQSRDRKDSTMPRRYLDKDILPFVGDKPMREVTAEEIRSLIWRKKEQGFDATA
GQIRGVLKRLCDYAVTCGLMPTNPVLALPMRHVYKAVSRDRALSPDEIRLFLRAVWASRIRRQFKLALHLILLTMVRKSE
LLLARWDHVHLDQAQWHIPAEHSKTGKPHIVYLSRQAVVLFEALRVLAGGSALVMPGSGTLTRPFAHNALNHALGKAMQW
QGIHAFTIHDLRRTASTWLHEHGWASDVVEKALNHSIGGVRGVYNRAEYADQRRQMLQCWADFIEKQLKTDHLLMVCHTE
LDGAKPGTP

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=397, Percent_Identity=34.0050377833753, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1788974, Length=399, Percent_Identity=30.8270676691729, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1788690, Length=392, Percent_Identity=28.5714285714286, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46694; Mature: 46563

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTDTALKALKPRDRIYSVADERGLSVEVYPTGGIVWRFRYRLAGRYEKLTLGKYPALS
CCCCHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCEEEEEHHHHCCCHHEEECCCCCCCH
LRNARLKRDEAASLVAMGTSPARQKQLAKVTAADAMTVRDFAERFFREIQSRDRKDSTMP
HHHHHHCHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RRYLDKDILPFVGDKPMREVTAEEIRSLIWRKKEQGFDATAGQIRGVLKRLCDYAVTCGL
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
MPTNPVLALPMRHVYKAVSRDRALSPDEIRLFLRAVWASRIRRQFKLALHLILLTMVRKS
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLLARWDHVHLDQAQWHIPAEHSKTGKPHIVYLSRQAVVLFEALRVLAGGSALVMPGSG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCC
TLTRPFAHNALNHALGKAMQWQGIHAFTIHDLRRTASTWLHEHGWASDVVEKALNHSIGG
CCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
VRGVYNRAEYADQRRQMLQCWADFIEKQLKTDHLLMVCHTELDGAKPGTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
PLTDTALKALKPRDRIYSVADERGLSVEVYPTGGIVWRFRYRLAGRYEKLTLGKYPALS
CCCHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCEEEEEHHHHCCCHHEEECCCCCCCH
LRNARLKRDEAASLVAMGTSPARQKQLAKVTAADAMTVRDFAERFFREIQSRDRKDSTMP
HHHHHHCHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RRYLDKDILPFVGDKPMREVTAEEIRSLIWRKKEQGFDATAGQIRGVLKRLCDYAVTCGL
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
MPTNPVLALPMRHVYKAVSRDRALSPDEIRLFLRAVWASRIRRQFKLALHLILLTMVRKS
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLLARWDHVHLDQAQWHIPAEHSKTGKPHIVYLSRQAVVLFEALRVLAGGSALVMPGSG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCC
TLTRPFAHNALNHALGKAMQWQGIHAFTIHDLRRTASTWLHEHGWASDVVEKALNHSIGG
CCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
VRGVYNRAEYADQRRQMLQCWADFIEKQLKTDHLLMVCHTELDGAKPGTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]