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The map label for this gene is sodA [H]

Identifier: 28198774

GI number: 28198774

Start: 1082453

End: 1083145

Strand: Reverse

Name: sodA [H]

Synonym: PD0870

Alternate gene names: 28198774

Gene position: 1083145-1082453 (Counterclockwise)

Preceding gene: 28198776

Following gene: 77747669

Centisome position: 42.99

GC content: 51.08

Gene sequence:

>693_bases
TTGCTTGCTTCGTCCCCATCTTTTGCTTCGACACAACCACAAACCGCGCCGTTCACACTACCGCCACTCCCCTACGCTGT
CAGCGCGCTGGAGCCGGCGATTGATACGCAGACCATGACGTTACATCACGACTTCCATCACAAGGCCTACGTAGATAACC
TCAATGCTGCAATCAAGGATATACCGACACTCTCCGGAAAAACGCTGGAGCAACTTCTGGCCATCGCATCCACGTTGCCG
CCAGTGGTACGAAACAACGCCGGCGGCCACTGGAATCACAGCGAGTTCTGGAAGATGATGGCTCCGGTTGGCAAGGGAGG
GAAACCATCGGCAGCGCTGGAAGCACAAATTAAAAAGGACTTTGGTTCACTAGACGCTTTCAAGGAGCGCTTCAACAAAG
CCGCAACAGGTCGTTTCGGCTCGGGCTGGGCTTGGATGATATTGACCAGTAGCGGACTGCAGATCACATCAACACCCAAT
CAGGATAACCCACTGATGGATGTGGTAGAGGTACGCGGTCAGCCATTGCTAGCCTTAGATGTTTGGGAGCATGCGTACTA
TCTCAAGTACAAGTACAAACGTGCTGATTATCTGAACGCTTGGTGGACAGTTGTGAACTGGAATGAGGTCAACCATTTAT
TCGAAGTGGCAAAAAAGGATCAACATAAGCGAATCATTAATCCCCAGCATTAA

Upstream 100 bases:

>100_bases
GGGTGTTAGATTCTGTACTCCATCGCAACCAGATGATCTTTGGAGAGATAGCATGTTTTTTTTGAGACAAGGTCACTTAA
CACTCTGCTTGATTGCTGCA

Downstream 100 bases:

>100_bases
CACTGAACAACACAGAATGATTGCTCTATCTTCAAGCAAACTCGGACTTTCATCCTGAGTCAGACATGCAATCACCAGGC
GGCCGATCATAGTATCAGGC

Product: superoxide dismutase [Mn]

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MLASSPSFASTQPQTAPFTLPPLPYAVSALEPAIDTQTMTLHHDFHHKAYVDNLNAAIKDIPTLSGKTLEQLLAIASTLP
PVVRNNAGGHWNHSEFWKMMAPVGKGGKPSAALEAQIKKDFGSLDAFKERFNKAATGRFGSGWAWMILTSSGLQITSTPN
QDNPLMDVVEVRGQPLLALDVWEHAYYLKYKYKRADYLNAWWTVVNWNEVNHLFEVAKKDQHKRIINPQH

Sequences:

>Translated_230_residues
MLASSPSFASTQPQTAPFTLPPLPYAVSALEPAIDTQTMTLHHDFHHKAYVDNLNAAIKDIPTLSGKTLEQLLAIASTLP
PVVRNNAGGHWNHSEFWKMMAPVGKGGKPSAALEAQIKKDFGSLDAFKERFNKAATGRFGSGWAWMILTSSGLQITSTPN
QDNPLMDVVEVRGQPLLALDVWEHAYYLKYKYKRADYLNAWWTVVNWNEVNHLFEVAKKDQHKRIINPQH
>Mature_230_residues
MLASSPSFASTQPQTAPFTLPPLPYAVSALEPAIDTQTMTLHHDFHHKAYVDNLNAAIKDIPTLSGKTLEQLLAIASTLP
PVVRNNAGGHWNHSEFWKMMAPVGKGGKPSAALEAQIKKDFGSLDAFKERFNKAATGRFGSGWAWMILTSSGLQITSTPN
QDNPLMDVVEVRGQPLLALDVWEHAYYLKYKYKRADYLNAWWTVVNWNEVNHLFEVAKKDQHKRIINPQH

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=229, Percent_Identity=43.2314410480349, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI67782305, Length=229, Percent_Identity=43.2314410480349, Blast_Score=171, Evalue=7e-43,
Organism=Homo sapiens, GI67782309, Length=227, Percent_Identity=37.8854625550661, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI1790342, Length=207, Percent_Identity=49.2753623188406, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1787946, Length=194, Percent_Identity=42.7835051546392, Blast_Score=150, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17506561, Length=204, Percent_Identity=41.1764705882353, Blast_Score=151, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17569479, Length=204, Percent_Identity=41.1764705882353, Blast_Score=150, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6321796, Length=225, Percent_Identity=37.3333333333333, Blast_Score=139, Evalue=5e-34,
Organism=Drosophila melanogaster, GI17136812, Length=203, Percent_Identity=40.8866995073892, Blast_Score=147, Evalue=5e-36,

Paralogues:

None

Copy number: 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 25761; Mature: 25761

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLASSPSFASTQPQTAPFTLPPLPYAVSALEPAIDTQTMTLHHDFHHKAYVDNLNAAIKD
CCCCCCCCCCCCCCCCCEECCCCCHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
IPTLSGKTLEQLLAIASTLPPVVRNNAGGHWNHSEFWKMMAPVGKGGKPSAALEAQIKKD
CCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
FGSLDAFKERFNKAATGRFGSGWAWMILTSSGLQITSTPNQDNPLMDVVEVRGQPLLALD
HCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHCCCCEEEEE
VWEHAYYLKYKYKRADYLNAWWTVVNWNEVNHLFEVAKKDQHKRIINPQH
HHHCEEEEEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLASSPSFASTQPQTAPFTLPPLPYAVSALEPAIDTQTMTLHHDFHHKAYVDNLNAAIKD
CCCCCCCCCCCCCCCCCEECCCCCHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
IPTLSGKTLEQLLAIASTLPPVVRNNAGGHWNHSEFWKMMAPVGKGGKPSAALEAQIKKD
CCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
FGSLDAFKERFNKAATGRFGSGWAWMILTSSGLQITSTPNQDNPLMDVVEVRGQPLLALD
HCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHCCCCEEEEE
VWEHAYYLKYKYKRADYLNAWWTVVNWNEVNHLFEVAKKDQHKRIINPQH
HHHCEEEEEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9074511 [H]