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The map label for this gene is rpiA [H]

Identifier: 28198702

GI number: 28198702

Start: 987117

End: 987764

Strand: Reverse

Name: rpiA [H]

Synonym: PD0797

Alternate gene names: 28198702

Gene position: 987764-987117 (Counterclockwise)

Preceding gene: 28198703

Following gene: 161484692

Centisome position: 39.2

GC content: 52.01

Gene sequence:

>648_bases
ATGAGCGAAGCAAAACGGCGCGCCGCCGAAAAGGCCATCGAATACGTCGAGAACGATATGATTATCGGCGTCGGCACCGG
CTCAACAGTCGCCTACTTCATCGACGCACTAGGACACACCCCAAAACGCATCAAAGGTGCAGTATCCAGCTCCGAACAGA
GCACAGCACATTTAAAACAACACGGAATTGAAGTCCTGGAACTCAATCATACCGGAACACTCCCACTCTATGTGGACGGT
GCAGACGAGTGCGACCCTTACAAACGCCTTATCAAAGGAGGCGGCGCATCATTAACACGCGAGAAGATCATCGCTGAAGC
AAGCAAACAATTCATTTGTATCATCGACCCAAACAAACAGGTAGCAACACTAGGCAAGTTCCCACTACCCATCGAAGTGA
TCCCAATGGCACGCAGCTTGGTTGCAAGGCAAATCATGGCACGTACCGACGGTCAACCAGTATGGCGTGAAGGGGTCATT
ACAGATAACGGCAACGTTATCCTGGATGTACATCACTTATGCATCACCGACCCGGTAAAGCTAGAGCAAGAACTCAATCA
AATCCCAGGGGTCGTCTGCGTCGGCCTGTTCGCCCGTCGCTGTGCGGACCTAGTTATCATCGGCAGCGAACCGCCGCACA
TACTCTGA

Upstream 100 bases:

>100_bases
CTACGAGCCAATGGAAATTGCTACTGTCACTAGAGTGAACTCAACACAGCCAGCCAATGCCTGTGCGCCTTCCCACATCC
CCATCATCATTGATAACCCC

Downstream 100 bases:

>100_bases
ACCCTCCCCCATCGTCTTAAACACTATCCCCATATAATGCATAAACGATCTATAGCAGTGAAAAGTACGCGCTGCGTTCA
ATGTCAAATCCCTGCAAAGC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSEAKRRAAEKAIEYVENDMIIGVGTGSTVAYFIDALGHTPKRIKGAVSSSEQSTAHLKQHGIEVLELNHTGTLPLYVDG
ADECDPYKRLIKGGGASLTREKIIAEASKQFICIIDPNKQVATLGKFPLPIEVIPMARSLVARQIMARTDGQPVWREGVI
TDNGNVILDVHHLCITDPVKLEQELNQIPGVVCVGLFARRCADLVIIGSEPPHIL

Sequences:

>Translated_215_residues
MSEAKRRAAEKAIEYVENDMIIGVGTGSTVAYFIDALGHTPKRIKGAVSSSEQSTAHLKQHGIEVLELNHTGTLPLYVDG
ADECDPYKRLIKGGGASLTREKIIAEASKQFICIIDPNKQVATLGKFPLPIEVIPMARSLVARQIMARTDGQPVWREGVI
TDNGNVILDVHHLCITDPVKLEQELNQIPGVVCVGLFARRCADLVIIGSEPPHIL
>Mature_214_residues
SEAKRRAAEKAIEYVENDMIIGVGTGSTVAYFIDALGHTPKRIKGAVSSSEQSTAHLKQHGIEVLELNHTGTLPLYVDGA
DECDPYKRLIKGGGASLTREKIIAEASKQFICIIDPNKQVATLGKFPLPIEVIPMARSLVARQIMARTDGQPVWREGVIT
DNGNVILDVHHLCITDPVKLEQELNQIPGVVCVGLFARRCADLVIIGSEPPHIL

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=211, Percent_Identity=36.4928909952607, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1789280, Length=207, Percent_Identity=58.4541062801932, Blast_Score=246, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17551758, Length=223, Percent_Identity=35.8744394618834, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6324669, Length=220, Percent_Identity=33.1818181818182, Blast_Score=101, Evalue=9e-23,
Organism=Drosophila melanogaster, GI281364072, Length=205, Percent_Identity=32.1951219512195, Blast_Score=91, Evalue=8e-19,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23380; Mature: 23249

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAKRRAAEKAIEYVENDMIIGVGTGSTVAYFIDALGHTPKRIKGAVSSSEQSTAHLKQ
CCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
HGIEVLELNHTGTLPLYVDGADECDPYKRLIKGGGASLTREKIIAEASKQFICIIDPNKQ
CCCEEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCC
VATLGKFPLPIEVIPMARSLVARQIMARTDGQPVWREGVITDNGNVILDVHHLCITDPVK
EEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHCCEEECCCCEEEEEEHHHCCCHHH
LEQELNQIPGVVCVGLFARRCADLVIIGSEPPHIL
HHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCCCC
>Mature Secondary Structure 
SEAKRRAAEKAIEYVENDMIIGVGTGSTVAYFIDALGHTPKRIKGAVSSSEQSTAHLKQ
CHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
HGIEVLELNHTGTLPLYVDGADECDPYKRLIKGGGASLTREKIIAEASKQFICIIDPNKQ
CCCEEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCC
VATLGKFPLPIEVIPMARSLVARQIMARTDGQPVWREGVITDNGNVILDVHHLCITDPVK
EEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHCCEEECCCCEEEEEEHHHCCCHHH
LEQELNQIPGVVCVGLFARRCADLVIIGSEPPHIL
HHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]