Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 28198491

GI number: 28198491

Start: 712864

End: 713976

Strand: Reverse

Name: aroB [H]

Synonym: PD0581

Alternate gene names: 28198491

Gene position: 713976-712864 (Counterclockwise)

Preceding gene: 28198492

Following gene: 28198490

Centisome position: 28.33

GC content: 59.66

Gene sequence:

>1113_bases
ATGACCACTCCCACACCACTGCGCAGCGTCACCGTCAACACCCCCCCCCCCTATACCATCGCCATTGGTCCCGGCCTATT
GCACGATCCTCCACGCCTGGCCGCCACCATCCGCGGCAGACATGCACTCATTCTCAGTGATTCTGAAGTCGCCCCCCGTT
ATGCCGCACAACTGCATGAAACGCTACTGCGCGCCCGTCCCGATCTACACCTCAACGTATTCACCCTGCCAGCCGGCGAA
ACATCCAAGTCCCTAGAGAACTTCGGCGCCGCAATCGCCCAACTCGCCACACTGGGCGCCACGCGTGATGCCTGCCTCTT
TGCACTCGGCGGCGGCGTCATCGGGGATCTGGCCGGCTTTACCGCCGCCTGCTGGATGCGTGGCATCGACTACGTACAAG
TGCCAACCACCTTATTGGCGATGGTCGACTCTTCCGTCGGCGGCAAAACCGCCGTAGACATCCCCCAGGGTAAAAACATG
GTCGGTGCCTTCCATCCGCCACGTGCAGTGATCGCCGATACCGACACCCTTGCCACACTCCCGCTACGGGAACTACGCGC
TGGTCTGAGCGAAGTCATCAAATACGGCGCAATCCGCGACCCCGTATTCTTCCACTGGCTCCAAACCACACGCGAAGCAC
TTCTAGCACGTGACCCCGCCGCACTGGCCCAAGCAATCGCACGTAGCTGCGAACACAAAGCCGATATTGTCGGACGTGAC
CCACTGGAAAAAGGGGAACGCGTCCTGCTCAATCTCGGTCATACCTTCGGCCACGCCATAGAAACAACACAGGGCTACAG
CACACCAGGAAGCAACAACCTCAACCACGGTGAAGCCGTCGCCGTCGGCATGGTACTTGCCGCACGCTTGTCAAACACAT
TAGGTCTGGCACCCGCAGAAGACACCGAGACACTGAAAAACCTACTGGATGCCTACGGCTTGCCCACTGTCCTGCCCTCA
GGTCTAACACCTGAAATGCTCCTGGAGCGTATGCGCCTGGACAAAAAAAACATTGCCGGCCGCTTACGCTTGGTCCTATG
GCGCGGTATTGGCCACGCCGAAGCCGTCCCCGACGTTGATGAAGCAGCCGTGCGACAGATCCTGGCCAACTAA

Upstream 100 bases:

>100_bases
CAGATATGATTGTGACCACCGACCACATGTCCCCTAACACAGCCACCGCCCAGCTCATTCTGGACTTAACAGCCCACTGG
CAGAAATCAAGCAACACCGC

Downstream 100 bases:

>100_bases
GCCAATCAACATACGACCACCAAGCCACCAAACCGACGCCCCCATTGATGTGCATCACACCATCACTGACACCCCAACCC
CACCAGATGCATCCCCACAA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTTPTPLRSVTVNTPPPYTIAIGPGLLHDPPRLAATIRGRHALILSDSEVAPRYAAQLHETLLRARPDLHLNVFTLPAGE
TSKSLENFGAAIAQLATLGATRDACLFALGGGVIGDLAGFTAACWMRGIDYVQVPTTLLAMVDSSVGGKTAVDIPQGKNM
VGAFHPPRAVIADTDTLATLPLRELRAGLSEVIKYGAIRDPVFFHWLQTTREALLARDPAALAQAIARSCEHKADIVGRD
PLEKGERVLLNLGHTFGHAIETTQGYSTPGSNNLNHGEAVAVGMVLAARLSNTLGLAPAEDTETLKNLLDAYGLPTVLPS
GLTPEMLLERMRLDKKNIAGRLRLVLWRGIGHAEAVPDVDEAAVRQILAN

Sequences:

>Translated_370_residues
MTTPTPLRSVTVNTPPPYTIAIGPGLLHDPPRLAATIRGRHALILSDSEVAPRYAAQLHETLLRARPDLHLNVFTLPAGE
TSKSLENFGAAIAQLATLGATRDACLFALGGGVIGDLAGFTAACWMRGIDYVQVPTTLLAMVDSSVGGKTAVDIPQGKNM
VGAFHPPRAVIADTDTLATLPLRELRAGLSEVIKYGAIRDPVFFHWLQTTREALLARDPAALAQAIARSCEHKADIVGRD
PLEKGERVLLNLGHTFGHAIETTQGYSTPGSNNLNHGEAVAVGMVLAARLSNTLGLAPAEDTETLKNLLDAYGLPTVLPS
GLTPEMLLERMRLDKKNIAGRLRLVLWRGIGHAEAVPDVDEAAVRQILAN
>Mature_369_residues
TTPTPLRSVTVNTPPPYTIAIGPGLLHDPPRLAATIRGRHALILSDSEVAPRYAAQLHETLLRARPDLHLNVFTLPAGET
SKSLENFGAAIAQLATLGATRDACLFALGGGVIGDLAGFTAACWMRGIDYVQVPTTLLAMVDSSVGGKTAVDIPQGKNMV
GAFHPPRAVIADTDTLATLPLRELRAGLSEVIKYGAIRDPVFFHWLQTTREALLARDPAALAQAIARSCEHKADIVGRDP
LEKGERVLLNLGHTFGHAIETTQGYSTPGSNNLNHGEAVAVGMVLAARLSNTLGLAPAEDTETLKNLLDAYGLPTVLPSG
LTPEMLLERMRLDKKNIAGRLRLVLWRGIGHAEAVPDVDEAAVRQILAN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=353, Percent_Identity=45.3257790368272, Blast_Score=264, Evalue=6e-72,
Organism=Saccharomyces cerevisiae, GI6320332, Length=339, Percent_Identity=36.283185840708, Blast_Score=180, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39409; Mature: 39278

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPTPLRSVTVNTPPPYTIAIGPGLLHDPPRLAATIRGRHALILSDSEVAPRYAAQLHE
CCCCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
TLLRARPDLHLNVFTLPAGETSKSLENFGAAIAQLATLGATRDACLFALGGGVIGDLAGF
HHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHH
TAACWMRGIDYVQVPTTLLAMVDSSVGGKTAVDIPQGKNMVGAFHPPRAVIADTDTLATL
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCCCEEEECCCHHHHC
PLRELRAGLSEVIKYGAIRDPVFFHWLQTTREALLARDPAALAQAIARSCEHKADIVGRD
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
PLEKGERVLLNLGHTFGHAIETTQGYSTPGSNNLNHGEAVAVGMVLAARLSNTLGLAPAE
CHHHCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
DTETLKNLLDAYGLPTVLPSGLTPEMLLERMRLDKKNIAGRLRLVLWRGIGHAEAVPDVD
HHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHCCHHHHHHHHHEEHHHCCCCCCCCCCHH
EAAVRQILAN
HHHHHHHHCC
>Mature Secondary Structure 
TTPTPLRSVTVNTPPPYTIAIGPGLLHDPPRLAATIRGRHALILSDSEVAPRYAAQLHE
CCCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
TLLRARPDLHLNVFTLPAGETSKSLENFGAAIAQLATLGATRDACLFALGGGVIGDLAGF
HHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHH
TAACWMRGIDYVQVPTTLLAMVDSSVGGKTAVDIPQGKNMVGAFHPPRAVIADTDTLATL
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCCCEEEECCCHHHHC
PLRELRAGLSEVIKYGAIRDPVFFHWLQTTREALLARDPAALAQAIARSCEHKADIVGRD
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
PLEKGERVLLNLGHTFGHAIETTQGYSTPGSNNLNHGEAVAVGMVLAARLSNTLGLAPAE
CHHHCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
DTETLKNLLDAYGLPTVLPSGLTPEMLLERMRLDKKNIAGRLRLVLWRGIGHAEAVPDVD
HHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHCCHHHHHHHHHEEHHHCCCCCCCCCCHH
EAAVRQILAN
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]