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The map label for this gene is dcm [H]

Identifier: 28198487

GI number: 28198487

Start: 708396

End: 709463

Strand: Reverse

Name: dcm [H]

Synonym: PD0577

Alternate gene names: 28198487

Gene position: 709463-708396 (Counterclockwise)

Preceding gene: 28198488

Following gene: 28198485

Centisome position: 28.16

GC content: 57.21

Gene sequence:

>1068_bases
ATGAGCCGTCATCCACGACGCCCCAAGAACATCCCCAACATTGTGGGCGTTGATCTTTTCTGCGGTGTGGGCGGCTTAAC
CCATGGCCTGGCTCGCGGTGGCATTTCAGTCGCCGCAGGCATCGACATTGATCCAAACTGTCAATTCCCCTTCGAGGCGA
ACAATGCTGCCTTGTTTCTTGAATGCGATGTCGCAAGGCTGAAAGCCGCAGCGGTGAGGGGCTTCTATCAAGCCGCCGAC
ATCACCTTGCTTGCCGGATGCGCACCATGCCAACCGTTCTCGGCTTACAGCCGTAGTCGGCGGAATAACGCGTATGCCTC
GCAGTGGCCCTTGGTGCTTGCCTTCGCCCGGCTCGTCAAACAACTCAAGCCGGACCTAGTGACGATGGAGAATGTGCCGC
AGCTTGTAAATCACACGGTCTTTCAACAGTTTCTAAAGAGTCTTTCTGGCTATAAGACGTGGTGGCATATCGTGGAATGT
GCATCCATCGGTGTTCCGCAGACACGTAAGCGCTTGGTGCTACTTGCATCCAGGCTAGGTTCTCAAGGACTGGAACTTTC
ACAGCAGCATGTTCCAAGGATGACGGTCCGTGAGGCCATTGGCTCTCTTCCTCCCATTCATGCAGGGGAGCGTGATCCTC
AAGACGCGCTGCACACCGCCGCGTCTTTAAGTGCTTTGAACATGTCGAGGATTCGGGCGTCGCGCCCTGGAGGCACGTGG
CGTGATTGGCCCGCAGCACTGCGGGCAGCGTGCCATTGCAAAGACACTGGGGCCACCTATCCAAGCGTCTACGGTCGTAT
GGAATGGGATCAGCCAGCACCGACCATCACCACCCAATGTTTTGGTTACGGCAACGGACGGTTTGGGCATCCGGAGCAAG
ATCGCGCTATCTCACTGCGAGAGGCAGCAATACTCCAAACGTTCCCAAAGTCTTATCGGTTCGCCCCACCGGGCGCTCCG
ATCACGGTGAATACCATGGGACGTCTGATCGGGAATGCGGTACCAGTGCGGCTGGGCGAGGTCATCGCTCGTTCACTCGT
CAGGCATGTGCAGGGGTACATGGGCTGA

Upstream 100 bases:

>100_bases
CACTCAAGGAGAAGACCGTTGATTACCTTGACGACGTGGTGGACCACTTCGCCAGATACATTGATCGCTTTGAATATCTT
GCCCCGGAGAAGCGTCCTGC

Downstream 100 bases:

>100_bases
CATCACAGCAAGCAGCATCCCTGTGTCAGCCAAGAACACCTCATCGACGCGCTAACGCGATCAAACACCGGCAAGATCAG
GTGAAACAGCAGTAGATCAA

Product: site-specific DNA-methyltransferase

Products: NA

Alternate protein names: M.HgiDII; Cytosine-specific methyltransferase HgiDII [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSRHPRRPKNIPNIVGVDLFCGVGGLTHGLARGGISVAAGIDIDPNCQFPFEANNAALFLECDVARLKAAAVRGFYQAAD
ITLLAGCAPCQPFSAYSRSRRNNAYASQWPLVLAFARLVKQLKPDLVTMENVPQLVNHTVFQQFLKSLSGYKTWWHIVEC
ASIGVPQTRKRLVLLASRLGSQGLELSQQHVPRMTVREAIGSLPPIHAGERDPQDALHTAASLSALNMSRIRASRPGGTW
RDWPAALRAACHCKDTGATYPSVYGRMEWDQPAPTITTQCFGYGNGRFGHPEQDRAISLREAAILQTFPKSYRFAPPGAP
ITVNTMGRLIGNAVPVRLGEVIARSLVRHVQGYMG

Sequences:

>Translated_355_residues
MSRHPRRPKNIPNIVGVDLFCGVGGLTHGLARGGISVAAGIDIDPNCQFPFEANNAALFLECDVARLKAAAVRGFYQAAD
ITLLAGCAPCQPFSAYSRSRRNNAYASQWPLVLAFARLVKQLKPDLVTMENVPQLVNHTVFQQFLKSLSGYKTWWHIVEC
ASIGVPQTRKRLVLLASRLGSQGLELSQQHVPRMTVREAIGSLPPIHAGERDPQDALHTAASLSALNMSRIRASRPGGTW
RDWPAALRAACHCKDTGATYPSVYGRMEWDQPAPTITTQCFGYGNGRFGHPEQDRAISLREAAILQTFPKSYRFAPPGAP
ITVNTMGRLIGNAVPVRLGEVIARSLVRHVQGYMG
>Mature_354_residues
SRHPRRPKNIPNIVGVDLFCGVGGLTHGLARGGISVAAGIDIDPNCQFPFEANNAALFLECDVARLKAAAVRGFYQAADI
TLLAGCAPCQPFSAYSRSRRNNAYASQWPLVLAFARLVKQLKPDLVTMENVPQLVNHTVFQQFLKSLSGYKTWWHIVECA
SIGVPQTRKRLVLLASRLGSQGLELSQQHVPRMTVREAIGSLPPIHAGERDPQDALHTAASLSALNMSRIRASRPGGTWR
DWPAALRAACHCKDTGATYPSVYGRMEWDQPAPTITTQCFGYGNGRFGHPEQDRAISLREAAILQTFPKSYRFAPPGAPI
TVNTMGRLIGNAVPVRLGEVIARSLVRHVQGYMG

Specific function: This methylase recognizes the double-stranded sequence GTCGAC, causes specific methylation on C-? on both strands and protects the DNA from cleavage by the HgiDII endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 38788; Mature: 38657

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00095 C5_MTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRHPRRPKNIPNIVGVDLFCGVGGLTHGLARGGISVAAGIDIDPNCQFPFEANNAALFL
CCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCEEEEE
ECDVARLKAAAVRGFYQAADITLLAGCAPCQPFSAYSRSRRNNAYASQWPLVLAFARLVK
ECCHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QLKPDLVTMENVPQLVNHTVFQQFLKSLSGYKTWWHIVECASIGVPQTRKRLVLLASRLG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
SQGLELSQQHVPRMTVREAIGSLPPIHAGERDPQDALHTAASLSALNMSRIRASRPGGTW
CCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RDWPAALRAACHCKDTGATYPSVYGRMEWDQPAPTITTQCFGYGNGRFGHPEQDRAISLR
HHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHHEEECCCCCCCCCCCCHHHHHH
EAAILQTFPKSYRFAPPGAPITVNTMGRLIGNAVPVRLGEVIARSLVRHVQGYMG
HHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRHPRRPKNIPNIVGVDLFCGVGGLTHGLARGGISVAAGIDIDPNCQFPFEANNAALFL
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCEEEEE
ECDVARLKAAAVRGFYQAADITLLAGCAPCQPFSAYSRSRRNNAYASQWPLVLAFARLVK
ECCHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QLKPDLVTMENVPQLVNHTVFQQFLKSLSGYKTWWHIVECASIGVPQTRKRLVLLASRLG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
SQGLELSQQHVPRMTVREAIGSLPPIHAGERDPQDALHTAASLSALNMSRIRASRPGGTW
CCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RDWPAALRAACHCKDTGATYPSVYGRMEWDQPAPTITTQCFGYGNGRFGHPEQDRAISLR
HHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHHEEECCCCCCCCCCCCHHHHHH
EAAILQTFPKSYRFAPPGAPITVNTMGRLIGNAVPVRLGEVIARSLVRHVQGYMG
HHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1937045; 7607523 [H]