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The map label for this gene is frr [H]

Identifier: 28198252

GI number: 28198252

Start: 424504

End: 425061

Strand: Reverse

Name: frr [H]

Synonym: PD0331

Alternate gene names: 28198252

Gene position: 425061-424504 (Counterclockwise)

Preceding gene: 28198253

Following gene: 28198251

Centisome position: 16.87

GC content: 49.82

Gene sequence:

>558_bases
ATGCTCAACCAAATCAAACAAGACGCTCAGGATCGCATGACAAAGAGCATTGACGCTCTACGCAACTCCCTGGCATCTGT
ACGTACTGGCCGGGCTTCGCCATCACTATTGGATGGCATCAAAATCAAGGCTTACGGTACCGATACACCATTGAATCAGG
TCGCCAGCATCAGTGTCTCAGAAGGACGCTCATTGGTCATCACGGTGTTCGACAAAAATATGTCCAAGGACGTTGAGAAA
GCAATTTATGCTTCCGACCTTGGCCTGACACCAACCGTTGTTGGCACATTGATCCGCCTCAACCTGCCACCACTCACTGA
GGAGCGCCGTAAGGAACTCACAAAAGTCGTGCACAGCGAGGGAGAGGACACCAAAGTCGCAATCCGCAATATCCGCCGCG
ACGCCAATCAGCAGATTAAGGATATGCTAAAGAGCAAGGAAATCACTGAAGACGAAGTACGCCACGGTGAAGAAGACATC
CAGAAGCTGACCGATAAAGCAATCAAAAGCGTGGATGAGGTAGTCAAGTCCAAAGAACAGGAATTGATGACGGTCTGA

Upstream 100 bases:

>100_bases
GAATTCACCAGAAAAAGAGCTTGGATCACCCCCTCAGCACCACAAGCACCAGTCCCAGCTATAATCGGTCAACTACGCTT
TATCAATGAACATTCAGGCG

Downstream 100 bases:

>100_bases
AGATGCAGATCAACACCATACCAGTCAATCCCACACTTCCCCGCCACATAGCCATCATCATGGATGGTAACGGGCGCTGG
GCAGAACGCCGATCACGGCC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLNQIKQDAQDRMTKSIDALRNSLASVRTGRASPSLLDGIKIKAYGTDTPLNQVASISVSEGRSLVITVFDKNMSKDVEK
AIYASDLGLTPTVVGTLIRLNLPPLTEERRKELTKVVHSEGEDTKVAIRNIRRDANQQIKDMLKSKEITEDEVRHGEEDI
QKLTDKAIKSVDEVVKSKEQELMTV

Sequences:

>Translated_185_residues
MLNQIKQDAQDRMTKSIDALRNSLASVRTGRASPSLLDGIKIKAYGTDTPLNQVASISVSEGRSLVITVFDKNMSKDVEK
AIYASDLGLTPTVVGTLIRLNLPPLTEERRKELTKVVHSEGEDTKVAIRNIRRDANQQIKDMLKSKEITEDEVRHGEEDI
QKLTDKAIKSVDEVVKSKEQELMTV
>Mature_185_residues
MLNQIKQDAQDRMTKSIDALRNSLASVRTGRASPSLLDGIKIKAYGTDTPLNQVASISVSEGRSLVITVFDKNMSKDVEK
AIYASDLGLTPTVVGTLIRLNLPPLTEERRKELTKVVHSEGEDTKVAIRNIRRDANQQIKDMLKSKEITEDEVRHGEEDI
QKLTDKAIKSVDEVVKSKEQELMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=55.7377049180328, Blast_Score=215, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=25.2873563218391, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20630; Mature: 20630

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNQIKQDAQDRMTKSIDALRNSLASVRTGRASPSLLDGIKIKAYGTDTPLNQVASISVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCHHHHHHHHHC
EGRSLVITVFDKNMSKDVEKAIYASDLGLTPTVVGTLIRLNLPPLTEERRKELTKVVHSE
CCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
GEDTKVAIRNIRRDANQQIKDMLKSKEITEDEVRHGEEDIQKLTDKAIKSVDEVVKSKEQ
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMTV
HHCCC
>Mature Secondary Structure
MLNQIKQDAQDRMTKSIDALRNSLASVRTGRASPSLLDGIKIKAYGTDTPLNQVASISVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCHHHHHHHHHC
EGRSLVITVFDKNMSKDVEKAIYASDLGLTPTVVGTLIRLNLPPLTEERRKELTKVVHSE
CCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
GEDTKVAIRNIRRDANQQIKDMLKSKEITEDEVRHGEEDIQKLTDKAIKSVDEVVKSKEQ
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMTV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]