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The map label for this gene is hemH

Identifier: 28198097

GI number: 28198097

Start: 212873

End: 213799

Strand: Reverse

Name: hemH

Synonym: PD0166

Alternate gene names: 28198097

Gene position: 213799-212873 (Counterclockwise)

Preceding gene: 28198100

Following gene: 28198096

Centisome position: 8.48

GC content: 55.02

Gene sequence:

>927_bases
TTGCTGACTACGCTGTTGCAATCCGATCTTCCCGGTCTGCCATTGCGTCACTGCGGCAAAGTCCGTGATGTATTCGACAT
TCCACGCAAACGCTTGCCGGTCGACACGCGATCTGGTGAGTACCTGCTCATCGTCGCCACGGACCGCCTCTCGGCATTCG
ATGTCGTCTTACCCGATCCGATCCCCGGGAAAGGCGAGATACTGTGCCAAATCTCCAACTTTTGGTTTCAGAAAACCGAG
CACTTGATGCCGAACCACTTGACCGGCATCAACGTCGCTAGCGTACTCCCTGACGGCATTGACAAAACGCTCTACATACA
GCGTGCCGTAGTGACAAAGAAACTCAAACCGGTAGGGATTGAAGCAATCGCACGTGGCTATTTGATCGGCAGCGGCTGGA
AGGATTACCAACGCACCGGGAAAGTCAGCGGCATTCAGCTCCCCGACGGCCTGCAAGAAGCCGAGAAATTACCTGACCCC
ATCTTCACCCCATCGACCAAAGCAGCAGTTGGCCACCACGACGAAAACATCGACTTTGACACAACCGTCAAGATGGTCGG
CGCTGAACTCGCCGAACGTGTGCGGGACGCCACGCTGCGCATTTACCACTTCGCCGCCAAGTACGCAGCCGAATGCGGCA
TCCTACTCGCCGATACCAAGTTGGAGTTTGGCACTGACATTGATGGCCGCCTCTATGTGATGGACGAAATGCTCACTCCA
GACTCATCGCGCTACTGGCCAATCGACGAATATCAAGTCGGCACTAGCCCACCAAGTTACGACAAGCAACTCGTACGCAA
CTACCTGGAAACACTGGACTGGGACAAAACCGCACCAGGCCCAACACTGCCACAAGACATCATCGACCGTACCCGGGCCA
AGTACACCGAAGCGCTACAACGACTAGCAGGAATCAACATTGATTGA

Upstream 100 bases:

>100_bases
TAAAATCACCGTACACTAGGAGCTTCGTCTACCGTGGGGGTTTTCCATCGCTCCACGGATATATGGGGTACCACGACGCC
ACTTGAATTAGGAGCATCTC

Downstream 100 bases:

>100_bases
CTCCTGTATTCACTCGTCCATATCAAAGCCCCTACCGCACGAGAAGCCACACCATGACACACCGCTGACGTACTGCGGCC
CCAGATGACTCCAAACCATG

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MLTTLLQSDLPGLPLRHCGKVRDVFDIPRKRLPVDTRSGEYLLIVATDRLSAFDVVLPDPIPGKGEILCQISNFWFQKTE
HLMPNHLTGINVASVLPDGIDKTLYIQRAVVTKKLKPVGIEAIARGYLIGSGWKDYQRTGKVSGIQLPDGLQEAEKLPDP
IFTPSTKAAVGHHDENIDFDTTVKMVGAELAERVRDATLRIYHFAAKYAAECGILLADTKLEFGTDIDGRLYVMDEMLTP
DSSRYWPIDEYQVGTSPPSYDKQLVRNYLETLDWDKTAPGPTLPQDIIDRTRAKYTEALQRLAGINID

Sequences:

>Translated_308_residues
MLTTLLQSDLPGLPLRHCGKVRDVFDIPRKRLPVDTRSGEYLLIVATDRLSAFDVVLPDPIPGKGEILCQISNFWFQKTE
HLMPNHLTGINVASVLPDGIDKTLYIQRAVVTKKLKPVGIEAIARGYLIGSGWKDYQRTGKVSGIQLPDGLQEAEKLPDP
IFTPSTKAAVGHHDENIDFDTTVKMVGAELAERVRDATLRIYHFAAKYAAECGILLADTKLEFGTDIDGRLYVMDEMLTP
DSSRYWPIDEYQVGTSPPSYDKQLVRNYLETLDWDKTAPGPTLPQDIIDRTRAKYTEALQRLAGINID
>Mature_308_residues
MLTTLLQSDLPGLPLRHCGKVRDVFDIPRKRLPVDTRSGEYLLIVATDRLSAFDVVLPDPIPGKGEILCQISNFWFQKTE
HLMPNHLTGINVASVLPDGIDKTLYIQRAVVTKKLKPVGIEAIARGYLIGSGWKDYQRTGKVSGIQLPDGLQEAEKLPDP
IFTPSTKAAVGHHDENIDFDTTVKMVGAELAERVRDATLRIYHFAAKYAAECGILLADTKLEFGTDIDGRLYVMDEMLTP
DSSRYWPIDEYQVGTSPPSYDKQLVRNYLETLDWDKTAPGPTLPQDIIDRTRAKYTEALQRLAGINID

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=311, Percent_Identity=42.443729903537, Blast_Score=241, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PUR7_XYLF2 (B2I6R9)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001828885.1
- ProteinModelPortal:   B2I6R9
- SMR:   B2I6R9
- GeneID:   6203495
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0154
- HOGENOM:   HBG555040
- OMA:   LTLMDEV
- ProtClustDB:   PRK13961
- HAMAP:   MF_00137
- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236
- Gene3D:   G3DSA:3.30.470.20
- PANTHER:   PTHR11609
- TIGRFAMs:   TIGR00081

Pfam domain/function: PF01259 SAICAR_synt

EC number: =6.3.2.6

Molecular weight: Translated: 34437; Mature: 34437

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01057 SAICAR_SYNTHETASE_1; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTLLQSDLPGLPLRHCGKVRDVFDIPRKRLPVDTRSGEYLLIVATDRLSAFDVVLPDP
CCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEEEECCCCEEEEECCCC
IPGKGEILCQISNFWFQKTEHLMPNHLTGINVASVLPDGIDKTLYIQRAVVTKKLKPVGI
CCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCH
EAIARGYLIGSGWKDYQRTGKVSGIQLPDGLQEAEKLPDPIFTPSTKAAVGHHDENIDFD
HHHHHCCEECCCCHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
TTVKMVGAELAERVRDATLRIYHFAAKYAAECGILLADTKLEFGTDIDGRLYVMDEMLTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEECCCCC
DSSRYWPIDEYQVGTSPPSYDKQLVRNYLETLDWDKTAPGPTLPQDIIDRTRAKYTEALQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLAGINID
HHHCCCCC
>Mature Secondary Structure
MLTTLLQSDLPGLPLRHCGKVRDVFDIPRKRLPVDTRSGEYLLIVATDRLSAFDVVLPDP
CCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEEEECCCCEEEEECCCC
IPGKGEILCQISNFWFQKTEHLMPNHLTGINVASVLPDGIDKTLYIQRAVVTKKLKPVGI
CCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCH
EAIARGYLIGSGWKDYQRTGKVSGIQLPDGLQEAEKLPDPIFTPSTKAAVGHHDENIDFD
HHHHHCCEECCCCHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
TTVKMVGAELAERVRDATLRIYHFAAKYAAECGILLADTKLEFGTDIDGRLYVMDEMLTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEEEECCCCC
DSSRYWPIDEYQVGTSPPSYDKQLVRNYLETLDWDKTAPGPTLPQDIIDRTRAKYTEALQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLAGINID
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA