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The map label for this gene is nrfE [H]

Identifier: 27366300

GI number: 27366300

Start: 3096042

End: 3097961

Strand: Reverse

Name: nrfE [H]

Synonym: VV1_3031

Alternate gene names: 27366300

Gene position: 3097961-3096042 (Counterclockwise)

Preceding gene: 27366301

Following gene: 27366299

Centisome position: 94.4

GC content: 49.22

Gene sequence:

>1920_bases
ATGGAGGCAGAACTGGGCCTAATTTGCCTGATTTTGGCGGCAGTCGGCAGTAGTTTCGCAGTGATACTGCACGCCATGAA
TCGACTGTTATCGAAGCAAACACCCCTCGCATTGATGTTGGGTTGTGGGTATTTAGTGGCGCTCAGCTCTGCTTTTTCCT
TGTTGTATCTGATTCTTGCTTTTGTTGCCGATGATTTCGCATTGGCTTATGTGGCAAGCCATTCCAACAGCCAATTACCC
GTGATCTTTAAAATTGCGGCAAGTTGGGGAGGACATCAAGGCTCGATGCTGTTTTGGGTCGTCACCTTAAGTTTGTGGGC
TTGCTTGATTCGATCTCGTGATGAGTTCTCATCGCAGTACAAAGCCGATTATATTGCGGTAATGCTCATGCTGACCGCCA
TTTTCGCGTGGTTTACTCTGTTAACCTCGAACCCATTCGAGTACGCGCCATCACTGGCCAGTGATGGACGCGATCTCAAC
CCAATGTTGCAAGATGTTGGGCTCATTTTGCATCCCCCGCTACTGTACCTTGGTTATGTCGGTTTCGCTTCTATCCTAGC
GTTGGGCGTGGCGGCGTTGTTACAGCCATCGGCCATCCATCATTGGTTTCAGGCAGGCCGTGACTGGGCGATGGTTGCGT
GGGGCTTTCTCACCTTAGGCATTATTGTCGGCTCCTGGTGGGCATACAATGAATTAGGCTGGGGAGGTTGGTGGTTCTGG
GATCCAGTTGAAAATGCCTCTTTGCTACCTTGGTTAACAGCAACCGCCTTGTTACACACACTTGTTCAATCAAAGCGGCA
AGGTGGGGTCAATAAATCCAGCTATATGCTCGCGTTTTTGACCTTCGGTTTCAGTGTTCTCGGTACTTTTATTGTCCGCT
CGGGGATTTTGACATCGGTACATGCGTTTGCCGTGGATCCAACCAAAGGTATTGTACTTTTGCTGGTCATGGCGTTCATT
TTTCTACTCACTTTTGCATTATTGATCCTCAAAAGCGATAGCATCCCCGCTAAAGGCATTACCCATTGGCTAAGTCGCCA
ATACCTTACGCTGGTGGCGATGGGTTTGTTACTGATCGCAACCAGTACCGTGTTCCTTGGCACCTTCTACCCAATGATTT
ATGAGCTGCTGCGGCTTGGGAGCATCTCAGTGGGCGCTCCGTATTTCAATACAATGATTGCGCCATTAAGCCTTTTAGGG
CTGCTAGCAATGGGGTGGGGGCCGTTACTAAAATGGCAGCAAGGCCTGTTTCAGCGCCGCAAACGCGTTTTGACGGAGTT
TGTGGTCTCCGCTGTACTCGGTGCCATGCTCTATTTGCTGCAAGTGCAGGTATGGGCGTCAATGACTTTGTTGTTCTGGT
GTGTTACGACCTGGGTGATTGTTAGCCACCTTCGGTTATTGTTTGTTATGCCACCAACAAAGAGGCGCCAAAAACTGCCA
ATGGTGCTTTCTCATATTGGTATTGCATTGGTGTGCCTCGGCGCGATGATGAATGCCCAACATTCGTTTGAACGAAATGT
TCGTGTGGAACCTAACTCGTACCATCAGTTCGATGGCTTTTCCATTCGTTATCAAGGAATTGACTGGTCCATTGGACCAA
ACTACACCGCTGAGCGAGCGTCGGTCTCACTCATCCTTGCCGATAGGCAATTTCAATTGTTGCCTGAAAGACGGCATTAC
CCGGTGAGGGTCATGAACATGACAGAGCCCGCAATCAAGTCTTTTTGGCATGGGGATTACTACCTGACTCTGGGTGAGAA
AGTCGGGCTTAAAGCCTATGCGTTGAAGATCCAATACCGTGCTTACATTTGGTGGATCTGGCTAGGCGGTTTGATGGTTG
TTGCTGCGGTGTTCACTGCATTACAGCCAGTTCAGCAACGCGTTAAGGTGGAGCGCTACTGTGAACAACAAAGTTACTAA

Upstream 100 bases:

>100_bases
ATTTTTGTGGTCACGACACTTAGCATGGTTGGCGTTTTGATGCTGCGTACGTTTATTTTGTACGCCGGCCAGATGACGGT
TGTCTAATTAAGGAGTATAG

Downstream 100 bases:

>100_bases
GTTGCTTGTGTTGGTGAGCATCGTCGGCATCGTTACGTTTACCGCAGTCTTGGGCATTGAACGACAAAATGCTGGTCACA
CAACGCCTGACACTCTGATT

Product: cytochrome c-type heme lyase subunit NrfE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MEAELGLICLILAAVGSSFAVILHAMNRLLSKQTPLALMLGCGYLVALSSAFSLLYLILAFVADDFALAYVASHSNSQLP
VIFKIAASWGGHQGSMLFWVVTLSLWACLIRSRDEFSSQYKADYIAVMLMLTAIFAWFTLLTSNPFEYAPSLASDGRDLN
PMLQDVGLILHPPLLYLGYVGFASILALGVAALLQPSAIHHWFQAGRDWAMVAWGFLTLGIIVGSWWAYNELGWGGWWFW
DPVENASLLPWLTATALLHTLVQSKRQGGVNKSSYMLAFLTFGFSVLGTFIVRSGILTSVHAFAVDPTKGIVLLLVMAFI
FLLTFALLILKSDSIPAKGITHWLSRQYLTLVAMGLLLIATSTVFLGTFYPMIYELLRLGSISVGAPYFNTMIAPLSLLG
LLAMGWGPLLKWQQGLFQRRKRVLTEFVVSAVLGAMLYLLQVQVWASMTLLFWCVTTWVIVSHLRLLFVMPPTKRRQKLP
MVLSHIGIALVCLGAMMNAQHSFERNVRVEPNSYHQFDGFSIRYQGIDWSIGPNYTAERASVSLILADRQFQLLPERRHY
PVRVMNMTEPAIKSFWHGDYYLTLGEKVGLKAYALKIQYRAYIWWIWLGGLMVVAAVFTALQPVQQRVKVERYCEQQSY

Sequences:

>Translated_639_residues
MEAELGLICLILAAVGSSFAVILHAMNRLLSKQTPLALMLGCGYLVALSSAFSLLYLILAFVADDFALAYVASHSNSQLP
VIFKIAASWGGHQGSMLFWVVTLSLWACLIRSRDEFSSQYKADYIAVMLMLTAIFAWFTLLTSNPFEYAPSLASDGRDLN
PMLQDVGLILHPPLLYLGYVGFASILALGVAALLQPSAIHHWFQAGRDWAMVAWGFLTLGIIVGSWWAYNELGWGGWWFW
DPVENASLLPWLTATALLHTLVQSKRQGGVNKSSYMLAFLTFGFSVLGTFIVRSGILTSVHAFAVDPTKGIVLLLVMAFI
FLLTFALLILKSDSIPAKGITHWLSRQYLTLVAMGLLLIATSTVFLGTFYPMIYELLRLGSISVGAPYFNTMIAPLSLLG
LLAMGWGPLLKWQQGLFQRRKRVLTEFVVSAVLGAMLYLLQVQVWASMTLLFWCVTTWVIVSHLRLLFVMPPTKRRQKLP
MVLSHIGIALVCLGAMMNAQHSFERNVRVEPNSYHQFDGFSIRYQGIDWSIGPNYTAERASVSLILADRQFQLLPERRHY
PVRVMNMTEPAIKSFWHGDYYLTLGEKVGLKAYALKIQYRAYIWWIWLGGLMVVAAVFTALQPVQQRVKVERYCEQQSY
>Mature_639_residues
MEAELGLICLILAAVGSSFAVILHAMNRLLSKQTPLALMLGCGYLVALSSAFSLLYLILAFVADDFALAYVASHSNSQLP
VIFKIAASWGGHQGSMLFWVVTLSLWACLIRSRDEFSSQYKADYIAVMLMLTAIFAWFTLLTSNPFEYAPSLASDGRDLN
PMLQDVGLILHPPLLYLGYVGFASILALGVAALLQPSAIHHWFQAGRDWAMVAWGFLTLGIIVGSWWAYNELGWGGWWFW
DPVENASLLPWLTATALLHTLVQSKRQGGVNKSSYMLAFLTFGFSVLGTFIVRSGILTSVHAFAVDPTKGIVLLLVMAFI
FLLTFALLILKSDSIPAKGITHWLSRQYLTLVAMGLLLIATSTVFLGTFYPMIYELLRLGSISVGAPYFNTMIAPLSLLG
LLAMGWGPLLKWQQGLFQRRKRVLTEFVVSAVLGAMLYLLQVQVWASMTLLFWCVTTWVIVSHLRLLFVMPPTKRRQKLP
MVLSHIGIALVCLGAMMNAQHSFERNVRVEPNSYHQFDGFSIRYQGIDWSIGPNYTAERASVSLILADRQFQLLPERRHY
PVRVMNMTEPAIKSFWHGDYYLTLGEKVGLKAYALKIQYRAYIWWIWLGGLMVVAAVFTALQPVQQRVKVERYCEQQSY

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=600, Percent_Identity=37.5, Blast_Score=367, Evalue=1e-102,
Organism=Escherichia coli, GI1790511, Length=569, Percent_Identity=36.3796133567663, Blast_Score=271, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568
- InterPro:   IPR003570
- InterPro:   IPR017563 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 71665; Mature: 71665

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAELGLICLILAAVGSSFAVILHAMNRLLSKQTPLALMLGCGYLVALSSAFSLLYLILA
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FVADDFALAYVASHSNSQLPVIFKIAASWGGHQGSMLFWVVTLSLWACLIRSRDEFSSQY
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHH
KADYIAVMLMLTAIFAWFTLLTSNPFEYAPSLASDGRDLNPMLQDVGLILHPPLLYLGYV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHCCCCCCCHHHHHCCHHHCCHHHHHHHH
GFASILALGVAALLQPSAIHHWFQAGRDWAMVAWGFLTLGIIVGSWWAYNELGWGGWWFW
HHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEE
DPVENASLLPWLTATALLHTLVQSKRQGGVNKSSYMLAFLTFGFSVLGTFIVRSGILTSV
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAFAVDPTKGIVLLLVMAFIFLLTFALLILKSDSIPAKGITHWLSRQYLTLVAMGLLLIA
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSTVFLGTFYPMIYELLRLGSISVGAPYFNTMIAPLSLLGLLAMGWGPLLKWQQGLFQRR
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KRVLTEFVVSAVLGAMLYLLQVQVWASMTLLFWCVTTWVIVSHLRLLFVMPPTKRRQKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHH
MVLSHIGIALVCLGAMMNAQHSFERNVRVEPNSYHQFDGFSIRYQGIDWSIGPNYTAERA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
SVSLILADRQFQLLPERRHYPVRVMNMTEPAIKSFWHGDYYLTLGEKVGLKAYALKIQYR
EEEEEEECCHHHHCCCCCCCCEEEECCCCHHHHHHHCCCEEEEECCCCCCEEEEEEEEHH
AYIWWIWLGGLMVVAAVFTALQPVQQRVKVERYCEQQSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEAELGLICLILAAVGSSFAVILHAMNRLLSKQTPLALMLGCGYLVALSSAFSLLYLILA
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FVADDFALAYVASHSNSQLPVIFKIAASWGGHQGSMLFWVVTLSLWACLIRSRDEFSSQY
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHH
KADYIAVMLMLTAIFAWFTLLTSNPFEYAPSLASDGRDLNPMLQDVGLILHPPLLYLGYV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHCCCCCCCHHHHHCCHHHCCHHHHHHHH
GFASILALGVAALLQPSAIHHWFQAGRDWAMVAWGFLTLGIIVGSWWAYNELGWGGWWFW
HHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEE
DPVENASLLPWLTATALLHTLVQSKRQGGVNKSSYMLAFLTFGFSVLGTFIVRSGILTSV
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAFAVDPTKGIVLLLVMAFIFLLTFALLILKSDSIPAKGITHWLSRQYLTLVAMGLLLIA
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSTVFLGTFYPMIYELLRLGSISVGAPYFNTMIAPLSLLGLLAMGWGPLLKWQQGLFQRR
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KRVLTEFVVSAVLGAMLYLLQVQVWASMTLLFWCVTTWVIVSHLRLLFVMPPTKRRQKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHH
MVLSHIGIALVCLGAMMNAQHSFERNVRVEPNSYHQFDGFSIRYQGIDWSIGPNYTAERA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
SVSLILADRQFQLLPERRHYPVRVMNMTEPAIKSFWHGDYYLTLGEKVGLKAYALKIQYR
EEEEEEECCHHHHCCCCCCCCEEEECCCCHHHHHHHCCCEEEEECCCCCCEEEEEEEEHH
AYIWWIWLGGLMVVAAVFTALQPVQQRVKVERYCEQQSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]