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The map label for this gene is 27366055

Identifier: 27366055

GI number: 27366055

Start: 2829908

End: 2831044

Strand: Reverse

Name: 27366055

Synonym: VV1_2767

Alternate gene names: NA

Gene position: 2831044-2829908 (Counterclockwise)

Preceding gene: 27366056

Following gene: 27366054

Centisome position: 86.26

GC content: 49.43

Gene sequence:

>1137_bases
ATGCATAAATGGATCACCTTTCCTCATCGGGAAGGTGTCTGCTCCAAGCAGGCACATGCCGATTTTCCTGAAGAGGCGAT
TTACGAACGTGAAGCGGGGCGTAGTGGGTTCTTTGGCCCCGCTGCGCATTTTCATCATCAACATGCCCCAACAGGCTGGA
CCGATTGGCAAGGCGATTTAAGACCGAGAGCGTTTGATTTCACTCGCGTGACCAGCGCCAATCAAGCTTCTCCTTGGAGT
GTGCCGCATTTGCTTCACAATCACGAATGTAAAGTTCGAGTCTGGAAAACCCAAACTAAAATGGAATTTCTGGCGCGAAA
CGCCGATGGCGACGAGCTGCTCTTTATCCATCAAGGTAAGGCCGACCTTTACTGTGACTATGGCCATTTGTCAGTAGAAG
AAGGGGATTACGTGATGATCCCGCGTTCAACCAACTGGCGCTTGGAGCCGTCAGAGGCGATGTTTATTTTGATGATTGAA
AACACCGATGCGGCGTATTCACTGCCAGAGAAAGGGTTAGTTGGTAATCATGCGGTATTTGACCCTGCGGTACTTGAAAC
GCCGTCGATTAACGACCAGTTCAAAGCGCAATACTCAGAGCAAGAGACGCGTGTGGAAGTGAAACGCCACGACAGTGTGA
GCGTGATTACTTACCCATTCAATCCATTGGATGCCATAGGTTGGCATGGTGATCTCTCCGTAGTGAAACTGAACTGGCGC
GATATACGCCCATTGATGTCTCATCGTTATCACTTGCCACCGTCGGCACACACCACCTTTGTTGGGAACGGCTTTGTTGT
TTGCACCTTCGTGCCGCGTCCTATCGAAAGTGACCCTGGCGCGTTGAAAGTGCCGTTTTATCACAACAACGACGATTATG
ATGAAGTGTTGTTCTATCATGCGGGGGATTTTTTCAGCCGCGACAACATTGAAGCAGGCATGGTGACGTTTCACCCGGCA
GGCTTTACCCACGGGCCGCATCCTAAGGCATTCAAAGCTGGCCAAGAGTATAAGAAAAAGTTCACCGACGAAGTCGCGGT
GATGATTGATACGCGCCATGCATTAACGTTTGCACAAGAGCTCGACAGTGTAGAAAACAAAGAATACGTCTACAGTTGGC
GTGAAAATCAAAAATAA

Upstream 100 bases:

>100_bases
ATCATTCAGCGTAAAGGCAATGAAGGTTTTGGCGAAGGTAACTTCAAAGCGCTATTCGAATCGATAGAAGAAGATCAAAT
TCGCCGTGGAGTACTCAATA

Downstream 100 bases:

>100_bases
TACGGACGACAGAACAGCAAGGTTTGAGAAGGGAAGAGAGATGAAATTAGCAACCAAGAAGAATGAGCATCGCGATGGTG
AGTTGATCGTCGTTAGTCGC

Product: Homogentisate 1,2-dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MHKWITFPHREGVCSKQAHADFPEEAIYEREAGRSGFFGPAAHFHHQHAPTGWTDWQGDLRPRAFDFTRVTSANQASPWS
VPHLLHNHECKVRVWKTQTKMEFLARNADGDELLFIHQGKADLYCDYGHLSVEEGDYVMIPRSTNWRLEPSEAMFILMIE
NTDAAYSLPEKGLVGNHAVFDPAVLETPSINDQFKAQYSEQETRVEVKRHDSVSVITYPFNPLDAIGWHGDLSVVKLNWR
DIRPLMSHRYHLPPSAHTTFVGNGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYHAGDFFSRDNIEAGMVTFHPA
GFTHGPHPKAFKAGQEYKKKFTDEVAVMIDTRHALTFAQELDSVENKEYVYSWRENQK

Sequences:

>Translated_378_residues
MHKWITFPHREGVCSKQAHADFPEEAIYEREAGRSGFFGPAAHFHHQHAPTGWTDWQGDLRPRAFDFTRVTSANQASPWS
VPHLLHNHECKVRVWKTQTKMEFLARNADGDELLFIHQGKADLYCDYGHLSVEEGDYVMIPRSTNWRLEPSEAMFILMIE
NTDAAYSLPEKGLVGNHAVFDPAVLETPSINDQFKAQYSEQETRVEVKRHDSVSVITYPFNPLDAIGWHGDLSVVKLNWR
DIRPLMSHRYHLPPSAHTTFVGNGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYHAGDFFSRDNIEAGMVTFHPA
GFTHGPHPKAFKAGQEYKKKFTDEVAVMIDTRHALTFAQELDSVENKEYVYSWRENQK
>Mature_378_residues
MHKWITFPHREGVCSKQAHADFPEEAIYEREAGRSGFFGPAAHFHHQHAPTGWTDWQGDLRPRAFDFTRVTSANQASPWS
VPHLLHNHECKVRVWKTQTKMEFLARNADGDELLFIHQGKADLYCDYGHLSVEEGDYVMIPRSTNWRLEPSEAMFILMIE
NTDAAYSLPEKGLVGNHAVFDPAVLETPSINDQFKAQYSEQETRVEVKRHDSVSVITYPFNPLDAIGWHGDLSVVKLNWR
DIRPLMSHRYHLPPSAHTTFVGNGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYHAGDFFSRDNIEAGMVTFHPA
GFTHGPHPKAFKAGQEYKKKFTDEVAVMIDTRHALTFAQELDSVENKEYVYSWRENQK

Specific function: Unknown

COG id: COG3508

COG function: function code Q; Homogentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homogentisate dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR005708
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04209 HgmA [H]

EC number: NA

Molecular weight: Translated: 43418; Mature: 43418

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKWITFPHREGVCSKQAHADFPEEAIYEREAGRSGFFGPAAHFHHQHAPTGWTDWQGDL
CCCCEECCCCCCCCCCHHCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
RPRAFDFTRVTSANQASPWSVPHLLHNHECKVRVWKTQTKMEFLARNADGDELLFIHQGK
CCCEEEEEEECCCCCCCCCCCCHHHCCCCEEEEEEECHHHHHHHHCCCCCCEEEEEECCC
ADLYCDYGHLSVEEGDYVMIPRSTNWRLEPSEAMFILMIENTDAAYSLPEKGLVGNHAVF
CCEEEECCEEEECCCCEEEEECCCCCEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
DPAVLETPSINDQFKAQYSEQETRVEVKRHDSVSVITYPFNPLDAIGWHGDLSVVKLNWR
CCHHCCCCCCCHHHHHHHCCCHHEEEEEECCCEEEEEECCCCHHHCCCCCCEEEEEECHH
DIRPLMSHRYHLPPSAHTTFVGNGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYH
HHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHEEEEE
AGDFFSRDNIEAGMVTFHPAGFTHGPHPKAFKAGQEYKKKFTDEVAVMIDTRHALTFAQE
CCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHCCHHHHHHHCCCEEEEEECHHHHHHHHH
LDSVENKEYVYSWRENQK
HHCCCCCEEEEEECCCCC
>Mature Secondary Structure
MHKWITFPHREGVCSKQAHADFPEEAIYEREAGRSGFFGPAAHFHHQHAPTGWTDWQGDL
CCCCEECCCCCCCCCCHHCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
RPRAFDFTRVTSANQASPWSVPHLLHNHECKVRVWKTQTKMEFLARNADGDELLFIHQGK
CCCEEEEEEECCCCCCCCCCCCHHHCCCCEEEEEEECHHHHHHHHCCCCCCEEEEEECCC
ADLYCDYGHLSVEEGDYVMIPRSTNWRLEPSEAMFILMIENTDAAYSLPEKGLVGNHAVF
CCEEEECCEEEECCCCEEEEECCCCCEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
DPAVLETPSINDQFKAQYSEQETRVEVKRHDSVSVITYPFNPLDAIGWHGDLSVVKLNWR
CCHHCCCCCCCHHHHHHHCCCHHEEEEEECCCEEEEEECCCCHHHCCCCCCEEEEEECHH
DIRPLMSHRYHLPPSAHTTFVGNGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYH
HHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHEEEEE
AGDFFSRDNIEAGMVTFHPAGFTHGPHPKAFKAGQEYKKKFTDEVAVMIDTRHALTFAQE
CCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHCCHHHHHHHCCCEEEEEECHHHHHHHHH
LDSVENKEYVYSWRENQK
HHCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]