Definition Vibrio vulnificus CMCP6 chromosome chromosome I, complete sequence.
Accession NC_004459
Length 3,281,866

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The map label for this gene is hutI

Identifier: 27365711

GI number: 27365711

Start: 2430756

End: 2431976

Strand: Reverse

Name: hutI

Synonym: VV1_2392

Alternate gene names: 27365711

Gene position: 2431976-2430756 (Counterclockwise)

Preceding gene: 27365712

Following gene: 27365710

Centisome position: 74.1

GC content: 50.04

Gene sequence:

>1221_bases
ATGGATCTGTTGCTTACCAACGCACGCCTTGTCACTTTGCAATCAGGGGAAATGGGTTATCAACCCAGCACGCCGATGTC
GATTGGCATTAAGGCGGGGAAGATCCATTATCTAGGCATTGACACGGCACTGGCTGCTACTAAGCAAATTGATCTAAAAG
GTAAGCTGGTTACTCCCGGCCTTATCGACTGCCACACACATCTTGTTTACGCGGGTAATCGGTCCAACGAATTTGAAATG
CGATTGCAGGGCGTTCCCTATCAAGAAATCGCTCGCCAAGGCGGGGGCATTCTTTCTACCGTTTACGCGACACGCCAAGC
CAGTGAAGCGCAGTTACTCGAACAAACGCTACCACGTCTTGATGGCTTGCTTGCCAGTGGCGTCACTTCGGTTGAAGTCA
AATCGGGTTATGGATTGACACTGGTTGATGAAATCAAAATGCTGCGAGTGGCAAAGTCCTTATCACAGCATCGATTGGTG
AAGGTCACACCAACACTGTTGGCCGCCCATGCCCTCCCCCCTGAATTTACTGGCCGTGCGAACGACTACATCGAGTTTAT
TTGCCAAGAGATCATCCCACTGGTGGCCGAAGAACAGTTAGCCACCAGCGTCGATGTATTTTGTGAGTCAATTGGGTTTG
ATTTGGCACAAACAGAAAGAGTCTATGCGTGTGCTGTCGAGCACGGGCTGCGTATCAAAGGGCACACAGAGCAACTGTCA
AATTTGGGCGGAACCGCTTTAACTGCTCGTTATCAGGGGCTTTCTGCTGACCATATTGAATTTCTTGATCCAGCAGGCGT
CGAAGCACTTGCCCGTTCATCGACCGTCGCGACTCTATTGCCTGGGGCGTTCTATTTTCTGCGTGAAACTCAATTGCCGC
CGATTGAACTATTGCGTCAGTTTGGTGTGCCCATGGCCATTGCCAGCGATGTTAACCCCGGCACCTCACCATTTTGTGAT
TTAACTTTAATGATGAACATGGCTTGTACCCTCTTTCGTTTAACGCCAGAAGAAGCTTTACGTGGCGTCACTCAAAATGC
GGCGCAAGCATTGGGCTATGCGGAGAGTCGAGGGCAAATCAAAACAGGTTATGAAGCGGATCTCGCCATCTGGCAGATCG
AGCATCCCGCCGATCTCAGTTATCAAGTCGGAACTCAGCGTCTCTTTGCAAGAGTCGTTGATGGTCAATTCGAGCAACAC
AAGGAGTGTTGTGATGAGTAA

Upstream 100 bases:

>100_bases
TTTGATCACATTTCAGCAACATTCACCTTGTCACAACGGTTATTTTCTCCTATTTATTTGTATATACATTTAGTCAATAC
AAATCATTGGAACCTTAATC

Downstream 100 bases:

>100_bases
ACATTTTTTTCTTCATAATGAATTTCATTGGCAAGGTCGCCACGATGCGGAAGACGGTGCCGCGGGTTCGCGTGTTCATC
ATGTGGTGCAGCAGATTGAT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MDLLLTNARLVTLQSGEMGYQPSTPMSIGIKAGKIHYLGIDTALAATKQIDLKGKLVTPGLIDCHTHLVYAGNRSNEFEM
RLQGVPYQEIARQGGGILSTVYATRQASEAQLLEQTLPRLDGLLASGVTSVEVKSGYGLTLVDEIKMLRVAKSLSQHRLV
KVTPTLLAAHALPPEFTGRANDYIEFICQEIIPLVAEEQLATSVDVFCESIGFDLAQTERVYACAVEHGLRIKGHTEQLS
NLGGTALTARYQGLSADHIEFLDPAGVEALARSSTVATLLPGAFYFLRETQLPPIELLRQFGVPMAIASDVNPGTSPFCD
LTLMMNMACTLFRLTPEEALRGVTQNAAQALGYAESRGQIKTGYEADLAIWQIEHPADLSYQVGTQRLFARVVDGQFEQH
KECCDE

Sequences:

>Translated_406_residues
MDLLLTNARLVTLQSGEMGYQPSTPMSIGIKAGKIHYLGIDTALAATKQIDLKGKLVTPGLIDCHTHLVYAGNRSNEFEM
RLQGVPYQEIARQGGGILSTVYATRQASEAQLLEQTLPRLDGLLASGVTSVEVKSGYGLTLVDEIKMLRVAKSLSQHRLV
KVTPTLLAAHALPPEFTGRANDYIEFICQEIIPLVAEEQLATSVDVFCESIGFDLAQTERVYACAVEHGLRIKGHTEQLS
NLGGTALTARYQGLSADHIEFLDPAGVEALARSSTVATLLPGAFYFLRETQLPPIELLRQFGVPMAIASDVNPGTSPFCD
LTLMMNMACTLFRLTPEEALRGVTQNAAQALGYAESRGQIKTGYEADLAIWQIEHPADLSYQVGTQRLFARVVDGQFEQH
KECCDE
>Mature_406_residues
MDLLLTNARLVTLQSGEMGYQPSTPMSIGIKAGKIHYLGIDTALAATKQIDLKGKLVTPGLIDCHTHLVYAGNRSNEFEM
RLQGVPYQEIARQGGGILSTVYATRQASEAQLLEQTLPRLDGLLASGVTSVEVKSGYGLTLVDEIKMLRVAKSLSQHRLV
KVTPTLLAAHALPPEFTGRANDYIEFICQEIIPLVAEEQLATSVDVFCESIGFDLAQTERVYACAVEHGLRIKGHTEQLS
NLGGTALTARYQGLSADHIEFLDPAGVEALARSSTVATLLPGAFYFLRETQLPPIELLRQFGVPMAIASDVNPGTSPFCD
LTLMMNMACTLFRLTPEEALRGVTQNAAQALGYAESRGQIKTGYEADLAIWQIEHPADLSYQVGTQRLFARVVDGQFEQH
KECCDE

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=340, Percent_Identity=37.0588235294118, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17555004, Length=359, Percent_Identity=32.8690807799443, Blast_Score=198, Evalue=5e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_VIBVU (Q8DA18)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_761239.1
- ProteinModelPortal:   Q8DA18
- SMR:   Q8DA18
- GeneID:   1179267
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_2392
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   VVUL216895:VV1_2392-MONOMER
- BRENDA:   3.5.2.7
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 44241; Mature: 44241

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00290 IG_MHC

Important sites: BINDING 74-74 BINDING 87-87 BINDING 137-137 BINDING 170-170 BINDING 238-238

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MDLLLTNARLVTLQSGEMGYQPSTPMSIGIKAGKIHYLGIDTALAATKQIDLKGKLVTPG
CCEEEECCEEEEEECCCCCCCCCCCCEEEEEECEEEEEECHHHHHHHHEECCCCEEECCC
LIDCHTHLVYAGNRSNEFEMRLQGVPYQEIARQGGGILSTVYATRQASEAQLLEQTLPRL
EEECCEEEEEECCCCCCEEEEECCCCHHHHHHCCCCEEEHHHHHHCHHHHHHHHHHHHHH
DGLLASGVTSVEVKSGYGLTLVDEIKMLRVAKSLSQHRLVKVTPTLLAAHALPPEFTGRA
HHHHHCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHCCEEEECHHHHHHHCCCCCCCCCH
NDYIEFICQEIIPLVAEEQLATSVDVFCESIGFDLAQTERVYACAVEHGLRIKGHTEQLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEHHHCCCEECCCHHHHH
NLGGTALTARYQGLSADHIEFLDPAGVEALARSSTVATLLPGAFYFLRETQLPPIELLRQ
HCCCCEEEEEECCCCCCCHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHH
FGVPMAIASDVNPGTSPFCDLTLMMNMACTLFRLTPEEALRGVTQNAAQALGYAESRGQI
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCHHCCCCC
KTGYEADLAIWQIEHPADLSYQVGTQRLFARVVDGQFEQHKECCDE
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MDLLLTNARLVTLQSGEMGYQPSTPMSIGIKAGKIHYLGIDTALAATKQIDLKGKLVTPG
CCEEEECCEEEEEECCCCCCCCCCCCEEEEEECEEEEEECHHHHHHHHEECCCCEEECCC
LIDCHTHLVYAGNRSNEFEMRLQGVPYQEIARQGGGILSTVYATRQASEAQLLEQTLPRL
EEECCEEEEEECCCCCCEEEEECCCCHHHHHHCCCCEEEHHHHHHCHHHHHHHHHHHHHH
DGLLASGVTSVEVKSGYGLTLVDEIKMLRVAKSLSQHRLVKVTPTLLAAHALPPEFTGRA
HHHHHCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHCCEEEECHHHHHHHCCCCCCCCCH
NDYIEFICQEIIPLVAEEQLATSVDVFCESIGFDLAQTERVYACAVEHGLRIKGHTEQLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEHHHCCCEECCCHHHHH
NLGGTALTARYQGLSADHIEFLDPAGVEALARSSTVATLLPGAFYFLRETQLPPIELLRQ
HCCCCEEEEEECCCCCCCHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHH
FGVPMAIASDVNPGTSPFCDLTLMMNMACTLFRLTPEEALRGVTQNAAQALGYAESRGQI
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCHHCCCCC
KTGYEADLAIWQIEHPADLSYQVGTQRLFARVVDGQFEQHKECCDE
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA