Click here to switch to the map view.

The map label for this gene is aaeR [H]

Identifier: 27365341

GI number: 27365341

Start: 1994918

End: 1995793

Strand: Reverse

Name: aaeR [H]

Synonym: VV1_1998

Alternate gene names: 27365341

Gene position: 1995793-1994918 (Counterclockwise)

Preceding gene: 27365348

Following gene: 27365330

Centisome position: 60.81

GC content: 46.58

Gene sequence:

>876_bases
ATGAAATTAGACGATCTCAACCTGTTCAGACTCGTTGTTGAAAATGGGAGCTACACCGCAACTTCACGTAAGACCATGAT
CCCCGTGGCGACCATCACCCGACGCATACAAGCTTTGGAAGATGCGGTGAACTTGCGCCTTCTCAATCGCCATGCACGTA
AATTATCACTGACAGAAGCGGGAGAACGCTTTTTCCGTGAATGCTCTCCTTTACTGCAAAGACTCACAAACACAGCCGAA
GAAATTACCGATGAATGTCGTGGTGCGTCTGGCAAAATCAAGATTTCAACGCCCTACAATCTCACCAAGCGCATGATGAT
GCCAATGTTGAACGGTTTTATGAGTCAGTATCCAGAAATCAACATTGAACTCACTACAGAGAGTAACGCTGATCAACTTG
ACCCAACCGAATGGGATGTCATTTTCCGCGTAGGACCACAAAGAGATTCAAGCCTTATCGCGCGTAAAATTGGTTCAGTG
AAAGATATTTTGGTGGCTAGCCCTGAGTACGTAAACGCTCACCCAATGCCAACTCATGCTGAAGATCTGCACGACCACTT
CCTACTCAAAGGCCACCCGCTGTTGAAGTGGACATTAATCAACAGCAAAGGCGAAACCGTTGTTAACGTTGATCGTGGTC
GCTTTCAAGCCAACGCACTGAATGTGGTACGTAGCGCGTGCTCAGAAGGGCTAGGCATCACTCTCATGCCAGACGTGATG
ATAAAAGAGTATATCGCCGATGGCAGCCTAGTGCGTATTCTGCCTGACTGGAGTGCAAACCCACGCGATATTTATATGCT
CTACAATCACAAAGATCACTTACCCGAAAAAGTGCGTTTGTTTATCGACTACGTGATTGCTTATAACATCCACTAA

Upstream 100 bases:

>100_bases
TGCTGATCACAAATCGTGCGACCTGTTGACATGAAGCAAACTTTCATCGCAAAGTTAGCGCTAAATTAGGCCTATTTGGT
AAATAGATGTGTCAGGAAAT

Downstream 100 bases:

>100_bases
CGATGTAGCGCGTAACCACAGAGGTTATTTCGAGCACAAAAAAACCAGAGCAGAAAAGCTCTGGTTTTTATTTGTCTTAT
CTTAACCCTGAACTCCGGTG

Product: putative transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKLDDLNLFRLVVENGSYTATSRKTMIPVATITRRIQALEDAVNLRLLNRHARKLSLTEAGERFFRECSPLLQRLTNTAE
EITDECRGASGKIKISTPYNLTKRMMMPMLNGFMSQYPEINIELTTESNADQLDPTEWDVIFRVGPQRDSSLIARKIGSV
KDILVASPEYVNAHPMPTHAEDLHDHFLLKGHPLLKWTLINSKGETVVNVDRGRFQANALNVVRSACSEGLGITLMPDVM
IKEYIADGSLVRILPDWSANPRDIYMLYNHKDHLPEKVRLFIDYVIAYNIH

Sequences:

>Translated_291_residues
MKLDDLNLFRLVVENGSYTATSRKTMIPVATITRRIQALEDAVNLRLLNRHARKLSLTEAGERFFRECSPLLQRLTNTAE
EITDECRGASGKIKISTPYNLTKRMMMPMLNGFMSQYPEINIELTTESNADQLDPTEWDVIFRVGPQRDSSLIARKIGSV
KDILVASPEYVNAHPMPTHAEDLHDHFLLKGHPLLKWTLINSKGETVVNVDRGRFQANALNVVRSACSEGLGITLMPDVM
IKEYIADGSLVRILPDWSANPRDIYMLYNHKDHLPEKVRLFIDYVIAYNIH
>Mature_291_residues
MKLDDLNLFRLVVENGSYTATSRKTMIPVATITRRIQALEDAVNLRLLNRHARKLSLTEAGERFFRECSPLLQRLTNTAE
EITDECRGASGKIKISTPYNLTKRMMMPMLNGFMSQYPEINIELTTESNADQLDPTEWDVIFRVGPQRDSSLIARKIGSV
KDILVASPEYVNAHPMPTHAEDLHDHFLLKGHPLLKWTLINSKGETVVNVDRGRFQANALNVVRSACSEGLGITLMPDVM
IKEYIADGSLVRILPDWSANPRDIYMLYNHKDHLPEKVRLFIDYVIAYNIH

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=28.7671232876712, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=28.6206896551724, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=29.2682926829268, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=26.1168384879725, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787589, Length=288, Percent_Identity=26.3888888888889, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=26.3888888888889, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=27.4914089347079, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789173, Length=286, Percent_Identity=24.1258741258741, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI157672245, Length=191, Percent_Identity=26.7015706806283, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790783, Length=254, Percent_Identity=26.3779527559055, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787601, Length=124, Percent_Identity=25, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33133; Mature: 33133

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDDLNLFRLVVENGSYTATSRKTMIPVATITRRIQALEDAVNLRLLNRHARKLSLTEA
CCCCCCEEEEEEEECCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GERFFRECSPLLQRLTNTAEEITDECRGASGKIKISTPYNLTKRMMMPMLNGFMSQYPEI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCE
NIELTTESNADQLDPTEWDVIFRVGPQRDSSLIARKIGSVKDILVASPEYVNAHPMPTHA
EEEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCHHHHEEECCCCCCCCCCCCCH
EDLHDHFLLKGHPLLKWTLINSKGETVVNVDRGRFQANALNVVRSACSEGLGITLMPDVM
HHHHHHHEECCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEECHHHH
IKEYIADGSLVRILPDWSANPRDIYMLYNHKDHLPEKVRLFIDYVIAYNIH
HHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MKLDDLNLFRLVVENGSYTATSRKTMIPVATITRRIQALEDAVNLRLLNRHARKLSLTEA
CCCCCCEEEEEEEECCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GERFFRECSPLLQRLTNTAEEITDECRGASGKIKISTPYNLTKRMMMPMLNGFMSQYPEI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCE
NIELTTESNADQLDPTEWDVIFRVGPQRDSSLIARKIGSVKDILVASPEYVNAHPMPTHA
EEEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCHHHHEEECCCCCCCCCCCCCH
EDLHDHFLLKGHPLLKWTLINSKGETVVNVDRGRFQANALNVVRSACSEGLGITLMPDVM
HHHHHHHEECCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEECHHHH
IKEYIADGSLVRILPDWSANPRDIYMLYNHKDHLPEKVRLFIDYVIAYNIH
HHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]