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The map label for this gene is coaA

Identifier: 27364606

GI number: 27364606

Start: 1180825

End: 1181748

Strand: Reverse

Name: coaA

Synonym: VV1_1200

Alternate gene names: 27364606

Gene position: 1181748-1180825 (Counterclockwise)

Preceding gene: 27364618

Following gene: 27364602

Centisome position: 36.01

GC content: 44.48

Gene sequence:

>924_bases
ATGAGCCCATTTTTGTCATTTAGTCGCGCGACTTGGTCTGAATTACGTAATTCAGTGCCAATGACGTTGTCTGAAGAAGA
CTTAAAAGCATTGCAAGGGATCAATGAAAATCTCACCATGCAAGAAGCCGTGGAAGTGTATCTCCCTCTTTCCCGATTAT
TGAATCTTTATGTGCAGGCAAGGCAGAGCCGCAATTCGGTGCTCCATCAGTTTTTGAATAATGATGAACACGCTCCTCCT
TTCGTCATCGGTATCGCAGGCAGTGTGGCTGTAGGTAAGAGCACCACCGCTCGGGTCTTATGTGCTCTACTCTCTCGCTG
GGAAAATCATCCAAAAGTCGAACTGGTCACCACTGATGGTTTTCTCTATCCAAAGAAAGAGCTGGATCAACGCGGTATCA
TGCATAAGAAAGGCTTTCCAGAATCTTATGATATGAAGAAGCTGGTGCAATTTGTCTCTGATGTCAAAGCAGGTAAACCG
GAGCTTGAGGTTCCTGTTTACTCGCATATTACTTACGACATTACGGAGGAAGTAAAGAAAGTAGATCGCCCCGATGTTTT
GATCATCGAAGGATTGAATGTGCTGCAAAGTGGCATGGACTATCCACACGATCCTCATCGTGTTTTTGTTTCTGATTTCC
TCGATTTCTCAATTTACGTTGATGCTGAAAGCAATACGATAGAACAATGGTATGTGGAGCGCTTTCTCAAGTTCCGTAAA
GGCGCGTTTACTCAACCTGGCTCGTACTTTAGTCACTATACTCAACTTAGCGAGCAGCAAGCCATCGAGAAAGCGCAACA
GATTTGGCGAGACATTAACGGCATTAATTTAACGGAAAACATTTTGCCAACCAAAGAGCGAGCTCAGCTGATTCTGCGCA
AGGGCCCAAATCACTTGGTTGAAGAGATTCTGCTACGTAAATAG

Upstream 100 bases:

>100_bases
CTCTTTTTTCAATGAGGATTCACTATTGTCATTTGCTTTCTGTTACTCATGATGTATTTTGCATTCTCTTTCACGATTCA
CATGGAAAGGAAGCGTTCAT

Downstream 100 bases:

>100_bases
AGACACTGACTCAGAATACCATTCGATTTCGTTACTGATCGTTAGCTCGCAAAGAGATTTCACCACCCACAAATGTTTGA
ATCCCTTCCACGGTTTTTAG

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSPFLSFSRATWSELRNSVPMTLSEEDLKALQGINENLTMQEAVEVYLPLSRLLNLYVQARQSRNSVLHQFLNNDEHAPP
FVIGIAGSVAVGKSTTARVLCALLSRWENHPKVELVTTDGFLYPKKELDQRGIMHKKGFPESYDMKKLVQFVSDVKAGKP
ELEVPVYSHITYDITEEVKKVDRPDVLIIEGLNVLQSGMDYPHDPHRVFVSDFLDFSIYVDAESNTIEQWYVERFLKFRK
GAFTQPGSYFSHYTQLSEQQAIEKAQQIWRDINGINLTENILPTKERAQLILRKGPNHLVEEILLRK

Sequences:

>Translated_307_residues
MSPFLSFSRATWSELRNSVPMTLSEEDLKALQGINENLTMQEAVEVYLPLSRLLNLYVQARQSRNSVLHQFLNNDEHAPP
FVIGIAGSVAVGKSTTARVLCALLSRWENHPKVELVTTDGFLYPKKELDQRGIMHKKGFPESYDMKKLVQFVSDVKAGKP
ELEVPVYSHITYDITEEVKKVDRPDVLIIEGLNVLQSGMDYPHDPHRVFVSDFLDFSIYVDAESNTIEQWYVERFLKFRK
GAFTQPGSYFSHYTQLSEQQAIEKAQQIWRDINGINLTENILPTKERAQLILRKGPNHLVEEILLRK
>Mature_306_residues
SPFLSFSRATWSELRNSVPMTLSEEDLKALQGINENLTMQEAVEVYLPLSRLLNLYVQARQSRNSVLHQFLNNDEHAPPF
VIGIAGSVAVGKSTTARVLCALLSRWENHPKVELVTTDGFLYPKKELDQRGIMHKKGFPESYDMKKLVQFVSDVKAGKPE
LEVPVYSHITYDITEEVKKVDRPDVLIIEGLNVLQSGMDYPHDPHRVFVSDFLDFSIYVDAESNTIEQWYVERFLKFRKG
AFTQPGSYFSHYTQLSEQQAIEKAQQIWRDINGINLTENILPTKERAQLILRKGPNHLVEEILLRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=308, Percent_Identity=61.3636363636364, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_VIBVU (Q8DD30)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_760134.1
- ProteinModelPortal:   Q8DD30
- SMR:   Q8DD30
- GeneID:   1178120
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_1200
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- ProtClustDB:   PRK05439
- BioCyc:   VVUL216895:VV1_1200-MONOMER
- BRENDA:   2.7.1.33
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 35279; Mature: 35148

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPFLSFSRATWSELRNSVPMTLSEEDLKALQGINENLTMQEAVEVYLPLSRLLNLYVQA
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RQSRNSVLHQFLNNDEHAPPFVIGIAGSVAVGKSTTARVLCALLSRWENHPKVELVTTDG
HHHHHHHHHHHHCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHHHCCCCCEEEEECCC
FLYPKKELDQRGIMHKKGFPESYDMKKLVQFVSDVKAGKPELEVPVYSHITYDITEEVKK
CCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHH
VDRPDVLIIEGLNVLQSGMDYPHDPHRVFVSDFLDFSIYVDAESNTIEQWYVERFLKFRK
CCCCCEEEECCHHHHHHCCCCCCCCHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHC
GAFTQPGSYFSHYTQLSEQQAIEKAQQIWRDINGINLTENILPTKERAQLILRKGPNHLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHCCCHHHH
EEILLRK
HHHHHCC
>Mature Secondary Structure 
SPFLSFSRATWSELRNSVPMTLSEEDLKALQGINENLTMQEAVEVYLPLSRLLNLYVQA
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RQSRNSVLHQFLNNDEHAPPFVIGIAGSVAVGKSTTARVLCALLSRWENHPKVELVTTDG
HHHHHHHHHHHHCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHHHCCCCCEEEEECCC
FLYPKKELDQRGIMHKKGFPESYDMKKLVQFVSDVKAGKPELEVPVYSHITYDITEEVKK
CCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHHHHHHH
VDRPDVLIIEGLNVLQSGMDYPHDPHRVFVSDFLDFSIYVDAESNTIEQWYVERFLKFRK
CCCCCEEEECCHHHHHHCCCCCCCCHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHC
GAFTQPGSYFSHYTQLSEQQAIEKAQQIWRDINGINLTENILPTKERAQLILRKGPNHLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHCCCHHHH
EEILLRK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA