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The map label for this gene is mpg1 [H]

Identifier: 27364253

GI number: 27364253

Start: 812582

End: 813628

Strand: Reverse

Name: mpg1 [H]

Synonym: VV1_0804

Alternate gene names: 27364253

Gene position: 813628-812582 (Counterclockwise)

Preceding gene: 326423770

Following gene: 27364252

Centisome position: 24.79

GC content: 43.36

Gene sequence:

>1047_bases
ATGAGCCACAACTGGAAAAAGATTTTAGTCTCACCCTCCGCTTCGATTCGTTCTGTGTTGAGGACTATTGATCAACAAGC
GTTGAAACTAGCCCTAGTCGTAGATGAGCAGAACAAGTTGTTAGGAACGGTCAGCGATGGTGATATTCGTCGTGCCATCT
TAAGAGATGCCTCATTGGAAGACAGTGTTGATTTGGTGATGAATACCCAGCCAACCACTGCCGATGTCAGCATGTCGAGA
GACAATATTCTCTCTTTGATGGAACGCAAAGAGCTGCATGCCATTCCAATCTTAAGTAATGGGATCGTGATTGGCTTGGA
AACATTGCATGGCTTGTTACATAAACCCGAATACGCCAATCCGGTCTTTTTAATGGCAGGAGGCTTTGGGACTCGCCTTA
AACCATTGACGGATAACTGCCCTAAACCATTACTCAAAGTGGGTGAGCGCCCGATCTTAGAAACGGTCATCTTGAGTTTT
ATTCGATCAGGATTTAGTAATTTCTATATCTCAACCCATTATTTACCAGAAATGATCCATGAAGCTTTGGGCGATGGTTC
GCGTTGGGGCGTGTCGATTCAATATATTCATGAAGAAACTCCATTAGGCACTGGCGGTGCGTTAGGCTTGCTACCAGATA
GTCTGCCAGATCTGCCCGTTATCGTGATGAATGGAGACATCCTGACCAAGATCAACTTTGAAGATGTGCTTGAGTTCCAT
AATAAAAATGACTCAAAAGCGACCATGTGTGTCCGTGAGTTTGAATATCAAGTGCCTTTTGGTGTAATTGAAGCTCAAGA
TTTCAAAATTACTGGGATTGTGGAAAAACCGACCTACCGCTTTCATGTCAACGCGGGCATTTATGTGTTGAACAAATCGC
TGATTACTTCGGTGGCGAAAGGAGAATACTTAGATATGCCAACCTTGTTTGAACAGCAAATTGGCCGAGACATCCATGTA
TTTCCATTTCATGAATATTGGCTAGATATTGGTCGCATGGACGACTATAAGCGTGCACAAGTGGATATTCTCACGTTAGG
TTTATAA

Upstream 100 bases:

>100_bases
GTTTTCGGGCTACCGATGAATGCGAATATCGCCAATTAGCACAAAGCCCAACACCAGTAAAATTTATTAAATACAGTCTC
TAAGCAAATAAGGCATACGC

Downstream 100 bases:

>100_bases
ATAATGAAAATACTGGCGATTACTCCTGCCCGCGGGGGCAGCAAGCGGCTACCAGGCAAGAACATCAAAAATTTAAATGG
TAAGCCTCTAATCCAATGGA

Product: D-glycero-D-manno-heptose 1-phosphate guanosyltransferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSHNWKKILVSPSASIRSVLRTIDQQALKLALVVDEQNKLLGTVSDGDIRRAILRDASLEDSVDLVMNTQPTTADVSMSR
DNILSLMERKELHAIPILSNGIVIGLETLHGLLHKPEYANPVFLMAGGFGTRLKPLTDNCPKPLLKVGERPILETVILSF
IRSGFSNFYISTHYLPEMIHEALGDGSRWGVSIQYIHEETPLGTGGALGLLPDSLPDLPVIVMNGDILTKINFEDVLEFH
NKNDSKATMCVREFEYQVPFGVIEAQDFKITGIVEKPTYRFHVNAGIYVLNKSLITSVAKGEYLDMPTLFEQQIGRDIHV
FPFHEYWLDIGRMDDYKRAQVDILTLGL

Sequences:

>Translated_348_residues
MSHNWKKILVSPSASIRSVLRTIDQQALKLALVVDEQNKLLGTVSDGDIRRAILRDASLEDSVDLVMNTQPTTADVSMSR
DNILSLMERKELHAIPILSNGIVIGLETLHGLLHKPEYANPVFLMAGGFGTRLKPLTDNCPKPLLKVGERPILETVILSF
IRSGFSNFYISTHYLPEMIHEALGDGSRWGVSIQYIHEETPLGTGGALGLLPDSLPDLPVIVMNGDILTKINFEDVLEFH
NKNDSKATMCVREFEYQVPFGVIEAQDFKITGIVEKPTYRFHVNAGIYVLNKSLITSVAKGEYLDMPTLFEQQIGRDIHV
FPFHEYWLDIGRMDDYKRAQVDILTLGL
>Mature_347_residues
SHNWKKILVSPSASIRSVLRTIDQQALKLALVVDEQNKLLGTVSDGDIRRAILRDASLEDSVDLVMNTQPTTADVSMSRD
NILSLMERKELHAIPILSNGIVIGLETLHGLLHKPEYANPVFLMAGGFGTRLKPLTDNCPKPLLKVGERPILETVILSFI
RSGFSNFYISTHYLPEMIHEALGDGSRWGVSIQYIHEETPLGTGGALGLLPDSLPDLPVIVMNGDILTKINFEDVLEFHN
KNDSKATMCVREFEYQVPFGVIEAQDFKITGIVEKPTYRFHVNAGIYVLNKSLITSVAKGEYLDMPTLFEQQIGRDIHVF
PFHEYWLDIGRMDDYKRAQVDILTLGL

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=227, Percent_Identity=28.1938325991189, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI11761619, Length=227, Percent_Identity=28.1938325991189, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI133931050, Length=224, Percent_Identity=27.2321428571429, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320148, Length=234, Percent_Identity=31.1965811965812, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355443, Length=227, Percent_Identity=29.0748898678414, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24644084, Length=227, Percent_Identity=29.0748898678414, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 38986; Mature: 38854

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNWKKILVSPSASIRSVLRTIDQQALKLALVVDEQNKLLGTVSDGDIRRAILRDASLE
CCCCCEEEEECCCHHHHHHHHHHHHHHEEEEEEEECCCCEEEECCCCHHHHHHHHCCCCC
DSVDLVMNTQPTTADVSMSRDNILSLMERKELHAIPILSNGIVIGLETLHGLLHKPEYAN
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHEECEEECCCEEEEHHHHHHHHCCCCCCC
PVFLMAGGFGTRLKPLTDNCPKPLLKVGERPILETVILSFIRSGFSNFYISTHYLPEMIH
EEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCHHHEEEEEHHHHHHHH
EALGDGSRWGVSIQYIHEETPLGTGGALGLLPDSLPDLPVIVMNGDILTKINFEDVLEFH
HHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECHHHHHHHH
NKNDSKATMCVREFEYQVPFGVIEAQDFKITGIVEKPTYRFHVNAGIYVLNKSLITSVAK
CCCCCHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCEEEEEECCCEEEECHHHHHHHHC
GEYLDMPTLFEQQIGRDIHVFPFHEYWLDIGRMDDYKRAQVDILTLGL
CCCCCCCHHHHHHHCCEEEEEECHHHHHHHCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
SHNWKKILVSPSASIRSVLRTIDQQALKLALVVDEQNKLLGTVSDGDIRRAILRDASLE
CCCCEEEEECCCHHHHHHHHHHHHHHEEEEEEEECCCCEEEECCCCHHHHHHHHCCCCC
DSVDLVMNTQPTTADVSMSRDNILSLMERKELHAIPILSNGIVIGLETLHGLLHKPEYAN
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHEECEEECCCEEEEHHHHHHHHCCCCCCC
PVFLMAGGFGTRLKPLTDNCPKPLLKVGERPILETVILSFIRSGFSNFYISTHYLPEMIH
EEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCHHHEEEEEHHHHHHHH
EALGDGSRWGVSIQYIHEETPLGTGGALGLLPDSLPDLPVIVMNGDILTKINFEDVLEFH
HHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECHHHHHHHH
NKNDSKATMCVREFEYQVPFGVIEAQDFKITGIVEKPTYRFHVNAGIYVLNKSLITSVAK
CCCCCHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCEEEEEECCCEEEECHHHHHHHHC
GEYLDMPTLFEQQIGRDIHVFPFHEYWLDIGRMDDYKRAQVDILTLGL
CCCCCCCHHHHHHHCCEEEEEECHHHHHHHCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]