Click here to switch to the map view.

The map label for this gene is cgtA [H]

Identifier: 27364126

GI number: 27364126

Start: 691336

End: 692505

Strand: Reverse

Name: cgtA [H]

Synonym: VV1_0669

Alternate gene names: 27364126

Gene position: 692505-691336 (Counterclockwise)

Preceding gene: 27364127

Following gene: 326423748

Centisome position: 21.1

GC content: 46.32

Gene sequence:

>1170_bases
ATGAAATTCGTTGATGAAGCGGTAATTAAAGTTCAAGCTGGCGACGGCGGAAACGGTGTTGTAAGTTTCTGGCGTGAAAA
ATTCGTGACCAAAGGTGGCCCAGATGGTGGCGACGGTGGTGACGGTGGTGATGTATACATCCAAGCTGACGAAAACTTAA
ATACGCTGATTGACTACCGTTTTCAACGCTTCTATGAAGCGGAGCGTGGCCAAAACGGTAGTGGTGGTAACTGTACCGGT
AAACGTGGTAAAGACATTACTTTACGCGTGCCAGTTGGTACACGTGCAGTCGATATTCATACCAATGAAATTGTGGCGGA
AGTCGCTGAGCACGGAAAGAAAGTCATGGTCGCCAAAGGCGGCTGGCATGGTTTAGGTAACACGCGTTTTAAATCGTCAG
TGAACCGCGCGCCACGTCAGAAAACCATGGGTACAAAAGGTGAGATTCGCGAACTGCGTTTGGAGCTATTGCTATTGGCT
GATGTGGGTATGTTAGGTTTGCCGAATGCTGGTAAATCAACCTTTATCCGCGCTGTCTTTGCAGCGAAACCGAAAGTCGC
GGATTACCCGTTTACTACCTTGATCCCAAGTCTCGGTGTTGTGAGTGTTGTTCCTGAGAAAAGCTTTGTTGTTGCTGATA
TTCCAGGGTTGATTGAAGGTGCAGCTGATGGCGCTGGTTTGGGGATTCGTTTCCTTAAACACTTAGAACGTTGTCGTGTA
CTGCTGCATATGATCGATATTTTCCCAATTGATCAATCGGATCCTGTACAAAATGCGCTGACCATCATTGATGAGTTAGA
GCAATACAGCGAGAAATTGGCCAATAAACCTCGTTGGTTAGTATTTAACAAGGTGGATCTTGTTAGTGAAGAGCAAGCGG
ATGAGATCATTCAAGAAGTGATTGATGCGCTAGGCTGGGAAGAGCAATACTTCAAGATCTCAGCGGTGAATCGCCAGGGT
ACTAAAGAGCTTTGTTACAAACTCGCTGACTTTATGGAACAGTTGCCACGTGAAGAGCAAGAAGTCTCTGAAGAAGAGAA
AGTGAACTTCATGTGGGATTACCACCCAGATGCAAATCAAGGCGAAGTTATCACTGAAGATGATGACGACGACTGGGATG
ACTGGGACGATGAAGAAGATGACGGTCACGTTATCTACGTTCGTGAGTAA

Upstream 100 bases:

>100_bases
CAGTCGACATATTCAAAACACCCTCTCATGGTGTCTTCGATCTGTCATCTGCTAAAATGTAGTGATATTGATTTACGGGC
GAAAGTAGCCGGAGTAAGAA

Downstream 100 bases:

>100_bases
TCGAGATATTACAATTAAAAGCCGCAATATTATTTGCGGCTTTTTTGCATCTAAATCATGTTTAGTCCGATTTTTTTCGG
GCAGAATATTTGTTTTTCGA

Product: GTPase CgtA

Products: NA

Alternate protein names: CgtA; GTP-binding protein Obg [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKFVDEAVIKVQAGDGGNGVVSFWREKFVTKGGPDGGDGGDGGDVYIQADENLNTLIDYRFQRFYEAERGQNGSGGNCTG
KRGKDITLRVPVGTRAVDIHTNEIVAEVAEHGKKVMVAKGGWHGLGNTRFKSSVNRAPRQKTMGTKGEIRELRLELLLLA
DVGMLGLPNAGKSTFIRAVFAAKPKVADYPFTTLIPSLGVVSVVPEKSFVVADIPGLIEGAADGAGLGIRFLKHLERCRV
LLHMIDIFPIDQSDPVQNALTIIDELEQYSEKLANKPRWLVFNKVDLVSEEQADEIIQEVIDALGWEEQYFKISAVNRQG
TKELCYKLADFMEQLPREEQEVSEEEKVNFMWDYHPDANQGEVITEDDDDDWDDWDDEEDDGHVIYVRE

Sequences:

>Translated_389_residues
MKFVDEAVIKVQAGDGGNGVVSFWREKFVTKGGPDGGDGGDGGDVYIQADENLNTLIDYRFQRFYEAERGQNGSGGNCTG
KRGKDITLRVPVGTRAVDIHTNEIVAEVAEHGKKVMVAKGGWHGLGNTRFKSSVNRAPRQKTMGTKGEIRELRLELLLLA
DVGMLGLPNAGKSTFIRAVFAAKPKVADYPFTTLIPSLGVVSVVPEKSFVVADIPGLIEGAADGAGLGIRFLKHLERCRV
LLHMIDIFPIDQSDPVQNALTIIDELEQYSEKLANKPRWLVFNKVDLVSEEQADEIIQEVIDALGWEEQYFKISAVNRQG
TKELCYKLADFMEQLPREEQEVSEEEKVNFMWDYHPDANQGEVITEDDDDDWDDWDDEEDDGHVIYVRE
>Mature_389_residues
MKFVDEAVIKVQAGDGGNGVVSFWREKFVTKGGPDGGDGGDGGDVYIQADENLNTLIDYRFQRFYEAERGQNGSGGNCTG
KRGKDITLRVPVGTRAVDIHTNEIVAEVAEHGKKVMVAKGGWHGLGNTRFKSSVNRAPRQKTMGTKGEIRELRLELLLLA
DVGMLGLPNAGKSTFIRAVFAAKPKVADYPFTTLIPSLGVVSVVPEKSFVVADIPGLIEGAADGAGLGIRFLKHLERCRV
LLHMIDIFPIDQSDPVQNALTIIDELEQYSEKLANKPRWLVFNKVDLVSEEQADEIIQEVIDALGWEEQYFKISAVNRQG
TKELCYKLADFMEQLPREEQEVSEEEKVNFMWDYHPDANQGEVITEDDDDDWDDWDDEEDDGHVIYVRE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=328, Percent_Identity=39.9390243902439, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI111955139, Length=352, Percent_Identity=32.3863636363636, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI111955063, Length=208, Percent_Identity=35.0961538461538, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI58761500, Length=131, Percent_Identity=32.0610687022901, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=33.8582677165354, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789574, Length=357, Percent_Identity=69.187675070028, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1787454, Length=129, Percent_Identity=31.7829457364341, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=328, Percent_Identity=36.890243902439, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17552324, Length=312, Percent_Identity=30.7692307692308, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17509631, Length=131, Percent_Identity=33.587786259542, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=166, Percent_Identity=37.9518072289157, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=30.952380952381, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24585318, Length=356, Percent_Identity=34.2696629213483, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI20129375, Length=285, Percent_Identity=38.9473684210526, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 43377; Mature: 43377

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEAVIKVQAGDGGNGVVSFWREKFVTKGGPDGGDGGDGGDVYIQADENLNTLIDYR
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHH
FQRFYEAERGQNGSGGNCTGKRGKDITLRVPVGTRAVDIHTNEIVAEVAEHGKKVMVAKG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHCCCEEEEECC
GWHGLGNTRFKSSVNRAPRQKTMGTKGEIRELRLELLLLADVGMLGLPNAGKSTFIRAVF
CCCCCCCHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTLIPSLGVVSVVPEKSFVVADIPGLIEGAADGAGLGIRFLKHLERCRV
HCCCCCCCCCHHHHHCCCCEEEECCCCCEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHH
LLHMIDIFPIDQSDPVQNALTIIDELEQYSEKLANKPRWLVFNKVDLVSEEQADEIIQEV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHCHHHHHHHHHHH
IDALGWEEQYFKISAVNRQGTKELCYKLADFMEQLPREEQEVSEEEKVNFMWDYHPDANQ
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHCEEEEEEECCCCCC
GEVITEDDDDDWDDWDDEEDDGHVIYVRE
CCEEECCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKFVDEAVIKVQAGDGGNGVVSFWREKFVTKGGPDGGDGGDGGDVYIQADENLNTLIDYR
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHH
FQRFYEAERGQNGSGGNCTGKRGKDITLRVPVGTRAVDIHTNEIVAEVAEHGKKVMVAKG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHCCCEEEEECC
GWHGLGNTRFKSSVNRAPRQKTMGTKGEIRELRLELLLLADVGMLGLPNAGKSTFIRAVF
CCCCCCCHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
AAKPKVADYPFTTLIPSLGVVSVVPEKSFVVADIPGLIEGAADGAGLGIRFLKHLERCRV
HCCCCCCCCCHHHHHCCCCEEEECCCCCEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHH
LLHMIDIFPIDQSDPVQNALTIIDELEQYSEKLANKPRWLVFNKVDLVSEEQADEIIQEV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHCHHHHHHHHHHH
IDALGWEEQYFKISAVNRQGTKELCYKLADFMEQLPREEQEVSEEEKVNFMWDYHPDANQ
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHCEEEEEEECCCCCC
GEVITEDDDDDWDDWDDEEDDGHVIYVRE
CCEEECCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11160812 [H]