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The map label for this gene is zraR [H]

Identifier: 27363988

GI number: 27363988

Start: 524179

End: 525513

Strand: Reverse

Name: zraR [H]

Synonym: VV1_0525

Alternate gene names: 27363988

Gene position: 525513-524179 (Counterclockwise)

Preceding gene: 27363989

Following gene: 27363987

Centisome position: 16.01

GC content: 46.67

Gene sequence:

>1335_bases
ATGGCTACTCAGTTTAAGATGGATTCTGTACCGGGGTCATTGGTAGTGGTTGGTGGTACTTATGAGCCTTGGTTGTCCGT
TTTGGAGCAGGTGGGCTGGAAGTGCCATCAATGTGCGGATTTACGCAAAGTGGACGCGCTGTTAGAAGATATTGGGCCAT
GCATCGGCATTGTTGACCTTAGCCATGATGAGTTCAGTCTCAATGGCATCGCTAATCTTGTGAGTACACACAAGCACGTG
CGCTGGCTCGCCTTTATTCGTGAACAGCAACTCAGCTCTGACACGATTTGCCAGTTTATCGTTAACTTTTGTATCGACTT
TTTCACCGCACCTATCCCTGATGCGCAACTGCTCAGTACGATAGGCCATCAATTGGGCATGTTAAAGCTCGAGAAGAAGG
TTTGGCCGACGTTTGGCAATAATCAAGATATGGGACTGATTGGGGAATCGGTTCCTTTGAAGCGCCTACGCGATCAAATT
AAACGCATTGGTCCTACCGATGTGAGCATTCTGATCAATGGGGAAAATGGCTCAGGAAAAGAAACGGTCGCTCGAGCCAT
TCATAAAATCTCATCGCGTGCGATGAAGCCATTCTTTTCTGTCAAATGTCGTGCAATGAGCGAGCAACGTTTTCAAGCGG
ATGTTTTTGGCATTGGGGCTGACGCAAATGCAGGGCCGTCAATACTAGAGCAGGCTGATGGTGGCACGGTGCTGTTTAAT
GACATTCTAACCATTTCCAAAACTCAGCAACTGCACCTTCTTCGTTTCTTGCAAGAAGGAACGATAGAAACCAGCGATGG
TATGAAGAAGGTCAATGTCCGCATTTTGACGGCGAATGCTTCCGATATTGAAAAAGCATTGATCGATGGGGATTTTAGTG
AAGAGCTTTACCACTACATCAATGTGCTGCGGATTAATGTGCCAAGTCTCAAAGAGCGTGCCAGTGACATCACCTTGTTG
GCTCGTTACTACCTGCAAGAGTACTCAAAAGAGTATAACGCGCAGGCAAAAGGCTATTCTGAAGAAGCGCTGAGAGCTTT
GATGCGTTATTACTGGCCTGGCAATGTACGCGAGCTGATGAATCAAATTAAGCGTGCTGTCTTGATGTCAGATAGCGTGA
TCATCGATGTGCCGCAATTGGATCTTCCTAAACGTGGCGATAGTAAACGCAGCTTAAAAAATATCCGTGAGAAAAGTGAG
CGCGATGCGCTATTGCTGGTACTGGAATCTCATTCTGGTCAGGTCTCTAATGCCGCCAAAGAATTGGGGGTTTCACGTGC
GACGATGTATCGACTGCTAAACAAACACAATTTGATTTCCGAACAAACGGTGTAG

Upstream 100 bases:

>100_bases
TTGAGTCTAGAATTAATTAACTGTCTCATATTTGAAACAGACTTATGAATCATTAGTCTCGATAATGTAACTAACGATCG
AAATAGTGAAAGGGTTGTAT

Downstream 100 bases:

>100_bases
CGGAATATCCTGTTTAAATCACCCAAAGCTTGAGGCCATTCTATTGAATGGCCTTTTTACATTCAGATAATCATCTAACA
ACCTCATATTGCTAAGGTGA

Product: transcriptional regulator VpsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MATQFKMDSVPGSLVVVGGTYEPWLSVLEQVGWKCHQCADLRKVDALLEDIGPCIGIVDLSHDEFSLNGIANLVSTHKHV
RWLAFIREQQLSSDTICQFIVNFCIDFFTAPIPDAQLLSTIGHQLGMLKLEKKVWPTFGNNQDMGLIGESVPLKRLRDQI
KRIGPTDVSILINGENGSGKETVARAIHKISSRAMKPFFSVKCRAMSEQRFQADVFGIGADANAGPSILEQADGGTVLFN
DILTISKTQQLHLLRFLQEGTIETSDGMKKVNVRILTANASDIEKALIDGDFSEELYHYINVLRINVPSLKERASDITLL
ARYYLQEYSKEYNAQAKGYSEEALRALMRYYWPGNVRELMNQIKRAVLMSDSVIIDVPQLDLPKRGDSKRSLKNIREKSE
RDALLLVLESHSGQVSNAAKELGVSRATMYRLLNKHNLISEQTV

Sequences:

>Translated_444_residues
MATQFKMDSVPGSLVVVGGTYEPWLSVLEQVGWKCHQCADLRKVDALLEDIGPCIGIVDLSHDEFSLNGIANLVSTHKHV
RWLAFIREQQLSSDTICQFIVNFCIDFFTAPIPDAQLLSTIGHQLGMLKLEKKVWPTFGNNQDMGLIGESVPLKRLRDQI
KRIGPTDVSILINGENGSGKETVARAIHKISSRAMKPFFSVKCRAMSEQRFQADVFGIGADANAGPSILEQADGGTVLFN
DILTISKTQQLHLLRFLQEGTIETSDGMKKVNVRILTANASDIEKALIDGDFSEELYHYINVLRINVPSLKERASDITLL
ARYYLQEYSKEYNAQAKGYSEEALRALMRYYWPGNVRELMNQIKRAVLMSDSVIIDVPQLDLPKRGDSKRSLKNIREKSE
RDALLLVLESHSGQVSNAAKELGVSRATMYRLLNKHNLISEQTV
>Mature_443_residues
ATQFKMDSVPGSLVVVGGTYEPWLSVLEQVGWKCHQCADLRKVDALLEDIGPCIGIVDLSHDEFSLNGIANLVSTHKHVR
WLAFIREQQLSSDTICQFIVNFCIDFFTAPIPDAQLLSTIGHQLGMLKLEKKVWPTFGNNQDMGLIGESVPLKRLRDQIK
RIGPTDVSILINGENGSGKETVARAIHKISSRAMKPFFSVKCRAMSEQRFQADVFGIGADANAGPSILEQADGGTVLFND
ILTISKTQQLHLLRFLQEGTIETSDGMKKVNVRILTANASDIEKALIDGDFSEELYHYINVLRINVPSLKERASDITLLA
RYYLQEYSKEYNAQAKGYSEEALRALMRYYWPGNVRELMNQIKRAVLMSDSVIIDVPQLDLPKRGDSKRSLKNIREKSER
DALLLVLESHSGQVSNAAKELGVSRATMYRLLNKHNLISEQTV

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=357, Percent_Identity=31.6526610644258, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1788905, Length=344, Percent_Identity=31.6860465116279, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1788550, Length=426, Percent_Identity=31.2206572769953, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=30.5295950155763, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=31.9277108433735, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI87082117, Length=309, Percent_Identity=33.3333333333333, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI87081872, Length=318, Percent_Identity=30.8176100628931, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=31.5457413249211, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789087, Length=297, Percent_Identity=31.6498316498317, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787583, Length=304, Percent_Identity=29.6052631578947, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1786524, Length=314, Percent_Identity=29.9363057324841, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081858, Length=289, Percent_Identity=26.9896193771626, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789828, Length=256, Percent_Identity=25.390625, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49711; Mature: 49580

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQFKMDSVPGSLVVVGGTYEPWLSVLEQVGWKCHQCADLRKVDALLEDIGPCIGIVDL
CCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEC
SHDEFSLNGIANLVSTHKHVRWLAFIREQQLSSDTICQFIVNFCIDFFTAPIPDAQLLST
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IGHQLGMLKLEKKVWPTFGNNQDMGLIGESVPLKRLRDQIKRIGPTDVSILINGENGSGK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCH
ETVARAIHKISSRAMKPFFSVKCRAMSEQRFQADVFGIGADANAGPSILEQADGGTVLFN
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHCCCCEEEEE
DILTISKTQQLHLLRFLQEGTIETSDGMKKVNVRILTANASDIEKALIDGDFSEELYHYI
HHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCHHHHHHHHHCCCHHHHHHHHH
NVLRINVPSLKERASDITLLARYYLQEYSKEYNAQAKGYSEEALRALMRYYWPGNVRELM
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHH
NQIKRAVLMSDSVIIDVPQLDLPKRGDSKRSLKNIREKSERDALLLVLESHSGQVSNAAK
HHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
ELGVSRATMYRLLNKHNLISEQTV
HHCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ATQFKMDSVPGSLVVVGGTYEPWLSVLEQVGWKCHQCADLRKVDALLEDIGPCIGIVDL
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEC
SHDEFSLNGIANLVSTHKHVRWLAFIREQQLSSDTICQFIVNFCIDFFTAPIPDAQLLST
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IGHQLGMLKLEKKVWPTFGNNQDMGLIGESVPLKRLRDQIKRIGPTDVSILINGENGSGK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCH
ETVARAIHKISSRAMKPFFSVKCRAMSEQRFQADVFGIGADANAGPSILEQADGGTVLFN
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHCCCCEEEEE
DILTISKTQQLHLLRFLQEGTIETSDGMKKVNVRILTANASDIEKALIDGDFSEELYHYI
HHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCHHHHHHHHHCCCHHHHHHHHH
NVLRINVPSLKERASDITLLARYYLQEYSKEYNAQAKGYSEEALRALMRYYWPGNVRELM
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHH
NQIKRAVLMSDSVIIDVPQLDLPKRGDSKRSLKNIREKSERDALLLVLESHSGQVSNAAK
HHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
ELGVSRATMYRLLNKHNLISEQTV
HHCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]