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The map label for this gene is dsdC [H]

Identifier: 27363881

GI number: 27363881

Start: 404900

End: 405802

Strand: Reverse

Name: dsdC [H]

Synonym: VV1_0413

Alternate gene names: 27363881

Gene position: 405802-404900 (Counterclockwise)

Preceding gene: 27363884

Following gene: 27363880

Centisome position: 12.36

GC content: 48.84

Gene sequence:

>903_bases
ATGATCAAAAGCACTTATGTATCGGCACTGCATACTTTTGTGGAAGTGGGTAAGTACCCCAGTTTAACCGAGGCTGCAAG
GCAACTTTGCTTAACTACCGGTGCGGTGAGTCAGCAGTTATTACAGCTAGAACAGCAACTTGGTTTTAGTTTGTTTGAAC
GGCACTCTCGCGGTATTCGTTTTACGGAGAAAGGTCGGCAACTTCATCAATGTGCCGCGTTGCACTTTGGGGAAATGGCA
TCGGAAATCCAACGTTTAAAGCAAGAGCAGAATCGCCCACAGGAAGTGCGTCTTAAATTGACTCCTTCTTTTGCCTTCAA
ATGGCTGGTGCCAAAATTGGAAAGCTTTCACCAGCAGTACCCCGATATTCAAATCCAAATTTTTGCCGAAGGGGCTTTGG
TGAACAGTGATACGCGAGATTTTGACCTCGCGATTGATTACCGCCCACACCCGTTTCGTCAAGCCAATACCGAGTTGCTA
TTGGATGAATATTTGCTGCCTGTGATGAACCCCAGATACTTGCAAACACACGCGTGGTTGCACAATGCCGTGTATGCGCT
AGATGAGTGGAGTCAAGTGGTGCTTTTGCACGACGCTATGCCGTGGGAAAACGCGCCAAGGGATTATGAATGGCTTAGTT
GGGTCGCGCAGAGACGGCTCGATTTACCAACCGAAAGAGGACACTTCTTTAACCGGACCGATATGGCGATGTCGGCTGCC
GAAGCGGGTGTAGGGATTGCCATGGCACGCATGGCGCTGATTGATGATGAGTTGCAAACCGGCCGCTTAGTCTCTCCTTT
TCAGCCCATCCGAGCAGAGGCGGGGTACTATTTGATCCACAACAGCAAAAATGACAGCACCGCAGCGTTTACCACTTGGC
TTAAGCAACAAATTTCAAATTGA

Upstream 100 bases:

>100_bases
CCTGATTAGAAACAGCGTGAGTTTCTTAGGTTTACAACTTGGTAACAATCGATATAAATTAATTGCTGCTTATAGAAAAA
CTAAACGCAAGTGGGCAAAA

Downstream 100 bases:

>100_bases
GTGGCAACTCAATAACTAGCTCCTACACTTACTTTTATACCGTGGTCATAACAAATAAATCCAAATCGGTATGACAAGAG
GGGCAGCAAATGAAGTCAGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: D-serine deaminase activator [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MIKSTYVSALHTFVEVGKYPSLTEAARQLCLTTGAVSQQLLQLEQQLGFSLFERHSRGIRFTEKGRQLHQCAALHFGEMA
SEIQRLKQEQNRPQEVRLKLTPSFAFKWLVPKLESFHQQYPDIQIQIFAEGALVNSDTRDFDLAIDYRPHPFRQANTELL
LDEYLLPVMNPRYLQTHAWLHNAVYALDEWSQVVLLHDAMPWENAPRDYEWLSWVAQRRLDLPTERGHFFNRTDMAMSAA
EAGVGIAMARMALIDDELQTGRLVSPFQPIRAEAGYYLIHNSKNDSTAAFTTWLKQQISN

Sequences:

>Translated_300_residues
MIKSTYVSALHTFVEVGKYPSLTEAARQLCLTTGAVSQQLLQLEQQLGFSLFERHSRGIRFTEKGRQLHQCAALHFGEMA
SEIQRLKQEQNRPQEVRLKLTPSFAFKWLVPKLESFHQQYPDIQIQIFAEGALVNSDTRDFDLAIDYRPHPFRQANTELL
LDEYLLPVMNPRYLQTHAWLHNAVYALDEWSQVVLLHDAMPWENAPRDYEWLSWVAQRRLDLPTERGHFFNRTDMAMSAA
EAGVGIAMARMALIDDELQTGRLVSPFQPIRAEAGYYLIHNSKNDSTAAFTTWLKQQISN
>Mature_300_residues
MIKSTYVSALHTFVEVGKYPSLTEAARQLCLTTGAVSQQLLQLEQQLGFSLFERHSRGIRFTEKGRQLHQCAALHFGEMA
SEIQRLKQEQNRPQEVRLKLTPSFAFKWLVPKLESFHQQYPDIQIQIFAEGALVNSDTRDFDLAIDYRPHPFRQANTELL
LDEYLLPVMNPRYLQTHAWLHNAVYALDEWSQVVLLHDAMPWENAPRDYEWLSWVAQRRLDLPTERGHFFNRTDMAMSAA
EAGVGIAMARMALIDDELQTGRLVSPFQPIRAEAGYYLIHNSKNDSTAAFTTWLKQQISN

Specific function: Regulates the expression of the dsd operon for D-serine deaminase (dsdA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788706, Length=296, Percent_Identity=34.1216216216216, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789173, Length=293, Percent_Identity=32.0819112627986, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786448, Length=308, Percent_Identity=27.9220779220779, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790262, Length=170, Percent_Identity=31.1764705882353, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786401, Length=261, Percent_Identity=23.7547892720307, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI157672245, Length=141, Percent_Identity=30.4964539007092, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787589, Length=145, Percent_Identity=28.2758620689655, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=130, Percent_Identity=28.4615384615385, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011781
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34636; Mature: 34636

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKSTYVSALHTFVEVGKYPSLTEAARQLCLTTGAVSQQLLQLEQQLGFSLFERHSRGIR
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
FTEKGRQLHQCAALHFGEMASEIQRLKQEQNRPQEVRLKLTPSFAFKWLVPKLESFHQQY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHC
PDIQIQIFAEGALVNSDTRDFDLAIDYRPHPFRQANTELLLDEYLLPVMNPRYLQTHAWL
CCEEEEEEECCEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
HNAVYALDEWSQVVLLHDAMPWENAPRDYEWLSWVAQRRLDLPTERGHFFNRTDMAMSAA
HHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
EAGVGIAMARMALIDDELQTGRLVSPFQPIRAEAGYYLIHNSKNDSTAAFTTWLKQQISN
HCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKSTYVSALHTFVEVGKYPSLTEAARQLCLTTGAVSQQLLQLEQQLGFSLFERHSRGIR
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
FTEKGRQLHQCAALHFGEMASEIQRLKQEQNRPQEVRLKLTPSFAFKWLVPKLESFHQQY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHC
PDIQIQIFAEGALVNSDTRDFDLAIDYRPHPFRQANTELLLDEYLLPVMNPRYLQTHAWL
CCEEEEEEECCEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
HNAVYALDEWSQVVLLHDAMPWENAPRDYEWLSWVAQRRLDLPTERGHFFNRTDMAMSAA
HHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
EAGVGIAMARMALIDDELQTGRLVSPFQPIRAEAGYYLIHNSKNDSTAAFTTWLKQQISN
HCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592420; 9205837; 9278503 [H]