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The map label for this gene is pgm [H]

Identifier: 27363652

GI number: 27363652

Start: 159086

End: 160735

Strand: Reverse

Name: pgm [H]

Synonym: VV1_0169

Alternate gene names: 27363652

Gene position: 160735-159086 (Counterclockwise)

Preceding gene: 27363653

Following gene: 27363651

Centisome position: 4.9

GC content: 48.3

Gene sequence:

>1650_bases
ATGGCTATGCACCCTCGTGCAGGGCAGAAAGCTCTGCAAGAAGATCTTCACAATATCCCAGCACTCGTTGCTAATTATTT
CCTCCTTCAACCCGATCCAACAAACCCAGCACACAAAGTCGAGTTTGGTACGTCAGGGCATCGTGGTTGTGCGGATAAAT
CCACTTTTAACGAACATCATATTTTAGCGATTGCTCAAGCAGTGGCTGAAGTACGCGCAGAGCAAGGGACAACGGGTCCT
CTTTTTGTGGGTAAAGATACGCATGCGTTGTCTGAGCCAGCGTTTTCTACCGTTGTTGAAGTGCTGATTGCCAATGGCGT
GACCGTGATTGTACAAGAACAAAATGGCTATACCCCAACTCCGGGTATTTCTCATGCGATCCTGACATACAACTTACAAC
ACGAAGAAAAAGCAGACGGTATTGTGATCACTCCGTCTCATAACCCACCACAAGATGGCGGTATCAAATACAATCCGACT
CATGGTGGCCCCGCTGAAGGCGAGCTAACACAGCGAATTGAGAATCGTGCAAACGTACTCATCGCAGAGGGGTTGCAGGG
TGTTAAGCGTATGCCTTTGGCGCAAGCAAAAGCGTCATCGCTGTTTGTAGAGCAAGATCTGGTCAAACCTTATGTCGATG
ACTTGGTGAATGTAATCGATATGGCTGCCATCCAAAAAGCAGGCCTGAAACTGGGTGTCGATCCTCTTGGCGGCAGTGGC
ATTGATTATTGGCGTCAGATTGGTAAAGCATACAATTTAGATCTTACTTTAGTGAGTGAAGCCATTGACCCTTCTTTCCA
GTTTATGTCATTGGATAAAGATGGTGTGGTGCGTATGGACTGCTCTTCTCCCTACGCAATGGCTGGATTGCTGGCGCTAA
AAGATCAGTATGATCTCGCGTTTGGCAATGACCCAGATTACGATCGCCATGGTATTGTCACGCCAACAAAAGGCTTGATG
AATCCGAACCACTTCTTAGCTGTTTGTATTGATTATCTATACCGTCATCGTCAAGGTTGGGCTGCGGATGTGGCAGTGGG
TAAAACCCTAGTTTCTAGCGCCATGATTGACCGAGTGGTGGCCGATCTTGGCCGTGAGCTATGTGAAGTACCGGTTGGCT
TCAAATGGTTTGTGGATGGGTTGTACAACGGTAAGTTTGGCTTTGGTGGCGAAGAGAGTGCGGGAGCCTCATTCTTGCGC
CAAGATGGTACACCATGGTCGACAGACAAAGATGGCATCATTCTCTGTTTACTGGCTGCGGAAATCACCGCAGTGACCGG
TAAAAACCCGCAGCAATATTACGACGAGCTGGCGGCTAAACATGGGGAGTCTCAGTACAGCCGAATCCAAGCGGTTGCCA
ATGGTCCTCAGAAAGAGGTACTGAAGAAGCTCTCTGCTGAAATGGTGAAGGCAGAAACTTTAGCAGGTGATGAGATTACC
GCGAGACTGACCCATGCTCCTGGTAATGGCGCAGCGATTGGTGGTCTAAAAGTGACAACTGCGAACGGTTGGTTTGCTGC
GCGTCCATCGGGTACTGAAGATATCTATAAGATCTATTGTGAGAGCTTCAAAGGCGCAGAGCACCTCAAACAAATTGAGT
TGGAAGCGCAAGAGATTGTCAATCAAGTCTTTGCCGAAGCAGGTCTATAA

Upstream 100 bases:

>100_bases
TTCAATTTAAGAAACCTGATAGAAGCCTCATAATGCGCAAGATTATGCCGATATTATGAGGCTTTTTTGTTTGAGTATAT
TTTAAGAAAGGATGTCATTA

Downstream 100 bases:

>100_bases
TTCTTTACGGCTGATAATGGCTTTCCAATGATAATTAAAATCCCAAACACAGTGTTTGGGATTTTTATTGTCGGAATAAA
ATTAAATTCATATGTCGAAT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MAMHPRAGQKALQEDLHNIPALVANYFLLQPDPTNPAHKVEFGTSGHRGCADKSTFNEHHILAIAQAVAEVRAEQGTTGP
LFVGKDTHALSEPAFSTVVEVLIANGVTVIVQEQNGYTPTPGISHAILTYNLQHEEKADGIVITPSHNPPQDGGIKYNPT
HGGPAEGELTQRIENRANVLIAEGLQGVKRMPLAQAKASSLFVEQDLVKPYVDDLVNVIDMAAIQKAGLKLGVDPLGGSG
IDYWRQIGKAYNLDLTLVSEAIDPSFQFMSLDKDGVVRMDCSSPYAMAGLLALKDQYDLAFGNDPDYDRHGIVTPTKGLM
NPNHFLAVCIDYLYRHRQGWAADVAVGKTLVSSAMIDRVVADLGRELCEVPVGFKWFVDGLYNGKFGFGGEESAGASFLR
QDGTPWSTDKDGIILCLLAAEITAVTGKNPQQYYDELAAKHGESQYSRIQAVANGPQKEVLKKLSAEMVKAETLAGDEIT
ARLTHAPGNGAAIGGLKVTTANGWFAARPSGTEDIYKIYCESFKGAEHLKQIELEAQEIVNQVFAEAGL

Sequences:

>Translated_549_residues
MAMHPRAGQKALQEDLHNIPALVANYFLLQPDPTNPAHKVEFGTSGHRGCADKSTFNEHHILAIAQAVAEVRAEQGTTGP
LFVGKDTHALSEPAFSTVVEVLIANGVTVIVQEQNGYTPTPGISHAILTYNLQHEEKADGIVITPSHNPPQDGGIKYNPT
HGGPAEGELTQRIENRANVLIAEGLQGVKRMPLAQAKASSLFVEQDLVKPYVDDLVNVIDMAAIQKAGLKLGVDPLGGSG
IDYWRQIGKAYNLDLTLVSEAIDPSFQFMSLDKDGVVRMDCSSPYAMAGLLALKDQYDLAFGNDPDYDRHGIVTPTKGLM
NPNHFLAVCIDYLYRHRQGWAADVAVGKTLVSSAMIDRVVADLGRELCEVPVGFKWFVDGLYNGKFGFGGEESAGASFLR
QDGTPWSTDKDGIILCLLAAEITAVTGKNPQQYYDELAAKHGESQYSRIQAVANGPQKEVLKKLSAEMVKAETLAGDEIT
ARLTHAPGNGAAIGGLKVTTANGWFAARPSGTEDIYKIYCESFKGAEHLKQIELEAQEIVNQVFAEAGL
>Mature_548_residues
AMHPRAGQKALQEDLHNIPALVANYFLLQPDPTNPAHKVEFGTSGHRGCADKSTFNEHHILAIAQAVAEVRAEQGTTGPL
FVGKDTHALSEPAFSTVVEVLIANGVTVIVQEQNGYTPTPGISHAILTYNLQHEEKADGIVITPSHNPPQDGGIKYNPTH
GGPAEGELTQRIENRANVLIAEGLQGVKRMPLAQAKASSLFVEQDLVKPYVDDLVNVIDMAAIQKAGLKLGVDPLGGSGI
DYWRQIGKAYNLDLTLVSEAIDPSFQFMSLDKDGVVRMDCSSPYAMAGLLALKDQYDLAFGNDPDYDRHGIVTPTKGLMN
PNHFLAVCIDYLYRHRQGWAADVAVGKTLVSSAMIDRVVADLGRELCEVPVGFKWFVDGLYNGKFGFGGEESAGASFLRQ
DGTPWSTDKDGIILCLLAAEITAVTGKNPQQYYDELAAKHGESQYSRIQAVANGPQKEVLKKLSAEMVKAETLAGDEITA
RLTHAPGNGAAIGGLKVTTANGWFAARPSGTEDIYKIYCESFKGAEHLKQIELEAQEIVNQVFAEAGL

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI133922562, Length=440, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI290463102, Length=479, Percent_Identity=25.8872651356994, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI21361621, Length=470, Percent_Identity=25.1063829787234, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1786904, Length=547, Percent_Identity=70.018281535649, Blast_Score=785, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=448, Percent_Identity=27.2321428571429, Blast_Score=89, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323752, Length=573, Percent_Identity=26.7015706806283, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6322722, Length=495, Percent_Identity=28.6868686868687, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17864244, Length=469, Percent_Identity=26.0127931769723, Blast_Score=106, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59233; Mature: 59101

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMHPRAGQKALQEDLHNIPALVANYFLLQPDPTNPAHKVEFGTSGHRGCADKSTFNEHH
CCCCCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCHH
ILAIAQAVAEVRAEQGTTGPLFVGKDTHALSEPAFSTVVEVLIANGVTVIVQEQNGYTPT
HHHHHHHHHHHHHHCCCCCCEEECCCCCHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCC
PGISHAILTYNLQHEEKADGIVITPSHNPPQDGGIKYNPTHGGPAEGELTQRIENRANVL
CCCCEEEEEEEECCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCEE
IAEGLQGVKRMPLAQAKASSLFVEQDLVKPYVDDLVNVIDMAAIQKAGLKLGVDPLGGSG
EHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
IDYWRQIGKAYNLDLTLVSEAIDPSFQFMSLDKDGVVRMDCSSPYAMAGLLALKDQYDLA
HHHHHHHCHHCCCEEEEEHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHCCCCCEE
FGNDPDYDRHGIVTPTKGLMNPNHFLAVCIDYLYRHRQGWAADVAVGKTLVSSAMIDRVV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
ADLGRELCEVPVGFKWFVDGLYNGKFGFGGEESAGASFLRQDGTPWSTDKDGIILCLLAA
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEEEH
EITAVTGKNPQQYYDELAAKHGESQYSRIQAVANGPQKEVLKKLSAEMVKAETLAGDEIT
HHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEE
ARLTHAPGNGAAIGGLKVTTANGWFAARPSGTEDIYKIYCESFKGAEHLKQIELEAQEIV
EEEEECCCCCCEECCEEEEECCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NQVFAEAGL
HHHHHHCCC
>Mature Secondary Structure 
AMHPRAGQKALQEDLHNIPALVANYFLLQPDPTNPAHKVEFGTSGHRGCADKSTFNEHH
CCCCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCHH
ILAIAQAVAEVRAEQGTTGPLFVGKDTHALSEPAFSTVVEVLIANGVTVIVQEQNGYTPT
HHHHHHHHHHHHHHCCCCCCEEECCCCCHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCC
PGISHAILTYNLQHEEKADGIVITPSHNPPQDGGIKYNPTHGGPAEGELTQRIENRANVL
CCCCEEEEEEEECCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCEE
IAEGLQGVKRMPLAQAKASSLFVEQDLVKPYVDDLVNVIDMAAIQKAGLKLGVDPLGGSG
EHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
IDYWRQIGKAYNLDLTLVSEAIDPSFQFMSLDKDGVVRMDCSSPYAMAGLLALKDQYDLA
HHHHHHHCHHCCCEEEEEHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHCCCCCEE
FGNDPDYDRHGIVTPTKGLMNPNHFLAVCIDYLYRHRQGWAADVAVGKTLVSSAMIDRVV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
ADLGRELCEVPVGFKWFVDGLYNGKFGFGGEESAGASFLRQDGTPWSTDKDGIILCLLAA
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEEEH
EITAVTGKNPQQYYDELAAKHGESQYSRIQAVANGPQKEVLKKLSAEMVKAETLAGDEIT
HHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEE
ARLTHAPGNGAAIGGLKVTTANGWFAARPSGTEDIYKIYCESFKGAEHLKQIELEAQEIV
EEEEECCCCCCEECCEEEEECCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NQVFAEAGL
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]