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The map label for this gene is sucC [H]

Identifier: 27363638

GI number: 27363638

Start: 142616

End: 143782

Strand: Reverse

Name: sucC [H]

Synonym: VV1_0155

Alternate gene names: 27363638

Gene position: 143782-142616 (Counterclockwise)

Preceding gene: 27363639

Following gene: 27363637

Centisome position: 4.38

GC content: 46.62

Gene sequence:

>1167_bases
ATGAATTTGCATGAATACCAAGCCAAACAGCTGTTTGCAGAATTCGGTTTGCCGGTACCAGAAGGTTATGCTTGTGATAC
ACCTCAAGAAGCATTTGAAGCTGCTGGCCGCATTAGCACCGCGAAGAAAGTTGTAAAATGTCAGGTTCACGCAGGTGGCC
GCGGTAAAGCGGGTGGCGTAGAGCTTCACGATACGAAAGAAGGCGTGAAAGAATTTGCACAAAAATGGCTTGGCAAAAAC
CTGGTAACTTATCAGACAGATGCGAATGGTCAGCCAGTAACAAAAATTTTGGTTGAAGAAGCGTCCAATATTGCCAACGA
GCTATACTTGGGTGCTGTCGTTGACCGTGCAACACGTAAAGTCGTTTTCATGGCCTCAACTGAAGGCGGTGTGGAAATCG
AAAAAGTTGCAGAAGAAACACCTGAACTGATTCACAAAGCGGCTATTGATCCACTGGTAGGCCCTCAGGCTTATCAAGGT
CGTGAGCTTGCATTTAAACTTGGTCTTCAAGGCGATCAAATTAAGCAGTTTGTGAAAATCTTCATGGGTTTGGGTGAAAT
GTTCACTCAATACGATCTCGCTCTTCTTGAAATCAACCCACTTGTGATTACTGGTGAAGGCAACCTACTTTGTCTAGATG
GTAAGATCAACATCGACTCAAATGCGCTTTACCGCCAACCTAAACTGCGTGAAATGCACGATCCTTCTCAAGAAGATAAG
CGTGAAGCTCATGCGGCGCAGTGGGAACTGAACTACGTAGCACTTGATGGTAACGTCGGCTGTATGGTGAACGGTGCAGG
CCTTGCAATGGGTACTATGGACATCGTAAACCTACACGGTGGCAAACCAGCCAACTTCTTGGATGTAGGTGGCGGCGCGA
CAAAAGAGCGTGTAGCAGAGGCATTCAAGATCATCCTTTCTGATGACAATGTAAAAGCCGTTTTGGTGAACATCTTTGGT
GGTATTGTTCGTTGTGACATGATCGCAGAAGGTATCATCGGCGCGGTAAAAGAAGTTGGTGTAAGCGTACCCGTTGTTGT
ACGCCTTGAAGGTACTAATGCGGATCTTGGCCGCAAAGTACTGGCAGAGTCAGGTTTGGATATCATTGCAGCAGAATCAC
TAACAGATGCTGCTCAGAAAGTAGTTGCTGCGGCGGAGGGCAAATAA

Upstream 100 bases:

>100_bases
TTAGCAGTTTATTTGAGAAGACCCTACAGGCGTCGCACTGTTAATCGTGACGTTATGGAAATAATAAATCCCTTAAGGGA
AGAACAAACGGAATATCAAA

Downstream 100 bases:

>100_bases
TGTCTGTATTAATTAACAAAGACACCAAAGTAATCTGTCAGGGTTTCACAGGCGGTCAAGGTACTTTCCACTCAGAGCAA
GCGCTAGCTTATGGCACGCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTYQTDANGQPVTKILVEEASNIANELYLGAVVDRATRKVVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQG
RELAFKLGLQGDQIKQFVKIFMGLGEMFTQYDLALLEINPLVITGEGNLLCLDGKINIDSNALYRQPKLREMHDPSQEDK
REAHAAQWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDDNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNADLGRKVLAESGLDIIAAESLTDAAQKVVAAAEGK

Sequences:

>Translated_388_residues
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTYQTDANGQPVTKILVEEASNIANELYLGAVVDRATRKVVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQG
RELAFKLGLQGDQIKQFVKIFMGLGEMFTQYDLALLEINPLVITGEGNLLCLDGKINIDSNALYRQPKLREMHDPSQEDK
REAHAAQWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDDNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNADLGRKVLAESGLDIIAAESLTDAAQKVVAAAEGK
>Mature_388_residues
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKEFAQKWLGKN
LVTYQTDANGQPVTKILVEEASNIANELYLGAVVDRATRKVVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQG
RELAFKLGLQGDQIKQFVKIFMGLGEMFTQYDLALLEINPLVITGEGNLLCLDGKINIDSNALYRQPKLREMHDPSQEDK
REAHAAQWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDDNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNADLGRKVLAESGLDIIAAESLTDAAQKVVAAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=46.0559796437659, Blast_Score=352, Evalue=3e-97,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.6475195822454, Blast_Score=315, Evalue=3e-86,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=44.8467966573816, Blast_Score=300, Evalue=1e-81,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=77.5773195876289, Blast_Score=601, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=45.360824742268, Blast_Score=318, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=42.4936386768448, Blast_Score=310, Evalue=7e-85,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=42.3469387755102, Blast_Score=328, Evalue=8e-91,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=43.5114503816794, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=43.5114503816794, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI21356231, Length=395, Percent_Identity=43.5443037974684, Blast_Score=307, Evalue=7e-84,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=43.6548223350254, Blast_Score=305, Evalue=2e-83,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=43.6548223350254, Blast_Score=305, Evalue=2e-83,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41525; Mature: 41525

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHEEEEEEEECCCCCCCCCE
ELHDTKEGVKEFAQKWLGKNLVTYQTDANGQPVTKILVEEASNIANELYLGAVVDRATRK
EEHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQGRELAFKLGLQGDQIKQFVKI
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FMGLGEMFTQYDLALLEINPLVITGEGNLLCLDGKINIDSNALYRQPKLREMHDPSQEDK
HHHHHHHHHHHCEEEEEECCEEEECCCCEEEECCEEECCCCHHCCCCCHHHHCCCCHHHH
REAHAAQWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDDNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNADLGRKV
HHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
LAESGLDIIAAESLTDAAQKVVAAAEGK
HHHCCCCEEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHEEEEEEEECCCCCCCCCE
ELHDTKEGVKEFAQKWLGKNLVTYQTDANGQPVTKILVEEASNIANELYLGAVVDRATRK
EEHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQGRELAFKLGLQGDQIKQFVKI
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FMGLGEMFTQYDLALLEINPLVITGEGNLLCLDGKINIDSNALYRQPKLREMHDPSQEDK
HHHHHHHHHHHCEEEEEECCEEEECCCCEEEECCEEECCCCHHCCCCCHHHHCCCCHHHH
REAHAAQWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDDNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNADLGRKV
HHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
LAESGLDIIAAESLTDAAQKVVAAAEGK
HHHCCCCEEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA