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The map label for this gene is ppiD [H]

Identifier: 27363507

GI number: 27363507

Start: 18578

End: 20437

Strand: Reverse

Name: ppiD [H]

Synonym: VV1_0018

Alternate gene names: 27363507

Gene position: 20437-18578 (Counterclockwise)

Preceding gene: 27363508

Following gene: 326423649

Centisome position: 0.62

GC content: 45.54

Gene sequence:

>1860_bases
ATGATGGATCGATTGCGCGAAGGCGTGAATAGCATCGCGGTTAAAATTATCCTAGGATTGATCATCCTATCGTTTGTCTT
TGCAGGTGTCGGCAGTTACCTCGTGAGTGGTAGTAGTAACTCTGCAGCAAAAGTTGGCAATGTCGAAATCGGTCGTGGTG
AGTTTGAAATGGCTTACCAAAACGAGCGTAATCGTATGCAGTCGCAACTAGGAGATTACTTTTCTCAACTCCTTGCTGAC
CCTGCTTACGTAGAGTCTTTCCGTAAATCGGTATTAGACCGCATGATTAACGACGTTTTGCTTGATCAGCATGCAGAATC
ATTAGGTTTACGCATCAGTGATGCTCAAGTAAGAAGCATGATTCTAGCGATGCCAGAATTCCAGCAAGACGGTAAATTCA
ACCAAGACGTCTACCAAGCGACCCTACGTCGCGCGGGTTACTCACCAGATTCTTTTGCAGAGTACATGCGTCGTGAACTG
ATTCGTTCTCAATTGCTTGATGCACTACAAACCAGCGAATTTACCCTACCAGGTGAAGTGGATGCAGAAGGTAAACTGTT
TACTCAAACACGTGATGTTCGTACGGTGACGCTAAATATTCGCGACTTTGCAGATAAAGTGACGTTGACAGAAGAAGATA
TCCAAAAGTACTACGATGAAAACAAATCACGCTTTACTCGCCCTGAGCAGGTGAAGGTGTCTTACATCGAGTTAGCGGCG
GATTCACTCAAGCAGCAAATCACCATTTCTGATGACGAAGTGAAACAGTACTATCAAGAGCACCTTGATAAGTATTCCTC
TGAGGAGCAGCGTCGAGTGGCTCATATCCTCATTGAGGGGGATGACCAAGCTAAAGCACAAGCAATTTTAGACGAATTGA
ACGCTGGCGCGGATTTTGCGACACTAGCTCAAGAGAAATCAGACGATTTTGGCAGTGCTGATAACGGCGGTGAACTTGGT
TGGATTGAACGTGATGTGATGGATCCAGCGTTTGAAGAAGCGGCGTTTGCGCTAAAAAATGTTGGCGATGTCACTGGCTT
GGTGAAGTCTGACTTCGGCTACCACATCATCAAACTCGAAGAGCTAAAAGAACCGGTTGTGAAGCCATTTAGCGACGTTG
CTGCGCAAATCAAACAAGAAATGATCGACCAGAAAGCCGTCGACCAATTCTATGAGTTGCAAAGTGAGCTAGAGAAAGTG
GCATTCGAATACCCAGATTCTTTAGAAGAAGCATCAAAAGCGGTGGGTCAACAAGTGAAACACACTGACTTTATCTCTCA
AGTTGATGCGCCTGAAATTCTTCGTACACCTGCGGTTACTCAAGCGATTACCAGTCCAGAAGTTAAGTTGGATGGCCTGA
ACTCAGAAGCGATTGAAATTGCCCCTGAACACATCATCGTTGTTCGTGTTGATGATGCTCGTGATGAGACGGTGTTACCT
TTGACTGAGGTGCAAGACCAAGTAGCTGCAGAGCTTTCTCAAGTGAAAGGTGAGCAACAAGCACTTGAGCTGGGAACCGA
AGTCGTGACAGCTCTGAAAGCGGGTAACACAGCTATTTTACAAGAAAAAGGCTTATCGTTTGGTGAGTTAGAGAAGATTG
ATCGTCGTTCTCCTTTAGCTCAGACCGTGTTTGCTATGGCAAAACCAGCAGCAGGTAATGCGGTATACGGCCAAAGTAAA
GATATGGAAGGCAATGTTGTTGTCGTGGCGCTTGAAAAAGTAGAAGAGAGCTTAGAGCCTGTACTAGCACAGCAAATTTC
AGTGCAACTGCAACGCGTCTCTGCACAGCGTGACTTGAGTTCTATCGTCGCGATTCTTCGTGCTAACACCGATATTGAAT
ACTTTGTTGTGAGCAACTAA

Upstream 100 bases:

>100_bases
TTATGCGCATCCTACTGATGCGCATTTCTTTTTTCTGGTATTATCGCGTGATTACATTTCAAGAGAAGCGTTGGCTTCGT
GAGTGGAGAGCAGTTTAGTT

Downstream 100 bases:

>100_bases
TCGTTCGGTGTGCAACTGATATGTAACTAAAAACAGGTCGCTTTCGCGGCCTGTTTTATTTTTGTCTCTTGTCTGTTTTG
TGCTCTCGCTGGGTTAGGTA

Product: peptidyl-prolyl cis-trans isomerase ppiD

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MMDRLREGVNSIAVKIILGLIILSFVFAGVGSYLVSGSSNSAAKVGNVEIGRGEFEMAYQNERNRMQSQLGDYFSQLLAD
PAYVESFRKSVLDRMINDVLLDQHAESLGLRISDAQVRSMILAMPEFQQDGKFNQDVYQATLRRAGYSPDSFAEYMRREL
IRSQLLDALQTSEFTLPGEVDAEGKLFTQTRDVRTVTLNIRDFADKVTLTEEDIQKYYDENKSRFTRPEQVKVSYIELAA
DSLKQQITISDDEVKQYYQEHLDKYSSEEQRRVAHILIEGDDQAKAQAILDELNAGADFATLAQEKSDDFGSADNGGELG
WIERDVMDPAFEEAAFALKNVGDVTGLVKSDFGYHIIKLEELKEPVVKPFSDVAAQIKQEMIDQKAVDQFYELQSELEKV
AFEYPDSLEEASKAVGQQVKHTDFISQVDAPEILRTPAVTQAITSPEVKLDGLNSEAIEIAPEHIIVVRVDDARDETVLP
LTEVQDQVAAELSQVKGEQQALELGTEVVTALKAGNTAILQEKGLSFGELEKIDRRSPLAQTVFAMAKPAAGNAVYGQSK
DMEGNVVVVALEKVEESLEPVLAQQISVQLQRVSAQRDLSSIVAILRANTDIEYFVVSN

Sequences:

>Translated_619_residues
MMDRLREGVNSIAVKIILGLIILSFVFAGVGSYLVSGSSNSAAKVGNVEIGRGEFEMAYQNERNRMQSQLGDYFSQLLAD
PAYVESFRKSVLDRMINDVLLDQHAESLGLRISDAQVRSMILAMPEFQQDGKFNQDVYQATLRRAGYSPDSFAEYMRREL
IRSQLLDALQTSEFTLPGEVDAEGKLFTQTRDVRTVTLNIRDFADKVTLTEEDIQKYYDENKSRFTRPEQVKVSYIELAA
DSLKQQITISDDEVKQYYQEHLDKYSSEEQRRVAHILIEGDDQAKAQAILDELNAGADFATLAQEKSDDFGSADNGGELG
WIERDVMDPAFEEAAFALKNVGDVTGLVKSDFGYHIIKLEELKEPVVKPFSDVAAQIKQEMIDQKAVDQFYELQSELEKV
AFEYPDSLEEASKAVGQQVKHTDFISQVDAPEILRTPAVTQAITSPEVKLDGLNSEAIEIAPEHIIVVRVDDARDETVLP
LTEVQDQVAAELSQVKGEQQALELGTEVVTALKAGNTAILQEKGLSFGELEKIDRRSPLAQTVFAMAKPAAGNAVYGQSK
DMEGNVVVVALEKVEESLEPVLAQQISVQLQRVSAQRDLSSIVAILRANTDIEYFVVSN
>Mature_619_residues
MMDRLREGVNSIAVKIILGLIILSFVFAGVGSYLVSGSSNSAAKVGNVEIGRGEFEMAYQNERNRMQSQLGDYFSQLLAD
PAYVESFRKSVLDRMINDVLLDQHAESLGLRISDAQVRSMILAMPEFQQDGKFNQDVYQATLRRAGYSPDSFAEYMRREL
IRSQLLDALQTSEFTLPGEVDAEGKLFTQTRDVRTVTLNIRDFADKVTLTEEDIQKYYDENKSRFTRPEQVKVSYIELAA
DSLKQQITISDDEVKQYYQEHLDKYSSEEQRRVAHILIEGDDQAKAQAILDELNAGADFATLAQEKSDDFGSADNGGELG
WIERDVMDPAFEEAAFALKNVGDVTGLVKSDFGYHIIKLEELKEPVVKPFSDVAAQIKQEMIDQKAVDQFYELQSELEKV
AFEYPDSLEEASKAVGQQVKHTDFISQVDAPEILRTPAVTQAITSPEVKLDGLNSEAIEIAPEHIIVVRVDDARDETVLP
LTEVQDQVAAELSQVKGEQQALELGTEVVTALKAGNTAILQEKGLSFGELEKIDRRSPLAQTVFAMAKPAAGNAVYGQSK
DMEGNVVVVALEKVEESLEPVLAQQISVQLQRVSAQRDLSSIVAILRANTDIEYFVVSN

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=625, Percent_Identity=38.88, Blast_Score=425, Evalue=1e-120,
Organism=Escherichia coli, GI1786238, Length=93, Percent_Identity=41.9354838709677, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68837; Mature: 68837

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDRLREGVNSIAVKIILGLIILSFVFAGVGSYLVSGSSNSAAKVGNVEIGRGEFEMAYQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHH
NERNRMQSQLGDYFSQLLADPAYVESFRKSVLDRMINDVLLDQHAESLGLRISDAQVRSM
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHH
ILAMPEFQQDGKFNQDVYQATLRRAGYSPDSFAEYMRRELIRSQLLDALQTSEFTLPGEV
HHHCCCHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DAEGKLFTQTRDVRTVTLNIRDFADKVTLTEEDIQKYYDENKSRFTRPEQVKVSYIELAA
CCCCCEEEECCCEEEEEEEHHHHHHHHCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHH
DSLKQQITISDDEVKQYYQEHLDKYSSEEQRRVAHILIEGDDQAKAQAILDELNAGADFA
HHHHHEECCCHHHHHHHHHHHHHHHCCHHHHHEEEEEEECCCHHHHHHHHHHHCCCCCHH
TLAQEKSDDFGSADNGGELGWIERDVMDPAFEEAAFALKNVGDVTGLVKSDFGYHIIKLE
HHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
ELKEPVVKPFSDVAAQIKQEMIDQKAVDQFYELQSELEKVAFEYPDSLEEASKAVGQQVK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
HTDFISQVDAPEILRTPAVTQAITSPEVKLDGLNSEAIEIAPEHIIVVRVDDARDETVLP
HHHHHHHCCCHHHHHCCHHHHHHCCCCEEECCCCCCCEEECCCEEEEEEECCCCCCCCCC
LTEVQDQVAAELSQVKGEQQALELGTEVVTALKAGNTAILQEKGLSFGELEKIDRRSPLA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHCCCHHH
QTVFAMAKPAAGNAVYGQSKDMEGNVVVVALEKVEESLEPVLAQQISVQLQRVSAQRDLS
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIVAILRANTDIEYFVVSN
HHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MMDRLREGVNSIAVKIILGLIILSFVFAGVGSYLVSGSSNSAAKVGNVEIGRGEFEMAYQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHH
NERNRMQSQLGDYFSQLLADPAYVESFRKSVLDRMINDVLLDQHAESLGLRISDAQVRSM
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHH
ILAMPEFQQDGKFNQDVYQATLRRAGYSPDSFAEYMRRELIRSQLLDALQTSEFTLPGEV
HHHCCCHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DAEGKLFTQTRDVRTVTLNIRDFADKVTLTEEDIQKYYDENKSRFTRPEQVKVSYIELAA
CCCCCEEEECCCEEEEEEEHHHHHHHHCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHH
DSLKQQITISDDEVKQYYQEHLDKYSSEEQRRVAHILIEGDDQAKAQAILDELNAGADFA
HHHHHEECCCHHHHHHHHHHHHHHHCCHHHHHEEEEEEECCCHHHHHHHHHHHCCCCCHH
TLAQEKSDDFGSADNGGELGWIERDVMDPAFEEAAFALKNVGDVTGLVKSDFGYHIIKLE
HHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
ELKEPVVKPFSDVAAQIKQEMIDQKAVDQFYELQSELEKVAFEYPDSLEEASKAVGQQVK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
HTDFISQVDAPEILRTPAVTQAITSPEVKLDGLNSEAIEIAPEHIIVVRVDDARDETVLP
HHHHHHHCCCHHHHHCCHHHHHHCCCCEEECCCCCCCEEECCCEEEEEEECCCCCCCCCC
LTEVQDQVAAELSQVKGEQQALELGTEVVTALKAGNTAILQEKGLSFGELEKIDRRSPLA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHCCCHHH
QTVFAMAKPAAGNAVYGQSKDMEGNVVVVALEKVEESLEPVLAQQISVQLQRVSAQRDLS
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIVAILRANTDIEYFVVSN
HHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]