Click here to switch to the map view.

The map label for this gene is serC [H]

Identifier: 270000551

GI number: 270000551

Start: 3059227

End: 3060336

Strand: Reverse

Name: serC [H]

Synonym: BA_3321

Alternate gene names: 270000551

Gene position: 3060336-3059227 (Counterclockwise)

Preceding gene: 30263233

Following gene: 30263231

Centisome position: 58.55

GC content: 36.31

Gene sequence:

>1110_bases
ATGAGAAATAGGGAGGTTATTAGGGTGATGGAGAGAGTGTATAATTTTTCAGCTGGACCATCAATACTCCCTTTGCCAGT
TTTAGAAAAAGTGCAAAAGGAGCTTGTAAATTATAACGGGACAGGCATGTCTATTATGGAAATGAGTCACCGATCTTCTT
ATTTTCAAAGTATTATAGATGAAGCGGGTAGCTTACTTCGTGAATTAATGAACATTCCTGATGAGTATGAAGTATTGTTT
TTACAAGGTGGTGCTTCATTACAATTCTCTATGATACCGTTAAATTTAATGAATACGTATAAAAAAGCAGGGTACGTATT
GACTGGTTCATGGTCTAAAAAGGCACTGCAAGAAGCTGAAAAAGTTGGAGAAGTACAAGTGATTGCTTCTTCTGAAAATG
AGAAGTTTACTACAATTCCTAAACTGGATGGTTTATTAGGCGATGAAAAACTAGATTATGTACATATAACAACGAATAAT
ACAATAGAGGGTACGAAATATGTGGACATTCCACATGTAGATAAAGTACCACTCGTTGCGGATATGTCCCCAAATATTTT
ATCAGAACGATATGATGTTTCAAAGTTTGGTCTTATATATGCGGGAGCGCAAAAGAATCTAGGGCCAGCGGGCTTAACGA
TTGCAATTATAAAAAGAGATTTAATTGGAGGAGCAGATCGTTATTGTCCTACAATGTTAAACTATGAAACTTACAGTAAA
AATAACTCCTTATATAATACACTGCCGTCCTTTAGTATTTACGTAACAAAACTTGTATTAGAGTGGTTAAAAGAGCAAGG
CGGAGTATCTGCGATTGAAGAACAAAATAAAATGAAATCTTCACTTCTTTACAATTTCTTAGATGAATCAAAATTGCTTA
CTTCACCAGTTGATCCTGCGTATCGGTCACTTATGAACATTCCGTTTACAACGCCGTCAGAAGAGCTGAACAATGAGTTT
TTACAAAAAGCGAAAGAACGCGGCCTTGTTACGTTAAAAGGACATCGATCAGTCGGTGGTATGCGCGCTAGTATTTACAA
TGCGATGCCAGTACAAGGCGTACAGCAATTGGTAAATTATATGAAGGAATTTGAGCTTGAGAATAGATAG

Upstream 100 bases:

>100_bases
TTGCAAGCGATTCCATTGCGTCTTACGCCGTAATAATAGAAAACAAATTGACCGTGTCTTGTATTGTAGGGTATAATTCA
GAAAGTTTAAAAAATAAAAG

Downstream 100 bases:

>100_bases
GGAGATGGGGATATGTTTCGTGTTCAAACGTTAAATCAAATAGCAGAAAAAGGTTTGCAAGTACTTGGCGGAGAGCGTTA
TGAAGTAGGGGAGAGAATCA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MRNREVIRVMERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLF
LQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGDEKLDYVHITTNN
TIEGTKYVDIPHVDKVPLVADMSPNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSK
NNSLYNTLPSFSIYVTKLVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLLTSPVDPAYRSLMNIPFTTPSEELNNEF
LQKAKERGLVTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR

Sequences:

>Translated_369_residues
MRNREVIRVMERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLF
LQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGDEKLDYVHITTNN
TIEGTKYVDIPHVDKVPLVADMSPNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSK
NNSLYNTLPSFSIYVTKLVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLLTSPVDPAYRSLMNIPFTTPSEELNNEF
LQKAKERGLVTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR
>Mature_369_residues
MRNREVIRVMERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLF
LQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGDEKLDYVHITTNN
TIEGTKYVDIPHVDKVPLVADMSPNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSK
NNSLYNTLPSFSIYVTKLVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLLTSPVDPAYRSLMNIPFTTPSEELNNEF
LQKAKERGLVTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=47.0914127423823, Blast_Score=334, Evalue=1e-91,
Organism=Homo sapiens, GI10863955, Length=356, Percent_Identity=41.8539325842697, Blast_Score=281, Evalue=7e-76,
Organism=Escherichia coli, GI1787136, Length=366, Percent_Identity=42.6229508196721, Blast_Score=311, Evalue=5e-86,
Organism=Caenorhabditis elegans, GI17506897, Length=360, Percent_Identity=45, Blast_Score=322, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6324758, Length=391, Percent_Identity=41.1764705882353, Blast_Score=289, Evalue=6e-79,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=48.2093663911846, Blast_Score=336, Evalue=2e-92,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 41503; Mature: 41503

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNREVIRVMERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIID
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EAGSLLRELMNIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAE
HHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECHHHHHHHHHCCEEEECCCHHHHHHHHH
KVGEVQVIASSENEKFTTIPKLDGLLGDEKLDYVHITTNNTIEGTKYVDIPHVDKVPLVA
HCCCEEEEECCCCCCEEECCHHHCCCCCCCCCEEEEEECCEECCCEEECCCCCCCCCEEE
DMSPNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSK
CCCCHHHHHHCCHHHCCEEEECCCCCCCCCCCEEEEEHHHHCCCCCHHCCHHCCCCCCCC
NNSLYNTLPSFSIYVTKLVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLLTSPVDPA
CCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHH
YRSLMNIPFTTPSEELNNEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPVQGVQQLVNY
HHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHH
MKEFELENR
HHHHCCCCC
>Mature Secondary Structure
MRNREVIRVMERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIID
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EAGSLLRELMNIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAE
HHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECHHHHHHHHHCCEEEECCCHHHHHHHHH
KVGEVQVIASSENEKFTTIPKLDGLLGDEKLDYVHITTNNTIEGTKYVDIPHVDKVPLVA
HCCCEEEEECCCCCCEEECCHHHCCCCCCCCCEEEEEECCEECCCEEECCCCCCCCCEEE
DMSPNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSK
CCCCHHHHHHCCHHHCCEEEECCCCCCCCCCCEEEEEHHHHCCCCCHHCCHHCCCCCCCC
NNSLYNTLPSFSIYVTKLVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLLTSPVDPA
CCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHH
YRSLMNIPFTTPSEELNNEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPVQGVQQLVNY
HHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHH
MKEFELENR
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA