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The map label for this gene is treA [H]

Identifier: 262192855

GI number: 262192855

Start: 1490355

End: 1492178

Strand: Reverse

Name: treA [H]

Synonym: BMA10247_A1543

Alternate gene names: 262192855

Gene position: 1492178-1490355 (Counterclockwise)

Preceding gene: 126445884

Following gene: 126447831

Centisome position: 63.42

GC content: 67.71

Gene sequence:

>1824_bases
TTGCCTGAGCGCCGGTTTTCGTGCGAATCTGCCGCCGCGGCATACGACAGACAAACACGCCGCCACGCGTCGGGCCCGCG
CGATCAGGAGACCGTATTGCCGTTCATCTCGAAAACGGGAGGAGGAGATATGGTCACGCCGCGGCATCGCCCGCTTCATG
TTGAAAATCCGTTCTATCGTCGCCTGCTGAACGCGCCCGCGTGGGTCGCGCTCGTCGCCGCGGCCGGCATCGGCTGCACG
AGCGCGACGCTCGCCCGCGCCGATTCGTCGCCGGCGCACGCGTCCACGGCCGCGGCCGTGGCGAGCGCCGCATCCGCGCC
GGGCGCCGCGTCGATTCCGCCGCCGCCGAGCCAGCTCTACGGCGATCTCTTTGTTGCGGTGCAAACCGCGCAGATCTTCG
CGGATCAGAAGACCTTCGTCGATTCGACGCCGAACGCCGATCCCGCGACGATCGTCCAGCTGTACCAGCAGCAGAAGGGC
CAGCCGGGCTTCTCGCTGAAGGCGTTCGTCGCGCAATACTTCACGCCGCCGTCGGACGAATCGGTGACGCCGCCGCCGAA
CCAGACGCTGCGCGAGCACATCGACTGGCTATGGCCGAAGCTCACGCGCACCACCACGACGGCGCCGCCGTACAGCTCGC
TGATTGCGCTGCCCAAACCGTACGTGGTGCCGGGCGGGCGCTTCCGCGAAGGCTACTACTGGGACACGTACTTCACGATG
CTCGGCTTGCAGGAGGCGGGCCGGGAAGATCTCGTCGACAACATGCTCGACAACTTCGCGTACCTGATCGACACCGTCGG
CCACGTGCCGAACGGCAACCGCAGCTATTACGTGAGCCGCTCGCAGCCGCCGTTCTTCGCGTACATGGTGACGCTCGCGG
CGAAGGCCGAGGGCAATCGCGTCTATCAGAAGTACCTGCCCGCGCTGCGCAAGGAGTACGCGTACTGGATGCAGGGCGAG
CGCACCACGCCGCGCGGCCAGGCGACGCGCAACGTCGTCGCGATGCCGGACGGCTCGGTGCTGAACCGCTACTGGGACGC
GAGCGACACGCCGCGCGACGAGTCGTATCTCGAAGACGTGAAGACCGCGCAGCAGGCGAGCGGCCGGCCGGCGGCGGAAG
TCTGGCGCGATCTGCGCGCGGCGGCGGAGAGCGGCTGGGATTTCAGCTCGCGCTGGTTCGGCGACAACCGCACGCTCGCG
ACGATCCGCACGACCGCGATCGTGCCCGTCGACTTGAACAGCCTGATGTTCAACCTCGAGACGACGATCGTGAAGGGCTG
CGCGGTGACGCGCGATTTCGCGTGCGTCGCCGAGTTCGCCGGCCGCGCGGGCAAGCGCGCGGTTGCGATCAACCGCTATC
TGTGGAACCGCAACGGCTATTACGGCGACTACGACTGGAAACTCGGCAAGCCGCGCGACAACCTGTCGGCGGCGGCGTTG
TATCCGCTGTTCGCGGGCGTCGCGTGGCCGGAGCGCGCGAAGCAGACCGCGAAGAACGTGCAGAAAGCGCTGCTCAAGCC
GGGCGGGCTCGCGACGACGACTTACGACACCGCGCAGCAGTGGGACGCACCTAACGGCTGGGCGCCGCTGCACTGGATCG
CGCTCGTCGGGCTGCGGCACTATGGCGAGAAGTCGCTCGCGGACGATATCGGCACGCGTTTTCTTGCCGACGTGAAGGGC
GTGTACGCGGCGCAGGGCAAGCTCGTCGAGAAGTACATCGTCGAAGGCACGGGCGGCGGCGGCGGCGGCGAGTATCCGCT
GCAGGACGGCTTCGGCTGGACCAACGGCGTGACGCTCAAGCTGCTCGATCTGTACGGCGGCTGA

Upstream 100 bases:

>100_bases
GGCTTCCCCGGGGGCCGCGTGCCTCGTGCGCGCCGGCGCGTGCGCGACGCGCCGCATGCCGCGGCCCACGGTCATTTGCG
CGAAGTGTGGGAAGAACCGC

Downstream 100 bases:

>100_bases
CGCGCGCGCATCGCGCCGCGCACGCGGGCGGCGCATGCCCGCCCGCGTGCGCGGCGTTGGCCGTTCGCGACGTTGCGTTA
TTGAGGCCGGGAATAAGCGT

Product: trehalase

Products: NA

Alternate protein names: Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase [H]

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MPERRFSCESAAAAYDRQTRRHASGPRDQETVLPFISKTGGGDMVTPRHRPLHVENPFYRRLLNAPAWVALVAAAGIGCT
SATLARADSSPAHASTAAAVASAASAPGAASIPPPPSQLYGDLFVAVQTAQIFADQKTFVDSTPNADPATIVQLYQQQKG
QPGFSLKAFVAQYFTPPSDESVTPPPNQTLREHIDWLWPKLTRTTTTAPPYSSLIALPKPYVVPGGRFREGYYWDTYFTM
LGLQEAGREDLVDNMLDNFAYLIDTVGHVPNGNRSYYVSRSQPPFFAYMVTLAAKAEGNRVYQKYLPALRKEYAYWMQGE
RTTPRGQATRNVVAMPDGSVLNRYWDASDTPRDESYLEDVKTAQQASGRPAAEVWRDLRAAAESGWDFSSRWFGDNRTLA
TIRTTAIVPVDLNSLMFNLETTIVKGCAVTRDFACVAEFAGRAGKRAVAINRYLWNRNGYYGDYDWKLGKPRDNLSAAAL
YPLFAGVAWPERAKQTAKNVQKALLKPGGLATTTYDTAQQWDAPNGWAPLHWIALVGLRHYGEKSLADDIGTRFLADVKG
VYAAQGKLVEKYIVEGTGGGGGGEYPLQDGFGWTNGVTLKLLDLYGG

Sequences:

>Translated_607_residues
MPERRFSCESAAAAYDRQTRRHASGPRDQETVLPFISKTGGGDMVTPRHRPLHVENPFYRRLLNAPAWVALVAAAGIGCT
SATLARADSSPAHASTAAAVASAASAPGAASIPPPPSQLYGDLFVAVQTAQIFADQKTFVDSTPNADPATIVQLYQQQKG
QPGFSLKAFVAQYFTPPSDESVTPPPNQTLREHIDWLWPKLTRTTTTAPPYSSLIALPKPYVVPGGRFREGYYWDTYFTM
LGLQEAGREDLVDNMLDNFAYLIDTVGHVPNGNRSYYVSRSQPPFFAYMVTLAAKAEGNRVYQKYLPALRKEYAYWMQGE
RTTPRGQATRNVVAMPDGSVLNRYWDASDTPRDESYLEDVKTAQQASGRPAAEVWRDLRAAAESGWDFSSRWFGDNRTLA
TIRTTAIVPVDLNSLMFNLETTIVKGCAVTRDFACVAEFAGRAGKRAVAINRYLWNRNGYYGDYDWKLGKPRDNLSAAAL
YPLFAGVAWPERAKQTAKNVQKALLKPGGLATTTYDTAQQWDAPNGWAPLHWIALVGLRHYGEKSLADDIGTRFLADVKG
VYAAQGKLVEKYIVEGTGGGGGGEYPLQDGFGWTNGVTLKLLDLYGG
>Mature_606_residues
PERRFSCESAAAAYDRQTRRHASGPRDQETVLPFISKTGGGDMVTPRHRPLHVENPFYRRLLNAPAWVALVAAAGIGCTS
ATLARADSSPAHASTAAAVASAASAPGAASIPPPPSQLYGDLFVAVQTAQIFADQKTFVDSTPNADPATIVQLYQQQKGQ
PGFSLKAFVAQYFTPPSDESVTPPPNQTLREHIDWLWPKLTRTTTTAPPYSSLIALPKPYVVPGGRFREGYYWDTYFTML
GLQEAGREDLVDNMLDNFAYLIDTVGHVPNGNRSYYVSRSQPPFFAYMVTLAAKAEGNRVYQKYLPALRKEYAYWMQGER
TTPRGQATRNVVAMPDGSVLNRYWDASDTPRDESYLEDVKTAQQASGRPAAEVWRDLRAAAESGWDFSSRWFGDNRTLAT
IRTTAIVPVDLNSLMFNLETTIVKGCAVTRDFACVAEFAGRAGKRAVAINRYLWNRNGYYGDYDWKLGKPRDNLSAAALY
PLFAGVAWPERAKQTAKNVQKALLKPGGLATTTYDTAQQWDAPNGWAPLHWIALVGLRHYGEKSLADDIGTRFLADVKGV
YAAQGKLVEKYIVEGTGGGGGGEYPLQDGFGWTNGVTLKLLDLYGG

Specific function: Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system [H]

COG id: COG1626

COG function: function code G; Neutral trehalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 37 family [H]

Homologues:

Organism=Homo sapiens, GI116284412, Length=534, Percent_Identity=33.7078651685393, Blast_Score=246, Evalue=7e-65,
Organism=Escherichia coli, GI1787447, Length=542, Percent_Identity=52.2140221402214, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1789936, Length=500, Percent_Identity=52.8, Blast_Score=509, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17542196, Length=534, Percent_Identity=31.6479400749064, Blast_Score=252, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17565078, Length=517, Percent_Identity=32.495164410058, Blast_Score=239, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI25141398, Length=546, Percent_Identity=32.2344322344322, Blast_Score=234, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI25148109, Length=530, Percent_Identity=32.0754716981132, Blast_Score=232, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI71987755, Length=429, Percent_Identity=31.2354312354312, Blast_Score=193, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320204, Length=426, Percent_Identity=30.2816901408451, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319473, Length=434, Percent_Identity=29.9539170506912, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24656661, Length=532, Percent_Identity=32.1428571428571, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI17933716, Length=532, Percent_Identity=32.1428571428571, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24656670, Length=532, Percent_Identity=32.1428571428571, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24656680, Length=532, Percent_Identity=32.1428571428571, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24656675, Length=532, Percent_Identity=32.1428571428571, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24656685, Length=480, Percent_Identity=31.875, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI22024178, Length=534, Percent_Identity=28.4644194756554, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI45551104, Length=373, Percent_Identity=30.0268096514745, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28573474, Length=298, Percent_Identity=26.8456375838926, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR001661
- InterPro:   IPR018232 [H]

Pfam domain/function: PF01204 Trehalase [H]

EC number: =3.2.1.28 [H]

Molecular weight: Translated: 66660; Mature: 66529

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS00927 TREHALASE_1 ; PS00928 TREHALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERRFSCESAAAAYDRQTRRHASGPRDQETVLPFISKTGGGDMVTPRHRPLHVENPFYR
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEECCCHHHH
RLLNAPAWVALVAAAGIGCTSATLARADSSPAHASTAAAVASAASAPGAASIPPPPSQLY
HHHCCCHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHH
GDLFVAVQTAQIFADQKTFVDSTPNADPATIVQLYQQQKGQPGFSLKAFVAQYFTPPSDE
HHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC
SVTPPPNQTLREHIDWLWPKLTRTTTTAPPYSSLIALPKPYVVPGGRFREGYYWDTYFTM
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEECCCCCCCCCEEHHHHHHH
LGLQEAGREDLVDNMLDNFAYLIDTVGHVPNGNRSYYVSRSQPPFFAYMVTLAAKAEGNR
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCH
VYQKYLPALRKEYAYWMQGERTTPRGQATRNVVAMPDGSVLNRYWDASDTPRDESYLEDV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHCCCCCCCCCHHHHHHH
KTAQQASGRPAAEVWRDLRAAAESGWDFSSRWFGDNRTLATIRTTAIVPVDLNSLMFNLE
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHH
TTIVKGCAVTRDFACVAEFAGRAGKRAVAINRYLWNRNGYYGDYDWKLGKPRDNLSAAAL
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
YPLFAGVAWPERAKQTAKNVQKALLKPGGLATTTYDTAQQWDAPNGWAPLHWIALVGLRH
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHCCCCCCCCHHHHHHHHHHHH
YGEKSLADDIGTRFLADVKGVYAAQGKLVEKYIVEGTGGGGGGEYPLQDGFGWTNGVTLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCEEE
LLDLYGG
EEEECCC
>Mature Secondary Structure 
PERRFSCESAAAAYDRQTRRHASGPRDQETVLPFISKTGGGDMVTPRHRPLHVENPFYR
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEECCCHHHH
RLLNAPAWVALVAAAGIGCTSATLARADSSPAHASTAAAVASAASAPGAASIPPPPSQLY
HHHCCCHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHH
GDLFVAVQTAQIFADQKTFVDSTPNADPATIVQLYQQQKGQPGFSLKAFVAQYFTPPSDE
HHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC
SVTPPPNQTLREHIDWLWPKLTRTTTTAPPYSSLIALPKPYVVPGGRFREGYYWDTYFTM
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEECCCCCCCCCEEHHHHHHH
LGLQEAGREDLVDNMLDNFAYLIDTVGHVPNGNRSYYVSRSQPPFFAYMVTLAAKAEGNR
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCH
VYQKYLPALRKEYAYWMQGERTTPRGQATRNVVAMPDGSVLNRYWDASDTPRDESYLEDV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHCCCCCCCCCHHHHHHH
KTAQQASGRPAAEVWRDLRAAAESGWDFSSRWFGDNRTLATIRTTAIVPVDLNSLMFNLE
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHH
TTIVKGCAVTRDFACVAEFAGRAGKRAVAINRYLWNRNGYYGDYDWKLGKPRDNLSAAAL
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
YPLFAGVAWPERAKQTAKNVQKALLKPGGLATTTYDTAQQWDAPNGWAPLHWIALVGLRH
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHCCCCCCCCHHHHHHHHHHHH
YGEKSLADDIGTRFLADVKGVYAAQGKLVEKYIVEGTGGGGGGEYPLQDGFGWTNGVTLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCEEE
LLDLYGG
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]