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The map label for this gene is deoC

Identifier: 255767838

GI number: 255767838

Start: 4051602

End: 4052273

Strand: Reverse

Name: deoC

Synonym: BSU39420

Alternate gene names: 255767838

Gene position: 4052273-4051602 (Counterclockwise)

Preceding gene: 16080994

Following gene: 255767837

Centisome position: 96.13

GC content: 46.43

Gene sequence:

>672_bases
ATGTCATTAGCCAACATAATTGATCATACAGCTTTGAAACCGCATACACAAAAAGCGGACATTCTAAAACTAATTGAAGA
AGCGAAAACATACAAATTTGCTTCAGTATGTGTCAATCCGACATGGGTGGAGCTTGCTGCAAAAGAGCTTAAGGGAACTG
GAGTCGACGTTTGTACGGTCATCGGCTTCCCGCTCGGTGCCAATACAACTGAAACAAAAGCGTTCGAAACAAAAGACGCC
ATTTCAAAAGGCGCCACTGAAGTGGATATGGTCATTAATATTGCCGCTTTAAAAGACAAGGAAGACGATGTGGTGGAAGC
TGATATCCGCGGTGTAGTGGAAGCTGTAGCCGGAAAAGCGCTTGTCAAAGTCATTATCGAAACGTGCCTTCTGACTGATG
AAGAAAAAGAACGTGCATGCCGTTTAGCGGTGTCTGCGGGAGCGGATTTCGTAAAAACATCAACAGGCTTTTCTACAGGC
GGCGCAACGAAGGAAGATATCGCCTTAATGCGCAAAACAGTAGGGCCTGATATCGGCGTGAAAGCATCTGGCGGCGTCAG
AACGAAAGAAGATGTAGACACAATGGTAGAGGCCGGAGCAAGCCGAATTGGCGCCAGCGCAGGCGTTTCTATCGTAAAAG
GAGAAAATGCATCAGGCGGAGACAACTATTAA

Upstream 100 bases:

>100_bases
TCAAACCTTTCATTGAACAAAATTTCAATTACCAATTTACATATGTTCAAAAGTCGGTTATGCTAAAAAATATCTTAACA
AAAAAGGAAGTGTGCGAAGG

Downstream 100 bases:

>100_bases
GAGCTGACGGAAGGCAGACTGCTTTCCGTTTTCTGAGGAAACAGTAATTGTAAGCGAATACAAATAAAGGAGAAACACAT
ATGAAGTATTTGATTGGGAT

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSLANIIDHTALKPHTQKADILKLIEEAKTYKFASVCVNPTWVELAAKELKGTGVDVCTVIGFPLGANTTETKAFETKDA
ISKGATEVDMVINIAALKDKEDDVVEADIRGVVEAVAGKALVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTG
GATKEDIALMRKTVGPDIGVKASGGVRTKEDVDTMVEAGASRIGASAGVSIVKGENASGGDNY

Sequences:

>Translated_223_residues
MSLANIIDHTALKPHTQKADILKLIEEAKTYKFASVCVNPTWVELAAKELKGTGVDVCTVIGFPLGANTTETKAFETKDA
ISKGATEVDMVINIAALKDKEDDVVEADIRGVVEAVAGKALVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTG
GATKEDIALMRKTVGPDIGVKASGGVRTKEDVDTMVEAGASRIGASAGVSIVKGENASGGDNY
>Mature_222_residues
SLANIIDHTALKPHTQKADILKLIEEAKTYKFASVCVNPTWVELAAKELKGTGVDVCTVIGFPLGANTTETKAFETKDAI
SKGATEVDMVINIAALKDKEDDVVEADIRGVVEAVAGKALVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTGG
ATKEDIALMRKTVGPDIGVKASGGVRTKEDVDTMVEAGASRIGASAGVSIVKGENASGGDNY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=200, Percent_Identity=33, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1790841, Length=212, Percent_Identity=33.9622641509434, Blast_Score=86, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17533015, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_BACSU (P39121)

Other databases:

- EMBL:   X82174
- EMBL:   D45912
- EMBL:   AL009126
- PIR:   A69619
- RefSeq:   NP_391821.2
- ProteinModelPortal:   P39121
- SMR:   P39121
- EnsemblBacteria:   EBBACT00000001757
- GeneID:   938608
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU39420
- NMPDR:   fig|224308.1.peg.3947
- GenoList:   BSU39420
- GeneTree:   EBGT00050000000908
- HOGENOM:   HBG636421
- PhylomeDB:   P39121
- ProtClustDB:   CLSK929138
- BioCyc:   BSUB:BSU39420-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23261; Mature: 23130

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: ACT_SITE 152-152 ACT_SITE 181-181

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLANIIDHTALKPHTQKADILKLIEEAKTYKFASVCVNPTWVELAAKELKGTGVDVCTV
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHH
IGFPLGANTTETKAFETKDAISKGATEVDMVINIAALKDKEDDVVEADIRGVVEAVAGKA
CCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHEEEHHHCCCCCHHHHHHHHHHHHHHHHHH
LVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTGGATKEDIALMRKTVGPDIGV
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
KASGGVRTKEDVDTMVEAGASRIGASAGVSIVKGENASGGDNY
CCCCCCCCHHHHHHHHHHHHHHCCHHCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
SLANIIDHTALKPHTQKADILKLIEEAKTYKFASVCVNPTWVELAAKELKGTGVDVCTV
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHH
IGFPLGANTTETKAFETKDAISKGATEVDMVINIAALKDKEDDVVEADIRGVVEAVAGKA
CCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHEEEHHHCCCCCHHHHHHHHHHHHHHHHHH
LVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTGGATKEDIALMRKTVGPDIGV
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
KASGGVRTKEDVDTMVEAGASRIGASAGVSIVKGENASGGDNY
CCCCCCCCHHHHHHHHHHHHHHCCHHCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550462; 8867804; 9384377