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The map label for this gene is katE

Identifier: 255767825

GI number: 255767825

Start: 4008143

End: 4010203

Strand: Reverse

Name: katE

Synonym: BSU39050

Alternate gene names: 255767825

Gene position: 4010203-4008143 (Counterclockwise)

Preceding gene: 16080958

Following gene: 255767824

Centisome position: 95.13

GC content: 49.34

Gene sequence:

>2061_bases
ATGAGTGATGACCAAAACAAACGTGTAAATGAACACTCAAAGGACGAGCAGCTTGAGCAGTACAGGACCGATAACAGCGG
GAAGAAAATGACGACAAACCAAGGCTTGCGAGTGTCAGAGGATGAGCACTCGTTAAAAGCCGGGGTTCGCGGCCCGACGC
TGATGGAGGATTTTCATTTCCGGGAGAAAATGACGCACTTTGACCATGAGAGGATTCCGGAGCGCGTTGTGCATGCGCGC
GGATTTGGCGTGCATGGCTTTTTTCAGGTTTACGAACCAATGACGGAATACACACGGGCCAAATTTCTTCAGGACCCTTC
GGTGAAGACACCGGTATTTGTCCGTTTTTCTACGGTTGCGGGTTCTAAAGGCTCCGCAGACACGGTGCGGGATGCCAGAG
GCTTTGCGACAAAATTTTATACTGAAGAAGGAAACTATGACCTTGTGGGAAATAACATTCCGGTGTTTTTCATTCAGGAC
GCAATCAAATTTCCGGATTTGGTTCACGCGTTTAAGCCTGAGCCACACAATGAAATGCCTCAGGCTGCGACTGCTCACGA
TACATTTTGGGATTTTGTCGCCAATAACCCTGAGTCTGCCCACATGGTGATGTGGACGATGTCTGACAGAGGCATCCCGC
GCAGCTACAGAATGATGGAAGGCTTCGGCGTTCACACGTTCCGTTTTGTCAATGAACAAGGAAAGGCACGTTTCGTGAAA
TTTCACTGGAAGCCGGTGCTCGGCGTGCATTCTCTCGTATGGGATGAAGCGCAAAAAATTGCCGGGAAAGATCCAGATTT
CCACCGCCGTGACCTGTGGGAAACAATTGAAAACGGCGGCAAGGTTGAATACGAGCTCGGCGTGCAGATGATTGATGAGG
AAGATGAATTCAAGTTTGATTTTGATATTCTTGACCCAACTAAGCTGTGGCCGGAAGAGCTTGTGCCGGTGAAGATCATT
GGAAAAATGACGCTGAACCGCAATCAGGATAATGTGTTTGCGGAAACAGAACAAGTCGCATTCCACCCGGGAAATGTCGT
GCCGGGCATCGATTTTACCAATGACCCGCTATTGCAGGGGCGGCTTTTCTCTTATACGGATACACAGCTCATCCGTCTTG
GCGGCCCGAACTTCCATGAGATTCCGATTAACCGGCCGGTCTGTCCATTCCATAACAACCAATACGACGGCTATCACCGG
ATGACGATCAATAAGGGACCTGTCGCTTATCATAAAAACTCACTGCAAAACAATGATCCGTCGCCTGCGACAGCTGAAGA
AGGCGGCTACGTCCACTATCAGGAAAAAGTCGAGGGCAAAAAAATCCGCCAGCGAAGCGACAGCTTCAACGATTATTACT
CACAGGCGAAGCTTTTCTGGAACAGCATGTCTCCTGTGGAGAAACAGCACATCATTTCTGCTTTCTGCTTCGAGGTCGGG
AAGGTCAAAAGCAAAGACGTACAGCGGCAGGTCGTTGATGTCTTCAGCAATGTCGATGCAGATTTAGCAGAAGAAATCGC
CAAAGGAGTAGGCGTGGCGGCGCCCGCGAAGCGTAAAGCATCTAAAGAAATTCTTACTTCGCCTGCGTTAAGCCAAGCCC
GTACAGTGAAAACCGCGTCAACAAGAAAAGTCGCTGTACTCGCCGGAAACGGATTTCATGAAAAAGAGCTGCAAACAGTA
CTGGAAGCCTTAAAGCAAGAAGGAATCACAGTGGATATCATCAGTCAAAATCTGGGGTATATGACAAGCGGCAGCGGACA
GCAGCTTGAGGCCAGCGGCACGTTCCTGACGGTTGATTCTGTTCTGTATGATGCCGTCTATGCCGCAGGAGGACTGGAGT
TAAAAGACAACAAACAAGCGATGGCGTTTATCAGAGAAGCTTACAATCACTACAAGGCGATCGGTGCGGCAAATGAAGGA
ATTGACCTTCTTCAATCCTCTGTCGGGACAACAGAGGGGCTAGGCATCGTAACGGCTAAAGATGAACCTGACTACACCGC
TTTCAGCAAGGCATTTATCGATGCGGTTGCTGCTCATCGCCATTGGGATAGACGAATTTGA

Upstream 100 bases:

>100_bases
TGTAGACCAAAAATCCTAATGAGCGGATTAGCAGTTTATATGAAGAACGCCACGGGTAAATGTGCTGTAGAATGTTTCGT
TTTAAAAAGGGGGAGCAGAC

Downstream 100 bases:

>100_bases
TCGGCTCCTGTATCTTTAAGGAAGATACTTTTCATAAGGAGCATGACAAATGAACGAAAAACAGCTCACTGAAGCTTACG
AACGCGATGAAAATATGATG

Product: catalase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MSDDQNKRVNEHSKDEQLEQYRTDNSGKKMTTNQGLRVSEDEHSLKAGVRGPTLMEDFHFREKMTHFDHERIPERVVHAR
GFGVHGFFQVYEPMTEYTRAKFLQDPSVKTPVFVRFSTVAGSKGSADTVRDARGFATKFYTEEGNYDLVGNNIPVFFIQD
AIKFPDLVHAFKPEPHNEMPQAATAHDTFWDFVANNPESAHMVMWTMSDRGIPRSYRMMEGFGVHTFRFVNEQGKARFVK
FHWKPVLGVHSLVWDEAQKIAGKDPDFHRRDLWETIENGGKVEYELGVQMIDEEDEFKFDFDILDPTKLWPEELVPVKII
GKMTLNRNQDNVFAETEQVAFHPGNVVPGIDFTNDPLLQGRLFSYTDTQLIRLGGPNFHEIPINRPVCPFHNNQYDGYHR
MTINKGPVAYHKNSLQNNDPSPATAEEGGYVHYQEKVEGKKIRQRSDSFNDYYSQAKLFWNSMSPVEKQHIISAFCFEVG
KVKSKDVQRQVVDVFSNVDADLAEEIAKGVGVAAPAKRKASKEILTSPALSQARTVKTASTRKVAVLAGNGFHEKELQTV
LEALKQEGITVDIISQNLGYMTSGSGQQLEASGTFLTVDSVLYDAVYAAGGLELKDNKQAMAFIREAYNHYKAIGAANEG
IDLLQSSVGTTEGLGIVTAKDEPDYTAFSKAFIDAVAAHRHWDRRI

Sequences:

>Translated_686_residues
MSDDQNKRVNEHSKDEQLEQYRTDNSGKKMTTNQGLRVSEDEHSLKAGVRGPTLMEDFHFREKMTHFDHERIPERVVHAR
GFGVHGFFQVYEPMTEYTRAKFLQDPSVKTPVFVRFSTVAGSKGSADTVRDARGFATKFYTEEGNYDLVGNNIPVFFIQD
AIKFPDLVHAFKPEPHNEMPQAATAHDTFWDFVANNPESAHMVMWTMSDRGIPRSYRMMEGFGVHTFRFVNEQGKARFVK
FHWKPVLGVHSLVWDEAQKIAGKDPDFHRRDLWETIENGGKVEYELGVQMIDEEDEFKFDFDILDPTKLWPEELVPVKII
GKMTLNRNQDNVFAETEQVAFHPGNVVPGIDFTNDPLLQGRLFSYTDTQLIRLGGPNFHEIPINRPVCPFHNNQYDGYHR
MTINKGPVAYHKNSLQNNDPSPATAEEGGYVHYQEKVEGKKIRQRSDSFNDYYSQAKLFWNSMSPVEKQHIISAFCFEVG
KVKSKDVQRQVVDVFSNVDADLAEEIAKGVGVAAPAKRKASKEILTSPALSQARTVKTASTRKVAVLAGNGFHEKELQTV
LEALKQEGITVDIISQNLGYMTSGSGQQLEASGTFLTVDSVLYDAVYAAGGLELKDNKQAMAFIREAYNHYKAIGAANEG
IDLLQSSVGTTEGLGIVTAKDEPDYTAFSKAFIDAVAAHRHWDRRI
>Mature_685_residues
SDDQNKRVNEHSKDEQLEQYRTDNSGKKMTTNQGLRVSEDEHSLKAGVRGPTLMEDFHFREKMTHFDHERIPERVVHARG
FGVHGFFQVYEPMTEYTRAKFLQDPSVKTPVFVRFSTVAGSKGSADTVRDARGFATKFYTEEGNYDLVGNNIPVFFIQDA
IKFPDLVHAFKPEPHNEMPQAATAHDTFWDFVANNPESAHMVMWTMSDRGIPRSYRMMEGFGVHTFRFVNEQGKARFVKF
HWKPVLGVHSLVWDEAQKIAGKDPDFHRRDLWETIENGGKVEYELGVQMIDEEDEFKFDFDILDPTKLWPEELVPVKIIG
KMTLNRNQDNVFAETEQVAFHPGNVVPGIDFTNDPLLQGRLFSYTDTQLIRLGGPNFHEIPINRPVCPFHNNQYDGYHRM
TINKGPVAYHKNSLQNNDPSPATAEEGGYVHYQEKVEGKKIRQRSDSFNDYYSQAKLFWNSMSPVEKQHIISAFCFEVGK
VKSKDVQRQVVDVFSNVDADLAEEIAKGVGVAAPAKRKASKEILTSPALSQARTVKTASTRKVAVLAGNGFHEKELQTVL
EALKQEGITVDIISQNLGYMTSGSGQQLEASGTFLTVDSVLYDAVYAAGGLELKDNKQAMAFIREAYNHYKAIGAANEGI
DLLQSSVGTTEGLGIVTAKDEPDYTAFSKAFIDAVAAHRHWDRRI

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily

Homologues:

Organism=Homo sapiens, GI4557014, Length=502, Percent_Identity=39.6414342629482, Blast_Score=354, Evalue=2e-97,
Organism=Escherichia coli, GI48994891, Length=696, Percent_Identity=53.448275862069, Blast_Score=755, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25151141, Length=503, Percent_Identity=41.351888667992, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI25147792, Length=503, Percent_Identity=41.351888667992, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71998444, Length=498, Percent_Identity=40.5622489959839, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320462, Length=499, Percent_Identity=36.87374749499, Blast_Score=315, Evalue=1e-86,
Organism=Saccharomyces cerevisiae, GI6321525, Length=509, Percent_Identity=35.7563850687623, Blast_Score=304, Evalue=3e-83,
Organism=Drosophila melanogaster, GI17981717, Length=509, Percent_Identity=38.8998035363458, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI19920968, Length=517, Percent_Identity=34.816247582205, Blast_Score=325, Evalue=5e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CATE_BACSU (P42234)

Other databases:

- EMBL:   D83026
- EMBL:   AL009126
- EMBL:   X85182
- PIR:   D69647
- RefSeq:   NP_391784.2
- ProteinModelPortal:   P42234
- SMR:   P42234
- PeroxiBase:   4059
- EnsemblBacteria:   EBBACT00000003133
- GeneID:   937481
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU39050
- NMPDR:   fig|224308.1.peg.3910
- GenoList:   BSU39050
- GeneTree:   EBGT00050000002743
- HOGENOM:   HBG339355
- PhylomeDB:   P42234
- ProtClustDB:   CLSK2301490
- BioCyc:   BSUB:BSU39050-MONOMER
- BRENDA:   1.11.1.6
- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- InterPro:   IPR002818
- Gene3D:   G3DSA:2.40.180.10
- PANTHER:   PTHR11465
- PRINTS:   PR00067

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; PF01965 DJ-1_PfpI; SSF56634 Catalase_N

EC number: =1.11.1.6

Molecular weight: Translated: 77481; Mature: 77350

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00437 CATALASE_1; PS00438 CATALASE_2; PS51402 CATALASE_3

Important sites: ACT_SITE 78-78 ACT_SITE 151-151

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDQNKRVNEHSKDEQLEQYRTDNSGKKMTTNQGLRVSEDEHSLKAGVRGPTLMEDFHF
CCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCEECCCHHHHHCCCCCCHHHHHHHH
REKMTHFDHERIPERVVHARGFGVHGFFQVYEPMTEYTRAKFLQDPSVKTPVFVRFSTVA
HHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEC
GSKGSADTVRDARGFATKFYTEEGNYDLVGNNIPVFFIQDAIKFPDLVHAFKPEPHNEMP
CCCCCCHHHHHHHHCEEEEEECCCCEEEECCCCCEEEECCHHCCHHHHHHCCCCCCCCCC
QAATAHDTFWDFVANNPESAHMVMWTMSDRGIPRSYRMMEGFGVHTFRFVNEQGKARFVK
CCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCEEEEE
FHWKPVLGVHSLVWDEAQKIAGKDPDFHRRDLWETIENGGKVEYELGVQMIDEEDEFKFD
EECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCEEECCCCCEEEE
FDILDPTKLWPEELVPVKIIGKMTLNRNQDNVFAETEQVAFHPGNVVPGIDFTNDPLLQG
EEECCCCCCCHHHCCCEEEEEEEEECCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCC
RLFSYTDTQLIRLGGPNFHEIPINRPVCPFHNNQYDGYHRMTINKGPVAYHKNSLQNNDP
EEECCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEEEECCCCCEECCCCCCCCCC
SPATAEEGGYVHYQEKVEGKKIRQRSDSFNDYYSQAKLFWNSMSPVEKQHIISAFCFEVG
CCCCCCCCCEEEEHHHHCHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
KVKSKDVQRQVVDVFSNVDADLAEEIAKGVGVAAPAKRKASKEILTSPALSQARTVKTAS
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHEECCC
TRKVAVLAGNGFHEKELQTVLEALKQEGITVDIISQNLGYMTSGSGQQLEASGTFLTVDS
CCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCCEEECCCCEEEHHH
VLYDAVYAAGGLELKDNKQAMAFIREAYNHYKAIGAANEGIDLLQSSVGTTEGLGIVTAK
HHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEC
DEPDYTAFSKAFIDAVAAHRHWDRRI
CCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDDQNKRVNEHSKDEQLEQYRTDNSGKKMTTNQGLRVSEDEHSLKAGVRGPTLMEDFHF
CCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCEECCCHHHHHCCCCCCHHHHHHHH
REKMTHFDHERIPERVVHARGFGVHGFFQVYEPMTEYTRAKFLQDPSVKTPVFVRFSTVA
HHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEC
GSKGSADTVRDARGFATKFYTEEGNYDLVGNNIPVFFIQDAIKFPDLVHAFKPEPHNEMP
CCCCCCHHHHHHHHCEEEEEECCCCEEEECCCCCEEEECCHHCCHHHHHHCCCCCCCCCC
QAATAHDTFWDFVANNPESAHMVMWTMSDRGIPRSYRMMEGFGVHTFRFVNEQGKARFVK
CCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCEEEEE
FHWKPVLGVHSLVWDEAQKIAGKDPDFHRRDLWETIENGGKVEYELGVQMIDEEDEFKFD
EECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCEEECCCCCEEEE
FDILDPTKLWPEELVPVKIIGKMTLNRNQDNVFAETEQVAFHPGNVVPGIDFTNDPLLQG
EEECCCCCCCHHHCCCEEEEEEEEECCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCC
RLFSYTDTQLIRLGGPNFHEIPINRPVCPFHNNQYDGYHRMTINKGPVAYHKNSLQNNDP
EEECCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEEEECCCCCEECCCCCCCCCC
SPATAEEGGYVHYQEKVEGKKIRQRSDSFNDYYSQAKLFWNSMSPVEKQHIISAFCFEVG
CCCCCCCCCEEEEHHHHCHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
KVKSKDVQRQVVDVFSNVDADLAEEIAKGVGVAAPAKRKASKEILTSPALSQARTVKTAS
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHEECCC
TRKVAVLAGNGFHEKELQTVLEALKQEGITVDIISQNLGYMTSGSGQQLEASGTFLTVDS
CCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCCEEECCCCEEEHHH
VLYDAVYAAGGLELKDNKQAMAFIREAYNHYKAIGAANEGIDLLQSSVGTTEGLGIVTAK
HHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEEC
DEPDYTAFSKAFIDAVAAHRHWDRRI
CCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377