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The map label for this gene is cymR

Identifier: 255767629

GI number: 255767629

Start: 2811717

End: 2812133

Strand: Reverse

Name: cymR

Synonym: BSU27520

Alternate gene names: 255767629

Gene position: 2812133-2811717 (Counterclockwise)

Preceding gene: 255767630

Following gene: 50812274

Centisome position: 66.71

GC content: 47.0

Gene sequence:

>417_bases
TTGAAAATATCAACTAAGGGAAGATACGGGCTCACCATTATGATCGAGCTTGCAAAAAAGCACGGTGAAGGCCCGACTTC
ATTAAAAAGCATCGCACAGACGAATAATTTGTCCGAGCATTATTTGGAGCAGCTGGTATCGCCGCTCAGAAATGCCGGTT
TAGTGAAAAGCATCAGAGGCGCATATGGCGGATATGTATTAGGCAGTGAGCCGGATGCCATTACTGCGGGAGATATTATC
CGTGTGCTTGAGGGGCCGATCAGCCCTGTTGAAGTGCTGGAAGATGAGGAGCCTGCCAAGCGTGAGCTCTGGATTCGCAT
CCGGGATGCTGTAAAAGAGGTTTTAGACAGTACAACATTAGAGGATCTTGCCAGCTATACAGACGGAGAGCAAGAAGCTT
ATATGTTCTATATTTAG

Upstream 100 bases:

>100_bases
TGTTATAATAACAGTTGGTCTATAAGATAATAAACGGACGAAACATATAGAAATTACCATTATAAATGTGGAAAATCATG
AAATAACAGAGGTGTTCATG

Downstream 100 bases:

>100_bases
ATCAGAGGTGTAAACATAATGGAACGGATTTATTTAGATCATGCCGCAACGTCTCCGATGGATGAGCGCGTGCTGGAACA
AATGATACCGCACTTCTCCG

Product: transcriptional regulator of cysteine biosynthesis

Products: NA

Alternate protein names: Cysteine metabolism repressor

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKISTKGRYGLTIMIELAKKHGEGPTSLKSIAQTNNLSEHYLEQLVSPLRNAGLVKSIRGAYGGYVLGSEPDAITAGDII
RVLEGPISPVEVLEDEEPAKRELWIRIRDAVKEVLDSTTLEDLASYTDGEQEAYMFYI

Sequences:

>Translated_138_residues
MKISTKGRYGLTIMIELAKKHGEGPTSLKSIAQTNNLSEHYLEQLVSPLRNAGLVKSIRGAYGGYVLGSEPDAITAGDII
RVLEGPISPVEVLEDEEPAKRELWIRIRDAVKEVLDSTTLEDLASYTDGEQEAYMFYI
>Mature_138_residues
MKISTKGRYGLTIMIELAKKHGEGPTSLKSIAQTNNLSEHYLEQLVSPLRNAGLVKSIRGAYGGYVLGSEPDAITAGDII
RVLEGPISPVEVLEDEEPAKRELWIRIRDAVKEVLDSTTLEDLASYTDGEQEAYMFYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788880, Length=131, Percent_Identity=32.0610687022901, Blast_Score=76, Evalue=1e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): CYMR_BACSU (O34527)

Other databases:

- EMBL:   AL009126
- PIR:   B69982
- RefSeq:   NP_390630.2
- ProteinModelPortal:   O34527
- SMR:   O34527
- EnsemblBacteria:   EBBACT00000003818
- GeneID:   936456
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU27520
- NMPDR:   fig|224308.1.peg.2755
- GenoList:   BSU27520
- GeneTree:   EBGT00070000032118
- HOGENOM:   HBG725923
- ProtClustDB:   CLSK2463167
- BioCyc:   BSUB:BSU27520-MONOMER
- GO:   GO:0006350
- InterPro:   IPR000944
- TIGRFAMs:   TIGR00738

Pfam domain/function: PF02082 Rrf2

EC number: NA

Molecular weight: Translated: 15256; Mature: 15256

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS01332 HTH_RRF2_1; PS51197 HTH_RRF2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTKGRYGLTIMIELAKKHGEGPTSLKSIAQTNNLSEHYLEQLVSPLRNAGLVKSIRG
CCCCCCCCCCHHHHEEEHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHH
AYGGYVLGSEPDAITAGDIIRVLEGPISPVEVLEDEEPAKRELWIRIRDAVKEVLDSTTL
HHCCEEECCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCH
EDLASYTDGEQEAYMFYI
HHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MKISTKGRYGLTIMIELAKKHGEGPTSLKSIAQTNNLSEHYLEQLVSPLRNAGLVKSIRG
CCCCCCCCCCHHHHEEEHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHH
AYGGYVLGSEPDAITAGDIIRVLEGPISPVEVLEDEEPAKRELWIRIRDAVKEVLDSTTL
HHCCEEECCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCH
EDLASYTDGEQEAYMFYI
HHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377