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The map label for this gene is dsdA

Identifier: 255767515

GI number: 255767515

Start: 2469580

End: 2470926

Strand: Reverse

Name: dsdA

Synonym: BSU23770

Alternate gene names: 255767515

Gene position: 2470926-2469580 (Counterclockwise)

Preceding gene: 16079435

Following gene: 50812263

Centisome position: 58.61

GC content: 47.74

Gene sequence:

>1347_bases
ATGTCAGTTCATTCAGAAGTCCTTCATGCTCTGCTTAAAGATCCGTTTATTCAGAAACTGATTGATGCAGAGCCTGTATT
CTGGGCAAATTCAGGCAAGAAAGAGGGGCCATTACCCCGTGCAGATGAGTGGGCAACCGAGATAGCGGAAGCGGAAAAAA
GAATGCAGCGGTTTGCACCTTACATTGCCGAGGTGTTTCCTGAGACGAAAGGCGCTAAAGGAATCATCGAGTCTCCGCTT
TTTGAGGTGCAGCATATGAAGGGAAAGCTGGAAGCGGCATATCAGCAGCCATTTCCCGGAAGATGGCTTTTAAAGTGCGA
CCATGAGCTTCCGATTTCAGGATCGATTAAAGCGAGGGGCGGGATTTATGAAGTGTTAAAGTATGCTGAAAATCTCGCGC
TTCAAGAAGGAATGCTTCAGGAAACCGATGATTACCGCATCTTACAGGAAGAGCGGTTTACCGGGTTTTTCTCCCGCTAT
TCGATTGCTGTCGGTTCGACAGGAAATCTAGGTTTAAGCATCGGCATCATCGGCGCGGCACTCGGGTTTCGCGTGACAGT
GCATATGTCCGCCGATGCTAAGCAGTGGAAAAAGGATCTCCTCCGCCAAAAGGGAGTCACTGTTATGGAGTACGAAACAG
ATTACAGTGAAGCGGTGAACGAAGGGAGACGGCAGGCGGAACAAGATCCATTCTGTTATTTTATTGATGATGAACATTCT
CGTCAGCTGTTCTTAGGATATGCTGTTGCTGCAAGCCGATTAAAAACACAGCTTGACTGTATGAATATAAAGCCAAGTCT
TGAGACGCCCTTGTTTGTGTATCTGCCGTGCGGAGTCGGCGGAGGACCGGGCGGTGTAGCATTTGGGCTGAAGCTTTTAT
ACGGAGATGATGTTCATGTGTTTTTCGCAGAACCAACTCATTCACCTTGTATGCTGTTAGGGCTTTATTCAGGACTTCAC
GAGAAGATCTCCGTCCAGGATATCGGCCTGGATAATCAGACGGCTGCTGACGGACTTGCCGTAGGGAGGCCGTCAGGATT
TGTCGGCAAGCTGATTGAACCGCTTCTGAGCGGCTGTTATACGGTAGAGGACAATACGCTTTATACTTTGCTTCATATGC
TGGCTGTATCTGAAGATAAATATTTAGAGCCCTCTGCTCTTGCTGGCATGTTCGGGCCGGTTCAGCTTTTTTCGACAGAA
GAGGGAAGGCGCTATGCTCAGAAATATAAGATGGAACATGCCGTACATGTCGTCTGGGGAACGGGAGGAAGCATGGTTCC
AAAAGATGAAATGGCTGCGTATAACCGAATCGGTGCTGATTTGCTAAAAAAACGAAATGAAAAATAA

Upstream 100 bases:

>100_bases
AGGACGCGCGCTCATGAAAAAATAATGATAGAACTGCCTGTGGTGGAGTGGCTTGTTTCTCACGGGGCAGTTTTTGATAG
TGGAAGGGAGAGATTGTTGA

Downstream 100 bases:

>100_bases
GCAGACAGTGAAAAGGTTTTCCGTTACAATCTTTGTAAGGGTTTTAACCTACAGAGAGTCAGGTGTAAACAGTGAAAAAT
AAAGAACTTAACCTACATAC

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MSVHSEVLHALLKDPFIQKLIDAEPVFWANSGKKEGPLPRADEWATEIAEAEKRMQRFAPYIAEVFPETKGAKGIIESPL
FEVQHMKGKLEAAYQQPFPGRWLLKCDHELPISGSIKARGGIYEVLKYAENLALQEGMLQETDDYRILQEERFTGFFSRY
SIAVGSTGNLGLSIGIIGAALGFRVTVHMSADAKQWKKDLLRQKGVTVMEYETDYSEAVNEGRRQAEQDPFCYFIDDEHS
RQLFLGYAVAASRLKTQLDCMNIKPSLETPLFVYLPCGVGGGPGGVAFGLKLLYGDDVHVFFAEPTHSPCMLLGLYSGLH
EKISVQDIGLDNQTAADGLAVGRPSGFVGKLIEPLLSGCYTVEDNTLYTLLHMLAVSEDKYLEPSALAGMFGPVQLFSTE
EGRRYAQKYKMEHAVHVVWGTGGSMVPKDEMAAYNRIGADLLKKRNEK

Sequences:

>Translated_448_residues
MSVHSEVLHALLKDPFIQKLIDAEPVFWANSGKKEGPLPRADEWATEIAEAEKRMQRFAPYIAEVFPETKGAKGIIESPL
FEVQHMKGKLEAAYQQPFPGRWLLKCDHELPISGSIKARGGIYEVLKYAENLALQEGMLQETDDYRILQEERFTGFFSRY
SIAVGSTGNLGLSIGIIGAALGFRVTVHMSADAKQWKKDLLRQKGVTVMEYETDYSEAVNEGRRQAEQDPFCYFIDDEHS
RQLFLGYAVAASRLKTQLDCMNIKPSLETPLFVYLPCGVGGGPGGVAFGLKLLYGDDVHVFFAEPTHSPCMLLGLYSGLH
EKISVQDIGLDNQTAADGLAVGRPSGFVGKLIEPLLSGCYTVEDNTLYTLLHMLAVSEDKYLEPSALAGMFGPVQLFSTE
EGRRYAQKYKMEHAVHVVWGTGGSMVPKDEMAAYNRIGADLLKKRNEK
>Mature_447_residues
SVHSEVLHALLKDPFIQKLIDAEPVFWANSGKKEGPLPRADEWATEIAEAEKRMQRFAPYIAEVFPETKGAKGIIESPLF
EVQHMKGKLEAAYQQPFPGRWLLKCDHELPISGSIKARGGIYEVLKYAENLALQEGMLQETDDYRILQEERFTGFFSRYS
IAVGSTGNLGLSIGIIGAALGFRVTVHMSADAKQWKKDLLRQKGVTVMEYETDYSEAVNEGRRQAEQDPFCYFIDDEHSR
QLFLGYAVAASRLKTQLDCMNIKPSLETPLFVYLPCGVGGGPGGVAFGLKLLYGDDVHVFFAEPTHSPCMLLGLYSGLHE
KISVQDIGLDNQTAADGLAVGRPSGFVGKLIEPLLSGCYTVEDNTLYTLLHMLAVSEDKYLEPSALAGMFGPVQLFSTEE
GRRYAQKYKMEHAVHVVWGTGGSMVPKDEMAAYNRIGADLLKKRNEK

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=428, Percent_Identity=57.7102803738318, Blast_Score=458, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_BACSU (P54555)

Other databases:

- EMBL:   D84432
- EMBL:   AL009126
- PIR:   B69965
- RefSeq:   NP_390258.2
- ProteinModelPortal:   P54555
- EnsemblBacteria:   EBBACT00000001084
- GeneID:   938700
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU23770
- NMPDR:   fig|224308.1.peg.2382
- GenoList:   BSU23770
- GeneTree:   EBGT00050000001628
- HOGENOM:   HBG288722
- PhylomeDB:   P54555
- ProtClustDB:   PRK02991
- BioCyc:   BSUB:BSU23770-MONOMER
- BRENDA:   4.3.1.18
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 49733; Mature: 49601

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHSEVLHALLKDPFIQKLIDAEPVFWANSGKKEGPLPRADEWATEIAEAEKRMQRFAP
CCHHHHHHHHHHHCHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YIAEVFPETKGAKGIIESPLFEVQHMKGKLEAAYQQPFPGRWLLKCDHELPISGSIKARG
HHHHHCCCCCCCCCCHHCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
GIYEVLKYAENLALQEGMLQETDDYRILQEERFTGFFSRYSIAVGSTGNLGLSIGIIGAA
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCEEHHHHHHH
LGFRVTVHMSADAKQWKKDLLRQKGVTVMEYETDYSEAVNEGRRQAEQDPFCYFIDDEHS
HCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCC
RQLFLGYAVAASRLKTQLDCMNIKPSLETPLFVYLPCGVGGGPGGVAFGLKLLYGDDVHV
CEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHEEEEEECCCEEE
FFAEPTHSPCMLLGLYSGLHEKISVQDIGLDNQTAADGLAVGRPSGFVGKLIEPLLSGCY
EEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCE
TVEDNTLYTLLHMLAVSEDKYLEPSALAGMFGPVQLFSTEEGRRYAQKYKMEHAVHVVWG
ECCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCHHHHHHHHHHHHHHEEEEEEC
TGGSMVPKDEMAAYNRIGADLLKKRNEK
CCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVHSEVLHALLKDPFIQKLIDAEPVFWANSGKKEGPLPRADEWATEIAEAEKRMQRFAP
CHHHHHHHHHHHCHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YIAEVFPETKGAKGIIESPLFEVQHMKGKLEAAYQQPFPGRWLLKCDHELPISGSIKARG
HHHHHCCCCCCCCCCHHCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCC
GIYEVLKYAENLALQEGMLQETDDYRILQEERFTGFFSRYSIAVGSTGNLGLSIGIIGAA
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCEEHHHHHHH
LGFRVTVHMSADAKQWKKDLLRQKGVTVMEYETDYSEAVNEGRRQAEQDPFCYFIDDEHS
HCEEEEEEECCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCC
RQLFLGYAVAASRLKTQLDCMNIKPSLETPLFVYLPCGVGGGPGGVAFGLKLLYGDDVHV
CEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHEEEEEECCCEEE
FFAEPTHSPCMLLGLYSGLHEKISVQDIGLDNQTAADGLAVGRPSGFVGKLIEPLLSGCY
EEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCE
TVEDNTLYTLLHMLAVSEDKYLEPSALAGMFGPVQLFSTEEGRRYAQKYKMEHAVHVVWG
ECCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCHHHHHHHHHHHHHHEEEEEEC
TGGSMVPKDEMAAYNRIGADLLKKRNEK
CCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377