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The map label for this gene is ykuV

Identifier: 255767334

GI number: 255767334

Start: 1492875

End: 1493321

Strand: Direct

Name: ykuV

Synonym: BSU14230

Alternate gene names: 255767334

Gene position: 1492875-1493321 (Clockwise)

Preceding gene: 16078486

Following gene: 16078488

Centisome position: 35.41

GC content: 44.07

Gene sequence:

>447_bases
ATGAAATTACGTCAGCCCATGCCGGAATTGACGGGAGAAAAAGCTTGGTTAAATGGTGAAGTGACGAGAGAGCAATTGAT
TGGGGAAAAGCCGACGCTTATTCATTTCTGGTCCATCAGCTGCCACTTGTGCAAAGAAGCGATGCCGCAAGTGAATGAAT
TTCGTGATAAATATCAAGATCAGCTGAATGTTGTAGCTGTACACATGCCCCGTTCCGAAGATGATCTTGACCCTGGTAAA
ATTAAAGAAACAGCTGCTGAACACGATATCACTCAGCCGATTTTTGTTGACAGTGACCATGCTTTAACCGATGCATTTGA
AAATGAATATGTACCTGCATATTATGTGTTTGATAAAACAGGACAGCTCCGTCACTTCCAAGCCGGCGGGAGCGGTATGA
AAATGCTTGAAAAACGTGTGAACCGCGTTCTGGCTGAAACGGAATAG

Upstream 100 bases:

>100_bases
ACTGGAAACCAGGCCAAAAAACACTTTAATTCTTTCCAAGAACGAAAAGCGGTCTAGCATATTCGTTAGGCCTCTCTTTT
AAAATAGGAGGGAAAAAGCA

Downstream 100 bases:

>100_bases
GTATCTGACTAAATAGTATTTCCTAAAAACCTGACCTCATCAGGTTTTTTATTTGTGCAAAAAGCAATGGAAGAAGAGTA
AGAAGCTTATTTTTCCAAAT

Product: thiol-disulfide isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKLRQPMPELTGEKAWLNGEVTREQLIGEKPTLIHFWSISCHLCKEAMPQVNEFRDKYQDQLNVVAVHMPRSEDDLDPGK
IKETAAEHDITQPIFVDSDHALTDAFENEYVPAYYVFDKTGQLRHFQAGGSGMKMLEKRVNRVLAETE

Sequences:

>Translated_148_residues
MKLRQPMPELTGEKAWLNGEVTREQLIGEKPTLIHFWSISCHLCKEAMPQVNEFRDKYQDQLNVVAVHMPRSEDDLDPGK
IKETAAEHDITQPIFVDSDHALTDAFENEYVPAYYVFDKTGQLRHFQAGGSGMKMLEKRVNRVLAETE
>Mature_148_residues
MKLRQPMPELTGEKAWLNGEVTREQLIGEKPTLIHFWSISCHLCKEAMPQVNEFRDKYQDQLNVVAVHMPRSEDDLDPGK
IKETAAEHDITQPIFVDSDHALTDAFENEYVPAYYVFDKTGQLRHFQAGGSGMKMLEKRVNRVLAETE

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YKUV_BACSU (O31699)

Other databases:

- EMBL:   AJ222587
- EMBL:   AL009126
- PIR:   C69867
- RefSeq:   NP_389306.2
- PDB:   2B5X
- PDB:   2B5Y
- PDBsum:   2B5X
- PDBsum:   2B5Y
- ProteinModelPortal:   O31699
- SMR:   O31699
- EnsemblBacteria:   EBBACT00000003308
- GeneID:   938804
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14230
- NMPDR:   fig|224308.1.peg.1425
- GenoList:   BSU14230
- GeneTree:   EBGT00050000000763
- HOGENOM:   HBG493509
- ProtClustDB:   CLSK873384
- BioCyc:   BSUB:BSU14230-MONOMER
- GO:   GO:0005737
- GO:   GO:0006810
- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF00578 AhpC-TSA; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 17017; Mature: 17017

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRQPMPELTGEKAWLNGEVTREQLIGEKPTLIHFWSISCHLCKEAMPQVNEFRDKYQD
CCCCCCCCHHCCCCEECCCCHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
QLNVVAVHMPRSEDDLDPGKIKETAAEHDITQPIFVDSDHALTDAFENEYVPAYYVFDKT
CEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCHHHHHHCCCCCCEEEEECCC
GQLRHFQAGGSGMKMLEKRVNRVLAETE
CCEEEEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLRQPMPELTGEKAWLNGEVTREQLIGEKPTLIHFWSISCHLCKEAMPQVNEFRDKYQD
CCCCCCCCHHCCCCEECCCCHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
QLNVVAVHMPRSEDDLDPGKIKETAAEHDITQPIFVDSDHALTDAFENEYVPAYYVFDKT
CEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCHHHHHHCCCCCCEEEEECCC
GQLRHFQAGGSGMKMLEKRVNRVLAETE
CCEEEEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377