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The map label for this gene is patA

Identifier: 255767325

GI number: 255767325

Start: 1471857

End: 1473038

Strand: Reverse

Name: patA

Synonym: BSU14000

Alternate gene names: 255767325

Gene position: 1473038-1471857 (Counterclockwise)

Preceding gene: 255767326

Following gene: 255767324

Centisome position: 34.94

GC content: 43.32

Gene sequence:

>1182_bases
ATGGAACATTTGCTGAATCCGAAAGCAAGAGAGATCGAAATTTCAGGAATACGCAAATTCTCGAATCTTGTAGCCCAACA
CGAAGACGTCATTTCACTTACAATCGGCCAGCCTGATTTTTTCACACCGCATCATGTGAAAGCTGCCGCAAAAAAAGCCA
TTGATGAAAACGTGACGTCATATACTCCGAATGCCGGCTACCTGGAGCTGAGACAAGCTGTGCAGCTTTATATGAAGAAA
AAAGCGGATTTCAACTATGATGCTGAATCTGAAATTATCATCACAACAGGCGCAAGCCAAGCCATTGATGCTGCATTCCG
GACGATTTTATCTCCCGGTGATGAAGTCATTATGCCAGGGCCTATTTATCCGGGCTATGAACCTATTATCAATTTGTGCG
GGGCCAAGCCTGTCATTGTTGATACTACGTCACACGGCTTTAAGCTTACCGCCCGGCTGATTGAAGATGCTCTGACACCC
AACACCAAGTGTGTCGTGCTTCCTTATCCGTCAAACCCTACCGGCGTGACTTTATCTGAAGAAGAACTGAAAAGCATCGC
AGCTCTCTTAAAAGGCAGAAATGTCTTCGTATTGTCTGATGAAATATACAGTGAATTAACATATGACAGACCGCATTACT
CCATCGCAACCTATTTGCGGGATCAAACGATTGTCATTAACGGGTTGTCAAAATCACACAGCATGACCGGTTGGAGAATT
GGATTTTTATTTGCACCGAAAGACATTGCAAAGCACATTTTAAAGGTTCATCAATACAATGTGTCGTGCGCCTCATCCAT
TTCTCAAAAAGCCGCGCTTGAAGCTGTCACAAACGGCTTTGACGATGCATTGATTATGAGAGAACAATACAAAAAACGTC
TGGACTATGTTTATGACCGTCTTGTTTCCATGGGACTTGACGTAGTTAAACCGTCCGGTGCGTTTTATATCTTCCCTTCT
ATTAAATCATTTGGAATGACTTCATTTGATTTTAGTATGGCTCTTTTGGAAGACGCTGGCGTGGCACTCGTGCCGGGCAG
CTCGTTCTCAACATATGGTGAAGGATATGTAAGGCTGTCTTTTGCATGCTCAATGGACACGCTGAGAGAAGGCCTAGACC
GTTTAGAATTATTTGTATTAAAAAAACGTGAAGCAATGCAGACGATAAACAACGGCGTTTAA

Upstream 100 bases:

>100_bases
AAAGGCGCATACAATCGAAATATATCAGTTAAAAAGGTGACAAATGATCAGCTAGTGGTAAAATAGGATAAACTCATTAT
ATTTGTTAAGGTGATGAATT

Downstream 100 bases:

>100_bases
GCCGTTGTTTTTATTTTTTTGGAAATGAAATTTTAAACGCTGTGCCTTTTTCAGGATGGCTGTCCACATGTATAACTCCC
TGATGGTTTTCAATGATATT

Product: aminotransferase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MEHLLNPKAREIEISGIRKFSNLVAQHEDVISLTIGQPDFFTPHHVKAAAKKAIDENVTSYTPNAGYLELRQAVQLYMKK
KADFNYDAESEIIITTGASQAIDAAFRTILSPGDEVIMPGPIYPGYEPIINLCGAKPVIVDTTSHGFKLTARLIEDALTP
NTKCVVLPYPSNPTGVTLSEEELKSIAALLKGRNVFVLSDEIYSELTYDRPHYSIATYLRDQTIVINGLSKSHSMTGWRI
GFLFAPKDIAKHILKVHQYNVSCASSISQKAALEAVTNGFDDALIMREQYKKRLDYVYDRLVSMGLDVVKPSGAFYIFPS
IKSFGMTSFDFSMALLEDAGVALVPGSSFSTYGEGYVRLSFACSMDTLREGLDRLELFVLKKREAMQTINNGV

Sequences:

>Translated_393_residues
MEHLLNPKAREIEISGIRKFSNLVAQHEDVISLTIGQPDFFTPHHVKAAAKKAIDENVTSYTPNAGYLELRQAVQLYMKK
KADFNYDAESEIIITTGASQAIDAAFRTILSPGDEVIMPGPIYPGYEPIINLCGAKPVIVDTTSHGFKLTARLIEDALTP
NTKCVVLPYPSNPTGVTLSEEELKSIAALLKGRNVFVLSDEIYSELTYDRPHYSIATYLRDQTIVINGLSKSHSMTGWRI
GFLFAPKDIAKHILKVHQYNVSCASSISQKAALEAVTNGFDDALIMREQYKKRLDYVYDRLVSMGLDVVKPSGAFYIFPS
IKSFGMTSFDFSMALLEDAGVALVPGSSFSTYGEGYVRLSFACSMDTLREGLDRLELFVLKKREAMQTINNGV
>Mature_393_residues
MEHLLNPKAREIEISGIRKFSNLVAQHEDVISLTIGQPDFFTPHHVKAAAKKAIDENVTSYTPNAGYLELRQAVQLYMKK
KADFNYDAESEIIITTGASQAIDAAFRTILSPGDEVIMPGPIYPGYEPIINLCGAKPVIVDTTSHGFKLTARLIEDALTP
NTKCVVLPYPSNPTGVTLSEEELKSIAALLKGRNVFVLSDEIYSELTYDRPHYSIATYLRDQTIVINGLSKSHSMTGWRI
GFLFAPKDIAKHILKVHQYNVSCASSISQKAALEAVTNGFDDALIMREQYKKRLDYVYDRLVSMGLDVVKPSGAFYIFPS
IKSFGMTSFDFSMALLEDAGVALVPGSSFSTYGEGYVRLSFACSMDTLREGLDRLELFVLKKREAMQTINNGV

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI95147551, Length=400, Percent_Identity=27, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI169881279, Length=400, Percent_Identity=27, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI56713256, Length=401, Percent_Identity=27.1820448877805, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=27.1820448877805, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI169881281, Length=301, Percent_Identity=26.578073089701, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4507369, Length=378, Percent_Identity=25.1322751322751, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI7705897, Length=339, Percent_Identity=22.7138643067847, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI33469970, Length=339, Percent_Identity=22.7138643067847, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI187936925, Length=378, Percent_Identity=22.7513227513227, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI14211921, Length=378, Percent_Identity=22.7513227513227, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786816, Length=363, Percent_Identity=26.7217630853994, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1788722, Length=356, Percent_Identity=29.7752808988764, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1788627, Length=385, Percent_Identity=27.5324675324675, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787710, Length=324, Percent_Identity=26.8518518518519, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787909, Length=357, Percent_Identity=23.5294117647059, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790797, Length=394, Percent_Identity=22.3350253807107, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788332, Length=169, Percent_Identity=26.6272189349112, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=396, Percent_Identity=24.7474747474747, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=199, Percent_Identity=30.1507537688442, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=199, Percent_Identity=30.1507537688442, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17567369, Length=326, Percent_Identity=25.4601226993865, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534666, Length=352, Percent_Identity=24.7159090909091, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71981209, Length=354, Percent_Identity=23.4463276836158, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=397, Percent_Identity=26.1964735516373, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=358, Percent_Identity=24.5810055865922, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28573069, Length=383, Percent_Identity=25.8485639686684, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646114, Length=383, Percent_Identity=25.8485639686684, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573067, Length=383, Percent_Identity=25.8485639686684, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573065, Length=383, Percent_Identity=25.8485639686684, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI18859735, Length=388, Percent_Identity=23.9690721649485, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PATA_BACSU (P16524)

Other databases:

- EMBL:   AJ222587
- EMBL:   AL009126
- EMBL:   M29450
- PIR:   C69672
- RefSeq:   NP_389283.2
- ProteinModelPortal:   P16524
- SMR:   P16524
- EnsemblBacteria:   EBBACT00000000871
- GeneID:   939235
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14000
- GenoList:   BSU14000
- GeneTree:   EBGT00070000031834
- HOGENOM:   HBG645860
- ProtClustDB:   PRK07683
- BioCyc:   BSUB:BSU14000-MONOMER
- GO:   GO:0005737
- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PRINTS:   PR00753

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: 2.6.1.-

Molecular weight: Translated: 43536; Mature: 43536

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHLLNPKAREIEISGIRKFSNLVAQHEDVISLTIGQPDFFTPHHVKAAAKKAIDENVTS
CCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
YTPNAGYLELRQAVQLYMKKKADFNYDAESEIIITTGASQAIDAAFRTILSPGDEVIMPG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECC
PIYPGYEPIINLCGAKPVIVDTTSHGFKLTARLIEDALTPNTKCVVLPYPSNPTGVTLSE
CCCCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECH
EELKSIAALLKGRNVFVLSDEIYSELTYDRPHYSIATYLRDQTIVINGLSKSHSMTGWRI
HHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCEEE
GFLFAPKDIAKHILKVHQYNVSCASSISQKAALEAVTNGFDDALIMREQYKKRLDYVYDR
EEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LVSMGLDVVKPSGAFYIFPSIKSFGMTSFDFSMALLEDAGVALVPGSSFSTYGEGYVRLS
HHHCCCCEECCCCCEEEECCHHHCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEE
FACSMDTLREGLDRLELFVLKKREAMQTINNGV
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEHLLNPKAREIEISGIRKFSNLVAQHEDVISLTIGQPDFFTPHHVKAAAKKAIDENVTS
CCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
YTPNAGYLELRQAVQLYMKKKADFNYDAESEIIITTGASQAIDAAFRTILSPGDEVIMPG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEECC
PIYPGYEPIINLCGAKPVIVDTTSHGFKLTARLIEDALTPNTKCVVLPYPSNPTGVTLSE
CCCCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECH
EELKSIAALLKGRNVFVLSDEIYSELTYDRPHYSIATYLRDQTIVINGLSKSHSMTGWRI
HHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCEEE
GFLFAPKDIAKHILKVHQYNVSCASSISQKAALEAVTNGFDDALIMREQYKKRLDYVYDR
EEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LVSMGLDVVKPSGAFYIFPSIKSFGMTSFDFSMALLEDAGVALVPGSSFSTYGEGYVRLS
HHHCCCCEECCCCCEEEECCHHHCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCEEEEE
FACSMDTLREGLDRLELFVLKKREAMQTINNGV
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615