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The map label for this gene is dppE

Identifier: 255767302

GI number: 255767302

Start: 1364151

End: 1365800

Strand: Direct

Name: dppE

Synonym: BSU12960

Alternate gene names: 255767302

Gene position: 1364151-1365800 (Clockwise)

Preceding gene: 16078360

Following gene: 255767303

Centisome position: 32.36

GC content: 44.67

Gene sequence:

>1650_bases
ATGAAAAGGGGGAAGAGGATGAAACGAGTGAAAAAGCTATGGGGCATGGGTCTTGCATTAGGACTTTCGTTTGCGCTGAT
GGGGTGCACAGCAAATGAACAGGCCGGAAAAGAAGGCAGTCATGATAAGGCAAAAACCAGCGGAGAAAAGGTGCTGTATG
TAAATAATGAAAATGAACCGACTTCATTCGATCCGCCGATCGGCTTTAATAATGTGTCATGGCAGCCGTTAAATAACATC
ATGGAGGGGCTGACGCGTCTTGGCAAAGATCATGAGCCCGAGCCGGCAATGGCGGAGAAATGGTCTGTTTCGAAAGATAA
TAAAACTTACACATTTACGATTCGGGAAAATGCGAAATGGACAAACGGAGATCCTGTAACAGCCGGAGACTTCGAATACG
CGTGGAAGCGGATGCTTGATCCGAAAAAAGGCGCTTCATCGGCATTCCTAGGTTATTTTATTGAAGGCGGCGAAGCATAT
AACAGCGGGAAAGGGAAAAAAGACGATGTGAAGGTGACGGCAAAGGATGATCGAACCCTTGAAGTTACACTGGAAGCACC
GCAAAAATATTTCCTGAGCGTTGTGTCCAATCCCGCGTATTTCCCGGTAAATGAAAAGGTCGATAAAGACAATCCAAAGT
GGTTTGCTGAGTCGGATACATTTGTCGGAAACGGCCCGTTTAAGCTGACGGAATGGAAGCATGATGACAGCATCACAATG
GAGAAAAGCGACACGTATTGGGATAAGGATACAGTGAAGCTTGATAAGGTGAAATGGGCGATGGTCAGTGACAGAAATAC
AGATTACCAGATGTTTCAATCAGGGGAACTTGATACCGCTTATGTCCCTGCTGAGCTGAGTGATCAGCTGCTTGATCAGG
ATAACGTCAATATTGTTGACCAGGCGGGTCTCTATTTCTATCGATTTAATGTCAACATGGAGCCGTTCCAAAATGAAAAC
ATCAGAAAAGCCTTTGCGATGGCTGTGGATCAAGAGGAAATTGTAAAGTACGTCACGAAAAATAATGAAAAACCGGCGCA
CGCCTTTGTATCGCCTGGGTTTACGCAGCCTGACGGCAAAGATTTCCGTGAAGCAGGCGGAGACCTGATCAAGCCTAACG
AAAGCAAAGCGAAGCAGCTGCTCGAAAAGGGCATGAAGGAAGAAAACTATAATAAGCTTCCTGCGATCACGCTTACTTAC
AGCACAAAGCCGGAGCATAAAAAGATTGCCGAAGCTATTCAGCAAAAATTGAAAAATAGCCTTGGAGTCGATGTGAAGCT
GGCCAATATGGAATGGAACGTATTTTTAGAGGATCAAAAAGCGCTGAAATTCCAATTCTCTCAAAGCTCATTTTTGCCTG
ATTATGCAGACCCTATCAGTTTTCTGGAAGCCTTTCAAACGGGAAATTCGATGAACCGCACAGGCTGGGCCAATAAAGAA
TACGATCAGCTGATCAAACAGGCGAAAAACGAAGCCGATGAAAAAACACGGTTCTCTCTTATGCATCAAGCTGAAGAGCT
GCTCATCAATGAAGCGCCGATCATTCCGGTTTATTTTTATAATCAGGTTCACCTGCAAAATGAACAAGTAAAAGGAATTG
TCCGTCACCCTGTCGGCTATATCGATTTAAAATGGGCAGATAAAAACTGA

Upstream 100 bases:

>100_bases
CGGGCCAGACGATCAGATCTGACTCGCACACCGTCAACTGCTGGCTGCAGGATCAACGAGCAGAGCATGCGGTGCTGTCA
GGAGATGCGAAGGATTGAAC

Downstream 100 bases:

>100_bases
TGGAGGCGATTGAGGAAATACTGCTTCTTTATGCGAAGGAGCGGTATTTTTTCTCTTTCTTGCACGTATACGTAGGGTGC
AGAGCAAATGAAAGGAGTGT

Product: dipeptide ABC transporter dipeptide-binding lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKRGKRMKRVKKLWGMGLALGLSFALMGCTANEQAGKEGSHDKAKTSGEKVLYVNNENEPTSFDPPIGFNNVSWQPLNNI
MEGLTRLGKDHEPEPAMAEKWSVSKDNKTYTFTIRENAKWTNGDPVTAGDFEYAWKRMLDPKKGASSAFLGYFIEGGEAY
NSGKGKKDDVKVTAKDDRTLEVTLEAPQKYFLSVVSNPAYFPVNEKVDKDNPKWFAESDTFVGNGPFKLTEWKHDDSITM
EKSDTYWDKDTVKLDKVKWAMVSDRNTDYQMFQSGELDTAYVPAELSDQLLDQDNVNIVDQAGLYFYRFNVNMEPFQNEN
IRKAFAMAVDQEEIVKYVTKNNEKPAHAFVSPGFTQPDGKDFREAGGDLIKPNESKAKQLLEKGMKEENYNKLPAITLTY
STKPEHKKIAEAIQQKLKNSLGVDVKLANMEWNVFLEDQKALKFQFSQSSFLPDYADPISFLEAFQTGNSMNRTGWANKE
YDQLIKQAKNEADEKTRFSLMHQAEELLINEAPIIPVYFYNQVHLQNEQVKGIVRHPVGYIDLKWADKN

Sequences:

>Translated_549_residues
MKRGKRMKRVKKLWGMGLALGLSFALMGCTANEQAGKEGSHDKAKTSGEKVLYVNNENEPTSFDPPIGFNNVSWQPLNNI
MEGLTRLGKDHEPEPAMAEKWSVSKDNKTYTFTIRENAKWTNGDPVTAGDFEYAWKRMLDPKKGASSAFLGYFIEGGEAY
NSGKGKKDDVKVTAKDDRTLEVTLEAPQKYFLSVVSNPAYFPVNEKVDKDNPKWFAESDTFVGNGPFKLTEWKHDDSITM
EKSDTYWDKDTVKLDKVKWAMVSDRNTDYQMFQSGELDTAYVPAELSDQLLDQDNVNIVDQAGLYFYRFNVNMEPFQNEN
IRKAFAMAVDQEEIVKYVTKNNEKPAHAFVSPGFTQPDGKDFREAGGDLIKPNESKAKQLLEKGMKEENYNKLPAITLTY
STKPEHKKIAEAIQQKLKNSLGVDVKLANMEWNVFLEDQKALKFQFSQSSFLPDYADPISFLEAFQTGNSMNRTGWANKE
YDQLIKQAKNEADEKTRFSLMHQAEELLINEAPIIPVYFYNQVHLQNEQVKGIVRHPVGYIDLKWADKN
>Mature_549_residues
MKRGKRMKRVKKLWGMGLALGLSFALMGCTANEQAGKEGSHDKAKTSGEKVLYVNNENEPTSFDPPIGFNNVSWQPLNNI
MEGLTRLGKDHEPEPAMAEKWSVSKDNKTYTFTIRENAKWTNGDPVTAGDFEYAWKRMLDPKKGASSAFLGYFIEGGEAY
NSGKGKKDDVKVTAKDDRTLEVTLEAPQKYFLSVVSNPAYFPVNEKVDKDNPKWFAESDTFVGNGPFKLTEWKHDDSITM
EKSDTYWDKDTVKLDKVKWAMVSDRNTDYQMFQSGELDTAYVPAELSDQLLDQDNVNIVDQAGLYFYRFNVNMEPFQNEN
IRKAFAMAVDQEEIVKYVTKNNEKPAHAFVSPGFTQPDGKDFREAGGDLIKPNESKAKQLLEKGMKEENYNKLPAITLTY
STKPEHKKIAEAIQQKLKNSLGVDVKLANMEWNVFLEDQKALKFQFSQSSFLPDYADPISFLEAFQTGNSMNRTGWANKE
YDQLIKQAKNEADEKTRFSLMHQAEELLINEAPIIPVYFYNQVHLQNEQVKGIVRHPVGYIDLKWADKN

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=485, Percent_Identity=32.1649484536082, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1787495, Length=531, Percent_Identity=31.8267419962335, Blast_Score=242, Evalue=5e-65,
Organism=Escherichia coli, GI1789397, Length=502, Percent_Identity=30.0796812749004, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1787762, Length=507, Percent_Identity=24.8520710059172, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789966, Length=551, Percent_Identity=25.7713248638838, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1787052, Length=552, Percent_Identity=23.9130434782609, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1787551, Length=481, Percent_Identity=21.6216216216216, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789887, Length=491, Percent_Identity=23.0142566191446, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 62576; Mature: 62576

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRGKRMKRVKKLWGMGLALGLSFALMGCTANEQAGKEGSHDKAKTSGEKVLYVNNENEP
CCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHCCCCCCCCHHHCCCCEEEEECCCCCC
TSFDPPIGFNNVSWQPLNNIMEGLTRLGKDHEPEPAMAEKWSVSKDNKTYTFTIRENAKW
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEEEEEECCCCC
TNGDPVTAGDFEYAWKRMLDPKKGASSAFLGYFIEGGEAYNSGKGKKDDVKVTAKDDRTL
CCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCEECCCCCCCCCEEEEECCCCEE
EVTLEAPQKYFLSVVSNPAYFPVNEKVDKDNPKWFAESDTFVGNGPFKLTEWKHDDSITM
EEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCEECCCCEEEEEECCCCCEEE
EKSDTYWDKDTVKLDKVKWAMVSDRNTDYQMFQSGELDTAYVPAELSDQLLDQDNVNIVD
ECCCCCCCCCCEEEEEEEEEEECCCCCCHHHHCCCCCCEEEECHHHHHHHHCCCCCCEEE
QAGLYFYRFNVNMEPFQNENIRKAFAMAVDQEEIVKYVTKNNEKPAHAFVSPGFTQPDGK
CCCEEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCC
DFREAGGDLIKPNESKAKQLLEKGMKEENYNKLPAITLTYSTKPEHKKIAEAIQQKLKNS
HHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
LGVDVKLANMEWNVFLEDQKALKFQFSQSSFLPDYADPISFLEAFQTGNSMNRTGWANKE
CCCEEEEECEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHH
YDQLIKQAKNEADEKTRFSLMHQAEELLINEAPIIPVYFYNQVHLQNEQVKGIVRHPVGY
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEEECCHHHHHHHHCCCCE
IDLKWADKN
EEEEECCCC
>Mature Secondary Structure
MKRGKRMKRVKKLWGMGLALGLSFALMGCTANEQAGKEGSHDKAKTSGEKVLYVNNENEP
CCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHCCCCCCCCHHHCCCCEEEEECCCCCC
TSFDPPIGFNNVSWQPLNNIMEGLTRLGKDHEPEPAMAEKWSVSKDNKTYTFTIRENAKW
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEEEEEECCCCC
TNGDPVTAGDFEYAWKRMLDPKKGASSAFLGYFIEGGEAYNSGKGKKDDVKVTAKDDRTL
CCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCEECCCCCCCCCEEEEECCCCEE
EVTLEAPQKYFLSVVSNPAYFPVNEKVDKDNPKWFAESDTFVGNGPFKLTEWKHDDSITM
EEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCEECCCCEEEEEECCCCCEEE
EKSDTYWDKDTVKLDKVKWAMVSDRNTDYQMFQSGELDTAYVPAELSDQLLDQDNVNIVD
ECCCCCCCCCCEEEEEEEEEEECCCCCCHHHHCCCCCCEEEECHHHHHHHHCCCCCCEEE
QAGLYFYRFNVNMEPFQNENIRKAFAMAVDQEEIVKYVTKNNEKPAHAFVSPGFTQPDGK
CCCEEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCC
DFREAGGDLIKPNESKAKQLLEKGMKEENYNKLPAITLTYSTKPEHKKIAEAIQQKLKNS
HHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
LGVDVKLANMEWNVFLEDQKALKFQFSQSSFLPDYADPISFLEAFQTGNSMNRTGWANKE
CCCEEEEECEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHH
YDQLIKQAKNEADEKTRFSLMHQAEELLINEAPIIPVYFYNQVHLQNEQVKGIVRHPVGY
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEEECCHHHHHHHHCCCCE
IDLKWADKN
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]