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The map label for this gene is argC

Identifier: 255767251

GI number: 255767251

Start: 1195034

End: 1196071

Strand: Direct

Name: argC

Synonym: BSU11190

Alternate gene names: 255767251

Gene position: 1195034-1196071 (Clockwise)

Preceding gene: 16078183

Following gene: 255767252

Centisome position: 28.35

GC content: 46.24

Gene sequence:

>1038_bases
TTGAAAATAGGAATTGTAGGTGCTACAGGATATGGAGGCACCGAACTTGTCAGGATTCTTTCGCATCATCCTCATGCAGA
GGAATGCATACTTTATTCATCCAGCGGAGAAGGGAATGTCTATAGCGAGGGTTATCCTCATCTTACCGGCTTAGCGGATC
AGCAGCTGAAGCCGATTGATATGAATACGATCAAACACGAAATAGATATCATGTTTCTCGCTGCGCCGCCCGGAGTATCA
AGTGAATTGACTCCAAAGCTGGCAGACGCGGGAATTACGGTTATTGATCTGTCAGGTGATCTGAGGATAAAAGAACCGGC
TGAATATGAAAAATGGTATAAACGGACAGCGGCACCGAAGGCGGTGATTCAAGAGGCGGTATACGGTCTGGCAGAACTGA
ATCAACTGCAAATTCAACAGGCGAAACTCATTGCCAATCCAGGCTGTTTTCCAACAGCTGTTTTGCTTGGCCTCGCGCCA
TTGGCTCAAAAGAAACTGCTCGATGAATCTTTCGTTATCGTTGACGCGAAGACCGGTGTTTCCGGAGCGGGAAGAAAAGC
ATCCATGGGAACTCATTTTTCTGAGCTGAACGACAATTTTAAAATTTATAAAGTCAATGAACATCAGCACACGCCGGAAA
TTGAGCAGGCGCTGAATGAATGGCAGCCAGGTCTCGGGCCCATTACATTTTCGGCTCACTTGGTTCCGATGACAAGGGGC
ATCATGGCGACGATGTATACCAGATTAACCTGTGACCTAACCGCAGATGACCTGCATGATTTATATTCGGAATTTTACCA
AGATTCATATTTTGTGAGAGTGAGGCCAAAAGGTCAGTACCCGCAAACGAAAGAAGTGTACGGCAGCAATTTCTGTGATA
TCGCCGTGACCCTCGATGAGAGAACGAACAGAGTCACGATCGTCTCGGTAATCGATAATTTAATGAAGGGTGCCGCCGGT
CAGGCAGTGCAAAACTTTAATTTGATGAATGGCTGGAATGAAGAAACTGGACTCACCATCACGCCAATTTATCCATAG

Upstream 100 bases:

>100_bases
ATTTATAAATGAATAAAAATATTAAATATACGATTGAATTAATTTTTATTCATGTTATAATGTTAAATAATTTCACAAAG
ACCAAGAGGGTGAACTTGTT

Downstream 100 bases:

>100_bases
AACGGGAGAGAATCGAACCATGATTCAGTTAAGTGAAGATCAAATTGTAAAAGTAACAGGTGATGTATCCTCGCCAAAAG
GGTTTCAGGCAAAGGGTGTG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKIGIVGATGYGGTELVRILSHHPHAEECILYSSSGEGNVYSEGYPHLTGLADQQLKPIDMNTIKHEIDIMFLAAPPGVS
SELTPKLADAGITVIDLSGDLRIKEPAEYEKWYKRTAAPKAVIQEAVYGLAELNQLQIQQAKLIANPGCFPTAVLLGLAP
LAQKKLLDESFVIVDAKTGVSGAGRKASMGTHFSELNDNFKIYKVNEHQHTPEIEQALNEWQPGLGPITFSAHLVPMTRG
IMATMYTRLTCDLTADDLHDLYSEFYQDSYFVRVRPKGQYPQTKEVYGSNFCDIAVTLDERTNRVTIVSVIDNLMKGAAG
QAVQNFNLMNGWNEETGLTITPIYP

Sequences:

>Translated_345_residues
MKIGIVGATGYGGTELVRILSHHPHAEECILYSSSGEGNVYSEGYPHLTGLADQQLKPIDMNTIKHEIDIMFLAAPPGVS
SELTPKLADAGITVIDLSGDLRIKEPAEYEKWYKRTAAPKAVIQEAVYGLAELNQLQIQQAKLIANPGCFPTAVLLGLAP
LAQKKLLDESFVIVDAKTGVSGAGRKASMGTHFSELNDNFKIYKVNEHQHTPEIEQALNEWQPGLGPITFSAHLVPMTRG
IMATMYTRLTCDLTADDLHDLYSEFYQDSYFVRVRPKGQYPQTKEVYGSNFCDIAVTLDERTNRVTIVSVIDNLMKGAAG
QAVQNFNLMNGWNEETGLTITPIYP
>Mature_345_residues
MKIGIVGATGYGGTELVRILSHHPHAEECILYSSSGEGNVYSEGYPHLTGLADQQLKPIDMNTIKHEIDIMFLAAPPGVS
SELTPKLADAGITVIDLSGDLRIKEPAEYEKWYKRTAAPKAVIQEAVYGLAELNQLQIQQAKLIANPGCFPTAVLLGLAP
LAQKKLLDESFVIVDAKTGVSGAGRKASMGTHFSELNDNFKIYKVNEHQHTPEIEQALNEWQPGLGPITFSAHLVPMTRG
IMATMYTRLTCDLTADDLHDLYSEFYQDSYFVRVRPKGQYPQTKEVYGSNFCDIAVTLDERTNRVTIVSVIDNLMKGAAG
QAVQNFNLMNGWNEETGLTITPIYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=339, Percent_Identity=37.7581120943953, Blast_Score=204, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6320913, Length=342, Percent_Identity=28.0701754385965, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_BACSU (P23715)

Other databases:

- EMBL:   X52834
- EMBL:   Z26919
- EMBL:   Z79580
- EMBL:   Y09476
- EMBL:   AL009126
- EMBL:   M15420
- PIR:   I40372
- RefSeq:   NP_389001.2
- ProteinModelPortal:   P23715
- SMR:   P23715
- EnsemblBacteria:   EBBACT00000003101
- GeneID:   936389
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU11190
- GenoList:   BSU11190
- GeneTree:   EBGT00050000002599
- HOGENOM:   HBG294213
- ProtClustDB:   PRK00436
- BioCyc:   BSUB:BSU11190-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37961; Mature: 37961

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGIVGATGYGGTELVRILSHHPHAEECILYSSSGEGNVYSEGYPHLTGLADQQLKPID
CEEEEEEECCCCHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
MNTIKHEIDIMFLAAPPGVSSELTPKLADAGITVIDLSGDLRIKEPAEYEKWYKRTAAPK
HHHHEEEEEEEEEECCCCCCCCCCCHHHHCCEEEEECCCCEEECCCHHHHHHHHHHCCHH
AVIQEAVYGLAELNQLQIQQAKLIANPGCFPTAVLLGLAPLAQKKLLDESFVIVDAKTGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
SGAGRKASMGTHFSELNDNFKIYKVNEHQHTPEIEQALNEWQPGLGPITFSAHLVPMTRG
CCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEEHHHHHH
IMATMYTRLTCDLTADDLHDLYSEFYQDSYFVRVRPKGQYPQTKEVYGSNFCDIAVTLDE
HHHHHHHHEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCEEEEEEECC
RTNRVTIVSVIDNLMKGAAGQAVQNFNLMNGWNEETGLTITPIYP
CCCCEEHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MKIGIVGATGYGGTELVRILSHHPHAEECILYSSSGEGNVYSEGYPHLTGLADQQLKPID
CEEEEEEECCCCHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
MNTIKHEIDIMFLAAPPGVSSELTPKLADAGITVIDLSGDLRIKEPAEYEKWYKRTAAPK
HHHHEEEEEEEEEECCCCCCCCCCCHHHHCCEEEEECCCCEEECCCHHHHHHHHHHCCHH
AVIQEAVYGLAELNQLQIQQAKLIANPGCFPTAVLLGLAPLAQKKLLDESFVIVDAKTGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
SGAGRKASMGTHFSELNDNFKIYKVNEHQHTPEIEQALNEWQPGLGPITFSAHLVPMTRG
CCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEEHHHHHH
IMATMYTRLTCDLTADDLHDLYSEFYQDSYFVRVRPKGQYPQTKEVYGSNFCDIAVTLDE
HHHHHHHHEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCEEEEEEECC
RTNRVTIVSVIDNLMKGAAGQAVQNFNLMNGWNEETGLTITPIYP
CCCCEEHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2117746; 8025667; 9025291; 9353931; 9384377; 3106155